-
1
-
-
0035851187
-
PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen, E.D., and Spiegelman, B.M. 2001. PPARγ: a nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 276:37731-37734.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
2
-
-
0033213637
-
PPAR-γ is required for placental, cardiac, and adipose tissue development
-
Barak, Y., et al. 1999. PPAR-γ is required for placental, cardiac, and adipose tissue development. Mol. Cell. 4:585-595.
-
(1999)
Mol. Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
-
3
-
-
0028641559
-
Stimulation ofadipogenesis in fibroblasts by PPARγ 2, a lipid activated transcription factor
-
Tontonoz, P., Hu, E., and Spiegelman, B.M. 1994. Stimulation ofadipogenesis in fibroblasts by PPARγ 2, a lipid activated transcription factor. Cell. 79:1147-1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
4
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz, P., Nagy, L., Alvarez, J.G., Thomazy, V.A., and Evans, R.M. 1998. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
Thomazy, V.A.4
Evans, R.M.5
-
5
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPARγ
-
Mueller, E., et al. 1998. Terminal differentiation of human breast cancer through PPARγ. Mol. Cell. 1:465-470.
-
(1998)
Mol. Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
-
6
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARγ
-
Sarraf, P., et al. 1998. Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nat. Med. 4:1046-1052.
-
(1998)
Nat. Med.
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
-
7
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor
-
Tontonoz, P., et al. 1991. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor. Proc. Natl. Acad. Sci. USA. 94:237-241.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
-
8
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor γ and retinoic acid and receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
Elstner, E., et al. 1998. Ligands for peroxisome proliferator-activated receptor γ and retinoic acid and receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc. Natl. Acad. Sci. USA. 95:8806-8811.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
-
9
-
-
0032145363
-
Ligand for peroxisome-activated receptor γ (Troglitazone) has potent antitumor effect against human prostate cancer both in vivo and in vitro
-
Kubota, T., et al. 1998 Ligand for peroxisome-activated receptor γ (Troglitazone) has potent antitumor effect against human prostate cancer both in vivo and in vitro. Cancer Res. 58:3344-3352.
-
(1998)
Cancer Res.
, vol.58
, pp. 3344-3352
-
-
Kubota, T.1
-
10
-
-
0034880165
-
Role of peroxisome proliferator-activated receptor γ and its ligands in non-neoplastic and neoplastic human urothelial cells
-
Nakashiro, K., et al. 2001. Role of peroxisome proliferator-activated receptor γ and its ligands in non-neoplastic and neoplastic human urothelial cells. Am. J. Pathol. 159:591-597.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 591-597
-
-
Nakashiro, K.1
-
11
-
-
0035019640
-
Ligands for peroxisome proliferator-activated receptor γ inhibit growth and induce apoprosis of human papillary thyroid carcinoma cells
-
Ohta, K., Endo, T., Haraguchi, K., Hershman, J.M., and Onaya, T. 2001. Ligands for peroxisome proliferator-activated receptor γ inhibit growth and induce apoprosis of human papillary thyroid carcinoma cells. J. Clin. Endocrinol Metab. 86:2170-2177.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2170-2177
-
-
Ohta, K.1
Endo, T.2
Haraguchi, K.3
Hershman, J.M.4
Onaya, T.5
-
12
-
-
0035881317
-
Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation
-
Palakurthi, S.S., Aktas, H., Grubissich, L.M., Mortensen, R.M., and Halperin, J.A. 2001. Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation. Cancer Res. 61:6213-6218.
-
(2001)
Cancer Res.
, vol.61
, pp. 6213-6218
-
-
Palakurthi, S.S.1
Aktas, H.2
Grubissich, L.M.3
Mortensen, R.M.4
Halperin, J.A.5
-
13
-
-
0001123485
-
Tumor angiogenesis
-
J.F. Holland et al., editors. B.C. Decker Inc. Hamilton, Ontario, Canada
-
Folkman, J. 2000. Tumor angiogenesis. In Cancer medicine. 5th edition. J.F. Holland et al., editors. B.C. Decker Inc. Hamilton, Ontario, Canada. 132-152.
