메뉴 건너뛰기




Volumn 87, Issue 11, 2008, Pages 992-1003

siRNA, miRNA, and shRNA: In vivo applications

Author keywords

Caenorhabditis elegans; Gene silencing; In vivo; microRNAs; RNA activation; RNA interference; Short hairpin RNAs; Small interfering RNAs

Indexed keywords

MICRORNA; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA;

EID: 58149242904     PISSN: 00220345     EISSN: None     Source Type: Journal    
DOI: 10.1177/154405910808701109     Document Type: Article
Times cited : (101)

References (135)
  • 1
    • 34248682403 scopus 로고    scopus 로고
    • RNAi therapcutics: Principles, prospects and challenges
    • Aagaard L, Rossi JJ (2007). RNAi therapcutics: principles, prospects and challenges. Adv Drug Deliv Rev 59:75-86.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 75-86
    • Aagaard, L.1    Rossi, J.J.2
  • 2
    • 0037440005 scopus 로고    scopus 로고
    • Tolerance for mutations and chemical modifications in a siRNA
    • Amarzguioui M, Holen T, Babaie E, Prydz H (2003), Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res 31:589-595.
    • (2003) Nucleic Acids Res , vol.31 , pp. 589-595
    • Amarzguioui, M.1    Holen, T.2    Babaie, E.3    Prydz, H.4
  • 3
    • 64149108725 scopus 로고    scopus 로고
    • The functions of animal microRNAs, Nature 431:350-Azzouz M (2006). Gene therapy for ALS: Progress and prospects
    • Ambros V (2004). The functions of animal microRNAs, Nature 431:350-Azzouz M (2006). Gene therapy for ALS: progress and prospects. Biochim Biophys Acta 1762:1122-1127.
    • (2004) Biochim Biophys Acta , vol.1762 , pp. 1122-1127
    • Ambros, V.1
  • 4
    • 0018352913 scopus 로고
    • Interferon-induced enzymatic activities and their role in the antriviral state
    • Baglioni C (1979). Interferon-induced enzymatic activities and their role in the antriviral state. Cell 17:255-264.
    • (1979) Cell , vol.17 , pp. 255-264
    • Baglioni, C.1
  • 5
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 6
    • 0031061733 scopus 로고    scopus 로고
    • The periodontal ligament: A unique, multifunctional connective tissue
    • Beertsen W, McCulloch CA, Sodek J (1997). The periodontal ligament: a unique, multifunctional connective tissue. Periodontal 2000 13:20-40.
    • (1997) Periodontal 2000 , vol.13 , pp. 20-40
    • Beertsen, W.1    McCulloch, C.A.2    Sodek, J.3
  • 8
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon OJ (2001a). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, O.J.4
  • 11
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-+ dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack MT, Czaplinski K, Gorlich D (2004). Exportin 5 is a RanGTP-+ dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10:185-191.
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 12
    • 33747876113 scopus 로고    scopus 로고
    • Calin GA, Croce CM (2006a). MicroRNA-cancer connection: the beginning of a new tale. Cancer Res 66:7390-7394. Calin GA, Croee CM (2006b). MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866.
    • Calin GA, Croce CM (2006a). MicroRNA-cancer connection: the beginning of a new tale. Cancer Res 66:7390-7394. Calin GA, Croee CM (2006b). MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866.
  • 13
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of miero-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitm CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. (2002). Frequent deletions and down-regulation of miero-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99:15524-15529.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitm, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 14
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, et al. (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101:2999-3004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5    Yendamuri, S.6
  • 15
    • 0035859929 scopus 로고    scopus 로고
    • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    • Caplen NJ, Parrish S, Imani F, Fire A, Morgan RA (2001). Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci USA 98:9742-9747.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9742-9747
    • Caplen, N.J.1    Parrish, S.2    Imani, F.3    Fire, A.4    Morgan, R.A.5
  • 16
    • 33747754760 scopus 로고    scopus 로고
    • Lessons from nature: MicroRNA-based shRNA libraries
    • Chang K, Elledge SJ, Hannon GJ (2006). Lessons from nature: microRNA-based shRNA libraries. Nat Methods 3:707-714.
    • (2006) Nat Methods , vol.3 , pp. 707-714
    • Chang, K.1    Elledge, S.J.2    Hannon, G.J.3
  • 17
    • 34548164577 scopus 로고    scopus 로고
    • RNA interference: Hitting the on switch
    • Cheek E (2007). RNA interference: hitting the on switch. Nature 448:855-858.
