Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-δ accelerates intestinal adenoma growth

Nature Medicine

Volumn 10, Issue 3, 2004, Pages 245-247

  Gupta, Rajnish A ^a   Wang, Dingzhi ^a   Katkuri, Sharada ^a   Wang, Haibin ^a   Dey, Sudhansu K ^a   DuBois, Raymond N ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; HORMONE RECEPTOR; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; APC PROTEIN; CELL RECEPTOR; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; DRUG SELECTIVITY; INTESTINE POLYP; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REGULATORY MECHANISM; TUMOR GROWTH; TUMOR VOLUME; ADENOMA; ANIMAL; DOSE RESPONSE; DRUG POTENTIATION; HUMAN; INTESTINE TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ANIMALIA;

ADENOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, APC; HUMANS; INTESTINAL NEOPLASMS; INTESTINAL POLYPS; LIGANDS; MICE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THIAZOLES; TRANSCRIPTION FACTORS;

EID: 1942470331     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm993     Document Type: Article

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