-
1
-
-
0031057517
-
Transcriptional activation by peroxisome proliferator- Activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
-
Adams, M., Reginato, M.J., Shao, D., Lazar, M.A., and Chatterjee, V.K. (1997). Transcriptional activation by peroxisome proliferator- Activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J. Biol. Chem. 272, 5128-5132.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5128-5132
-
-
Adams, M.1
Reginato, M.J.2
Shao, D.3
Lazar, M.A.4
Chatterjee, V.K.5
-
2
-
-
0031595670
-
Activation of ppargamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells
-
Brockman, J.A., Gupta, R.A., and Dubois, R.N. (1998). Activation of ppargamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 115, 1049-1055.
-
(1998)
Gastroenterology
, vol.115
, pp. 1049-1055
-
-
Brockman, J.A.1
Gupta, R.A.2
Dubois, R.N.3
-
3
-
-
0032428151
-
Modeling stochastic gene expression: Implications for haploinsufficiency
-
Cook, D.L., Gerber, A.N., and Tapscott, S.J. (1998). Modeling stochastic gene expression: Implications for haploinsufficiency. Proc. Natl. Acad. Sci. USA 95, 15641-15646.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15641-15646
-
-
Cook, D.L.1
Gerber, A.N.2
Tapscott, S.J.3
-
4
-
-
0033616795
-
Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma
-
Demetri, G.D., Fletcher, C.D., Mueller, E., Sarraf, P., Naujoks, R., Campbell, N., Spiegelman, B.M., and Singer, S. (1999). Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. Proc. Natl. Acad. Sci. USA 96, 3951-3956.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3951-3956
-
-
Demetri, G.D.1
Fletcher, C.D.2
Mueller, E.3
Sarraf, P.4
Naujoks, R.5
Campbell, N.6
Spiegelman, B.M.7
Singer, S.8
-
5
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
Elstner, E., Muller, C., Koshizuka, K., Williamson, E.A., Park, D., Asou, H., Shintaku, P., Said, J.W., Heber, D., and Koeffler, H.P. (1998). Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc. Natl. Acad. Sci. USA 95, 8806-8811
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
Williamson, E.A.4
Park, D.5
Asou, H.6
Shintaku, P.7
Said, J.W.8
Heber, D.9
Koeffler, H.P.10
-
6
-
-
0032894774
-
RET proto-oncogene in the development of human cancer
-
Eng, C. (1999). RET proto-oncogene in the development of human cancer. J. Clin. Oncol. 17, 380-393.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 380-393
-
-
Eng, C.1
-
7
-
-
0031136141
-
Third international workshop on collaborative interdisciplinary studies of p53 and other predisposing genes in li-fraumeni syndrome
-
Eng, C., Schneider, K., Fraumeni, J.F., and Li, F.P. (1997). Third international workshop on collaborative interdisciplinary studies of p53 and other predisposing genes in li-fraumeni syndrome. Cancer Epidemiol. Biomarkers Prev. 6, 379-383.
-
(1997)
Cancer Epidemiol. Biomarkers Prev.
, vol.6
, pp. 379-383
-
-
Eng, C.1
Schneider, K.2
Fraumeni, J.F.3
Li, F.P.4
-
8
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E.R., and Vogelstein, B. (1992). A genetic model for colorectal tumorigenesis. Cell 61, 759-767.
-
(1992)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
10
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt, M.S., Bennett, W.P., Hollstein, M., and Harris, C.C. (1994). Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res. 54, 4855-4878.
-
(1994)
Cancer Res.
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
11
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of ppargamma
-
Hu, E., Kim, J.B., Sarraf, P., and Spiegelman, B.M. (1996). Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of ppargamma. Science 274, 2100-2103.
