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Volumn 3, Issue 3, 2004, Pages 201-215

Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy

Author keywords

Cancer; Immediate early genes; Ionizing radiation; P53; Promoter; Radiotherapy; X rays

Indexed keywords

ANTINEOPLASTIC AGENT; EARLY GROWTH RESPONSE FACTOR 1; GANCICLOVIR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE RECEPTOR; PROTEIN C JUN; PROTEIN FOS; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR SUPPRESSOR PROTEIN;

EID: 0842346433     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2003.12.002     Document Type: Review
Times cited : (33)

References (109)
  • 3
    • 0141645610 scopus 로고    scopus 로고
    • Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation
    • Criswell T., Leskov K., Miyamoto S., Luo G., Boothmanl D.A. Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation. Oncogene. 22:2003;5813-5827.
    • (2003) Oncogene , vol.22 , pp. 5813-5827
    • Criswell, T.1    Leskov, K.2    Miyamoto, S.3    Luo, G.4    Boothmanl, D.A.5
  • 4
    • 0014800128 scopus 로고
    • Effects of X-irradiation on RNA and protein synthesis in HeLa cells
    • Kim S.H., Kim J.H., Djordjevic B. Effects of X-irradiation on RNA and protein synthesis in HeLa cells. Radiat. Res. 42:1970;577-589.
    • (1970) Radiat. Res. , vol.42 , pp. 577-589
    • Kim, S.H.1    Kim, J.H.2    Djordjevic, B.3
  • 5
    • 0028141973 scopus 로고
    • Radiation induction of immediate early genes: Effectors of the radiation-stress response
    • Weichselbaum R.R., Hallahan D., Fuks Z., Kufe D. Radiation induction of immediate early genes: effectors of the radiation-stress response. Int. J. Radiat. Oncol. Biol. Phys. 30:1994;229-234.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.30 , pp. 229-234
    • Weichselbaum, R.R.1    Hallahan, D.2    Fuks, Z.3    Kufe, D.4
  • 6
    • 0021213870 scopus 로고
    • Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
    • Greenberg M.E., Ziff E.B. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature. 311:1984;433-438.
    • (1984) Nature , vol.311 , pp. 433-438
    • Greenberg, M.E.1    Ziff, E.B.2
  • 7
    • 0035188856 scopus 로고    scopus 로고
    • Gene expression profiles for monitoring radiation exposure
    • Amundson S.A., Fornace A.J. Gene expression profiles for monitoring radiation exposure. Radiat. Prot. Dosim. 97:2001;11-16.
    • (2001) Radiat. Prot. Dosim. , vol.97 , pp. 11-16
    • Amundson, S.A.1    Fornace, A.J.2
  • 8
    • 0029129311 scopus 로고
    • Induction of transcription of "immediate early genes" by low-dose ionizing radiation
    • Prasad A.V., Mohan N., Chandrasekar B., Meltz M.L. Induction of transcription of "immediate early genes" by low-dose ionizing radiation. Radiat. Res. 143:1995;263-272.
    • (1995) Radiat. Res. , vol.143 , pp. 263-272
    • Prasad, A.V.1    Mohan, N.2    Chandrasekar, B.3    Meltz, M.L.4
  • 10
    • 0029132287 scopus 로고
    • Regulation of the c-fos promoter
    • Janknecht R. Regulation of the c-fos promoter. Immunobiology. 193:1995;137-142.
    • (1995) Immunobiology , vol.193 , pp. 137-142
    • Janknecht, R.1
  • 11
    • 0022137059 scopus 로고
    • Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences
    • Treisman R. Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences. Cell. 42:1985;889-902.
    • (1985) Cell , vol.42 , pp. 889-902
    • Treisman, R.1
  • 13
    • 0036295848 scopus 로고    scopus 로고
    • Serum response factor: Discovery, biochemistry, biological roles and implications for tissue injury healing
    • Chai J., Tarnawski A.S. Serum response factor: discovery, biochemistry, biological roles and implications for tissue injury healing. J. Physiol. Pharmacol. 53:2002;147-157.
    • (2002) J. Physiol. Pharmacol. , vol.53 , pp. 147-157
    • Chai, J.1    Tarnawski, A.S.2
  • 14
    • 0036358038 scopus 로고    scopus 로고
    • MAPK-regulated transcription: A continuously variable gene switch?
