Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: A new model for anti-estrogen resistance

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 9817-9824

  Campbell, Robert A ^a   Bhat Nakshatri, Poornima ^a   Patel, Nikhil M ^a   Constantinidou, Demetra ^b   Ali, Simak ^b   Nakshatri, Harikrishna ^a,c  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME KINETICS; GENES; HORMONES; MEDICAL PROBLEMS; TUMORS;

PHOSPHORYLATION;

ENZYMES;

2 MORPHOLINO 8 PHENYLCHROMONE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; MACROPHAGE MIGRATION INHIBITION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN AF 1; PROTEIN AF 2; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN PS2; SERINE; TAMOXIFEN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; AKT1 PROTEIN, HUMAN; ANTIESTROGEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; CHLORAMPHENICOL ACETYLTRANSFERASE; CHROMONE DERIVATIVE; CYTOKINE; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE; ONCOPROTEIN; PHOSPHATASE; PHOSPHATE; PLAB PROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE; PTEN PROTEIN, HUMAN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TFF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER INHIBITION; ENDOMETRIUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ESTROGEN ACTIVITY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; ANIMAL; BIOLOGICAL MODEL; BREAST TUMOR; CELL CULTURE; CELL DIVISION; CELL STRAIN COS1; CELL SURVIVAL; DRUG EFFECT; DRUG RESISTANCE; GENETIC TRANSFECTION; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PLASMID; SERODIAGNOSIS; SIGNAL TRANSDUCTION; TIME; UPREGULATION; WESTERN BLOTTING;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL DIVISION; CELL SURVIVAL; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CHROMONES; COS CELLS; CYTOKINES; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; ENZYME INHIBITORS; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; HUMANS; MODELS, BIOLOGICAL; MORPHOLINES; PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PTEN PHOSPHOHYDROLASE; RECEPTORS, ESTROGEN; SERINE; SIGNAL TRANSDUCTION; TAMOXIFEN; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 0035971181     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010840200     Document Type: Article

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