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
12
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K.W., and Vogelstein, B. (1996). Lessons from hereditary colorectal cancer. Cell 87, 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
13
-
-
0028972026
-
A prostaglandin j2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
-
Kliewer, S.A., Lenhard, J.M., Willson, T.M., Patel, I., Morris, D.C., and Lehmann, J.M. (1995). A prostaglandin j2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83, 813-819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehmann, J.M.6
-
14
-
-
0032145363
-
Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
-
Kubota, T., Koshizuka, K., Williamson, E.A., Asou, H., Said, J.W., Holden, S., Miyoshi, I., and Koeffler, H.P. (1998). Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res. 58, 3344-3352.
-
(1998)
Cancer Res.
, vol.58
, pp. 3344-3352
-
-
Kubota, T.1
Koshizuka, K.2
Williamson, E.A.3
Asou, H.4
Said, J.W.5
Holden, S.6
Miyoshi, I.7
Koeffler, H.P.8
-
15
-
-
0031694577
-
Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in c57bl/6j-apcmin/+ mice
-
Levebvre, A.-M., Chen, I., Desreumaux, P., Najib, N., Fruchart, J.-C., Geboes, K., Briggs, M.,Heyman, R.,and Auwerx, J. (1998). Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in c57bl/6j-apcmin/+ mice. Nat. Med. 4, 1053-1056.
-
(1998)
Nat. Med.
, vol.4
, pp. 1053-1056
-
-
Levebvre, A.-M.1
Chen, I.2
Desreumaux, P.3
Najib, N.4
Fruchart, J.-C.5
Geboes, K.6
Briggs, M.7
Heyman, R.8
Auwerx, J.9
-
16
-
-
0031004088
-
Germline mutations of the PTEN gene in cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., Marsh, D.J., Li, J., Dahia, P.L. M., Wang, S.I., Zheng, Z., Bose, S., Call, K.M., Tsou, H.C., Peacocke, M., et al. (1997). Germline mutations of the PTEN gene in cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16, 64-67.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
-
17
-
-
6844252284
-
Mutation spectrum and genotype-phenotype analyses in cowden disease and bannayan-zonana syndrome, two hamartoma syndromes with germline PTEN mutation
-
Marsh, D.J., Coulon, V., Lunetta, K.L., Rocca-Serra, P., Dahia, P.L.M., Zheng, Z., Liaw, D., Caron, S., Duboué, B., Lin, A.Y., et al. (1998a). Mutation spectrum and genotype-phenotype analyses in cowden disease and bannayan-zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum. Mol. Genet. 7, 507-515.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 507-515
-
-
Marsh, D.J.1
Coulon, V.2
Lunetta, K.L.3
Rocca-Serra, P.4
Dahia, P.L.M.5
Zheng, Z.6
Liaw, D.7
Caron, S.8
Duboué, B.9
Lin, A.Y.10
-
18
-
-
0031974752
-
Allelic imbalance, including deletion of PTEN/MMAC1, at the cowden disease locus on 10q22-23, in hamartomas from patients with cowden syndrome and germline PTEN mutation
-
Marsh, D.J., Dahia, P.L. M., Coulon, V., Zheng, Z., Dorion-Bonnet, F., Call, K.M., Little, R., Lin, A.Y., Eeles, R.A., Goldstein, A.M., et al. (1998b). Allelic imbalance, including deletion of PTEN/MMAC1, at the cowden disease locus on 10q22-23, in hamartomas from patients with cowden syndrome and germline PTEN mutation. Genes Chromosomes Cancer 21, 61-69.
-
(1998)
Genes Chromosomes Cancer
, vol.21
, pp. 61-69
-
-
Marsh, D.J.1
Dahia, P.L.M.2
Coulon, V.3
Zheng, Z.4
Dorion-Bonnet, F.5
Call, K.M.6
Little, R.7
Lin, A.Y.8
Eeles, R.A.9
Goldstein, A.M.10
-
19
-
-
0031993322
-
Terminal differentiation of human breast cancer through pparγ
-
Mueller, E., Sarraf, P., Tontonoz, P., Evans, R.M., Martin, K.J., Zhang, M., Fletcher, C., Singer, S., and Spiegelman, B.M. (1998). Terminal differentiation of human breast cancer through pparγ. Mol. Cell 1, 465-470.