    • Hazzalin C., Mahadevan L.C. MAPK-regulated transcription: a continuously variable gene switch? Nat. Rev. Mol. Cell Biol. 3:2002;30-40.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 30-40
    • Hazzalin, C.1    Mahadevan, L.C.2
  • 15
    • 0036549937 scopus 로고    scopus 로고
    • Complexities in ETS-domain transcription factor function and regulation: Lessons from the TCF (ternary complex factor) subfamily. the Colworth Medal Lecture
    • Sharrocks A.D. Complexities in ETS-domain transcription factor function and regulation: lessons from the TCF (ternary complex factor) subfamily. The Colworth Medal Lecture. Biochem. Soc. Trans. 30:2002;1-9.
    • (2002) Biochem. Soc. Trans. , vol.30 , pp. 1-9
    • Sharrocks, A.D.1
  • 21
    • 0038037235 scopus 로고    scopus 로고
    • Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2
    • Kool J., Hamdi M., Cornelissen-Steijger P., van der Eb A.J., Terleth C., van Dam H. Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2. Oncogene. 22:2003;4235-4242.
    • (2003) Oncogene , vol.22 , pp. 4235-4242
    • Kool, J.1    Hamdi, M.2    Cornelissen-Steijger, P.3    Van Der Eb, A.J.4    Terleth, C.5    Van Dam, H.6
  • 22
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J., Whitmarsh A.J., Barrett T., Derijard B., Davis R.J. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell Biol. 16:1996;1247-1255.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 24
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel P., Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta. 1072:1991;129-157.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 25
    • 0036511547 scopus 로고    scopus 로고
    • Reactive oxygen species and regulation of gene expression
    • Turpaev K.T. Reactive oxygen species and regulation of gene expression. Biochem. (Mosc.). 67:2002;281-292.
    • (2002) Biochem. (Mosc.) , vol.67 , pp. 281-292
    • Turpaev, K.T.1
  • 26
    • 0025879694 scopus 로고
    • Ionizing radiation induces expression and binding activity of the nuclear factor kappa B
    • Brach M.A., Hass R., Sherman M.L., Gunji H., Weichselbaum R., Kufe D. Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. J. Clin. Invest. 88:1991;691-695.
    • (1991) J. Clin. Invest. , vol.88 , pp. 691-695
    • Brach, M.A.1    Hass, R.2    Sherman, M.L.3    Gunji, H.4    Weichselbaum, R.5    Kufe, D.6
  • 27
    • 0028271882 scopus 로고
    • Activation of nuclear factor kappa B in human lymphoblastoid cells by low-dose ionizing radiation
    • Prasad A.V., Mohan N., Chandrasekar B., Meltz M.L. Activation of nuclear factor kappa B in human lymphoblastoid cells by low-dose ionizing radiation. Radiat. Res. 138:1994;367-372.
    • (1994) Radiat. Res. , vol.138 , pp. 367-372
    • Prasad, A.V.1    Mohan, N.2    Chandrasekar, B.3    Meltz, M.L.4
  • 28
    • 0036798751 scopus 로고    scopus 로고
    • Radiation-induced activation of nuclear factor-kappaB involves selective degradation of plasma membrane-associated I(kappa) B(alpha)
    • Russell J.S., Tofilon P.J. Radiation-induced activation of nuclear factor-kappaB involves selective degradation of plasma membrane-associated I(kappa) B(alpha). Mol. Biol. Cell. 13:2002;3431-3440.
    • (2002) Mol. Biol. Cell. , vol.13 , pp. 3431-3440
    • Russell, J.S.1    Tofilon, P.J.2
  • 29
    • 0027999283 scopus 로고
    • Induction of nuclear factor kappa B after low-dose ionizing radiation involves a reactive oxygen intermediate signaling pathway
    • Mohan N., Meltz M.L. Induction of nuclear factor kappa B after low-dose ionizing radiation involves a reactive oxygen intermediate signaling pathway. Radiat. Res. 140:1994;97-104.
    • (1994) Radiat. Res. , vol.140 , pp. 97-104
    • Mohan, N.1    Meltz, M.L.2
  • 30
    • 0032497587 scopus 로고    scopus 로고
    • A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB
    • Lee S.J., Dimtchev A., Lavin M.F., Dritschilo A., Jung M. A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB. Oncogene. 17:1998;1821-1826.
