Leptin induces endothelial cell migration through Akt, which is inhibited by PPARγ-ligands

Hypertension

Volumn 40, Issue 5, 2002, Pages 748-754

  Goetze, Stephan ^a   Bungenstock, Anne ^a   Czupalla, Cornelia ^a   Eilers, Friedrich ^a   Stawowy, Philipp ^a   Kintscher, Ulrich ^a   Spencer Hänsch, Chantel ^a   Graf, Kristof ^a   Nürnberg, Bernd ^a   Law, Ronald E ^a   Fleck, Eckart ^a   Gräfe, Michael ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

Author keywords

Diabetes mellitus; Endothelium; Kinase; Phosphorylation; Signal transduction; Vasculature

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; CIGLITAZONE; LEPTIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TROGLITAZONE; WORTMANNIN;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC ANGIOPATHY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERINSULINEMIA; NEOVASCULARIZATION (PATHOLOGY); OBESITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ANDROSTADIENES; CELL LINE; CELL MOVEMENT; CHEMOTAXIS; CHROMANS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; HUMANS; LEPTIN; LIGANDS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0036840309     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000035522.63647.D3     Document Type: Article

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