-
(1998)
Mol. Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
Evans, R.M.4
Martin, K.J.5
Zhang, M.6
Fletcher, C.7
Singer, S.8
Spiegelman, B.M.9
-
20
-
-
0032540325
-
Oxidised LDL regulates macrophage gene expression through ligand activation of pparγ
-
Nagy, L., Tontonoz, P., Alvarez, J.G.A., Chen, H., and Evans, R.M. (1998). Oxidised LDL regulates macrophage gene expression through ligand activation of pparγ. Cell 93, 229-240.
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.A.3
Chen, H.4
Evans, R.M.5
-
21
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor γ
-
Nolte, R.T., Wisely, G.B., Westin, S., Cobb, J.E., Lambert, M.H., Kurokawa, R., Rosenfeld, M.G., Willson, T.M., Glass, C.K., and MilBurn, M.V. (1998). Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor γ. Nature 395, 137-143.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
Kurokawa, R.6
Rosenfeld, M.G.7
Willson, T.M.8
Glass, C.K.9
Milburn, M.V.10
-
22
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
Ricote, M., Li, A.C., Willson, T.M., Kelly, C.J., and Glass, C.K. (1998) The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391, 79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
23
-
-
0032189782
-
Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
-
Ristow, M., Muller-Wieland, D., Pfeiffer, A., Krone, W., and Kahn, C.R. (1998). Obesity associated with a mutation in a genetic regulator of adipocyte differentiation. N. Engl. J. Med. 339, 953-959.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 953-959
-
-
Ristow, M.1
Muller-Wieland, D.2
Pfeiffer, A.3
Krone, W.4
Kahn, C.R.5
-
24
-
-
0031667938
-
Activators of the nuclear receptor pparγ enhance colon polyp formation
-
Saez, E., Tontonoz, P., Nelson, M.C., Alvarez, J.G.A., Tze, M.U., Baird, S.M., Thomazy, V.A., and Evans, R.M. (1998). Activators of the nuclear receptor pparγ enhance colon polyp formation. Nat. Med. 4, 1058-1061.
-
(1998)
Nat. Med.
, vol.4
, pp. 1058-1061
-
-
Saez, E.1
Tontonoz, P.2
Nelson, M.C.3
Alvarez, J.G.A.4
Tze, M.U.5
Baird, S.M.6
Thomazy, V.A.7
Evans, R.M.8
-
25
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through pparγ
-
Sarraf, P., Mueller, E., Jones, D., King, F.J., Deangelo, D.J., ParTridge, J.B., Holden, S.A., Chen, L.B., Singer, S., Fletcher, C., and Spiegelman, B.M. (1998). Differentiation and reversal of malignant changes in colon cancer through pparγ. Nat. Med. 4, 1046-1052.
-
(1998)
Nat. Med.
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
King, F.J.4
Deangelo, D.J.5
Partridge, J.B.6
Holden, S.A.7
Chen, L.B.8
Singer, S.9
Fletcher, C.10
Spiegelman, B.M.11
-
26
-
-
0031898610
-
Ppargamma: Adipogenic regulator and thiazolidinedione receptor
-
Spiegelman, B.M. (1998). Ppargamma: Adipogenic regulator and thiazolidinedione receptor. Diabetes 47, 507-514.
-
(1998)
Diabetes
, vol.47
, pp. 507-514
-
-
Spiegelman, B.M.1
-
27
-
-
0032540012
-
Pparγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz, P., Nagy, L., Alvarez, J.G., Thomazy, V.A., and Evans, R.M. (1998). Pparγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93, 241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
Thomazy, V.A.4
Evans, R.M.5
-
28
-
-
0032555236
-
Signaling pathways in ras-mediated tumorigenecity and metastases
-
Webb, C.P., van Aelst, L., Wigler, M.H., and van der Woude, G.f. (1998). Signaling pathways in ras-mediated tumorigenecity and metastases. Proc. Natl. Acad. Sci. USA 95, 8773-8778.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8773-8778
-
-
Webb, C.P.1
Van Aelst, L.2
Wigler, M.H.3
Van Der, W.4
|