메뉴 건너뛰기




Volumn 9, Issue 4, 2009, Pages 457-470

Anticancer actions of omega-3 fatty acids - Current state and future perspectives

Author keywords

Apoptosis; Cancer; Cyclooxygenase; Docosahexaenoic acid; Eicosanoids; Eicosapentaenoic acid; Lipid peroxidation; Omega 3 fatty acids

Indexed keywords

ANTINEOPLASTIC AGENT; CD59 ANTIGEN; CYCLOOXYGENASE 2; DNA POLYMERASE; DNA TOPOISOMERASE; DOCOSAHEXAENOIC ACID; DOXORUBICIN; FLUOROURACIL; GENISTEIN; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOTRIENE; LIPOXIN; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; OMEGA 9 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN P53; RESOLVIN; THROMBOXANE; UNCLASSIFIED DRUG; VINCRISTINE; RESOLVIN D1;

EID: 67649804559     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/1871520610909040457     Document Type: Review
Times cited : (97)

References (204)
  • 1
    • 85036833413 scopus 로고    scopus 로고
    • Uniting to defeat cancer. International Union against cancer, Annual report, 2007.
    • Uniting to defeat cancer. International Union against cancer, Annual report, 2007.
  • 2
    • 21444443059 scopus 로고    scopus 로고
    • Norat, T.; Bingham, S.; Ferrari, P.; Sliman, N.; Jenab, M.; Mazuir, M.; Overvad, K.; Olsen, A.; Tjonneland, A.; Clavel, F.; Boutron-Ruault, M.C.; Kesse, E.; Boeing, H.; Bergmann, M.M.; Nieters, A.; Linseisen, J.; Trichopoulou, A.; Trichopoulos, D.; Tountas, Y.; Berrino, F., Palli, D.; Panico, S.; Tumino, R.; Vineis, P.; Bueno-deMesquita, H.B.; Peeters, P.H.; Engeset, D.; Lund E., Skeie G., Ardanaz E., González C., Navarro C., Quirós J.R., Sanchez M.J., Berglund, G.; Mattisson, I.; Hallmans, G.; Palmqvist, R.; Day, N.E.; Khwat, K.T.; Key, T.J.; San Joaquin, M.; Hémon, B.; Saracci, R.; Kaaks, R.; Riboli, E. Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J. Natl. Cancer Inst., 2005, 97(12), 906-16.
    • Norat, T.; Bingham, S.; Ferrari, P.; Sliman, N.; Jenab, M.; Mazuir, M.; Overvad, K.; Olsen, A.; Tjonneland, A.; Clavel, F.; Boutron-Ruault, M.C.; Kesse, E.; Boeing, H.; Bergmann, M.M.; Nieters, A.; Linseisen, J.; Trichopoulou, A.; Trichopoulos, D.; Tountas, Y.; Berrino, F., Palli, D.; Panico, S.; Tumino, R.; Vineis, P.; Bueno-deMesquita, H.B.; Peeters, P.H.; Engeset, D.; Lund E., Skeie G., Ardanaz E., González C., Navarro C., Quirós J.R., Sanchez M.J., Berglund, G.; Mattisson, I.; Hallmans, G.; Palmqvist, R.; Day, N.E.; Khwat, K.T.; Key, T.J.; San Joaquin, M.; Hémon, B.; Saracci, R.; Kaaks, R.; Riboli, E. Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J. Natl. Cancer Inst., 2005, 97(12), 906-16.
  • 4
    • 34250636650 scopus 로고    scopus 로고
    • Colon cancer therapy: New perspectives of nutritional manipulations using polyunsaturated fatty acids
    • Dupertuis, Y.M.; Meguid, M.M.; Pichard, C. Colon cancer therapy: new perspectives of nutritional manipulations using polyunsaturated fatty acids. Curr. Opin. Clin. Nutr. Metab. Care, 2007, 10(4), 427-32.
    • (2007) Curr. Opin. Clin. Nutr. Metab. Care , vol.10 , Issue.4 , pp. 427-432
    • Dupertuis, Y.M.1    Meguid, M.M.2    Pichard, C.3
  • 5
    • 9744228743 scopus 로고    scopus 로고
    • (n-3) fatty acids and cancer therapy
    • Hardman, W.E. (n-3) fatty acids and cancer therapy. J. Nutr., 2004, 134(12 Suppl), 3427S-3430S.
    • (2004) J. Nutr , vol.134 , Issue.12 SUPPL.
    • Hardman, W.E.1
  • 6
    • 1642486753 scopus 로고    scopus 로고
    • n-3 polyunsaturated fatty acids and colon cancer prevention
    • Roynette, C.E.; Calder, P.C.; Dupertuis, Y., M.; Pichard, C. n-3 polyunsaturated fatty acids and colon cancer prevention. Clin. Nutr., 2003, 23(2), 139-51.
    • (2003) Clin. Nutr , vol.23 , Issue.2 , pp. 139-151
    • Roynette, C.E.1    Calder, P.C.2    Dupertuis, Y.M.3    Pichard, C.4
  • 7
    • 0019723809 scopus 로고
    • Accumulation of N-3 polyunsaturated fatty acids cultured human Y79 retinoblastoma cells
    • Hyman, B.T.; Spector, A.A. Accumulation of N-3 polyunsaturated fatty acids cultured human Y79 retinoblastoma cells. J. Neurochem., 1981, 37(1), 60-69.
    • (1981) J. Neurochem , vol.37 , Issue.1 , pp. 60-69
    • Hyman, B.T.1    Spector, A.A.2
  • 8
    • 0014198713 scopus 로고
    • Turnover and utilization of esterified fatty acids in Ehrlich ascites tumor cells
    • Spector, A.A.; Steinberg, D. Turnover and utilization of esterified fatty acids in Ehrlich ascites tumor cells. J. Biol. Chem., 1967, 242(13), 3057-62.
    • (1967) J. Biol. Chem , vol.242 , Issue.13 , pp. 3057-3062
    • Spector, A.A.1    Steinberg, D.2
  • 9
    • 0026465179 scopus 로고
    • Membrane lipid modification and sensitivity of leukemic cells to the thioether lipid analogue BM 41.440
    • Petersen, E.S.; Kelley, E.E.; Modest, E.J.; Burns, C.P. Membrane lipid modification and sensitivity of leukemic cells to the thioether lipid analogue BM 41.440. Cancer Res., 1992, 52(22), 6263-69.
    • (1992) Cancer Res , vol.52 , Issue.22 , pp. 6263-6269
    • Petersen, E.S.1    Kelley, E.E.2    Modest, E.J.3    Burns, C.P.4
  • 10
    • 0023095189 scopus 로고
    • Membrane fatty acid modification in tumor cells: A potential therapeutic adjunct
    • Burns, C.P.; Spector, A.A. Membrane fatty acid modification in tumor cells: a potential therapeutic adjunct. Lipids, 1987, 22(3), 178-84.
    • (1987) Lipids , vol.22 , Issue.3 , pp. 178-184
    • Burns, C.P.1    Spector, A.A.2
  • 11
    • 0030850993 scopus 로고    scopus 로고
    • DHA feeding provides host protection and prevents fibrosarcoma-induced hyperlipidemia while maintaining the tumor response to araC in Fischer 344 rats
    • Atkinson, T.G.; Murray, L.; Berry, D.M.; Rothig, D.J.; Meckling-Gill, K.A. DHA feeding provides host protection and prevents fibrosarcoma-induced hyperlipidemia while maintaining the tumor response to araC in Fischer 344 rats. Nutr. Cancer, 1997, 28(3), 225-35.
    • (1997) Nutr. Cancer , vol.28 , Issue.3 , pp. 225-235
    • Atkinson, T.G.1    Murray, L.2    Berry, D.M.3    Rothig, D.J.4    Meckling-Gill, K.A.5
  • 12
    • 0031000091 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill
    • Vartak, S.; Robbins, M.E.; Spector, A.A. Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill. Lipids, 1997, 32(3), 283-92.
    • (1997) Lipids , vol.32 , Issue.3 , pp. 283-292
    • Vartak, S.1    Robbins, M.E.2    Spector, A.A.3
  • 13
    • 0030762475 scopus 로고    scopus 로고
    • Intervention of transplantable human mammary carcinoma MX-1 chemotherapy with dietary menhaden oil in athymic mice: Increased therapeutic effects and decreased toxicity of cyclophosphamide
    • Shao, Y.; Pardini, L.; Pardini, R.S. Intervention of transplantable human mammary carcinoma MX-1 chemotherapy with dietary menhaden oil in athymic mice: increased therapeutic effects and decreased toxicity of cyclophosphamide. Nutr. Cancer, 1997, 28(1), 63-73.
    • (1997) Nutr. Cancer , vol.28 , Issue.1 , pp. 63-73
    • Shao, Y.1    Pardini, L.2    Pardini, R.S.3
  • 14
    • 24744436204 scopus 로고    scopus 로고
    • Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway
    • Sauer, L.A.; Dauchy, R.T.; Blask, D.E.; Krause, J.A.; Davidson, L.K.; Dauchy, E.M. Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway. J. Nutr., 2005, 135(9), 2124-29.
    • (2005) J. Nutr , vol.135 , Issue.9 , pp. 2124-2129
    • Sauer, L.A.1    Dauchy, R.T.2    Blask, D.E.3    Krause, J.A.4    Davidson, L.K.5    Dauchy, E.M.6
  • 15
    • 0035876962 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, melatonin, and cancer prevention
    • Sauer, L.A.; Dauchy, R.T.; Blask, D.E. Polyunsaturated fatty acids, melatonin, and cancer prevention. Biochem. Pharmacol., 2001, 61(12), 1455-62.