    • (1998) Oncogene , vol.17 , pp. 1821-1826
    • Lee, S.J.1    Dimtchev, A.2    Lavin, M.F.3    Dritschilo, A.4    Jung, M.5
  • 31
    • 0032573165 scopus 로고    scopus 로고
    • Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms
    • Li N., Karin M. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc. Natl. Acad. Sci. U.S.A. 95:1998;13012-13017.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 13012-13017
    • Li, N.1    Karin, M.2
  • 32
    • 0036802356 scopus 로고    scopus 로고
    • The role of NF-kappaB in the regulation of cell stress responses
    • Wang T., Zhang X., Li J.J. The role of NF-kappaB in the regulation of cell stress responses. Int. Immunopharmacol. 2:2002;1509-1520.
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 1509-1520
    • Wang, T.1    Zhang, X.2    Li, J.J.3
  • 33
    • 0036770176 scopus 로고    scopus 로고
    • Radiosensitization by overexpression of the nonphosphorylation form of IkappaB-alpha in human glioma cells
    • Honda N., Yagi K., Ding G.R., Miyakoshi J. Radiosensitization by overexpression of the nonphosphorylation form of IkappaB-alpha in human glioma cells. J. Radiat. Res. (Tokyo). 43:2002;283-292.
    • (2002) J. Radiat. Res. (Tokyo) , vol.43 , pp. 283-292
    • Honda, N.1    Yagi, K.2    Ding, G.R.3    Miyakoshi, J.4
  • 35
    • 0037089516 scopus 로고    scopus 로고
    • Inhibition of radiation-induced nuclear factor-kappaB activation by an anti-Ras single-chain antibody fragment: Lack of involvement in radiosensitization
    • Russell J.S., Raju U., Gumin G.J., Lang F.F., Wilson D.R., Huet T., Tofilon P.J. Inhibition of radiation-induced nuclear factor-kappaB activation by an anti-Ras single-chain antibody fragment: lack of involvement in radiosensitization. Cancer Res. 62:2002;2318-2326.
    • (2002) Cancer Res. , vol.62 , pp. 2318-2326
    • Russell, J.S.1    Raju, U.2    Gumin, G.J.3    Lang, F.F.4    Wilson, D.R.5    Huet, T.6    Tofilon, P.J.7
  • 36
    • 0034103697 scopus 로고    scopus 로고
    • Full promoter sequence of human early growth response factor-1 (EGR-1): Demonstration of a fifth functional serum response element
    • Schwachtgen J.L., Campbell C.J., Braddock M. Full promoter sequence of human early growth response factor-1 (EGR-1): demonstration of a fifth functional serum response element. DNA Seq. 10:2000;429-432.
    • (2000) DNA Seq. , vol.10 , pp. 429-432
    • Schwachtgen, J.L.1    Campbell, C.J.2    Braddock, M.3
  • 37
    • 0027512020 scopus 로고
    • Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation
    • Datta R., Taneja N., Sukhatme V.P., Qureshi S.A., Weichselbaum R., Kufe D.W. Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation. Proc. Natl. Acad. Sci. U.S.A. 90:1993;2419-2422.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 2419-2422
    • Datta, R.1    Taneja, N.2    Sukhatme, V.P.3    Qureshi, S.A.4    Weichselbaum, R.5    Kufe, D.W.6
  • 38
    • 0032482367 scopus 로고    scopus 로고
    • Stress-induced immediated-early gene, egr-1, involves activation of p38/JNK1
    • Lim C.P., Jain N., Cao X. Stress-induced immediated-early gene, egr-1, involves activation of p38/JNK1. Oncogene. 16:1998;2915-2926.
    • (1998) Oncogene , vol.16 , pp. 2915-2926
    • Lim, C.P.1    Jain, N.2    Cao, X.3
  • 39
    • 0035879004 scopus 로고    scopus 로고
    • Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells
    • Suzuki K., Kodama S., Watanabe M. Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells. Cancer Res. 61:2001;5396-5401.
