Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

Journal of Experimental Medicine

Volumn 201, Issue 5, 2005, Pages 713-722

  Arita, Makoto ^a   Bianchini, Francesca ^a   Aliberti, Julio ^b   Sher, Alan ^b   Chiang, Nan ^a   Hong, Song ^a   Yang, Rong ^c   Petasis, Nicos A ^c   Serhan, Charles N ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESSENTIAL FATTY ACID; FISH OIL; G PROTEIN COUPLED RECEPTOR; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; LIPID; OMEGA 3 FATTY ACID; RESOLVIN E1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARDIOVASCULAR DISEASE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG ACTIVITY; HUMAN; HUMAN TISSUE; INFLAMMATION; NONHUMAN; PERITONITIS; PHYSICAL CAPACITY; PLASMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; REGULATORY MECHANISM; SKIN INFLAMMATION; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; ANIMALS; DENDRITIC CELLS; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; LIGANDS; MALE; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PHYLOGENY; RADIOLIGAND ASSAY; RECEPTORS, CHEMOKINE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SPLEEN;

EID: 12344321136     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20042031     Document Type: Article

References (28)

1. De Caterina, R., S. Endres, S.D. Kristensen, and E.B. Schmidt. 1993. N-3 Fatty Acids and Vascular Disease. Bi & Gi Publishers, Verona. 166 pp.
2. GISSI-Prevenzione Investigators. 1999. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet. 354:447-455.
3. Albert, C.M., H. Campos, M.J. Stampfer, P.M. Ridker, J. Manson, W.C. Willett, and J. Ma. 2002. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N. Engl. J. Med. 346:1113-1118.
4. Weiss, U. 2002. Insight: inflammation. Nature. 420:845-891.
5. Funk, C.D. 2001. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 294:1871-1875.
6. Rowley, A.F., D.J. Hill, C.E. Ray, and R. Munro. 1997. Haemostasis in fish, an evolutionary perspective. Thromb. Haemost. 77:227-233.
7. Serhan, C.N., C.B. Clish, J. Brannon, S.P. Colgan, N. Chiang, and K. Gronert. 2000. Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J. Exp. Med. 192:1197-1204.
8. Serhan, C.N., S. Hong, K. Gronert, C.P. Colgan, P.R. Devchand, G. Mirick, and R. Moussignac. 2002. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196: 1025-1037.
9. Clish, C.B., J.A. O'Brien, K. Gronert, G.L. Stahl, N.A. Petasis, and C.N. Serhan. 1999. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc. Natl. Acad. Sci. USA. 96:8247-8252.
10. Lawrence, T., D.A. Willoughby, and D.W. Gilroy. 2002. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat. Rev. Immunol. 2:787-795.
11. Tessier, P.A., P.H. Naccache, I. Clark-Lewis, R.P. Gladue, K.S. Neote, and S.R. McColl. 1997. Chemokine networks in vivo. Involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-α. J. Immunol. 159:3595-3602.
12. McMahon, B., S. Mitchell, H.R. Brady, and C. Godson. 2001. Lipoxins: revelations on resolution. Trends Phamacol. Sci. 22:391-395.
13. Yokomizo, T., T. Izumi, K. Chang, Y. Takuwa, and T. Shimizu. 1997. A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature. 387:620-624.
14. Gewirtz, A.T., L.S. Collier-Hyams, A.N. Young, T. Kucharzik, W.J. Guilford, J.F. Parkinson, I.R. Williams, A.S. Neish, and J.L. Madara. 2002. Lipoxin A4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. J. Immunol. 168:5260-5267.
15. Samson, M., A.L. Edinger, P. Stordeur, J. Rucker, V. Verhasselt, M. Sharron, C. Govaerts, C. Mollereau, G. Vassart, R.W. Doms, and M. Parmentier. 1998. ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains. Eur. J. Immunol. 28:1689-1700.
16. Kopp, E., and S. Ghosh. 1994. Inhibition of NF-κB by sodium salicylate and aspirin. Science. 265:956-959.
17. Wittamer, V., J. Franssen, M. Vulcano, J. Mirjolet, E. Le Poul, I. Migeotte, S. Brezillon, R. Tyldesley, C. Blanpain, M. Detheux, et al. 2003. Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. J. Exp. Med. 198:977-985.
18. Methner, A., G. Hermey, B. Schinke, and I. Hermans-Borgmeyer. 1997. A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development. Biochem. Biophys. Res. Commun. 233:336-342.
19. Endres, S., R. Ghorbani, V.E. Kelley, K. Georgilis, G. Lonnemann, J.W. van der Meer, J.G. Cannon, T.S. Rogers, M.S. Klempner, and P.C. Weber. 1989. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N. Engl. J. Med. 320:265-271.
20. Aliberti, J., S. Hieny, C. Reis e Sousa, C.N. Serhan, and A. Sher. 2002. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nat. Immunol. 3:76-82.
21. Nathan, C. 2002. Points of control in inflammation. Nature. 420:846-852.
22. Topper, J.N., J. Cai, D. Falb, and M.A. Gimbrone Jr. 1996. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganase superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc. Natl. Acad. Sci. USA. 93:10417-10422.
23. Cheng, Y., S.C. Austin, B. Rocca, B.H. Koller, T.M. Coffman, T. Grosser, J.A. Lawson, and G.A. FitzGerald. 2002. Role of prostacyclin in the cardiovascular response to thromboxane A2. Science. 296:539-541.
24. Serhan, C.N. 2002. Endogenous chemical mediators in anti-inflammation and pro-resolution. Curr. Med. Chem. 1:177-192.
25. Chiang, N., I.M. Fierro, K. Gronert, and C.N. Serhan. 2000. Activation of lipoxin A4 receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation. J. Exp. Med. 191:1197-1207.
26. Perretti, M. 2003. The annexin 1 receptor(s): is the plot unravelling? Trends Pharmacol. Sci. 24:574-579.
27. Gronert, K., S.P. Colgan, and C.N. Serhan. 1998. Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation. J. Pharmacol Exp. Ther. 285:252-261.
28. Capdevila, J.H., S. Wei, C. Helvig, J.R. Falck, Y. Belosludtsev, G. Truan, S.E. Graham-Lorence, and J.A. Peterson. 1996. The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. J. Biol. Chem. 271:22663-22671.