    • (2001) Biochem. Pharmacol , vol.61 , Issue.12 , pp. 1455-1462
    • Sauer, L.A.1    Dauchy, R.T.2    Blask, D.E.3
  • 16
    • 0029803762 scopus 로고    scopus 로고
    • Alteration of n-3 fatty acid composition in lung tissue after short-term infusion of fish oil emulsion attenuates inflammatory vascular reaction
    • Breil, I.; Koch, T.; Heller, A.; Schlotzer, E.; Grunert, A.; van Ackern, K.; Neuhof, H. Alteration of n-3 fatty acid composition in lung tissue after short-term infusion of fish oil emulsion attenuates inflammatory vascular reaction. Crit. Care Med., 1996, 24(11), 1893-902.
    • (1996) Crit. Care Med , vol.24 , Issue.11 , pp. 1893-1902
    • Breil, I.1    Koch, T.2    Heller, A.3    Schlotzer, E.4    Grunert, A.5    van Ackern, K.6    Neuhof, H.7
  • 17
    • 34247847681 scopus 로고    scopus 로고
    • Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways
    • Serhan, C.N. Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu. Rev. Immunol., 2007, 25, 101-37.
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 101-137
    • Serhan, C.N.1
  • 18
    • 33947500462 scopus 로고    scopus 로고
    • Resolvins and protectins in the termination program of acute inflammation
    • Ariel, A.; Serhan, C.N. Resolvins and protectins in the termination program of acute inflammation. Trends Immunol., 2007, 28(4), 176-83.
    • (2007) Trends Immunol , vol.28 , Issue.4 , pp. 176-183
    • Ariel, A.1    Serhan, C.N.2
  • 19
    • 0034916569 scopus 로고    scopus 로고
    • Lipid mediator class switching during acute inflammation: Signals in resolution
    • Levy, B.D.; Clish, C.B.; Schmidt, B.; Gronert, K.; Serhan, C.N. Lipid mediator class switching during acute inflammation: signals in resolution. Nat. Immunol., 2001, 2(7), 612-19.
    • (2001) Nat. Immunol , vol.2 , Issue.7 , pp. 612-619
    • Levy, B.D.1    Clish, C.B.2    Schmidt, B.3    Gronert, K.4    Serhan, C.N.5
  • 20
    • 0034675852 scopus 로고    scopus 로고
    • Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
    • Serhan, C.N.; Clish, C.B.; Brannon, J.; Colgan, S.P.; Chiang, N.; Gronert, K. Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J. Exp. Med., 2000, 192(8), 1197-1204.
    • (2000) J. Exp. Med , vol.192 , Issue.8 , pp. 1197-1204
    • Serhan, C.N.1    Clish, C.B.2    Brannon, J.3    Colgan, S.P.4    Chiang, N.5    Gronert, K.6
  • 21
    • 31144469184 scopus 로고    scopus 로고
    • Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienes
    • Serhan, C.N.; Gotlinger, K.; Hong, S.; Lu, Y.; Siegelman, J.; Baer, T.; Yang, R.; Colgan, S.P.; Petasis, N.A. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J. Immunol., 2006, 176(3), 1848-1859.
    • (2006) J. Immunol , vol.176 , Issue.3 , pp. 1848-1859
    • Serhan, C.N.1    Gotlinger, K.2    Hong, S.3    Lu, Y.4    Siegelman, J.5    Baer, T.6    Yang, R.7    Colgan, S.P.8    Petasis, N.A.9
  • 22
    • 3242797239 scopus 로고    scopus 로고
    • Ohira, T.; Bannenberg, G.; Arita, M.; Takahash,i M.; Ge, Q.; Van Dyke, T.E.; Stahl, G.L.; Serhan, C.N.; Badwey, J.A. A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils. J. Immunol., 2004, 173(3), 2091-98.
    • Ohira, T.; Bannenberg, G.; Arita, M.; Takahash,i M.; Ge, Q.; Van Dyke, T.E.; Stahl, G.L.; Serhan, C.N.; Badwey, J.A. A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils. J. Immunol., 2004, 173(3), 2091-98.
  • 23
    • 0032762407 scopus 로고    scopus 로고
    • Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: Modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions
    • Filep, J.G.; Zouki, C.; Petasis, N.A.; Hachicha, M.; Serhan, C.N. Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions. Blood, 1999, 94(12), 4132-42.
    • (1999) Blood , vol.94 , Issue.12 , pp. 4132-4142
    • Filep, J.G.1    Zouki, C.2    Petasis, N.A.3    Hachicha, M.4    Serhan, C.N.5
  • 24
    • 0034651737 scopus 로고    scopus 로고
    • Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages
    • Godson, C.; Mitchell, S.; Harvey, K.; Petasis, N.A.; Hogg, N.; Brady, H.R. Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J. Immunol., 2000, 164(4),1663-67.
    • (2000) J. Immunol , vol.164 , Issue.4 , pp. 1663-1667
    • Godson, C.1    Mitchell, S.2    Harvey, K.3    Petasis, N.A.4    Hogg, N.5    Brady, H.R.6
  • 25
    • 27544439792 scopus 로고    scopus 로고
    • The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: Novel oxygenase products from omega-3 polyunsaturated fatty acids
    • Arita, M.; Clish, C.B.; Serhan, C.N. The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids. Biochem. Biophys. Res. Commun., 2005, 338(1), 149-57.
    • (2005) Biochem. Biophys. Res. Commun , vol.338 , Issue.1 , pp. 149-157
    • Arita, M.1    Clish, C.B.2    Serhan, C.N.3
  • 26
    • 12344321136 scopus 로고    scopus 로고
    • Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
    • Arita, M.; Bianchini, F.; Aliberti, J.; Sher, A.; Chiang, N.; Hong, S.; Yang, R.; Petasis, N.A.; Serhan, C.N. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J. Exp. Med., 2005, 201(5), 713-22.
    • (2005) J. Exp. Med , vol.201 , Issue.5 , pp. 713-722
    • Arita, M.1    Bianchini, F.2    Aliberti, J.3    Sher, A.4    Chiang, N.5    Hong, S.6    Yang, R.7    Petasis, N.A.8    Serhan, C.N.9
  • 27
    • 33947269798 scopus 로고    scopus 로고
    • Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation
    • Arita, M.; Ohira, T.; Sun, Y.P.; Elangovan, S.; Chiang, N.; Serhan, C.N. Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. J. Immunol., 2007, 178(6), 3912-17.
    • (2007) J. Immunol , vol.178 , Issue.6 , pp. 3912-3917
    • Arita, M.1    Ohira, T.2    Sun, Y.P.3    Elangovan, S.4    Chiang, N.5    Serhan, C.N.6
  • 30
    • 0037152160 scopus 로고    scopus 로고
    • Serhan, C.N.; Hong, S.; Gronert, K.; Colgan, S.P.; Devchand, P.R.; Mirick, G.; Moussignac, R. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med., 2002, 196(8), 1025-37.
    • Serhan, C.N.; Hong, S.; Gronert, K.; Colgan, S.P.; Devchand, P.R.; Mirick, G.; Moussignac, R. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med., 2002, 196(8), 1025-37.
  • 31
    • 0038013967 scopus 로고    scopus 로고
    • Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation
    • Hong S., Gronert K., Devchand P., Moussignac R.-L., Serhan C.N. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J. Biol. Chem., 2003, 278(17), 14677-87.
    • (2003) J. Biol. Chem , vol.278 , Issue.17 , pp. 14677-14687
    • Hong, S.1    Gronert, K.2    Devchand, P.3    Moussignac, R.-L.4    Serhan, C.N.5
  • 33
    • 30044441055 scopus 로고    scopus 로고
    • The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering
    • Ariel, A.; Li, P.L.; Wang, W.; Tang, W.X.; Fredman, G.; Hong, S.; Gotlinger, K.H.; Serhan, C.N. The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering. J. Biol. Chem., 2005, 280(52), 43079-86.
    • (2005) J. Biol. Chem , vol.280 , Issue.52 , pp. 43079-43086
    • Ariel, A.1    Li, P.L.2    Wang, W.3    Tang, W.X.4    Fredman, G.5    Hong, S.6    Gotlinger, K.H.7    Serhan, C.N.8
  • 35
    • 33750112087 scopus 로고    scopus 로고
    • Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
    • Ariel, A.; Fredman, G.; Sun, Y.P.; Kantarci, A.; Van Dyke, T.E.; Luster, A.D.; Serhan, C.N. Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nat. Immunol., 2006, 7(11), 1209-16.
    • (2006) Nat. Immunol , vol.7 , Issue.11 , pp. 1209-1216
    • Ariel, A.1    Fredman, G.2    Sun, Y.P.3    Kantarci, A.4    Van Dyke, T.E.5    Luster, A.D.6    Serhan, C.N.7
  • 38
    • 3242755102 scopus 로고    scopus 로고
    • Molecular biology of sporadic gastric cancer: Prognostic indicators and novel therapeutic approaches
    • Scartozzi, M.; Galizia, E.; Freddari, F.; Berardi, R.; Cellerino, R.; Cascinu, S. Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches. Cancer Treat. Rev., 2004, 30(5), 451-59.
    • (2004) Cancer Treat. Rev , vol.30 , Issue.5 , pp. 451-459
    • Scartozzi, M.1    Galizia, E.2    Freddari, F.3    Berardi, R.4    Cellerino, R.5    Cascinu, S.6
  • 40
    • 0034994904 scopus 로고    scopus 로고
    • Association of enhanced cyclooxygenase-2 expression with possible local immunosuppression in human colorectal carcinomas
    • Kojima, M.; Morisaki, T.; Uchiyama, A.; Doi, F.; Mibu, R.; Katano, M.; Tanaka, M. Association of enhanced cyclooxygenase-2 expression with possible local immunosuppression in human colorectal carcinomas. Ann. Surg. Oncol., 2001, 8(5), 458-65.
    • (2001) Ann. Surg. Oncol , vol.8 , Issue.5 , pp. 458-465
    • Kojima, M.1    Morisaki, T.2    Uchiyama, A.3    Doi, F.4    Mibu, R.5    Katano, M.6    Tanaka, M.7
  • 42
    • 0029008617 scopus 로고
    • Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
    • Kargman, S.; O'Neill, G.; Vickers, P.; Evans, J.; Mancini, J.; Jothy, S. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res., 1995, 55(12), 2556-59.
