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Volumn 4, Issue 9, 1998, Pages 1046-1052

Differentiation and reversal of malignant changes in colon cancer through PPARγ

Author keywords

[No Author keywords available]

Indexed keywords

BRL 46593; CARCINOEMBRYONIC ANTIGEN; IBUPROFEN; INDOMETACIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; TROGLITAZONE; UNCLASSIFIED DRUG;

EID: 0031671246     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/2030     Document Type: Article
Times cited : (944)

References (31)
  • 1
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf, D.J. et al. The nuclear receptor superfamily: the second decade. Cell 83, 835-839 (1995).
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1
  • 2
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity: Rounding out the big picture
    • Spiegelman, B.M. & Flier, J.S. Adipogenesis and obesity: rounding out the big picture. Cell 87, 377-389 (1996).
    • (1996) Cell , vol.87 , pp. 377-389
    • Spiegelman, B.M.1    Flier, J.S.2
  • 3
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator- Activated receptor gamma
    • Lehmann, J.M. et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 270, 12953-12956 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1
  • 4
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • Lehmann, J.M., Lenhard, J.M., Oliver, B.B., Ringold, G.M. & Kliewer, S.A. Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 272, 3406-3410 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 5
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
    • Kliewer, S.A. et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83, 813-819 (1995).
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1
  • 6
    • 0028972025 scopus 로고
    • 15-deoxy-Delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman, B.M. et al. 15-deoxy-Delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83, 803-812 (1995).
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1
  • 7
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptor alpha and gamma
    • Kliewer, S.A. et al. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptor alpha and gamma. Proc. Natl. Acad. Sci. USA 94, 4318-4323 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1
  • 8
    • 0030612740 scopus 로고    scopus 로고
    • PPARgamma induces cell cycle withdrawal: Inhibition of E2F/DP DNA binding activity via downregulation of PP2A
    • Altiok, S., Xu, M. & Spiegelman, B.M. PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA binding activity via downregulation of PP2A. Genes Dev. 11, 1987-1998 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 1987-1998
    • Altiok, S.1    Xu, M.2    Spiegelman, B.M.3
  • 9
    • 12644265334 scopus 로고    scopus 로고
    • Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor- Gamma and the retinoid X receptor
    • Tontonoz, P. et al. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor-gamma and the retinoid X receptor. Proc. Natl. Acad. Sci. USA 94, 237-241 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 237-241
    • Tontonoz, P.1
  • 10
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote, M., Li, A.C., Willson, T.M., Kelly, C.J. & Glass, C.K. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391, 79-82 (1998).
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 11
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang, C., Ting, A.T. & Seed, B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391, 82-86 (1998).
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 13
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients
    • Auboeuf, D. et al. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46, 1319-1327 (1997).
    • (1997) Diabetes , vol.46 , pp. 1319-1327
    • Auboeuf, D.1
  • 14
    • 0031844535 scopus 로고    scopus 로고
    • The Nuclear Eicosanoid Receptor, PPARγ, is aberrantly expressed in Colonic Cancers
    • DuBois, R.N. et al. The Nuclear Eicosanoid Receptor, PPARγ, is aberrantly expressed in Colonic Cancers. Carcinogenesis 19, 49-53 (1998).
    • (1998) Carcinogenesis , vol.19 , pp. 49-53
    • Dubois, R.N.1
  • 15
    • 0031009735 scopus 로고    scopus 로고
    • Clinical highlights from the National Cancer Data Base:1997
    • Menck, H.R. et al. Clinical highlights from the National Cancer Data Base:1997. CA Cancer J. Clin. 47, 161-170 (1997).
    • (1997) CA Cancer J. Clin. , vol.47 , pp. 161-170
    • Menck, H.R.1
  • 16
    • 0023925328 scopus 로고
    • Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: A survey of twenty cell lines
