Effects of a combination of docosahexaenoic acid and 1,4-phenylene bis(methylene) selenocyanate on cyclooxygenase 2, inducible nitric oxide synthase and β-catenin pathways in colon cancer cells

Carcinogenesis

Volumn 25, Issue 12, 2004, Pages 2443-2449

  Narayanan, Bhagavathi A ^a   Narayanan, Narayanan K ^a   Desai, Dhimant ^a   Pittman, Brian ^a   Reddy, Bandaru S ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 PHENYLENE DIMETHYLENE SELENOCYANATE; BETA CATENIN; CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; ORGANOSELENIUM DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL LINE; CHEMOPROPHYLAXIS; COLON CANCER; COLON CARCINOGENESIS; CONCENTRATION RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; HUMAN; HUMAN CELL; INCUBATION TIME; LOW DRUG DOSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; CACO-2 CELLS; CELL SURVIVAL; COLONIC NEOPLASMS; CYCLIN D1; CYCLOOXYGENASE 2; CYTOSKELETAL PROTEINS; DOCOSAHEXAENOIC ACIDS; DRUG THERAPY, COMBINATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; ORGANOSELENIUM COMPOUNDS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 9744244362     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh252     Document Type: Article

References (49)

1. Stewart,B.W. and Kleihues,P. (eds) (2003) World Cancer Report. IARC Press, Lyon, France.
2. Jemal,A., Murray,T., Samuels,A., Ghafoor,A., Ward,E. and Thun,M. (2003) Cancer statistics, 2003. CA Cancer J. Clin., 53 5-26.
3. World Cancer Research Fund and American Institute for Cancer Research Panel on Food, Nutrition and the Prevention of Cancer (1997) Food, Nutrition and the Prevention of Cancer: A Global Perspective. American Institute for Cancer Research, Washington, DC, pp. 216-251.
4. Caygill,C.P.J. and Hill,M.J. (1995) Fish, n-3 fatty acids and human colorectal and breast cancer mortality. Eur. J. Cancer Prev., 4, 329-332.
5. Caygill,C.P.J., Charland,S.L. and Lippin,J.A. (1996) Fat, fish, fish oil and cancer. Br. J. Cancer, 74, 159-164,
6. Nigro,N.D., Singh,D.V., Campbell,R.L. and Pak,M.S. (1975) Effect of dietary beef fat on the intestinal tumor formation by azoxymethane in rats. J. Natl Cancer Inst., 54, 439.
7. Reddy,B.S. (1995) Nutritional factors and colon cancer. Crit. Rev. Food Sci. Nutr., 35, 175-190.
8. Chang,W.-C.L., Chapkin,R.S. and Lupton,J.R. (1998) Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation. J. Nutr., 128, 491-497.
9. Reddy,B.S. and Sugie,S. (1988) Effect of different levels of omega-3 and omega-6 fatty acids on azoxymethane-induced colon carcinogenesis in F344 rats. Cancer Res., 48, 6642-6647.
10. Rao,C.V., Hirose,Y., Indranie,C. and Reddy,B.S. (2001) Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids. Cancer Res., 61, 1927-1933.
11. Takahashi,M., Minamoto,T., Yamashita,N., Yawaza,K., Sugimura,T. and Esumi,H. (1993) Reduction in formation and growth of 1,2-dimethylhydrazine-induced aberrant crypt foci in rat colon by docosahexaenoic acid. Cancer Res., 53, 2786-2789.
12. Minoura,T., Takata,T., Sakaguchi,M., Takada,H., Yamamura,M. and Yamamoto,M. (1988) Effect of dietary eicosapentaenoic acid on azoxymethane-induced colon carcinogenesis. Cancer Res., 48, 4790-4794.
13. Hong,M.Y., Chapkin,R.S., Davidson,L.A., Turner,N.D., Morris,J.S., Carroll,R.J. and Lupton,J.R. (2003) Fish oil enhances targeted apoptosis during colon tumor initiation in part by downregulating Bcl-2. Nutr. Cancer, 46, 44-51.