    • (1995) Cancer Res , vol.55 , Issue.12 , pp. 2556-2559
    • Kargman, S.1    O'Neill, G.2    Vickers, P.3    Evans, J.4    Mancini, J.5    Jothy, S.6
  • 45
    • 0037824479 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and -2 associated with expression of VEGF in primary cervical cancer and at metastatic lymph nodes
    • Kim, M.H.; Seo, S.S.; Song, Y.S.; Kang, D.H.; Park, I.A.; Kang, S.B.; Lee, HP. Expression of cyclooxygenase-1 and -2 associated with expression of VEGF in primary cervical cancer and at metastatic lymph nodes. Gynecol. Oncol., 2003, 90(1), 83-90.
    • (2003) Gynecol. Oncol , vol.90 , Issue.1 , pp. 83-90
    • Kim, M.H.1    Seo, S.S.2    Song, Y.S.3    Kang, D.H.4    Park, I.A.5    Kang, S.B.6    Lee, H.P.7
  • 49
    • 0035863223 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors
    • Kokawa, A.; Kondo, H.; Gotoda, T.; Ono, H.; Saito, D.; Nakadaira, S.; Kosuge, T.; Yoshida, S. Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors. Cancer (Phila.), 2001, 91(2), 333-38.
    • (2001) Cancer (Phila.) , vol.91 , Issue.2 , pp. 333-338
    • Kokawa, A.1    Kondo, H.2    Gotoda, T.3    Ono, H.4    Saito, D.5    Nakadaira, S.6    Kosuge, T.7    Yoshida, S.8
  • 55
    • 0038489501 scopus 로고    scopus 로고
    • Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer
    • Chu, J.; Lloyd, F.; Trifan, O.C.; Knapp, B.; Rizzo, M.T. Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer. Mol. Cancer Ther., 2003, 2(1), 1-7.
    • (2003) Mol. Cancer Ther , vol.2 , Issue.1 , pp. 1-7
    • Chu, J.1    Lloyd, F.2    Trifan, O.C.3    Knapp, B.4    Rizzo, M.T.5
  • 57
    • 36849059146 scopus 로고    scopus 로고
    • Repasky, G.A.; Zhou, Y.; Morita, S.; Der, C.J. Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling. Mol. Carcinogen., 2007, 46(12), 958-70.
    • Repasky, G.A.; Zhou, Y.; Morita, S.; Der, C.J. Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling. Mol. Carcinogen., 2007, 46(12), 958-70.
  • 58
    • 10344263374 scopus 로고    scopus 로고
    • Palozza, P. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway
    • Calviello, G.; Di Nicuolo, F.; Gragnoli, S.; Piccioni, E.; Serini, S.; Maggiano, N.; Tringali, G.; Navarra, P.; Ranelletti, F.O.; Palozza, P. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway. Carcinogenesis, 2004, 25(12), 2303-10.
    • (2004) Carcinogenesis , vol.25 , Issue.12 , pp. 2303-2310
    • Calviello, G.1    Di Nicuolo, F.2    Gragnoli, S.3    Piccioni, E.4    Serini, S.5    Maggiano, N.6    Tringali, G.7    Navarra, P.8    Ranelletti, F.O.9
  • 59
    • 0037146555 scopus 로고    scopus 로고
    • Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line
    • Liu, X.; Kirschenbaum, A.; Lu, M.; Yao, S.; Dosoretz, A.; Holland, J.F.; Levine, A.C. Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. J. Biol. Chem., 2002, 277(51), 50081-86.
    • (2002) J. Biol. Chem , vol.277 , Issue.51 , pp. 50081-50086
    • Liu, X.1    Kirschenbaum, A.2    Lu, M.3    Yao, S.4    Dosoretz, A.5    Holland, J.F.6    Levine, A.C.7
  • 60
    • 35848955898 scopus 로고    scopus 로고
    • Prostaglandin E2 induces vascular endothelial growth factor secretion in prostate cancer cells through EP2 receptor-mediated cAMP pathway
    • Wang, X.; Klein, R.D. Prostaglandin E2 induces vascular endothelial growth factor secretion in prostate cancer cells through EP2 receptor-mediated cAMP pathway. Mol. Carcinogen., 2007, 46(11), 912-23.
    • (2007) Mol. Carcinogen , vol.46 , Issue.11 , pp. 912-923
    • Wang, X.1    Klein, R.D.2
  • 61
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Takahashi, Y.; Kitaday, Y.; Bucana, C.D.; Cleary, K.R.; Ellis, L.M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res., 1995, 55(18), 3964-3968.
    • (1995) Cancer Res , vol.55 , Issue.18 , pp. 3964-3968
    • Takahashi, Y.1    Kitaday, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 62
    • 0033010512 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is up-regulated in the early pre-malignant stage of colorectal tumour progression
    • Wong, M.P.; Cheung, N.; Yuen, S.T.; Leung, S.Y.; Chung, L.P. Vascular endothelial growth factor is up-regulated in the early pre-malignant stage of colorectal tumour progression. Int. J. Cancer, 1999, 81(6), 845-850.
    • (1999) Int. J. Cancer , vol.81 , Issue.6 , pp. 845-850
    • Wong, M.P.1    Cheung, N.2    Yuen, S.T.3    Leung, S.Y.4    Chung, L.P.5
  • 64
    • 27644543263 scopus 로고    scopus 로고
    • Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2
    • Sinicrope, F.A.; Penington, R.C. Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2. Mol. Cancer Ther., 2005, 4(10), 1475-83.
    • (2005) Mol. Cancer Ther , vol.4 , Issue.10 , pp. 1475-1483
    • Sinicrope, F.A.1    Penington, R.C.2
  • 66
    • 1842790624 scopus 로고    scopus 로고
    • Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells
    • Shao, J.; Evers, B.M.; Sheng, H. Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells. J. Biol. Chem., 2004, 279(14), 14287-93.
    • (2004) J. Biol. Chem , vol.279 , Issue.14 , pp. 14287-14293
    • Shao, J.1    Evers, B.M.2    Sheng, H.3
  • 67
    • 0026726738 scopus 로고
    • Dietary fat and colon cancer: Animal model studies
    • Reddy, B.S. Dietary fat and colon cancer: animal model studies. Lipids, 1992, 27(10), 802-813.
    • (1992) Lipids , vol.27 , Issue.10 , pp. 802-813
    • Reddy, B.S.1
  • 68
    • 0022637661 scopus 로고
    • Effect of dietary fish oil on azoxymethane-induced colon carcinogenesis in male F344 rats
    • Reddy, B.S.; Maruyama, H. Effect of dietary fish oil on azoxymethane-induced colon carcinogenesis in male F344 rats. Cancer Res., 1986, 46(7), 3367-70.
    • (1986) Cancer Res , vol.46 , Issue.7 , pp. 3367-3370
    • Reddy, B.S.1    Maruyama, H.2
  • 69
    • 0026023962 scopus 로고
    • Effect of diets high in omega-3 and omega-6 fatty acids on initiation and postinitiation stages of colon carcinogenesis
    • Reddy, B.S.; Sugie, S. Effect of diets high in omega-3 and omega-6 fatty acids on initiation and postinitiation stages of colon carcinogenesis. Cancer Res., 1991, 51(2), 487-91.
    • (1991) Cancer Res , vol.51 , Issue.2 , pp. 487-491
    • Reddy, B.S.1    Sugie, S.2
  • 70
    • 0025644569 scopus 로고
    • The effect of dietary omega-3 fatty acids (fish oil) on azoxymethanol-induced focal areas of dysplasia and colon tumor incidence
    • Deschner, E.E.; Lytle, J.S.; Wong, G.; Ruperto, J.D.; Newmark, H.L. The effect of dietary omega-3 fatty acids (fish oil) on azoxymethanol-induced focal areas of dysplasia and colon tumor incidence. Cancer (Phila), 1990, 66(11), 2350-56.
    • (1990) Cancer (Phila) , vol.66 , Issue.11 , pp. 2350-2356
    • Deschner, E.E.1    Lytle, J.S.2    Wong, G.3    Ruperto, J.D.4    Newmark, H.L.5
  • 71
    • 0034101687 scopus 로고    scopus 로고
    • Modulation of murine mammary tumor vasculature by dietary n-3 fatty acids in fish oil
    • Mukutmoni-Norris, M.; Hubbard, N.E.; and Erickson, K.L. Modulation of murine mammary tumor vasculature by dietary n-3 fatty acids in fish oil. Cancer Lett., 2000, 150(1), 101-109.
    • (2000) Cancer Lett , vol.150 , Issue.1 , pp. 101-109
    • Mukutmoni-Norris, M.1    Hubbard, N.E.2    Erickson, K.L.3
  • 72
    • 0033228435 scopus 로고    scopus 로고
    • Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice
    • Rose, D.P.; Connolly, J.M. Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice. Int. J. Oncol., 1999, 15(5), 1011-1015.
    • (1999) Int. J. Oncol , vol.15 , Issue.5 , pp. 1011-1015
    • Rose, D.P.1    Connolly, J.M.2
  • 76
    • 0344406231 scopus 로고    scopus 로고
    • The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines
    • Dommels, Y.E.; Haring, M.M.G.; Keestra, N.G.M.; Alink, G.M.; van Bladeren, P.J.; van Ommen, B. The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines. Carcinogenesis, 2003, 24(3), 385-92.
    • (2003) Carcinogenesis , vol.24 , Issue.3 , pp. 385-392
    • Dommels, Y.E.1    Haring, M.M.G.2    Keestra, N.G.M.3    Alink, G.M.4    van Bladeren, P.J.5    van Ommen, B.6
  • 77
    • 0035866384 scopus 로고    scopus 로고
    • Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: Mediation through cyclooxygenase-independent pathways
    • Boudreau, M.D.; Sohn, K.H.; Rhee, S.H.; Lee, S.W.; Hunt, J.D.; Hwang, D.H. Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways. Cancer Res., 2001, 61(4), 1386-91.