    • (2007) Nature , vol.448 , pp. 855-858
    • Cheek, E.1
  • 18
    • 33846309616 scopus 로고    scopus 로고
    • DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis
    • Chen YJ, Chang JT, Lee L, Wang HM, Liao CT, Chiu CC, et al. (2007). DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. Oncogene 26:467-476.
    • (2007) Oncogene , vol.26 , pp. 467-476
    • Chen, Y.J.1    Chang, J.T.2    Lee, L.3    Wang, H.M.4    Liao, C.T.5    Chiu, C.C.6
  • 19
    • 0041331496 scopus 로고    scopus 로고
    • siRNA function in RNAi: A chemical modification analysis
    • Chiu YL, Rana TM (2003). siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-1048.
    • (2003) RNA , vol.9 , pp. 1034-1048
    • Chiu, Y.L.1    Rana, T.M.2
  • 21
    • 36749033738 scopus 로고    scopus 로고
    • Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits
    • DiFiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, et al. (2007). Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci USA 104:17204-17209.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 17204-17209
    • DiFiglia, M.1    Sena-Esteves, M.2    Chase, K.3    Sapp, E.4    Pfister, E.5    Sass, M.6
  • 23
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene fonction in somatic mammalian cells using small interfering RNAs
    • Elbashir SM, Harborth J, Weber K, Tuschl T (2002). Analysis of gene fonction in somatic mammalian cells using small interfering RNAs. Methods 26:199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 24
    • 34248634004 scopus 로고    scopus 로고
    • Therapeutic potential for microRNAs
    • Esau CC, Monia BP (2007). Therapeutic potential for microRNAs. Adv Drug Deliv Rev 59:101-114.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 101-114
    • Esau, C.C.1    Monia, B.P.2
  • 27
    • 0037443035 scopus 로고    scopus 로고
    • Pre-mRNA splicing and human disease
    • Faustino NA, Cooper TA (2003). Pre-mRNA splicing and human disease. Genes Dev 17:419-437.
    • (2003) Genes Dev , vol.17 , pp. 419-437
    • Faustino, N.A.1    Cooper, T.A.2
  • 28
    • 33750031102 scopus 로고    scopus 로고
    • Vector-based RNAi approaches for stable, inducible and genome-wide screens
    • Fewell GD, Schmitt K (2006). Vector-based RNAi approaches for stable, inducible and genome-wide screens. Drug Discov Today 11:975-982.
    • (2006) Drug Discov Today , vol.11 , pp. 975-982
    • Fewell, G.D.1    Schmitt, K.2
  • 29
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 30
    • 39049177605 scopus 로고    scopus 로고
    • Genetics. Small RNAs reveal an activating side
    • Garber K (2006). Genetics. Small RNAs reveal an activating side. Science 314:741-742.
    • (2006) Science , vol.314 , pp. 741-742
    • Garber, K.1
  • 32
    • 44649114578 scopus 로고    scopus 로고
    • Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis
    • Golzio M, Teissie J (2008). Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis. Methods Mol Biol 423:279-287.
    • (2008) Methods Mol Biol , vol.423 , pp. 279-287
    • Golzio, M.1    Teissie, J.2
  • 33
    • 13544265637 scopus 로고    scopus 로고
    • Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery
    • Golzio M, Mazzolini L, Moller P, Rols MP, Teissie J (2005). Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery. Gene Ther 12:246-251.
    • (2005) Gene Ther , vol.12 , pp. 246-251
    • Golzio, M.1    Mazzolini, L.2    Moller, P.3    Rols, M.P.4    Teissie, J.5
  • 35
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posltranscriptional gene silencing
    • Gregory RI, Chcndrimada TP, Cooch N, Shiekhattar R (2005). Human RISC couples microRNA biogenesis and posltranscriptional gene silencing. Cell 123:631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chcndrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 36
    • 26944450901 scopus 로고    scopus 로고
    • RNAi mechanisms in Caenorhabditis elegans
    • Grishok A (2005). RNAi mechanisms in Caenorhabditis elegans. FEBS Lett 579:5932-5939.
    • (2005) FEBS Lett , vol.579 , pp. 5932-5939
    • Grishok, A.1
  • 37
    • 0034737747 scopus 로고    scopus 로고
    • Genetic requirements for inheritance of RNAi in C. elegans
    • Grishok A, Tabara H, Mello CC (2000). Genetic requirements for inheritance of RNAi in C. elegans. Science 287:2494-2497.
    • (2000) Science , vol.287 , pp. 2494-2497
    • Grishok, A.1    Tabara, H.2    Mello, C.C.3
  • 38
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, et al. (2001). Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34.
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6
  • 39
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transeriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D, Hannon GJ (2000). An RNA-directed nuclease mediates post-transeriptional gene silencing in Drosophila cells. Nature 404:293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 40
