The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes

Life Sciences

Volumn 79, Issue 26, 2006, Pages 2432-2440

  Yao, Hsien Tsung ^a   Chang, Yi Wei ^a   Lan, Shih Jung ^a   Chen, Chiung Tong ^a   Hsu, John T A ^a   Yeh, Teng Kuang ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Cytochrome P450; Inhibition; Metabolism; Polyunsaturated fatty acids

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID; PALMITIC ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; STEARIC ACID;

ARTICLE; BACULOVIRUS; ENZYME INHIBITION; IC 50; INCUBATION TIME;

ALPHA-LINOLENIC ACID; ANIMALS; ARACHIDONIC ACID; ARYL HYDROCARBON HYDROXYLASES; CATALYSIS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSAPENTAENOIC ACID; FATTY ACIDS, UNSATURATED; HUMANS; KINETICS; LINOLEIC ACID; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; PALMITIC ACID; STEARIC ACIDS;

EID: 33751205342     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.08.016     Document Type: Article

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