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1386-1391
    • Boudreau, M.D.1    Sohn, K.H.2    Rhee, S.H.3    Lee, S.W.4    Hunt, J.D.5    Hwang, D.H.6
  • 78
    • 24944493352 scopus 로고    scopus 로고
    • Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma
    • Denkins, Y.; Kempf, D.; Ferniz, M.; Nileshwar, S.; Marchetti, D. Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma. J. Lipid Res., 2005, 46(6), 1278-84.
    • (2005) J. Lipid Res , vol.46 , Issue.6 , pp. 1278-1284
    • Denkins, Y.1    Kempf, D.2    Ferniz, M.3    Nileshwar, S.4    Marchetti, D.5
  • 79
    • 33744984596 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 for prevention and therapy of colorectal cancer
    • Sinicrope, F.A. Targeting cyclooxygenase-2 for prevention and therapy of colorectal cancer. Mol. Carcinogen., 2006, 45(6), 447-54.
    • (2006) Mol. Carcinogen , vol.45 , Issue.6 , pp. 447-454
    • Sinicrope, F.A.1
  • 81
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • He, T.C.; Chan, T.A.; Vogelstein, B.; Kinzler, K.W. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell, 1999, 99(3), 335-45.
    • (1999) Cell , vol.99 , Issue.3 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 82
    • 0034700110 scopus 로고    scopus 로고
    • Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
    • Gupta, R.A.; Tan, J.; Krause, W.F.; Geraci, M.W.; Wilson, T.M.; Dey, S.K.; DuBois, R.N. Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc. Natl. Acad. Sci. USA, 2000, 97(24), 13275-80.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.24 , pp. 13275-13280
    • Gupta, R.A.1    Tan, J.2    Krause, W.F.3    Geraci, M.W.4    Wilson, T.M.5    Dey, S.K.6    DuBois, R.N.7
  • 83
    • 0035956850 scopus 로고    scopus 로고
    • Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
    • Park, B.H.; Vogelstein, B.; Kinzler, W. Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc. Natl. Acad. Sci. USA, 2001, 98(5), 2598-2603.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.5 , pp. 2598-2603
    • Park, B.H.1    Vogelstein, B.2    Kinzler, W.3
  • 84
    • 1942470331 scopus 로고    scopus 로고
    • Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
    • Gupta, R.A.; Wang, D.; Katkuri, S.; Wang, H.; Dey, S.K.; DuBois, R.N. Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat. Med., 2004, 10(3), 245-47.
    • (2004) Nat. Med , vol.10 , Issue.3 , pp. 245-247
    • Gupta, R.A.1    Wang, D.2    Katkuri, S.3    Wang, H.4    Dey, S.K.5    DuBois, R.N.6
  • 90
    • 2442708845 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis
    • Harman, F.S.; Nicol, C.J.; Marin, H.E.; Ward, J.M.; Gonzalez, F.J.; Peters, J.M. Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis. Nat. Med., 2004, 10(5), 481-83.
    • (2004) Nat. Med , vol.10 , Issue.5 , pp. 481-483
    • Harman, F.S.1    Nicol, C.J.2    Marin, H.E.3    Ward, J.M.4    Gonzalez, F.J.5    Peters, J.M.6
  • 91
  • 92
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
    • Lefebvre, A.M.; Chen, I.; Desreumaux, P.; Najib, J.; Fruchart, J.C.; Geboes, K.; Briggs, M.; Heyman, R.; Auwerx, J. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. Nat. Med., 1998, 4(9), 1053-57.
    • (1998) Nat. Med , vol.4 , Issue.9 , pp. 1053-1057
    • Lefebvre, A.M.1    Chen, I.2    Desreumaux, P.3    Najib, J.4    Fruchart, J.C.5    Geboes, K.6    Briggs, M.7    Heyman, R.8    Auwerx, J.9
  • 95
    • 0030612740 scopus 로고    scopus 로고
    • PPARgamma induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A
    • Altiok, S.; Xu, M.; Spiegelman, B.M. PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev., 1997, 11(15), 1987-98.
    • (1997) Genes Dev , vol.11 , Issue.15 , pp. 1987-1998
    • Altiok, S.1    Xu, M.2    Spiegelman, B.M.3
  • 96
    • 0030831977 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor gamma, CCAAT/enhancer-binding protein alpha, and cell cycle status regulate the commitment to adipocyte differentiation
    • Shao, D.; Lazar, M.A. Peroxisome proliferator activated receptor gamma, CCAAT/enhancer-binding protein alpha, and cell cycle status regulate the commitment to adipocyte differentiation. J. Biol. Chem., 1997, 272(34), 21473-478.
    • (1997) J. Biol. Chem , vol.272 , Issue.34 , pp. 21473-21478
    • Shao, D.1    Lazar, M.A.2
  • 97
    • 0033546003 scopus 로고    scopus 로고
    • Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c) and p21(Waf1/Cip1), during adipogenesis
    • Morrison, R.F.; Farmer, S.R. Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c) and p21(Waf1/Cip1), during adipogenesis. J. Biol. Chem., 1999, 274(24), 17088-97.
    • (1999) J. Biol. Chem , vol.274 , Issue.24 , pp. 17088-17097
    • Morrison, R.F.1    Farmer, S.R.2
  • 98
    • 1642381346 scopus 로고    scopus 로고
    • Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells
    • Han, S.; Sidell, N.; Fisher, P.B.; Roman, J. Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells. Clin. Cancer Res., 2004, 10(6), 1911-19.
    • (2004) Clin. Cancer Res , vol.10 , Issue.6 , pp. 1911-1919
    • Han, S.1    Sidell, N.2    Fisher, P.B.3    Roman, J.4
  • 99
    • 0035094340 scopus 로고    scopus 로고
    • The pleiotropic functions of peroxisome proliferator-activated receptor gamma
    • Debril, M.B.; Renaud, J.P.; Fajas, L.; Auwerx, J. The pleiotropic functions of peroxisome proliferator-activated receptor gamma. J. Mol. Med., 2001, 79(1), 30-47.
    • (2001) J. Mol. Med , vol.79 , Issue.1 , pp. 30-47
    • Debril, M.B.1    Renaud, J.P.2    Fajas, L.3    Auwerx, J.4
  • 103
    • 1942471942 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-gamma (PPAR-gamma) ligands and angiogenesis
    • Margeli, A.; Kouraklis, G.; Theocharis, S. Peroxisome proliferator activated receptor-gamma (PPAR-gamma) ligands and angiogenesis. Angiogenesis, 2003, 6(3), 165-69.
    • (2003) Angiogenesis , vol.6 , Issue.3 , pp. 165-169
    • Margeli, A.1    Kouraklis, G.2    Theocharis, S.3
  • 104
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin, X.; Yang, S.; Kowalski, J.; Gerritsen, M.E. Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J. Biol. Chem., 1999, 274(13), 9116-21.
    • (1999) J. Biol. Chem , vol.274 , Issue.13 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 106
    • 0033206336 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death
    • Guan, Y.F.; Zhang, Y.H.; Breyer, R.M.; Davis, L.; Breyer, M.D. Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death. Neoplasia, 1999, 1(4), 330-39.
    • (1999) Neoplasia , vol.1 , Issue.4 , pp. 330-339
    • Guan, Y.F.1    Zhang, Y.H.2    Breyer, R.M.3    Davis, L.4    Breyer, M.D.5
  • 107
    • 0037189578 scopus 로고    scopus 로고
    • Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells
    • Fauconnet, S.; Lascombe, I.; Chabannes, E.; Adessi, G.L.; Desvergene, B.; Wahli, W.; Bittard, H. Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells. J. Biol. Chem., 2002, 277(26), 23534-43.
    • (2002) J. Biol. Chem , vol.277 , Issue.26 , pp. 23534-23543
    • Fauconnet, S.1    Lascombe, I.2    Chabannes, E.3    Adessi, G.L.4    Desvergene, B.5    Wahli, W.6    Bittard, H.7
  • 111
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti, G.; Fruchart, J.C.; Sstaels, B. Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm. Res., 2000, 49(10), 497-505.
    • (2000) Inflamm. Res , vol.49 , Issue.10 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Sstaels, B.3
  • 112
    • 0030200209 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Sethi, S.; Eastman, A.Y.; Eaton, J.W. Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. J. Lab. Clin. Med., 1996, 128(1), 27-38.
    • (1996) J. Lab. Clin. Med , vol.128 , Issue.1 , pp. 27-38
    • Sethi, S.1    Eastman, A.Y.2    Eaton, J.W.3
  • 113
    • 4444363663 scopus 로고    scopus 로고
    • Oxidized omega-3 fatty acids inhibit pro-inflammatory responses in glomerular endothelial cells
    • Chaudhary, A.; Mishra, A.; Sethi, S. Oxidized omega-3 fatty acids inhibit pro-inflammatory responses in glomerular endothelial cells. Nephron. Exp. Nephrol., 2004, 97(4), e136-e145.
    • (2004) Nephron. Exp. Nephrol , vol.97 , Issue.4
    • Chaudhary, A.1    Mishra, A.2    Sethi, S.3
  • 114
    • 20844440063 scopus 로고    scopus 로고
    • EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-gamma-dependent mechanism
    • Li, H.; Ruan, X.Z.; Powis, S.H.; Fernando, R.; Mon, W.Y.; Wheeler, D.C.; Moorhead, J.F.; Varghese, Z. EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: evidence for a PPAR-gamma-dependent mechanism. Kidney Int., 2005, 67(3), 867-74.