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN (2004). The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18:3016-3027.
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 41
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ, Rossi JJ (2004). Unlocking the potential of the human genome with RNA interference. Nature 431:371-378.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 42
    • 24344500241 scopus 로고    scopus 로고
    • Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
    • Harborth J, Elbashir SM, Vandenburgh K, Manninga H, Scaringc SA, Weber K, et al. (2003). Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing, Antisense Nucleic Acid Drug Dev 13:83-105.
    • (2003) Antisense Nucleic Acid Drug Dev , vol.13 , pp. 83-105
    • Harborth, J.1    Elbashir, S.M.2    Vandenburgh, K.3    Manninga, H.4    Scaringc, S.A.5    Weber, K.6
  • 43
    • 22144477115 scopus 로고    scopus 로고
    • MicroRNAs in vertebrale development
    • Harfe BD (2005). MicroRNAs in vertebrale development. Curr Opin Genet Dev 15:410-415.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 410-415
    • Harfe, B.D.1
  • 45
    • 33748209616 scopus 로고    scopus 로고
    • Efficient prediction of siRNAs with siRNArulcs 1.0: An open-source JAVA approach to siRNA algorithms
    • Holen T (2006). Efficient prediction of siRNAs with siRNArulcs 1.0: an open-source JAVA approach to siRNA algorithms. RNA 12:1620-1625.
    • (2006) RNA , vol.12 , pp. 1620-1625
    • Holen, T.1
  • 46
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
    • Holen T, Amarzguioui M, Wiiger MT, Babaie E, Prydz H (2002). Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res 30:1757-1766.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3    Babaie, E.4    Prydz, H.5
  • 47
    • 25844450312 scopus 로고    scopus 로고
    • High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA interference in the mouse
    • Hong J, Qian Z, Shen S, Min T, Tan C, Xu J, et al. (2005), High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA interference in the mouse. Biochem J 390(Pt 3):675-679.
    • (2005) Biochem J , vol.390 , Issue.PART 3 , pp. 675-679
    • Hong, J.1    Qian, Z.2    Shen, S.3    Min, T.4    Tan, C.5    Xu, J.6
  • 48
    • 34247581261 scopus 로고    scopus 로고
    • Application of atelocollagen-mediated si RNA delivery for RNAi therapies]
    • article in Japanese
    • Honma K, Takeshita F, Ochiya T (2007). [Application of atelocollagen-mediated si RNA delivery for RNAi therapies]. Yalmgaku Zasshi 127:807-812 [article in Japanese].
    • (2007) Yalmgaku Zasshi , vol.127 , pp. 807-812
    • Honma, K.1    Takeshita, F.2    Ochiya, T.3
  • 49
    • 2342564353 scopus 로고    scopus 로고
    • A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens
    • Hsieh AC, Bo R, Manola J, Vazquez F, Bare O, Khvorova A, et al. (2004). A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens. Nucleic Acids Res 32:893-901.
    • (2004) Nucleic Acids Res , vol.32 , pp. 893-901
    • Hsieh, A.C.1    Bo, R.2    Manola, J.3    Vazquez, F.4    Bare, O.5    Khvorova, A.6
  • 50
    • 1942469322 scopus 로고    scopus 로고
    • Analysis of elathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference
    • Huang F, Khvorova A, Marshall W, Sorkin A (2004). Analysis of elathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem 279:16657-16661.
    • (2004) J Biol Chem , vol.279 , pp. 16657-16661
    • Huang, F.1    Khvorova, A.2    Marshall, W.3    Sorkin, A.4
  • 51
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-? small temporal RNA
    • Hulvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-? small temporal RNA. Science 293:834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hulvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 53
    • 33748337330 scopus 로고    scopus 로고
    • Silencing gene expression by targeting chromosomal DNA with antigene peptide nucleic acids arid duplex RNAs
    • Janowski BA, Hu J, Corey DR (2006). Silencing gene expression by targeting chromosomal DNA with antigene peptide nucleic acids arid duplex RNAs. Nat Protoc 1:436-443.
    • (2006) Nat Protoc , vol.1 , pp. 436-443
    • Janowski, B.A.1    Hu, J.2    Corey, D.R.3
  • 55
    • 36248978183 scopus 로고    scopus 로고
    • Experimental siCD44-targeted therapy of human nasopharyngeal carcinoma mediated by adenovirus]
    • article in Chinese
    • Jod JY, Shi Y, Zhou YQ, Tian Y, Shen L, Liu Y, et al. (2007). [Experimental siCD44-targeted therapy of human nasopharyngeal carcinoma mediated by adenovirus]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 29:626-630 [article in Chinese].
    • (2007) Zhongguo Yi Xue Ke Xue Yuan Xue Bao , vol.29 , pp. 626-630
