Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers

Toxicology

Volumn 239, Issue 1-2, 2007, Pages 34-44

  Hsieh, Hui I ^a,b   Chen, Pau Chung ^a   Wong, Ruey Hong ^c   Wang, Jung Der ^a,d   Yang, Pei Ming ^d   Cheng, Tsun Jen ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CATHAY GENERAL HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Liver fibrosis; Metabolizing genetic polymorphisms; Occupational exposure; Vinyl chloride monomer

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; CYTOCHROME P450 2E1; GLUTATHIONE TRANSFERASE T1; POLYVINYLCHLORIDE;

ADULT; ARTICLE; CALCULATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ECHOGRAPHY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LIVER FIBROSIS; LIVER INJURY; MALE; METABOLISM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT;

ADULT; AIR POLLUTANTS, OCCUPATIONAL; ALDEHYDE DEHYDROGENASE; CARCINOGENS; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; LIVER CIRRHOSIS; OCCUPATIONAL EXPOSURE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK ASSESSMENT; TAIWAN; VINYL CHLORIDE;

EID: 34548119844     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.06.089     Document Type: Article

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