    • (2005) Kidney Int , vol.67 , Issue.3 , pp. 867-874
    • Li, H.1    Ruan, X.Z.2    Powis, S.H.3    Fernando, R.4    Mon, W.Y.5    Wheeler, D.C.6    Moorhead, J.F.7    Varghese, Z.8
  • 115
    • 33645742148 scopus 로고    scopus 로고
    • N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways
    • Abedin, M.; Lim, J.; Tang, T.B.; Park, D.; Demer, L.L.; Tintut, Y. N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways. Circ. Res., 2006, 98(6), 727-29.
    • (2006) Circ. Res , vol.98 , Issue.6 , pp. 727-729
    • Abedin, M.1    Lim, J.2    Tang, T.B.3    Park, D.4    Demer, L.L.5    Tintut, Y.6
  • 116
    • 38949108301 scopus 로고    scopus 로고
    • PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells
    • Allred, C.D.; Talbert, D.R.; Southard, R.C.; Wang, X.; Kilgore, M.W. PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells. J. Nutr., 2008, 138(2), 250-56.
    • (2008) J. Nutr , vol.138 , Issue.2 , pp. 250-256
    • Allred, C.D.1    Talbert, D.R.2    Southard, R.C.3    Wang, X.4    Kilgore, M.W.5
  • 117
    • 33747860915 scopus 로고    scopus 로고
    • Troglitazone and 9cis,11trans,13trans-conjugated linolenic acid: Comparison of their antiproliferative and apoptosis-inducing effects on different colon cancer cell lines
    • Yasui, Y.; Hosokawa, M.; Kohno, H.; Tanaka, T.; Miyashita, K. Troglitazone and 9cis,11trans,13trans-conjugated linolenic acid: comparison of their antiproliferative and apoptosis-inducing effects on different colon cancer cell lines. Chemotherapy, 2006, 52(5), 220-25.
    • (2006) Chemotherapy , vol.52 , Issue.5 , pp. 220-225
    • Yasui, Y.1    Hosokawa, M.2    Kohno, H.3    Tanaka, T.4    Miyashita, K.5
  • 118
    • 0036432889 scopus 로고    scopus 로고
    • Docosahexaenoic acid suppresses the activity of peroxisome proliferator-activated receptors in a colon tumor cell line
    • Lee, J.Y.; Hwang, D.H. Docosahexaenoic acid suppresses the activity of peroxisome proliferator-activated receptors in a colon tumor cell line. Biochem. Biophys. Res. Commun., 2002, 298(5), 667-74.
    • (2002) Biochem. Biophys. Res. Commun , vol.298 , Issue.5 , pp. 667-674
    • Lee, J.Y.1    Hwang, D.H.2
  • 120
    • 0025260126 scopus 로고
    • Incorporation of marine lipids into mitochondrial membranes increases susceptibility to damage by calcium and reactive oxygen species: Evidence for enhanced activation of phospholipase A2 in mitochondria enriched with n-3 fatty acids
    • Malis, C.D.; Weber, P.C.; Leaf, A.; Bonventre, J.V. Incorporation of marine lipids into mitochondrial membranes increases susceptibility to damage by calcium and reactive oxygen species: evidence for enhanced activation of phospholipase A2 in mitochondria enriched with n-3 fatty acids. Proc. Natl Acad. Sci. USA, 1990, 87(22), 8845-8849.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , Issue.22 , pp. 8845-8849
    • Malis, C.D.1    Weber, P.C.2    Leaf, A.3    Bonventre, J.V.4
  • 123
    • 10044256699 scopus 로고    scopus 로고
    • An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis
    • Sanders, L.M.; Henderson, C.E.; Hong, M.Y.; Barhoumi, R.; Burghardt, R.C.; Wang, N.; Spinka, C.M.; Carroll, R.J.; Turner, N.D.; Chapkin, R.S.; Lupton J.R. An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis. J. Nutr., 2004, 134(12), 3233-3238.
    • (2004) J. Nutr , vol.134 , Issue.12 , pp. 3233-3238
    • Sanders, L.M.1    Henderson, C.E.2    Hong, M.Y.3    Barhoumi, R.4    Burghardt, R.C.5    Wang, N.6    Spinka, C.M.7    Carroll, R.J.8    Turner, N.D.9    Chapkin, R.S.10    Lupton, J.R.11
  • 124
    • 0034643267 scopus 로고    scopus 로고
    • Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells?
    • Igarashi M.; Miyazawa, T. Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells? Biochem. Biophys. Res. Commun., 2000, 270(2), 649-656.
    • (2000) Biochem. Biophys. Res. Commun , vol.270 , Issue.2 , pp. 649-656
    • Igarashi, M.1    Miyazawa, T.2
  • 125
    • 2442508116 scopus 로고    scopus 로고
    • Conjugated eicosapentaenoic acid (EPA) inhibits transplanted tumor growth via membrane lipid peroxidation in nude mice
    • Tsuzuki, T.; Igarashi, M.; Miyazawa, T. Conjugated eicosapentaenoic acid (EPA) inhibits transplanted tumor growth via membrane lipid peroxidation in nude mice. J. Nutr., 2004, 134(5), 1162-1166.
    • (2004) J. Nutr , vol.134 , Issue.5 , pp. 1162-1166
    • Tsuzuki, T.1    Igarashi, M.2    Miyazawa, T.3
  • 126
    • 0033639198 scopus 로고    scopus 로고
    • Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells
    • Chen, Z.Y.; Istfan, N.W. Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. Prostaglandins Leukot. Essent. Fatty Acids, 2000, 63(5), 301-308.
    • (2000) Prostaglandins Leukot. Essent. Fatty Acids , vol.63 , Issue.5 , pp. 301-308
    • Chen, Z.Y.1    Istfan, N.W.2
  • 127
    • 0034962169 scopus 로고    scopus 로고
    • Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo
    • Latham, P.; Lund, E.K.; Brown, J.C.; Johnson, I.T. Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo. Gut, 2001, 49(1), 97-105.
    • (2001) Gut , vol.49 , Issue.1 , pp. 97-105
    • Latham, P.1    Lund, E.K.2    Brown, J.C.3    Johnson, I.T.4
  • 128
    • 34347251597 scopus 로고    scopus 로고
    • Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation
    • Kolar, S.S.N.; Barhoumi, R.; Lupton, J.R.; Chapkin, R.S. Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation. Cancer Res., 2007, 67(11), 5561-8.
    • (2007) Cancer Res , vol.67 , Issue.11 , pp. 5561-5568
    • Kolar, S.S.N.1    Barhoumi, R.2    Lupton, J.R.3    Chapkin, R.S.4
  • 129
    • 0033805442 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis
    • Kannan, K.; Jain, S.K. Oxidative stress and apoptosis. Pathophysiology, 2000, 7(3), 153-163.
    • (2000) Pathophysiology , vol.7 , Issue.3 , pp. 153-163
    • Kannan, K.1    Jain, S.K.2
  • 130
    • 0842346433 scopus 로고    scopus 로고
    • Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy
    • Chastel, C.; Jiricny, J.; Jaussi, R. Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy. DNA Repair, 2004, 3(3), 201-215.
    • (2004) DNA Repair , vol.3 , Issue.3 , pp. 201-215
    • Chastel, C.1    Jiricny, J.2    Jaussi, R.3
  • 132
    • 33846045643 scopus 로고    scopus 로고
    • Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells
    • Tsuzuki, T.; Kambe, T.; Shibata, A.; Kawakami, Y.; Nakagawa, K.; Miyazawa, T. Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells. Biochim. Biophys. Acta, 2007, 1771(1), 20-30.
    • (2007) Biochim. Biophys. Acta , vol.1771 , Issue.1 , pp. 20-30
    • Tsuzuki, T.1    Kambe, T.2    Shibata, A.3    Kawakami, Y.4    Nakagawa, K.5    Miyazawa, T.6
  • 133
    • 33747508118 scopus 로고    scopus 로고
    • Docosahexaenoic acid in combination with celecoxib modulates HSP70 and p53 proteins in prostate cancer cells
    • Narayanan, N.K.; Narayanan, B.A.; Bosland, M.; Condin, M.; Nargi, D. Docosahexaenoic acid in combination with celecoxib modulates HSP70 and p53 proteins in prostate cancer cells. Int. J. Cancer, 2006, 119(7), 1586-1598.
    • (2006) Int. J. Cancer , vol.119 , Issue.7 , pp. 1586-1598
    • Narayanan, N.K.1    Narayanan, B.A.2    Bosland, M.3    Condin, M.4    Nargi, D.5
  • 134
    • 36148957839 scopus 로고    scopus 로고
    • Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes
    • Kolar, S.; Barhoumi, R.; Callaway, E.S.; Fan, Y.Y.; Wang, N.; Lupton, J.R.; Chapkin, R.S. Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes. Am. J. Physiol. Gastrointest. Liver Physiol., 2007, 293(5), G935-43.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol , vol.293 , Issue.5
    • Kolar, S.1    Barhoumi, R.2    Callaway, E.S.3    Fan, Y.Y.4    Wang, N.5    Lupton, J.R.6    Chapkin, R.S.7
  • 136
    • 21344432832 scopus 로고    scopus 로고
    • Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation
    • Yonezawa, Y.; Hada, T.; Uryu, K.; Tsuzuki, T.; Eitsuka, T.; Miyazawa, T.; Murakami-Nakai, C.; Yoshida, H.; Mizushina, Y. Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation. Biochem. Pharmacol., 2005, 70(3), 453-460.
    • (2005) Biochem. Pharmacol , vol.70 , Issue.3 , pp. 453-460
    • Yonezawa, Y.1    Hada, T.2    Uryu, K.3    Tsuzuki, T.4    Eitsuka, T.5    Miyazawa, T.6    Murakami-Nakai, C.7    Yoshida, H.8    Mizushina, Y.9
  • 137
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • Nicholson, K.M.; Anderson, N.G. The protein kinase B/Akt signalling pathway in human malignancy. Cell. Signal., 2002, 14(5), 381-395.