    • Chantret, I., Barbat, A., Dussaulx, E., Brattain, M.G. & Zweibaum, A. Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines. Cancer Res 48, 1936-1942 (1988).
    • (1988) Cancer Res , vol.48 , pp. 1936-1942
    • Chantret, I.1    Barbat, A.2    Dussaulx, E.3    Brattain, M.G.4    Zweibaum, A.5
  • 17
    • 0008861608 scopus 로고    scopus 로고
    • Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs
    • Kawai, K. et al. Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs. Arzneimittelforschung 47, 356-368 (1997).
    • (1997) Arzneimittelforschung , vol.47 , pp. 356-368
    • Kawai, K.1
  • 19
    • 0026605203 scopus 로고
    • Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class 1 messenger RNAs associated with colon carcinoma progression and differentiation
    • Kondoh, N., Schweinfest, C.W., Henderson, K.W. & Papas, T.S. Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class 1 messenger RNAs associated with colon carcinoma progression and differentiation. Cancer Res. 52, 791-796 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 791-796
    • Kondoh, N.1    Schweinfest, C.W.2    Henderson, K.W.3    Papas, T.S.4
  • 20
    • 0030962307 scopus 로고    scopus 로고
    • Gene expression profiles in normal and cancer cells
    • Zhang, L. et al. Gene expression profiles in normal and cancer cells. Science 276, 1268-1272 (1997).
    • (1997) Science , vol.276 , pp. 1268-1272
    • Zhang, L.1
  • 21
    • 0025195510 scopus 로고
    • Expression of a Mr 32,000 laminin-binding protein messenger RNa in human colon carcinoma correlates with disease progression
    • Mafune, K. et al. Expression of a Mr 32,000 laminin-binding protein messenger RNA in human colon carcinoma correlates with disease progression. Cancer Res. 50, 3888-3891 (1990).
    • (1990) Cancer Res. , vol.50 , pp. 3888-3891
    • Mafune, K.1
  • 22
    • 0028803770 scopus 로고
    • Failure of programmed cell death and differentiation as causes of tumors: Some simple mathematical models
    • Tomlinson, I.P. & Bodmer, W.F. Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models. Proc. Natl. Acad. Sci. USA 92, 11130-11134 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11130-11134
    • Tomlinson, I.P.1    Bodmer, W.F.2
  • 23
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler, K.W. & Vogelstein, B. Lessons from hereditary colorectal cancer. Cell 87, 159-170 (1996).
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 24
    • 0028603395 scopus 로고
    • Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice
    • Kohl, N.E. et al. Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice. Proc. Natl. Acad. Sci. USA 91, 9141-9145 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9141-9145
    • Kohl, N.E.1
  • 26
    • 0030961889 scopus 로고    scopus 로고
    • Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
    • Selivanova, G. et al. Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain. Nature Med 3, 632-638 (1997).
    • (1997) Nature Med , vol.3 , pp. 632-638
    • Selivanova, G.1
  • 27
    • 0026725932 scopus 로고
    • Studies of intestinal stem cells using normal, chimeric, and transgenic mice
    • Gordon, J.I., Schmidt, G.H. & Roth, K.A. Studies of intestinal stem cells using normal, chimeric, and transgenic mice. FASEB J 6, 3039-3050 (1992).
    • (1992) FASEB J , vol.6 , pp. 3039-3050
    • Gordon, J.I.1    Schmidt, G.H.2    Roth, K.A.3
  • 28
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP Kinase-mediated phosphorylation of PPARgamma
    • Hu, E., Kim, J.B., Sarraf, P. & Spiegelman, B.M. Inhibition of adipogenesis through MAP Kinase-mediated phosphorylation of PPARgamma. Science 274, 2100-2103 (1996).
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 29
    • 0031993322 scopus 로고    scopus 로고
    • Terminal Differentiation of Human Breast Cancer through PPARγ
    • Mueller, E. et al. Terminal Differentiation of Human Breast Cancer through PPARγ. Molecular Cell 1, 465-470 (1998).
    • (1998) Molecular Cell , vol.1 , pp. 465-470
    • Mueller, E.1
  • 30
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nolan, J.J., Ludvik, B., Beerdsen, P., Joyce, M. & Olefsky, J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N. Engl. J. Med. 331, 1188-1193 (1994).
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3    Joyce, M.4    Olefsky, J.5
  • 31
    • 0030894288 scopus 로고    scopus 로고
    • Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer
    • Levy, G.N. Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer. FASEB J 11, 234-247 (1997).
    • (1997) FASEB J , vol.11 , pp. 234-247
    • Levy, G.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.