    • (2001) Cancer Res. , vol.61 , pp. 5396-5401
    • Suzuki, K.1    Kodama, S.2    Watanabe, M.3
  • 40
    • 0036151103 scopus 로고    scopus 로고
    • Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro
    • Meyer R.G., Kupper J.H., Kandolf R., Rodemann H.P. Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro. Eur. J. Biochem. 269:2002;337-346.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 337-346
    • Meyer, R.G.1    Kupper, J.H.2    Kandolf, R.3    Rodemann, H.P.4
  • 42
    • 0030793887 scopus 로고    scopus 로고
    • Coactivation of AP-1 activity and TGF-β1 gene expression in the stress response of normal skin cells to ionizing radiation
    • Martin M., Vozenin M.-C., Gault N., Crechet F., Pfarr C.M., Lefaix J.-L. Coactivation of AP-1 activity and TGF-β1 gene expression in the stress response of normal skin cells to ionizing radiation. Oncogene. 15:1997;981-989.
    • (1997) Oncogene , vol.15 , pp. 981-989
    • Martin, M.1    Vozenin, M.-C.2    Gault, N.3    Crechet, F.4    Pfarr, C.M.5    Lefaix, J.-L.6
  • 43
    • 0032532206 scopus 로고    scopus 로고
    • Suppression of TGF-β-induced apoptosis through a PI3/Akt-dependent pathway
    • Chen R.H., Su Y.H., Chuang R.L., Chang T.Y. Suppression of TGF-β-induced apoptosis through a PI3/Akt-dependent pathway. Oncogene. 17:1998;1959-1968.
    • (1998) Oncogene , vol.17 , pp. 1959-1968
    • Chen, R.H.1    Su, Y.H.2    Chuang, R.L.3    Chang, T.Y.4
  • 44
    • 0024420683 scopus 로고
    • Effects of irradiation on the release of growth factors from cultured bovine, porcine, and human endothelial cells
    • Witte L., Fuks Z., Haimovitz-Friedman A., Vlodavsky I., Goodman D.S., Eldor A. Effects of irradiation on the release of growth factors from cultured bovine, porcine, and human endothelial cells. Cancer Res. 49:1989;5066-5072.
    • (1989) Cancer Res. , vol.49 , pp. 5066-5072
    • Witte, L.1    Fuks, Z.2    Haimovitz-Friedman, A.3    Vlodavsky, I.4    Goodman, D.S.5    Eldor, A.6
  • 45
    • 0028793693 scopus 로고
    • Effect of ionizing radiation on AP-1 binding activity and basic fibroblast growth factor gene expression in drug-sensitive human breast carcinoma MCF-7 and multidrug-resistant MCF-7/ADR cells
    • Lee J.Y., Galoforo S.S., Berns C., Erdos G., Gupta A.K., Ways D.K., Corry P.M. Effect of ionizing radiation on AP-1 binding activity and basic fibroblast growth factor gene expression in drug-sensitive human breast carcinoma MCF-7 and multidrug-resistant MCF-7/ADR cells. J. Biol. Chem. 270:1995;28790-28796.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28790-28796
    • Lee, J.Y.1    Galoforo, S.S.2    Berns, C.3    Erdos, G.4    Gupta, A.K.5    Ways, D.K.6    Corry, P.M.7
  • 46
    • 0037136673 scopus 로고    scopus 로고
    • The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit
    • Ader I., Muller C., Bonnet J., Favre G., Cohen-Jonathan E., Salles B., Toulas C. The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit. Oncogene. 21:2002;6471-6479.
    • (2002) Oncogene , vol.21 , pp. 6471-6479
    • Ader, I.1    Muller, C.2    Bonnet, J.3    Favre, G.4    Cohen-Jonathan, E.5    Salles, B.6    Toulas, C.7
  • 47
    • 0037026602 scopus 로고    scopus 로고
    • RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death
    • Ader I., Toulas C., Dalenc F., Delmas C., Bonnet J., Cohen-Jonathan E., Favre G. RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death. Oncogene. 21:2002;5998-6006.
    • (2002) Oncogene , vol.21 , pp. 5998-6006
    • Ader, I.1    Toulas, C.2    Dalenc, F.3    Delmas, C.4    Bonnet, J.5    Cohen-Jonathan, E.6    Favre, G.7
  • 48
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell. 100:2000;57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 52
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 53
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist C.J., Kastan M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 421:2003;499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 55
    • 0025024469 scopus 로고
    • Presence of a potent transcription activating sequence in the p53 protein
    • Fields S., Jang S.K. Presence of a potent transcription activating sequence in the p53 protein. Science. 249:1990;1046-1049.