    • (2002) Cell. Signal , vol.14 , Issue.5 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 138
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl, H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene, 1999, 18(49), 6853-66.
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6853-6866
    • Pahl, H.L.1
  • 139
    • 0036633164 scopus 로고    scopus 로고
    • Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
    • Clark, A.S.; West, K.; Streicher, S.; Denis, P.A. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol. Cancer Ther., 2002, 1(9), 707-17.
    • (2002) Mol. Cancer Ther , vol.1 , Issue.9 , pp. 707-717
    • Clark, A.S.1    West, K.2    Streicher, S.3    Denis, P.A.4
  • 140
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
    • Campbell, R.A.; Bhat-Nakshatri, P.; Patel, N.M. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J. Biol. Chem., 2001, 276(13), 9817-24.
    • (2001) J. Biol. Chem , vol.276 , Issue.13 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3
  • 143
    • 0035147380 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acid supplementation alters inositol phosphate metabolism and protein kinase C activity in adult porcine cardiac myocytes
    • Nair, S.S.; Letich, J.; Garg, L.M. N-3 polyunsaturated fatty acid supplementation alters inositol phosphate metabolism and protein kinase C activity in adult porcine cardiac myocytes. J. Nutr. Biochem., 2001, 12(1), 7-13.
    • (2001) J. Nutr. Biochem , vol.12 , Issue.1 , pp. 7-13
    • Nair, S.S.1    Letich, J.2    Garg, L.M.3
  • 144
    • 0033866819 scopus 로고    scopus 로고
    • Morphodensitometric analysis of protein kinase C beta(II) expression in rat colon: Modulation by diet and relation to in situ cell proliferation and apoptosis
    • Davidson, L.A.; Brown, R.E.; Chang, W.C.; Morris, J.S.; Wang, N.; Caroll, R.J.; Turner, N.D.; Lupton, J.R.; Chapkin, R.S. Morphodensitometric analysis of protein kinase C beta(II) expression in rat colon: modulation by diet and relation to in situ cell proliferation and apoptosis. Carcinogenesis, 2000, 21(8), 1513-19.
    • (2000) Carcinogenesis , vol.21 , Issue.8 , pp. 1513-1519
    • Davidson, L.A.1    Brown, R.E.2    Chang, W.C.3    Morris, J.S.4    Wang, N.5    Caroll, R.J.6    Turner, N.D.7    Lupton, J.R.8    Chapkin, R.S.9
  • 145
    • 21644462730 scopus 로고    scopus 로고
    • Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells
    • Schley, P.D.; Jijon, H.B.; Robinson, L.E.; Catherine, J.; Field, C.J. Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells. Breast Cancer Res. Treat., 2005, 92(2), 187-195
    • (2005) Breast Cancer Res. Treat , vol.92 , Issue.2 , pp. 187-195
    • Schley, P.D.1    Jijon, H.B.2    Robinson, L.E.3    Catherine, J.4    Field, C.J.5
  • 146
    • 0030927167 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth
    • Nakshatri, H.; Bhat-Nakshatri, P.; Martin, D.A.; Goulet, R.J. Jr; Sledge, G.W. Jr. Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth. Mol. Cell. Biol., 1997, 17(7), 3629-3639.
    • (1997) Mol. Cell. Biol , vol.17 , Issue.7 , pp. 3629-3639
    • Nakshatri, H.1    Bhat-Nakshatri, P.2    Martin, D.A.3    Goulet Jr, R.J.4    Sledge Jr., G.W.5
  • 147
    • 3242687235 scopus 로고    scopus 로고
    • Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer
    • Camp, E.R.; Li, J.; Minnich, D.J.; Brank, A.; Moldawer, L.L.; MacKay, S.L.D.; Hochwald, S.N. Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer. J. Am. Coll. Surg., 2004, 199(2), 249-258.
    • (2004) J. Am. Coll. Surg , vol.199 , Issue.2 , pp. 249-258
    • Camp, E.R.1    Li, J.2    Minnich, D.J.3    Brank, A.4    Moldawer, L.L.5    MacKay, S.L.D.6    Hochwald, S.N.7
  • 148
    • 0034192390 scopus 로고    scopus 로고
    • Cusack, J.C. Jr.; Liu, R.; Baldwin, A.S. Jr. Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation. Cancer Res., 2000, 60(9), 2323-2330.
    • Cusack, J.C. Jr.; Liu, R.; Baldwin, A.S. Jr. Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation. Cancer Res., 2000, 60(9), 2323-2330.
  • 149
    • 33646011538 scopus 로고    scopus 로고
    • Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kappaB
    • Li, J.; Minnich, D.J.; Camp, E.R.; Brank, A.; MacKay, S.L.D.; Hochwald, S.N. Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kappaB. J. Surg. Res., 2006, 132(1), 112-120.
    • (2006) J. Surg. Res , vol.132 , Issue.1 , pp. 112-120
    • Li, J.1    Minnich, D.J.2    Camp, E.R.3    Brank, A.4    MacKay, S.L.D.5    Hochwald, S.N.6
  • 152
    • 0036483890 scopus 로고    scopus 로고
    • Potentiation of tumor necrosis factor-mediated apoptosis of oral squamous cell carcinoma cells by adenovirus-mediated gene transfer of NF-kappaB inhibitor
    • Chen, S.; Fribley, A.; Wang, C.-Y. Potentiation of tumor necrosis factor-mediated apoptosis of oral squamous cell carcinoma cells by adenovirus-mediated gene transfer of NF-kappaB inhibitor. J. Dent. Res., 2002, 81(2), 98-102.
    • (2002) J. Dent. Res , vol.81 , Issue.2 , pp. 98-102
    • Chen, S.1    Fribley, A.2    Wang, C.-Y.3
  • 153
    • 3042749365 scopus 로고    scopus 로고
    • Eicosapentaenoic acid perturbs signalling via the NFkappaB transcriptional pathway in pancreatic tumour cells
    • Ross, J.A.; Maingay, J.P.; Fearon, J.C.; Sangster, K.; Powell, J.J. Eicosapentaenoic acid perturbs signalling via the NFkappaB transcriptional pathway in pancreatic tumour cells. Int. J. Oncol., 2003, 23(6), 1733-38.
    • (2003) Int. J. Oncol , vol.23 , Issue.6 , pp. 1733-1738
    • Ross, J.A.1    Maingay, J.P.2    Fearon, J.C.3    Sangster, K.4    Powell, J.J.5
  • 154
    • 0032817672 scopus 로고    scopus 로고
    • Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF kappa B activity
    • Lo, C.J.; Chiu, K.C.; Fu, M.; Lo, R.; Helton, S. Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF kappa B activity. J. Surg. Res., 1999, 82(2), 216-222.
    • (1999) J. Surg. Res , vol.82 , Issue.2 , pp. 216-222
    • Lo, C.J.1    Chiu, K.C.2    Fu, M.3    Lo, R.4    Helton, S.5
  • 155
    • 0037214010 scopus 로고    scopus 로고
    • NF-kappa B inhibition by omega -3 fatty acids modulates LPS-stimulated macrophage TNF-alpha transcription
    • Novak, T.E.; Babcock, T.A.; Jho, D.H.; Helton, W.S.; Espat, N.J. NF-kappa B inhibition by omega -3 fatty acids modulates LPS-stimulated macrophage TNF-alpha transcription. Am. J. Physiol. Lung Cell. Mol. Physiol., 2003, 284(1), L84-L89.
    • (2003) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.284 , Issue.1
    • Novak, T.E.1    Babcock, T.A.2    Jho, D.H.3    Helton, W.S.4    Espat, N.J.5
  • 156
    • 1042276587 scopus 로고    scopus 로고
    • Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NF-kappaB activation
    • Zhao, Y.; Joshi-Barve, S.; Barve, S.; Chen, L.H. Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NF-kappaB activation. J. Am. Coll. Nutr., 2004, 23(1), 71-78.
    • (2004) J. Am. Coll. Nutr , vol.23 , Issue.1 , pp. 71-78
    • Zhao, Y.1    Joshi-Barve, S.2    Barve, S.3    Chen, L.H.4
  • 157
    • 33747060171 scopus 로고    scopus 로고
    • Nutritional intervention with omega-3 fatty acids enhances tumor response to anti-neoplastic agents
    • Pardini, R.S. Nutritional intervention with omega-3 fatty acids enhances tumor response to anti-neoplastic agents. Chemicobiol. Interact., 2006, 162(2), 89-105.
    • (2006) Chemicobiol. Interact , vol.162 , Issue.2 , pp. 89-105
    • Pardini, R.S.1
  • 158
    • 6944256628 scopus 로고    scopus 로고
    • Effect of n-3 fatty acids on the antitumour effects of cytotoxic drugs
    • Wynter, M.P.; Russell, S.T.; Tisdale, M.J. Effect of n-3 fatty acids on the antitumour effects of cytotoxic drugs. In vivo, 2004, 18(5), 543-47.
    • (2004) In vivo , vol.18 , Issue.5 , pp. 543-547
    • Wynter, M.P.1    Russell, S.T.2    Tisdale, M.J.3
  • 159
    • 0031000091 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation- induced cell kill
    • Vartak, S.; Robbins, M.E.; Spector, A.A. Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation- induced cell kill. Lipids, 1997, 32(3), 283-92.
    • (1997) Lipids , vol.32 , Issue.3 , pp. 283-292
    • Vartak, S.1    Robbins, M.E.2    Spector, A.A.3
  • 161
    • 33747200855 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and ionizing radiation: Combined cytotoxicity on human colorectal adenocarcinoma cells
    • Benais-Pont, G.; Dupertuis, Y.M.; Kossovsky, M.P.; Nouet, P.; Allal, A.S.; Buchegger, F.; Pichard, C. Omega-3 polyunsaturated fatty acids and ionizing radiation: combined cytotoxicity on human colorectal adenocarcinoma cells. Nutrition, 2006, 22(9), 931-939.