14. Singh,J., Hamid,R. and Reddy,B.S. (1998) Dietary fish oil inhibits the expression of farnesyl protein transferase and colon tumor development in rodents. Carcinogenesis, 18, 985-989.
15. Bancroft,L.K., Lupton,J.R., Davidson,L.A., Taddeo,S.S., Murphy,M.E., Carroll,R.J. and Chapkin,R.S. (2003) Dietary fish oil reduces oxidative DNA damage in rat colonocytes. Free Radic. Biol. Med., 35, 149-159.
16. Fan,Y.Y., Spencer,T.E., Wang,N., Moyer,M.P. and Chapkin,R.S. (2003) Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes. Carcinogenesis, 24, 1541-1548.
17. Davidson,L.A., Lupton,J.R., Miskovsky,E., Fields,A.P. and Chapkin,R.S. (2003) Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study. Biomarkers, 8, 51-61.
18. Narayanan,B.A., Narayanan,N.K. and Reddy,B.S. (2001) Docosahexaenoic acid (DHA) regulated genes and transcription factors inducing apoptosis in human colon cancer cells. Int. J. Oncol., 19, 1255-1262.
19. Narayanan,B.A., Narayanan,N.K., Simi,B. and Reddy,B.S. (2003) Modulation of inducible nitric oxide synthase and related pro-inflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells. Cancer Res., 63, 972-979.
20. Clark,L.C. (1985) The epidemiology of selenium and cancer. Fed. Proc., 44, 2584-2589.
21. Clark,L.C., Combs,G.F.,Jr., Turnbull,B.W. et al. (1996) Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized controlled trial. J. Am. Med. Assoc., 276, 1957-1963.
22. El-Bayoumy,K., Rao,C.V. and Reddy,B.S. (2001) Multiorgan sensitivity to anticarcinogenesis by the organoselenium 1,4-phenylenebis(methylene)-selenocyanate. Nutr. Cancer, 40, 18-27.
23. Ip,C. (1998) Lessons from basic research in selenium and cancer prevention. J. Nutr., 128, 1845-1854.
24. Reddy,B.S., Rivenson,A., Kulkarni,N., Upadhyaya,P. and El-Bayoumy,K. (1992) Chemoprevention of colon carcinogenesis by the synthetic organoselenium compound 1,4-phenylenebis(methylene)selenocyanate. Cancer Res., 52, 5635-5640.
25. Reddy,B.S., Rivenson,A., El-Bayoumy,K. et al. (1997) Chemoprevention of colon cancer by synthetic organoselenoium compounds 1,4-phenylenebis(methylene)selenocyanate and p-methoxy benzyl selenocyanate, in low and/or high fat fed F344 rats. J. Natl Cancer Inst., 89, 506-516.
26. Samaha,H.S., Hamid,R., El-Bayoumy,K., Rao,C.V. and ReddyB.S. (1997) The role of apoptosis in the modulation of colon carcinogenesis by dietary fat and by the organoselenium compound 1,4-phenylenebis(methylene)-selenocyanate. Cancer Epidemiol. Biomarkers Prev., 6, 699-704.
27. Reddy,B.S., Nayini,J., Tokumo,K., Rigotty,J., Zang,E. and Kelloff,G. (1990) Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal antiinflammatory drug with D,L-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet. Cancer Res., 50, 2562-2568.
28. Yamada,Y. and Mori,H. (2003) Pre-cancerous lesions for colorectal cancer in rodents: a new concept. Carcinogenesis, 24 1015-1019.
29. Reddy,B.S., Rivenson,A., Kulkarni,N., Upadhyaya,P. and El-Bayoumy,K. (1992) Chemoprevention of colon carcinogenesis by the synthetic organoselenium compound 1,4-phenylenebis(methylene)selenocyanate. Cancer Res., 52, 5635-5640.
30. El-Bayoumy,K., Das,A., Boyiri,T., Desai,D., Sinha,R., Pittmann,B. and Amin,S. (2003) Comparative action of 1,4-phenylenebis(methylene) selenocyanate and its metabolites against 7,12-dimethylbenz[a] anthracene-DNA adduct formation in the rat and cell proliferation in rat mammary tumor cells. Chem. Biol. Interact., 146, 179-190.
