Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism

Molecular Pharmacology

Volumn 62, Issue 1, 2002, Pages 162-172

  Lin, Yvonne S ^a,b   Dowling, Amy L S ^a,b   Quigley, Sean D ^a,b   Farin, Federico M ^a,b   Zhang, Jiong ^a,b   Lamba, Jatinder ^a,b   Schuetz, Erin G ^a,b   Thummel, Kenneth E ^a,b,c  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; MIDAZOLAM;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; DRUG HYDROXYLATION; DRUG METABOLISM; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENOTYPE; HUMAN; HUMAN TISSUE; JEJUNUM MUCOSA; LIVER; MALE; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RNA ANALYSIS; RNA SPLICING; SCHOOL CHILD; SEX DIFFERENCE;

ALLELES; ANTI-ANXIETY AGENTS; BASE SEQUENCE; CYTOCHROME P-450 ENZYME SYSTEM; GENOTYPE; HEPATOCYTES; HUMANS; HYDROXYLATION; INTESTINE, SMALL; MICROSOMES, LIVER; MIDAZOLAM; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; PHENOTYPE; RNA, MESSENGER; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0036089341     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.1.162     Document Type: Article

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