    • (2006) Nutrition , vol.22 , Issue.9 , pp. 931-939
    • Benais-Pont, G.1    Dupertuis, Y.M.2    Kossovsky, M.P.3    Nouet, P.4    Allal, A.S.5    Buchegger, F.6    Pichard, C.7
  • 162
    • 26844490545 scopus 로고    scopus 로고
    • Dietary omega3 fatty acids and ionizing irradiation on human breast cancer xenograft growth and angiogenesis
    • Hardman, W.E.; Sun, L.; Short, N.; Cameron, L.L. Dietary omega3 fatty acids and ionizing irradiation on human breast cancer xenograft growth and angiogenesis. Cancer Cell Int., 2005, 5(1), 12.
    • (2005) Cancer Cell Int , vol.5 , Issue.1 , pp. 12
    • Hardman, W.E.1    Sun, L.2    Short, N.3    Cameron, L.L.4
  • 163
    • 0027416872 scopus 로고
    • Effect of polyunsaturated fatty acids on the drug sensitivity of human tumour cell lines resistant to either cisplatin or doxorubicin
    • Plumb, J.A.; Luo, W.; Kerr, D.J. Effect of polyunsaturated fatty acids on the drug sensitivity of human tumour cell lines resistant to either cisplatin or doxorubicin. Br. J. Cancer, 1993, 67(4), 728-33.
    • (1993) Br. J. Cancer , vol.67 , Issue.4 , pp. 728-733
    • Plumb, J.A.1    Luo, W.2    Kerr, D.J.3
  • 164
    • 7044234956 scopus 로고    scopus 로고
    • Enhancement of arsenic trioxide-mediated apoptosis using docosahexaenoic acid in arsenic trioxide-resistant solid tumor cells
    • Baumgartner, M.; Sturlan, S.; Roth, E.; Wessner, B.; BachleitnerHoffman, T. Enhancement of arsenic trioxide-mediated apoptosis using docosahexaenoic acid in arsenic trioxide-resistant solid tumor cells. Int. J. Cancer, 2004, 112(4), 707-12.
    • (2004) Int. J. Cancer , vol.112 , Issue.4 , pp. 707-712
    • Baumgartner, M.1    Sturlan, S.2    Roth, E.3    Wessner, B.4    BachleitnerHoffman, T.5
  • 166
    • 0038721491 scopus 로고    scopus 로고
    • Docosahexaenoic acid enhances arsenic trioxide-mediated apoptosis in arsenic trioxide-resistant HL-60 cells
    • Sturlan, S.; Baumgartner, M.; Roth, E.; Bachleitner-Hoffman, T. Docosahexaenoic acid enhances arsenic trioxide-mediated apoptosis in arsenic trioxide-resistant HL-60 cells. Blood, 2003, 101(12) 4990-97.
    • (2003) Blood , vol.101 , Issue.12 , pp. 4990-4997
    • Sturlan, S.1    Baumgartner, M.2    Roth, E.3    Bachleitner-Hoffman, T.4
  • 168
    • 33748302272 scopus 로고    scopus 로고
    • Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells
    • Ding, W.Q.; Liu, B.; Vaught, J.L.; Palmiter, R.D.; Lind, S.E. Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Mol. Cancer Ther., 2006, 5(7), 1864-72.
    • (2006) Mol. Cancer Ther , vol.5 , Issue.7 , pp. 1864-1872
    • Ding, W.Q.1    Liu, B.2    Vaught, J.L.3    Palmiter, R.D.4    Lind, S.E.5
  • 169
    • 0030006121 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids increase purine but not pyrimidine transport in L1210 leukaemia cells
    • Martin, D; Meckling-Gill, K.A. Omega-3 polyunsaturated fatty acids increase purine but not pyrimidine transport in L1210 leukaemia cells. Biochem. J., 1996, 315(Pt 1), 329-33.
    • (1996) Biochem. J , vol.315 , Issue.PART 1 , pp. 329-333
    • Martin, D.1    Meckling-Gill, K.A.2
  • 170
    • 9744244362 scopus 로고    scopus 로고
    • Effects of a combination of docosahexaenoic acid and 1,4phenylene bis(methylene) selenocyanate on cyclooxygenase 2, inducible nitric oxide synthase and beta-catenin pathways in colon cancer cells
    • Narayanan, B.; Narayanan, N.; Desai, D.; Pittman, B.; Reddy, B. Effects of a combination of docosahexaenoic acid and 1,4phenylene bis(methylene) selenocyanate on cyclooxygenase 2, inducible nitric oxide synthase and beta-catenin pathways in colon cancer cells. Carcinogenesis, 2004, 25(12), 2443-9.
    • (2004) Carcinogenesis , vol.25 , Issue.12 , pp. 2443-2449
    • Narayanan, B.1    Narayanan, N.2    Desai, D.3    Pittman, B.4    Reddy, B.5
  • 171
    • 4243150252 scopus 로고    scopus 로고
    • Modulation of cyclooxygenase-2 activities by the combined action of celecoxib and decosahexaenoic acid: Novel strategies for colon cancer prevention and treatment
    • Swamy, M.V.; Cooma, I.; Patlolla, J.M.R.; Simi, B.; Reddy, B.S.; Rao C.V. Modulation of cyclooxygenase-2 activities by the combined action of celecoxib and decosahexaenoic acid: novel strategies for colon cancer prevention and treatment. Mol. Cancer Ther., 2004, 3(2), 215-21.
    • (2004) Mol. Cancer Ther , vol.3 , Issue.2 , pp. 215-221
    • Swamy, M.V.1    Cooma, I.2    Patlolla, J.M.R.3    Simi, B.4    Reddy, B.S.5    Rao, C.V.6
  • 172
    • 20344399923 scopus 로고    scopus 로고
    • A combination of docosahexaenoic acid and celecoxib prevents prostate cancer cell growth in vitro and is associated with modulation of nuclear factorkappaB, and steroid hormone receptors
    • Narayanan, N.K.; Narayanan, B.A.; Reddy, B.S. A combination of docosahexaenoic acid and celecoxib prevents prostate cancer cell growth in vitro and is associated with modulation of nuclear factorkappaB, and steroid hormone receptors. Int. J. Oncol., 2005, 26(3), 785-92.
    • (2005) Int. J. Oncol , vol.26 , Issue.3 , pp. 785-792
    • Narayanan, N.K.1    Narayanan, B.A.2    Reddy, B.S.3
  • 173
    • 26844486630 scopus 로고    scopus 로고
    • Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
    • Cha, M.C.; Lin, A.; Meckling, K.A. Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity. BMC Pharmacol., 2005, 5, 7.
    • (2005) BMC Pharmacol , vol.5 , pp. 7
    • Cha, M.C.1    Lin, A.2    Meckling, K.A.3
  • 174
    • 0347595577 scopus 로고    scopus 로고
    • Effect of an omega-3 fatty acid containing lipid emulsion alone and in combination with 5-fluorouracil (5-FU) on growth of the colon cancer cell line Caco-2
    • Jordan, A.; Stein, J. Effect of an omega-3 fatty acid containing lipid emulsion alone and in combination with 5-fluorouracil (5-FU) on growth of the colon cancer cell line Caco-2. Eur. J. Nutr., 2003, 42(6), 324-331.
    • (2003) Eur. J. Nutr , vol.42 , Issue.6 , pp. 324-331
    • Jordan, A.1    Stein, J.2
  • 175
    • 0033928914 scopus 로고    scopus 로고
    • Effects of genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines
    • Nakagawa, H.; Yamamoto, D.; Kiyozuka, Y.; Tsuta, K.; Uemura, Y.; Hioki, K.; Tsutsui, Y.; Tsubura, A. Effects of genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines. J. Cancer Res. Clin. Oncol., 2000, 126(8), 448-54.
    • (2000) J. Cancer Res. Clin. Oncol , vol.126 , Issue.8 , pp. 448-454
    • Nakagawa, H.1    Yamamoto, D.2    Kiyozuka, Y.3    Tsuta, K.4    Uemura, Y.5    Hioki, K.6    Tsutsui, Y.7    Tsubura, A.8
  • 176
    • 0021348672 scopus 로고
    • Effect of cellular fatty acid alteration on adriamycin sensitivity in cultured L1210 murine leukemia cells
    • Guffy, M.M.; North, J.; Burns, C.P. Effect of cellular fatty acid alteration on adriamycin sensitivity in cultured L1210 murine leukemia cells. Cancer Res., 1984, 44(5), 1863-66.
    • (1984) Cancer Res , vol.44 , Issue.5 , pp. 1863-1866
    • Guffy, M.M.1    North, J.2    Burns, C.P.3
  • 177
    • 0022508192 scopus 로고
    • Adriamycin transport and sensitivity in fatty acid-modified leukemia cells
    • Burns, C.P.; North, J.A. Adriamycin transport and sensitivity in fatty acid-modified leukemia cells. Biochim. Biophys. Acta, 1986, 888(1), 10-17.
    • (1986) Biochim. Biophys. Acta , vol.888 , Issue.1 , pp. 10-17
    • Burns, C.P.1    North, J.A.2
  • 178
    • 0035061014 scopus 로고    scopus 로고
    • Cell-specific enhancement of doxorubicin toxicity in human tumour cells by docosahexaenoic acid
    • Rudra, P.K.; Krokan, H.E. Cell-specific enhancement of doxorubicin toxicity in human tumour cells by docosahexaenoic acid. Anticancer Res., 2001, 21(1A), 29-38.
    • (2001) Anticancer Res , vol.21 , Issue.1 A , pp. 29-38
    • Rudra, P.K.1    Krokan, H.E.2
  • 179
    • 0025880615 scopus 로고    scopus 로고
    • Ikushima, S.; Fujiwara, F.; Todo, S.; Imashuku, S. Effects of polyunsaturated fatty acids on vincristine-resistance in human neuroblastoma cells. Ikushima S, Fujiwara F, Todo S, Imashuku S. Anticancer Res., 1991, 11(3), 1215-1220.