-
(2000)
Cancer medicine. 5th edition
, pp. 132-152
-
-
Folkman, J.1
-
14
-
-
0032587328
-
PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARγ as a potential mediator in vascular disease
-
Marx, N., Bourcier, T., Sukhova, G.K., Libby, P., and Plutzky, J. 1999. PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARγ as a potential mediator in vascular disease. Arterioscler Thromb. Vasc. Biol. 19:546-551.
-
(1999)
Arterioscler Thromb. Vasc. Biol.
, vol.19
, pp. 546-551
-
-
Marx, N.1
Bourcier, T.2
Sukhova, G.K.3
Libby, P.4
Plutzky, J.5
-
15
-
-
0033605677
-
Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo
-
Xin, X., Yang, S., Kowalskij, and Gerritsen, M.E. 1999. Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo. J. Biol. Chem. 274:9116-9121.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9116-9121
-
-
Xin, X.1
Yang, S.2
Kowalski, J.3
Gerritsen, M.E.4
-
17
-
-
0031750208
-
Effects of troglirazone and pioglitazone on cytokine-mediated endothelial cell proliferation in vitro
-
Gralinski, M.R., Rowse, P.E., and Breider, M.A. 1998. Effects of troglirazone and pioglitazone on cytokine-mediated endothelial cell proliferation in vitro. J. Cardiovasc. Pharmacol. 31:909-913.
-
(1998)
J. Cardiovasc. Pharmacol.
, vol.31
, pp. 909-913
-
-
Gralinski, M.R.1
Rowse, P.E.2
Breider, M.A.3
-
18
-
-
2142701648
-
Peroxisome proliferator-activated receptor-γ ligands inhibit choroidal neovascularization
-
Murata, T., et al. 2000. Peroxisome proliferator-activated receptor-γ ligands inhibit choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 41:2309-2317.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 2309-2317
-
-
Murata, T.1
-
19
-
-
0035156236
-
Expression of peroxisome proliferator-activated receptor (PPAR)-gamma in human lung cancer
-
Inoue, K., et al. 2001. Expression of peroxisome proliferator-activated receptor (PPAR)-gamma in human lung cancer. Anticancer Res. 21:2471-2476.
-
(2001)
Anticancer Res.
, vol.21
, pp. 2471-2476
-
-
Inoue, K.1
-
20
-
-
0032719528
-
Interferon-α-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule
-
Slaron, J.W., Perrotte, P., Inoue, K., Dinney, C., and Fidler, I.J. 1999. Interferon-α-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule. Clin. Cancer Res. 5:2726-2734.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2726-2734
-
-
Slaron, J.W.1
Perrotte, P.2
Inoue, K.3
Dinney, C.4
Fidler, I.J.5
-
21
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato, R., Loughnan, M.S., Flynn, E., and Folkman, J. 1994. Thalidomide is an inhibitor of angiogenesis. Proc. Natl. Acad. Sci. USA. 91:4082-4085.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4082-4085
-
-
D'Amato, R.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
22
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxgenase-2 inhibitors
-
Masferrer, J.L., et al. 2000 Antiangiogenic and antitumor activities of cyclooxgenase-2 inhibitors. Cancer Res. 60:1306-1311.
-
(2000)
Cancer Res.
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
-
23
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma
-
O'Reilly, M.S., et al 1994. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma. Cell. 79:315-328.
-
(1994)
Cell
, vol.79
, pp. 315-328
-
-
O'Reilly, M.S.1
-
24
-
-
0026652533
-
Metastatic model for human prostate cancer using orthoropic implantation in nude mice
-
Stephenson, R.A., et al. 1992. Metastatic model for human prostate cancer using orthoropic implantation in nude mice. J. Natl. Cancer Inst. 84:951-957.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 951-957
-
-
Stephenson, R.A.1
-
25
-
-
0028306887
-
Retinoids modulate endothelial cell production of matrix-degrading proteases and tissue inhibitors of metalloproteinases (TIMP)
-
Braunhut, S., and Moses, M. 1994. Retinoids modulate endothelial cell production of matrix-degrading proteases and tissue inhibitors of metalloproteinases (TIMP). J. Biol. Chem. 269:13472-13479.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13472-13479
-
-
Braunhut, S.1
Moses, M.2
-
26
-
-
0025351278
-
Identification of an inhibitor of neovascularization from cartilage
-
Moses, M.A., Sudhalter, J., and Langer, R. 1990. Identification of an inhibitor of neovascularization from cartilage. Science. 248:1408-1410.