31. Narayanan,B.A., Condon,M.S., Bosland,M.C., Narayanan,N.K. and Reddy,B.S. (2003) Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation and apoptosis mechanism(s). Clin. Cancer Res., 9, 3503-3513.
32. Miller,R.G. (1981) Simultaneous Statistical Inference, 2nd Edn. Springer-Verlag, New York, p. 37.
33. Swamy,M.V., Indranie,C., Patiolla,J.M.R., Simi,B., Reddy,B.S. and Rao,C.V. (2004) Modulation of COX-2 activities by the combined action of colecoxib and docosahexaenoic acid: novel strategies for colon cancer prevention and treatment. Mol. Cancer Ther., 3, 215-221.
34. Miller,J.R. and Moon,R.T. (1996) Signal transduction through β-catenin and specification of cell fate during embryogenesis. Genes Dev., 10, 25-27.
35. Barbletz,T., Jung,A. and Kirchnev,T. (2002) β-catenin and morphogenesis of colorectal cancer. Virchows Arch., 441, 1-11.
36. Yamada,Y., Yoshimi,N., Hirose,Y., Matsunaga,K., Katayama,M., Sakata,K., Shimizu,M., Kuno,T. and Mori,H. (2001) Sequential analysis of morphological and biological properties of β-catenin accumulated crypts provable premalignant lesions independent of aberrant crypt foci in rat colon carcinogenesis. Cancer Res., 61, 1874-1878.
37. Agarwal,B., Rao,C.V., Bhendwal,S., Ramey,W.R., Shirin,H., Reddy,B.S. and Holt,P.R. (1999) Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac. Gastroenterology, 117, 838-8347.
38. Li,H., Pamukcu,R. and Thompson,W.J. (2002) β-Catenin signaling: therapeutic strategies in oncology. Cancer Biol. Ther., 1, 621-625.
39. Yamada,Y., Hamajima,N., Kato,T. et al. (2003) Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer. J. Mol. Med., 81, 126-131.
40. Jen,J., Powell,S.M., Papadopoulos,N., Smith,K.J., Hamilton,S.R., Vogelstein,B. and Kinzler,K.W. (1994) Molecular determinants of dysplasia in colorectal lesions. Cancer Res., 54 5523-5526.
41. Pretlow,T.P., Brasitus,T.A., Fulton,N.C., Cheyer,C. and Kaplan,E.L. (1993) K-ras mutations in putative preneoplastic lesions in human colon. J. Natl Cancer Inst., 85, 2004-2007.
42. Watanabe,K., Kawamori,T., Nakatsugi,S. and Wakabayashi,K. (2000) COX-2 and iNOS, good targets for chemoprevention of colon cancer. Biofactors, 12, 129-133.
43. Hong,M.Y., Lupton,J.R., Morris,J.S., Wang,N., Carroll,R.J., Davidson,L.A., Elder,R.H. and Chapkin,R.S. (2000) Dietary fish oil reduces O6-methylguanine DNA adduct levels in rat colon in part by increasing apoptosis during tumor initiation. Cancer Epidemiol. Biomarkers Prev., 9, 819-826.
44. Chang,W.L., Chapkin,R.S. and Lupton,J.R. (1998) Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation. J. Nutr., 128, 491-497.
45. Ambs,S., Merriam,W.G., Ogunfusika,M.O. et al. (1998) p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells. Nature Med., 4, 1371-1376.
46. Ambs,S., Merrian,W.G., Bennet,W.P. et al. (1998) Frequent nitric oxide synthase-2-expression in human colon adenomas: implication for tumor angiogenesis in colon cancer progression. Cancer Res., 58, 334-341.
47. Rowlands,T.M., Pechenkina,I.V., Hatsell,S.J., Pestell,R.G. and Cowin,P. (2003) Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia. Proc. Natl Acad. Sci. USA 100, 11400-11405.
48. Behrens,J., Mareel,M.M., Van Roy,F.M. and Birchmeier,W. (1989) Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J. Cell Biol., 108, 2435-2447.
49. Vleminckx,K., Vakaet,L.,Jr, Mareel,M., Fiers,W. and van Roy,F. (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell. 66, 107-119.