    • (1990) Science , vol.249 , pp. 1046-1049
    • Fields, S.1    Jang, S.K.2
  • 56
  • 57
    • 0027749169 scopus 로고
    • A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein
    • Bargonetti J., Manfredi J.J., Chen X., Marshak D.R., Prives C. A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev. 7:1993;2565-2574.
    • (1993) Genes Dev. , vol.7 , pp. 2565-2574
    • Bargonetti, J.1    Manfredi, J.J.2    Chen, X.3    Marshak, D.R.4    Prives, C.5
  • 59
    • 0038491354 scopus 로고    scopus 로고
    • Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305
    • Wang Y.H., Tsay Y.G., Tan B.C., Lo W.Y., Lee S.C. Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305. J. Biol. Chem. 278:2003;25568-25576.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25568-25576
    • Wang, Y.H.1    Tsay, Y.G.2    Tan, B.C.3    Lo, W.Y.4    Lee, S.C.5
  • 63
    • 0141757504 scopus 로고    scopus 로고
    • P53 and radiation responses
    • Fei P., El-Deiry W.S. P53 and radiation responses. Oncogene. 22:2003;5774-5783.
    • (2003) Oncogene , vol.22 , pp. 5774-5783
    • Fei, P.1    El-Deiry, W.S.2
  • 64
    • 0842278332 scopus 로고    scopus 로고
    • Microarray analysis of p53-mediated transcription: Multi-thousand piece puzzle or invitation to collective thinking
    • Gudkov A. Microarray analysis of p53-mediated transcription: multi-thousand piece puzzle or invitation to collective thinking. Cancer Biol. Ther. 2:2003;444-445.
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 444-445
    • Gudkov, A.1
  • 65
    • 0842300074 scopus 로고    scopus 로고
    • Microarray analysis of p53 target gene expression patterns in the spleen and thymus in response to ionizing radiation
    • Burns T.F., El-Deiry W.S. Microarray analysis of p53 target gene expression patterns in the spleen and thymus in response to ionizing radiation. Cancer Biol. Ther. 2:2003;431-443.
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 431-443
    • Burns, T.F.1    El-Deiry, W.S.2
  • 67
    • 0006470452 scopus 로고    scopus 로고
    • Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses
    • Amundson S.A., Bittner M., Chen Y., Trent J., Meltzer P., Fornace A.J. Jr. Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses. Oncogene. 18:1999;3666-3672.
    • (1999) Oncogene , vol.18 , pp. 3666-3672
    • Amundson, S.A.1    Bittner, M.2    Chen, Y.3    Trent, J.4    Meltzer, P.5    Fornace Jr., A.J.6
  • 68
    • 0035800746 scopus 로고    scopus 로고
    • Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein
    • Koutsodontis G., Tentes I., Papakosta P., Moustakas A., Kardassis D. Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein. J. Biol. Chem. 276:2001;29116-29125.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29116-29125
    • Koutsodontis, G.1    Tentes, I.2    Papakosta, P.3    Moustakas, A.4    Kardassis, D.5
  • 70
    • 0029074748 scopus 로고
    • Irradiation induces WAF1 expression through a p53-independent pathway in KG-1 cells
    • Akashi M., Hachiya M., Osawa Y., Spirin K., Suzuki G., Koeffler H.P. Irradiation induces WAF1 expression through a p53-independent pathway in KG-1 cells. J. Biol. Chem. 270:1995;19181-19187.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19181-19187
    • Akashi, M.1    Hachiya, M.2    Osawa, Y.3    Spirin, K.4    Suzuki, G.5    Koeffler, H.P.6
  • 73
    • 0033529121 scopus 로고    scopus 로고
    • Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45
    • Zhan Q., Antinore M.J., Wang X.W., Carrier F., Smith M.L., Harris C.C., Fornace A.J. Jr. Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45. Oncogene. 18:1999;2892-2900.
    • (1999) Oncogene , vol.18 , pp. 2892-2900
    • Zhan, Q.1    Antinore, M.J.2    Wang, X.W.3    Carrier, F.4    Smith, M.L.5    Harris, C.C.6    Fornace Jr., A.J.7
  • 74
    • 0032878399 scopus 로고    scopus 로고
    • Induction of stress genes by low doses of gamma rays
    • Amundson S.A., Do K.T., Fornace A.J. Jr. Induction of stress genes by low doses of gamma rays. Radiat. Res. 152:1999;225-231.