-
(1990)
Science
, vol.248
, pp. 1408-1410
-
-
Moses, M.A.1
Sudhalter, J.2
Langer, R.3
-
27
-
-
0034674567
-
Degradation of the peroxisome proliferator-activated receptor γ is linked to ligand dependent activation
-
Hauser, S., et al. 2000. Degradation of the peroxisome proliferator-activated receptor γ is linked to ligand dependent activation. J. Biol. Chem. 275:18527-18533.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18527-18533
-
-
Hauser, S.1
-
28
-
-
13044311402
-
Troponin I is present in human cartilage and inhibits angiogenesis
-
Moses, M.A., et al. 1999. Troponin I is present in human cartilage and inhibits angiogenesis. Proc. Natl. Acad. Sci. USA. 96:2645-2650.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2645-2650
-
-
Moses, M.A.1
-
29
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
Browder, T., et al. 2000. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res. 60:1878-1886.
-
(2000)
Cancer Res.
, vol.60
, pp. 1878-1886
-
-
Browder, T.1
-
30
-
-
0036183630
-
Mechanism of action of PPARs
-
Berger, J., and Moller, D.E. 2002. Mechanism of action of PPARs. Annu. Rev. Med. 53:409-435.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
31
-
-
0034232194
-
The chick embryo chorioallantoic membrane as a model for in vivo research on antiangiogenesis
-
Ribatti, D., Vacca, A., Roncali, L., and Dammacco, F. 2000 The chick embryo chorioallantoic membrane as a model for in vivo research on antiangiogenesis. Curr. Pharm. Biotechnol. 1:73-82.
-
(2000)
Curr. Pharm. Biotechnol.
, vol.1
, pp. 73-82
-
-
Ribatti, D.1
Vacca, A.2
Roncali, L.3
Dammacco, F.4
-
32
-
-
0035211504
-
Angiogenesis-dependent diseases
-
Folkman, J. 2001. Angiogenesis-dependent diseases. Semin. Oncol. 28:536-542.
-
(2001)
Semin. Oncol.
, vol.28
, pp. 536-542
-
-
Folkman, J.1
-
33
-
-
0037134709
-
Clinical application of antiangiogenic therapy: Microvessel density, what it does and does not tell us
-
Hlatky, L., Hahnfeldt, P., and Folkman, J. 2002. Clinical application of antiangiogenic therapy: microvessel density, what it does and does not tell us. J. Natl. Cancer Inst. 94:883-893.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 883-893
-
-
Hlatky, L.1
Hahnfeldt, P.2
Folkman, J.3
-
34
-
-
0032170033
-
Centrosome defects and genetic instability in malignant minors
-
Pihan, G.A., et al. 1998. Centrosome defects and genetic instability in malignant minors. Cancer Res. 58:3974-3985.
-
(1998)
Cancer Res.
, vol.58
, pp. 3974-3985
-
-
Pihan, G.A.1
-
35
-
-
0030590074
-
Molecular cloning, expression and characterizasion of human peroxisome proliferator activated receptors γ1 and γ2
-
Elbrecht, A., et al. 1996. Molecular cloning, expression and characterizasion of human peroxisome proliferator activated receptors γ1 and γ2. Biochem. Biophys. Res. Commun. 224:431-437.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.224
, pp. 431-437
-
-
Elbrecht, A.1
-
36
-
-
0033002651
-
Systemic exposure to rosiglitazone is unaltered by food
-
Freed, M.I., Allen, A., Jorkasky, D.K., and DiCicco, R.A. 1999. Systemic exposure to rosiglitazone is unaltered by food. Eur. J. Clin. Pharmacol. 55:53-56
-
(1999)
Eur. J. Clin. Pharmacol.
