The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: Consequences for occupational and environmental medicine

International Archives of Occupational and Environmental Health

Volumn 76, Issue 3, 2003, Pages 174-185

  Bolt, Hermann M ^a   Roos, Peter H ^a   Thier, Ricarda ^b  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Acrylamide; Acrylonitrile; CYP2E1; Cytochrome P 450; Industrial chemicals; Inter ethnic variability; Inter individual variability; n Hexane, 1,3 butadiene

Indexed keywords

1,3 BUTADIENE; ACETALDEHYDE; ACETONE; ACETYLSALICYLIC ACID; ACRYLAMIDE; ACRYLONITRILE; ALCOHOL; ALIPHATIC HYDROCARBON; ALKANE DERIVATIVE; ALKENE DERIVATIVE; ANILINE; AROMATIC HYDROCARBON; CAFFEINE; CHLORZOXAZONE; CLOMETHIAZOLE; CYTOCHROME P450 2E1; DAPSONE; DISULFIRAM; ENFLURANE; FATTY ACID; GLYCEROL; HALOGENATED HYDROCARBON; HEXANE; PARACETAMOL; PYRAZOLE; SOLVENT; STYRENE; TRICHLOROETHYLENE; UNINDEXED DRUG; VINYL CHLORIDE;

ACUTE TOXICITY; ALLELE; ASIAN; BIOLOGICAL MONITORING; CHEMICAL INDUSTRY; DNA FLANKING REGION; DRUG HYDROXYLATION; ENVIRONMENTAL PARAMETERS; ENZYME ACTIVITY; ENZYME INHIBITION; EPIDEMIOLOGICAL DATA; ETHNIC DIFFERENCE; EUROPE; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; INTRON; JAPAN; NONHUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL MEDICINE; PHENOTYPE; POPULATION; PROTEIN EXPRESSION; REVIEW; TOXICITY; WORKER;

EID: 0037938645     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-002-0407-4     Document Type: Review

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