    • (1999) Radiat. Res. , vol.152 , pp. 225-231
    • Amundson, S.A.1    Do, K.T.2    Fornace Jr., A.J.3
  • 76
    • 0037126303 scopus 로고    scopus 로고
    • Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • Seoane J., Le H.V., Massague J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature. 419:2002;729-734.
    • (2002) Nature , vol.419 , pp. 729-734
    • Seoane, J.1    Le H., V.2    Massague, J.3
  • 77
    • 0030871457 scopus 로고    scopus 로고
    • P53-dependent DNA damage-induced apoptosis requires Fas/ APO-1-independent activation of CPP32beta
    • Fuchs E.J., McKenna K.A., Bedi A. p53-dependent DNA damage-induced apoptosis requires Fas/APO-1-independent activation of CPP32beta. Cancer Res. 57:1997;2550-2554.
    • (1997) Cancer Res. , vol.57 , pp. 2550-2554
    • Fuchs, E.J.1    McKenna, K.A.2    Bedi, A.3
  • 79
    • 0034732258 scopus 로고    scopus 로고
    • Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
    • Takimoto R., El-Deiry W.S. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene. 19:2000;1735-1743.
    • (2000) Oncogene , vol.19 , pp. 1735-1743
    • Takimoto, R.1    El-Deiry, W.S.2
  • 82
    • 0027944228 scopus 로고
    • Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
    • Zhan Q., Fan S., Bae I., Guillouf C., Liebermann D.A., O'Connor P.M., Fornace A.J. Jr. Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene. 9:1994;3743-3751.
    • (1994) Oncogene , vol.9 , pp. 3743-3751
    • Zhan, Q.1    Fan, S.2    Bae, I.3    Guillouf, C.4    Liebermann, D.A.5    O'Connor, P.M.6    Fornace Jr., A.J.7
  • 83
    • 0029669929 scopus 로고    scopus 로고
    • T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53 gene product in
    • Brady H.J., Salomons G.S., Bobeldijk R.C., Berns A.J. T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53 gene product in. EMBO J. 15:1996;1221-1230.
    • (1996) EMBO J. , vol.15 , pp. 1221-1230
    • Brady, H.J.1    Salomons, G.S.2    Bobeldijk, R.C.3    Berns, A.J.4
  • 84
    • 0030938089 scopus 로고    scopus 로고
    • Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
    • McCurrach M.E., Connor T.M., Knudson C.M., Korsmeyer S.J., Lowe S.W. Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc. Natl. Acad. Sci. U.S.A. 94:1997;2345-2349.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 2345-2349
    • McCurrach, M.E.1    Connor, T.M.2    Knudson, C.M.3    Korsmeyer, S.J.4    Lowe, S.W.5
  • 88
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell. 7:2001;683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 91
    • 0025359095 scopus 로고
    • The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines
    • Hallahan D.E., Beckett M.A., Kufe D., Weichselbaum R.R. The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines. Int. J. Radiat. Oncol. Biol. Phys. 19:1990;69-74.
    • (1990) Int. J. Radiat. Oncol. Biol. Phys. , vol.19 , pp. 69-74
    • Hallahan, D.E.1    Beckett, M.A.2    Kufe, D.3    Weichselbaum, R.R.4
  • 95
    • 0029559345 scopus 로고
    • Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir
    • Joki T., Nakamura M., Ohno T. Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir. Hum. Gene Ther. 6:1995;1507-1513.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 1507-1513
    • Joki, T.1    Nakamura, M.2    Ohno, T.3
  • 96
    • 0009416244 scopus 로고
    • A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences
    • Christy B.A., Lau L.F., Nathans D. A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences. Proc. Natl. Acad. Sci. U.S.A. 85:1988;7857-7861.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 7857-7861
    • Christy, B.A.1    Lau, L.F.2    Nathans, D.3
  • 98
    • 0036773207 scopus 로고    scopus 로고
    • Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy
    • Scott S.D., Joiner M.C., Marples B. Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Ther. 9:2002;1396-1402.
    • (2002) Gene Ther. , vol.9 , pp. 1396-1402
    • Scott, S.D.1    Joiner, M.C.2    Marples, B.3
  • 101
    • 0037270366 scopus 로고    scopus 로고
    • Dual induction of the Epo-Egr-TNF-alpha-plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay
    • Salloum R.M., Mauceri H.J., Hanna N.N., Gorski D.H., Posner M.C., Weichselbaum R.R. Dual induction of the Epo-Egr-TNF-alpha-plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay. Am. Surg. 69:2003;24-27.