, vol.55
, pp. 53-56
-
-
Freed, M.I.1
Allen, A.2
Jorkasky, D.K.3
DiCicco, R.A.4
-
37
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
Sietta-Honigmann, M.R., et al. 1998. Biological action of leptin as an angiogenic factor. Science. 281:1683-1686.
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sietta-Honigmann, M.R.1
-
38
-
-
0033974302
-
Maspin is an angiogenesis inhibitor
-
Zhang, M., Volpert, O., Shi, Y.H., and Bouck, N. 2000. Maspin is an angiogenesis inhibitor. Nat. Med. 6:196-199.
-
(2000)
Nat. Med.
, vol.6
, pp. 196-199
-
-
Zhang, M.1
Volpert, O.2
Shi, Y.H.3
Bouck, N.4
-
39
-
-
0342445431
-
Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
-
Jimenez, B., et al. 2000. Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat. Med. 6:41-48.
-
(2000)
Nat. Med.
, vol.6
, pp. 41-48
-
-
Jimenez, B.1
-
40
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa, S., et al. 2002. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J. Pathol. 160:985-1000.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
-
41
-
-
0028331285
-
Macrophages and angiogenesis
-
Sunderkotter, C., Steinbrink, K., Goebeler, M., Bhardwaj, R., and Sorg, C. 1994. Macrophages and angiogenesis. J. Leukoc. Biol 55:410-422.
-
(1994)
J. Leukoc. Biol.
, vol.55
, pp. 410-422
-
-
Sunderkotter, C.1
Steinbrink, K.2
Goebeler, M.3
Bhardwaj, R.4
Sorg, C.5
-
42
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote, M., Li, A.C., Willson, T.M., Kelly, C.J., and Glass, C.K. 1998. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation Nature 391:79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
43
-
-
0034711678
-
Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators
-
Pasceri, V., Wu, H.D., Willerson, J.T., and Yeh, E.T.H. 2000. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators. Circulation. 101:235-238.
-
(2000)
Circulation
, vol.101
, pp. 235-238
-
-
Pasceri, V.1
Wu, H.D.2
Willerson, J.T.3
Yeh, E.T.H.4
-
44
-
-
0343293956
-
Continuous administration of angiostatin inhibits accelerated growth of colorectal liver metastases after partial hepasectomy
-
Drixler, T.A., et al. 2000. Continuous administration of angiostatin inhibits accelerated growth of colorectal liver metastases after partial hepasectomy. Cancer Res. 60:1761-1765
-
(2000)
Cancer Res.
, vol.60
, pp. 1761-1765
-
-
Drixler, T.A.1
-
45
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained rumor regression without overt toxicity
-
Klement, G., et al. 2000. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained rumor regression without overt toxicity. J. Clin. Invest. 105:15-24.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 15-24
-
-
Klement, G.1
-
46
-
-
0034889267
-
Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells
-
Clay, C.E., et al. 2001. Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells. J Investig. Med. 49:413-420.
-
(2001)
J. Investig. Med.
, vol.49
, pp. 413-420
-
-
Clay, C.E.1
-
47
-
-
0026027556
-
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
-
Liotta, L.A., Steeg, P.S., and Stetler-Stevenson, W.G. 1991. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell. 64:327-336.
-
(1991)
Cell
, vol.64
, pp. 327-336
-
-
Liotta, L.A.1
Steeg, P.S.2
Stetler-Stevenson, W.G.3
-
48
-
-
0036006943
-
PPARγ ligands as modulators of inflammatory and catabolic responses in arthritis. An overview
-
Fahmi, H., Pelletier, J.P., and Martel-Pelletier, J. 2002. PPARγ ligands as modulators of inflammatory and catabolic responses in arthritis. An overview. J. Rheumatol. 29:3-14.
-
(2002)
J. Rheumatol.
, vol.29
, pp. 3-14
-
-
Fahmi, H.1
Pelletier, J.P.2
Martel-Pelletier, J.3
|