Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease

Clinica Chimica Acta

Volumn 382, Issue 1-2, 2007, Pages 37-42

  Arif, Ehtesham ^a,c   Vibhuti, Arpana ^a   Alam, Pervez ^a   Deepak, Desh ^b   Singh, Bhawani ^b   Athar, Mohammad ^c   Pasha, M A Qadar ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b DR RAM MANOHAR LOHIA HOSPITAL   (India)

^c HAMDARD UNIVERSITY   (India)

Author keywords

Chronic obstructive pulmonary disease; Cytochrome p 450; Detoxification; N acetyl transferase 2; Polymorphisms

Indexed keywords

ACYLTRANSFERASE; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1;

ADULT; ALLELE; ANALYSIS; ARTICLE; BIOSTATISTICS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYP2E1 GENE; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; GENE; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAT2 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STATISTICAL SIGNIFICANCE;

AGED; ARYLAMINE N-ACETYLTRANSFERASE; CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP2E1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIA; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 34249007800     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2007.03.013     Document Type: Article

References (32)

1. Snider G. Chronic obstructive pulmonary disease: risk factors, pathophysiology and pathogenesis. Annu Rev Med 40 (1989) 411-429
2. Barnes P.J. Chronic obstructive pulmonary disease. N Engl J Med 343 (2000) 269-280
3. MacNee W., and Rahman I. Oxidants and antioxidants as therapeutic targets in COPD. Am J Respir Crit Care Med 160 (1999) S58-S65
4. Gonzalez M.V., Alvarez V., Pello M.F., Menendez M.J., Suarez C., and Coto E. Genetic polymorphism of N-acetyltransferase-2, glutathione S-transferase-M1, and cytochromes P450IIE1 and P450IID6 in the susceptibility to head and neck cancer. J Clin Pathol 51 (1998) 294-298
5. Smith C.A., Smith G., and Wolf C.R. Genetic polymorphisms in xenobiotic metabolism. Eur J Cancer 30A (1994) 1921-1935
6. Hecht S.S. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol 11 (1998) 560-603
7. Smith C.A., Moss J.E., Gough A.C., Spurr N.K., and Wolf C.R. Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility. Environ Health Perspect 98 (1992) 107-112
8. Ronis M.J.J., Lindros K.O., and Ingelman-Sundberg M. The CYP2E1 subfamily. In: Ioannides C. (Ed). Cytochromes P450: metabolic and toxicological agents (1996), CRC Press, Boca Raton, FL 212-239
9. Hayashi S., Watanabe J., and Kawajiri K. Genetic polymorphisms in the 5′ flanking region change transcriptional regulation of the human cytochrome P4502E1 gene. J Biochem 110 (1991) 559-565
10. *2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men. Exp Mol Pathol 74 (2003) 183-189
11. Sikdar N., Mahmud S.A., Paul R.R., and Roy B. Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users. Cancer Lett 195 (2003) 33-42
12. Wu X., Amos C.I., Kemp B.L., et al. Cytochrome P450 2E1 DraI polymorphisms in lung cancer in minority populations. Cancer Epidemiol Biomark Prev 7 (1998) 13-18
13. Tsutsumi M., Wang J.S., Takase S., and Takada A. Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P-4502E1 genotypes. Alcohol Alcohol 29 (1994) 29-32
14. Hein D.W., Doll M.A., Rustan T.D., and Ferguson R.J. Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions. Cancer Res 55 (1995) 3531-3536
15. Yu M.W., Pai C.I., Yang S.Y., et al. Role of N-acetyltransferase polymorphisms in hepatitis B related hepatocellular carcinoma: impact of smoking on risk. Gut 47 (2000) 703-709
16. Alberg A.J., Daudt A., Huang H.Y., et al. N-acetyltransferase 2 (NAT2) genotypes, cigarette smoking and the risk of breast cancer. Cancer Detec Prev 28 (2004) 187-193
17. Chen C., Ricks S., Doody D.R., Fitzgibbons E.D., Porter P.L., and Schwartz S.M. N-Acetyltransferase 2 polymorphisms, cigarette smoking and alcohol consumption, and oral squamous cell cancer risk. Carcinogenesis 22 (2001) 1993-1999
18. Brockton N., Little J., Sharp L., and Cotton S.C. N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review. Am J Epidemiol 151 (2000) 846-861
19. Nacak M., Aynacioglu A.S., Filiz A., et al. Association between the N-acetylation genetic polymorphism and bronchial asthma. Br J Clin Pharmacol 54 (2002) 671-674
20. Batra J., Sharma S.K., and Ghosh B. Arylamine N-acetyltransferase gene polymorphisms: markers for atopic asthma, serum IgE and blood eosinophil counts. Pharmacogenomics 7 (2006) 673-682
21. Gaspar P., Moreira J., Kvitko K., Torres, Moreira A., and Weimer T. CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell lung cancer?. Genet Mol Biol 27 (2004) 133-138
22. American Thoracic Society. Standardization of spirometry. Am Rev Respir Dis 136 (1987) 1285-1298
23. Reis A.L. Response to bronchodilators. In: Clausen J. (Ed). Pulmonary function testing: guidelines and controversies (1982), Academics Press, New York 215-221
24. Wong N.A.C.S., Rae F., Simpson K.J., Murray G.D., and Harrison D.J. Genetic polymorphisms of cytochrome p4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: a study and literature review, including meta-analysis. Mol Pathol 53 (2000) 88-93
25. Wolf C.R., Smith C.A., Bishop T., Forman D., Gough A.C., and Spurr N.K. CYP2D6 genotyping and the association with lung cancer susceptibility. Pharmacogenetics 4 (1994) 104-106
26. Smith C.A., Wadelius M., Gough A.C., Harrison D.J., Wolf C.R., and Rane A. A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid. J Med Genet 34 (1997) 758-760
27. Vatsis K.P., Weber W.W., Bell D.A., et al. Nomenclature for N-acetyltransferases. Pharmacogenetics 5 (1995) 1-7
28. Cantlay A.M., Lamb D., and Gillooly M. Association between the CYP1A1 gene polymorphims and susceptibility to emphysema and lung cancer. J Clin Mol Pathol 48 (1995) M210-M214
29. Brogger J., Steen V.M., Eiken H.G., Gulsvik A., and Bakke P. Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1. Eur Respir J 27 (2006) 682-688
30. Cheng S.L., Yu C.J., Chen C.J., and Yang P.C. Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD. Eur Respir J 23 (2004) 818-824
31. Watanabe J., Hayashi S., and Kawajiri K. Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region. J Biochem 116 (1994) 321-326
32. Wan J., Shi J., Hui L., et al. Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning. Environ Health Perspect 110 (2002) 1213-1218