Genetic polymorphism of metabolic enzymes P450 (CYP) as a susceptibility factor for drug response, toxicity, and cancer risk

Arhiv za Higijenu Rada i Toksikologiju

Volumn 60, Issue 2, 2009, Pages 217-242

  Božina, Nada ^a,b   Bradamante, Vlasta ^b   Lovrić, Mila ^a  

^a KBC Zagreb   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Cancer risk; Cytochrome P450; Drug metabolism; Genotyping; Pharmacogenomics; Polymorphic allele; Xenobiotics

Indexed keywords

BARBITURIC ACID DERIVATIVE; CITALOPRAM; CLOMIPRAMINE; CODEINE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 ISOENZYME; DIAZEPAM; FENTANYL; IMIPRAMINE; LANSOPRAZOLE; MOCLOBEMIDE; OMEPRAZOLE; PANTOPRAZOLE; PHENYTOIN; PROGUANIL; PROPRANOLOL; RITONAVIR; SERTRALINE; TOLBUTAMIDE; UNINDEXED DRUG; VALPROIC ACID; XENOBIOTIC AGENT;

CANCER RISK; CANCER SUSCEPTIBILITY; CHEMICAL CARCINOGENESIS; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME POLYMORPHISM; ENZYME SPECIFICITY; GENE FREQUENCY; GENOTYPE; HUMAN; NONHUMAN; PHARMACOGENOMICS; REVIEW; RISK ASSESSMENT; TISSUE DISTRIBUTION; XENOBIOTIC METABOLISM;

CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; GENETIC PREDISPOSITION TO DISEASE; HUMANS; NEOPLASMS; PHARMACOGENETICS; POLYMORPHISM, GENETIC; XENOBIOTICS;

EID: 67749127877     PISSN: 00041254     EISSN: None     Source Type: Journal    
DOI: 10.2478/10004-1254-60-2009-1885     Document Type: Review

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