    • (2003) Am. Surg. , vol.69 , pp. 24-27
    • Salloum, R.M.1    Mauceri, H.J.2    Hanna, N.N.3    Gorski, D.H.4    Posner, M.C.5    Weichselbaum, R.R.6
  • 102
    • 0033911027 scopus 로고    scopus 로고
    • Modification of vascular tone using iNOS under the control of a radiation-inducible promoter
    • Worthington J., Robson T., Murray M., O'Rourke M., Keilty G., Hirst D.G. Modification of vascular tone using iNOS under the control of a radiation-inducible promoter. Gene Ther. 7:2000;1126-1131.
    • (2000) Gene Ther. , vol.7 , pp. 1126-1131
    • Worthington, J.1    Robson, T.2    Murray, M.3    O'Rourke, M.4    Keilty, G.5    Hirst, D.G.6
  • 103
    • 0141538139 scopus 로고    scopus 로고
    • Radiogenetic therapy: Strategies to overcome tumor resistance
    • Marples B., Greco O., Joiner M.C., Scott S.D. Radiogenetic therapy: strategies to overcome tumor resistance. Curr. Pharm. Des. 9:2003;2105-2112.
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 2105-2112
    • Marples, B.1    Greco, O.2    Joiner, M.C.3    Scott, S.D.4
  • 104
    • 0034280568 scopus 로고    scopus 로고
    • Gene therapy of rat medullary thyroid cancer by naked nitric oxide synthase II DNA injection
    • Soler M.N., Bobe P., Benihoud K., Lemaire G., Roos B.A., Lausson S. Gene therapy of rat medullary thyroid cancer by naked nitric oxide synthase II DNA injection. J. Gene Med. 2:2000;344-352.
    • (2000) J. Gene Med. , vol.2 , pp. 344-352
    • Soler, M.N.1    Bobe, P.2    Benihoud, K.3    Lemaire, G.4    Roos, B.A.5    Lausson, S.6
  • 105
    • 85047697705 scopus 로고    scopus 로고
    • Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: A novel suicide gene therapy
    • Worthington J., Robson T., O'Keeffe M., Hirst D.G. Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: a novel suicide gene therapy. Gene Ther. 9:2002;263-269.
    • (2002) Gene Ther. , vol.9 , pp. 263-269
    • Worthington, J.1    Robson, T.2    O'Keeffe, M.3    Hirst, D.G.4
  • 106
    • 0042326321 scopus 로고    scopus 로고
    • Technology evaluation: TNFerade, GenVec
    • Kircheis R., Wagner E. Technology evaluation: TNFerade, GenVec. Curr. Opin. Mol. Ther. 5:2003;437-447.
    • (2003) Curr. Opin. Mol. Ther. , vol.5 , pp. 437-447
    • Kircheis, R.1    Wagner, E.2
  • 107
    • 0842278333 scopus 로고    scopus 로고
    • Radiation therapy: Activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology
    • Kufe D., Weichselbaum R. Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology. Cancer Biol. Ther. 2:2003;326-329.
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 326-329
    • Kufe, D.1    Weichselbaum, R.2
  • 108
    • 0035940408 scopus 로고    scopus 로고
    • Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts
    • Khodarev N.N., Park J.O., Yu J., Gupta N., Nodzenski E., Roizman B., Weichselbaum R.R. Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts. Proc. Natl. Acad. Sci. U.S.A. 98:2001;12665-12670.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 12665-12670
    • Khodarev, N.N.1    Park, J.O.2    Yu, J.3    Gupta, N.4    Nodzenski, E.5    Roizman, B.6    Weichselbaum, R.R.7
  • 109
    • 0141785046 scopus 로고    scopus 로고
    • Functional genomics as a window on radiation stress signaling
    • Amundson S.A., Bittner M., Fornace A.J. Jr. Functional genomics as a window on radiation stress signaling. Oncogene. 22:2003;5828-5833.
    • (2003) Oncogene , vol.22 , pp. 5828-5833
    • Amundson, S.A.1    Bittner, M.2    Fornace Jr., A.J.3


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