    • Ikushima, S.; Fujiwara, F.; Todo, S.; Imashuku, S. Effects of polyunsaturated fatty acids on vincristine-resistance in human neuroblastoma cells. Ikushima S, Fujiwara F, Todo S, Imashuku S. Anticancer Res., 1991, 11(3), 1215-1220.
  • 180
    • 0023512993 scopus 로고
    • Influence of docosahexaenoic acid in vitro on intracellular adriamycin concentration in lymphocytes and human adriamycin-sensitive and -resistant small-cell lung cancer cell lines, and on cytotoxicity in the tumor cell lines
    • Zilstra, J.G.; deVries, E.G.E.; Muskiet, F.A.; Martini, I.A.; Timmer- Bosscha H.; Mulder, N.H. Influence of docosahexaenoic acid in vitro on intracellular adriamycin concentration in lymphocytes and human adriamycin-sensitive and -resistant small-cell lung cancer cell lines, and on cytotoxicity in the tumor cell lines. Int. J. Cancer, 1987, 40(6), 850-56.
    • (1987) Int. J. Cancer , vol.40 , Issue.6 , pp. 850-856
    • Zilstra, J.G.1    deVries, E.G.E.2    Muskiet, F.A.3    Martini, I.A.4    Timmer- Bosscha, H.5    Mulder, N.H.6
  • 181
    • 0025880615 scopus 로고    scopus 로고
    • Effects of polyunsaturated fatty acids on vincristine-resistance in human neuroblastoma cells
    • Ikushima, S.; Fujiwara, F.; Todo, S.; Imashuku, S. Effects of polyunsaturated fatty acids on vincristine-resistance in human neuroblastoma cells. Anticancer Res., 1991, 11(3), 1215-20.
    • (1991) Anticancer Res , vol.11 , Issue.3 , pp. 1215-1220
    • Ikushima, S.1    Fujiwara, F.2    Todo, S.3    Imashuku, S.4
  • 182
    • 0031973280 scopus 로고    scopus 로고
    • Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites? Prostaglandin. Leukotrienes Essen
    • Das, U.N.; Madhavi, N.; Sravan Kumar, G.; Padma, M.; Sangeetha, P. Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites? Prostaglandin. Leukotrienes Essen. Fatty Acids, 1998, 58(1), 39-54.
    • (1998) Fatty Acids , vol.58 , Issue.1 , pp. 39-54
    • Das, U.N.1    Madhavi, N.2    Sravan Kumar, G.3    Padma, M.4    Sangeetha, P.5
  • 183
    • 0034725788 scopus 로고    scopus 로고
    • Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines
    • Lui, Q.Y.; Tan, B.K. Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. Life Sci., 2000, 67(10), 1207-18.
    • (2000) Life Sci , vol.67 , Issue.10 , pp. 1207-1218
    • Lui, Q.Y.1    Tan, B.K.2
  • 184
    • 0027163816 scopus 로고
    • Effects of polyunsaturated fatty acids on the efficacy of antineoplastic agents toward L5178Y lymphoma cells
    • Kinsella, J.E.; Black, J.M. Effects of polyunsaturated fatty acids on the efficacy of antineoplastic agents toward L5178Y lymphoma cells. Biochem. Pharmacol., 1993, 45(9), 1881-87.
    • (1993) Biochem. Pharmacol , vol.45 , Issue.9 , pp. 1881-1887
    • Kinsella, J.E.1    Black, J.M.2
  • 188
    • 85136402355 scopus 로고    scopus 로고
    • Prentice, R.L, Caan, B, Chlebowski, R.T, Patterson, R, Kuller, L.H, Ockene, J.K, Margolis, K.L, Limacher, M.C, Manosn, J.E, Parker, L.M, Paskett, E.P, Phillips, L, Robbinson, J, Rossouw, J.E, Sarto, G.E, Shikany, J.M, Stefanick, M.L, Thomson, C.A, Van Horn, L, Vitolins, M.Z, Wactawski-Wende, J, Wallace, R.B, Wassertheil-Smoller, S, Whitlock, E, Yano, K, AdamsCampbell, L, Anderson, G.L, Asaf, A.R, Beresford, A.A, Black, H.R, Brunner, R.L, Brzyski, R.G, Ford, L, Gass, M, Hays, J, Heber, D, Heiss, G, Hendrix, S.L, Hsia, J, Hubbel, A, Jackson, R.D, Kotchen, J.M, LaCroix, A.Z, Lane, D.S, Langer, R.D, Lasser, N.L, Henderson, M.M. Low-fat dietary pattern and risk of invasive breast cancer: the women's health initiative randomized controlled dietary modification trial. JAMA, 2006, 2956, 629-42
    • Prentice, R.L.; Caan, B.; Chlebowski, R.T.; Patterson, R.; Kuller, L.H.; Ockene, J.K.; Margolis, K.L.; Limacher, M.C.; Manosn, J.E.; Parker, L.M.; Paskett, E.P.; Phillips, L.; Robbinson, J.; Rossouw, J.E.; Sarto, G.E.; Shikany, J.M.; Stefanick, M.L.; Thomson, C.A.; Van Horn, L.; Vitolins, M.Z.; Wactawski-Wende, J.; Wallace, R.B.; Wassertheil-Smoller, S.; Whitlock, E.; Yano, K.; AdamsCampbell, L.; Anderson, G.L.; Asaf, A.R.; Beresford, A.A.; Black, H.R.; Brunner, R.L.; Brzyski, R.G.; Ford, L.; Gass, M.; Hays, J.; Heber, D.; Heiss, G.; Hendrix, S.L.; Hsia, J.; Hubbel, A.; Jackson, R.D.; Kotchen, J.M.; LaCroix, A.Z.; Lane, D.S.; Langer, R.D.; Lasser, N.L.; Henderson, M.M. Low-fat dietary pattern and risk of invasive breast cancer: the women's health initiative randomized controlled dietary modification trial. JAMA, 2006, 295(6), 629-42.
  • 195
    • 40349113534 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Cyclooxygenase/ prostaglandin signaling and breast cancer
    • Howe LR. Inflammation and breast cancer. Cyclooxygenase/ prostaglandin signaling and breast cancer. Breast Cancer Res., 2007, 9(4), 210.
    • (2007) Breast Cancer Res , vol.9 , Issue.4 , pp. 210
    • Howe, L.R.1
  • 196
    • 0032859278 scopus 로고    scopus 로고
    • The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer
    • Barber M.D., Ross J.A., Voss A.C., Tisdale M.J., Fearon K.C. The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer. Br. J. Cancer, 1999, 81(1), 80-86.
    • (1999) Br. J. Cancer , vol.81 , Issue.1 , pp. 80-86
    • Barber, M.D.1    Ross, J.A.2    Voss, A.C.3    Tisdale, M.J.4    Fearon, K.C.5
  • 197
    • 0033041488 scopus 로고    scopus 로고
    • Fish oil-enriched nutritional supplement attenuates progression of the acute-phase response in weight-losing patients with advanced pancreatic cancer
    • Barber M.D., Ross J.A., Preston T., Shenkin A., Fearon K.C. Fish oil-enriched nutritional supplement attenuates progression of the acute-phase response in weight-losing patients with advanced pancreatic cancer. J. Nutr., 1999, 129(6), 1120-25.
    • (1999) J. Nutr , vol.129 , Issue.6 , pp. 1120-1125
    • Barber, M.D.1    Ross, J.A.2    Preston, T.3    Shenkin, A.4    Fearon, K.C.5
  • 198
  • 199
    • 34250641243 scopus 로고    scopus 로고
    • Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia
    • CD004597
    • Dewey A., Baughan C., Dean T., Higgins B., Johnson I. Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia. Cochrane Database Syst. Rev., 2007, 24(1), CD004597.
    • (2007) Cochrane Database Syst. Rev , vol.24 , Issue.1
    • Dewey, A.1    Baughan, C.2    Dean, T.3    Higgins, B.4    Johnson, I.5
  • 200
    • 0031975234 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: A randomized control trial
    • Gogos C.A., Ginopoulos P., Salsa B., Apostolidou E., Zoumbos N.C., Kalfarentzos F. Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial. Cancer, 1998, 82(2), 395-402.
    • (1998) Cancer , vol.82 , Issue.2 , pp. 395-402
    • Gogos, C.A.1    Ginopoulos, P.2    Salsa, B.3    Apostolidou, E.4    Zoumbos, N.C.5    Kalfarentzos, F.6
  • 203
    • 0037208642 scopus 로고    scopus 로고
    • Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: A doubleblind, placebo-controlled study
    • Bruera E., Strasser F., Palmer J.L., Willey J., Calder K., Amyotte G., Baracos V. Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a doubleblind, placebo-controlled study. J. Clin. Oncol., 2003, 21(1), 129-34.
    • (2003) J. Clin. Oncol , vol.21 , Issue.1 , pp. 129-134
    • Bruera, E.1    Strasser, F.2    Palmer, J.L.3    Willey, J.4    Calder, K.5    Amyotte, G.6    Baracos, V.7
  • 204
    • 2942706075 scopus 로고    scopus 로고
    • North Central Cancer Treatement Group. An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: A North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort
    • Jatoi A., Rowland K., Loprinzi C.L., Sloan J.A., Dakhil S.R., MacDonald N., Gagnon B., Novotny P.J., Mailliard J.A., Bushey T.I., Nair S., Christensen B., North Central Cancer Treatement Group. An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort. J. Clin. Oncol., 2004, 22(12), 2469-76.
    • (2004) J. Clin. Oncol , vol.22 , Issue.12 , pp. 2469-2476
    • Jatoi, A.1    Rowland, K.2    Loprinzi, C.L.3    Sloan, J.A.4    Dakhil, S.R.5    MacDonald, N.6    Gagnon, B.7    Novotny, P.J.8    Mailliard, J.A.9    Bushey, T.I.10    Nair, S.11    Christensen, B.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.