    • Jod, J.Y.1    Shi, Y.2    Zhou, Y.Q.3    Tian, Y.4    Shen, L.5    Liu, Y.6
  • 56
    • 0024283243 scopus 로고
    • The nematode Caenorhabditis elegans
    • Kenyon C (1988). The nematode Caenorhabditis elegans. Science 240:1448 1453.
    • (1988) Science , vol.240 , pp. 1448-1453
    • Kenyon, C.1
  • 57
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH (2001). Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15:2654-2659.
    • (2001) Genes Dev , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 58
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova A, Reynolds A, Jayasena SD (2003). Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-216.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 60
    • 34249279852 scopus 로고    scopus 로고
    • Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I
    • Kim SI, Shin D, Choi TH, Lee JC, Cheon GJ, Kim KY, et al (2007). Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I. Mol Ther 15:1145-1152.
    • (2007) Mol Ther , vol.15 , pp. 1145-1152
    • Kim, S.I.1    Shin, D.2    Choi, T.H.3    Lee, J.C.4    Cheon, G.J.5    Kim, K.Y.6
  • 61
    • 18344373363 scopus 로고    scopus 로고
    • Small RNAs: Classification, biogenesis, and function
    • Kim VN (2005). Small RNAs: classification, biogenesis, and function. Mol Cells 19:1-15.
    • (2005) Mol Cells , vol.19 , pp. 1-15
    • Kim, V.N.1
  • 62
    • 33746863376 scopus 로고    scopus 로고
    • Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma
    • Kim WJ, Christensen LV, Jo S, Yockman JW, Jeong JH, Kim YH, et al. (2006). Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma. Mol Ther 14:343-350.
    • (2006) Mol Ther , vol.14 , pp. 343-350
    • Kim, W.J.1    Christensen, L.V.2    Jo, S.3    Yockman, J.W.4    Jeong, J.H.5    Kim, Y.H.6
  • 63
    • 15944404674 scopus 로고    scopus 로고
    • Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation
    • Kudo Y, Kitajima S, Ogawa I, Kitagawa M, Miyauchi M, Takata T (2005a). Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation. Mol Cancer Ther 4:471-476.
    • (2005) Mol Cancer Ther , vol.4 , pp. 471-476
    • Kudo, Y.1    Kitajima, S.2    Ogawa, I.3    Kitagawa, M.4    Miyauchi, M.5    Takata, T.6
  • 64
    • 13444257433 scopus 로고    scopus 로고
    • Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma
    • Kudo Y, Kitajima S, Ogawa I, Miyauehi M, Takata T (2005b). Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma. Oral Oncol 41:105-116.
    • (2005) Oral Oncol , vol.41 , pp. 105-116
    • Kudo, Y.1    Kitajima, S.2    Ogawa, I.3    Miyauehi, M.4    Takata, T.5
  • 65
  • 66
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • Landthaler M, Yalein A, Tuschl T (2004). The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14:2162-2167.
    • (2004) Curr Biol , vol.14 , pp. 2162-2167
    • Landthaler, M.1    Yalein, A.2    Tuschl, T.3
  • 67
    • 0034465474 scopus 로고    scopus 로고
    • Autosomal dominant growth hormone (GH) deficiency type II: The Del32-71-GH deletion mutant suppresses secretion of wild-type GH
    • Lee MS, Wajnarajch MP, Kim SS, Plotnick LP, Wang J, Gertner JM, et al. (2000). Autosomal dominant growth hormone (GH) deficiency type II: the Del32-71-GH deletion mutant suppresses secretion of wild-type GH. Endocrinology 141:883-890.
    • (2000) Endocrinology , vol.141 , pp. 883-890
    • Lee, M.S.1    Wajnarajch, M.P.2    Kim, S.S.3    Plotnick, L.P.4    Wang, J.5    Gertner, J.M.6
  • 68
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y, Kim M, Han J, Yeom KH, Lee S, Back SH, et al. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23:4051-4060.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Back, S.H.6
  • 69
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H (2002), Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 32:107-108.
    • (2002) Nat Genet , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 72
    • 25144498128 scopus 로고    scopus 로고
    • In vivo application of RNA interference: From functional genomics to therapeutics
    • Lu PY, Xie F, Woodle MC (2005). In vivo application of RNA interference: from functional genomics to therapeutics. Adv Genet 54:117-142.
    • (2005) Adv Genet , vol.54 , pp. 117-142
    • Lu, P.Y.1    Xie, F.2    Woodle, M.C.3
  • 74
    • 34249804141 scopus 로고    scopus 로고
    • Protein i: Interference at protein level by inirabodies
    • Manikandan J, Pushparaj PN, Melendez AJ (2007). Protein i: interference at protein level by inirabodies. Front Biosci 12:1344-1352.
    • (2007) Front Biosci , vol.12 , pp. 1344-1352
    • Manikandan, J.1    Pushparaj, P.N.2    Melendez, A.J.3
  • 75
    • 36849026128 scopus 로고    scopus 로고
    • Applications of RNA interference in mammalian systems
    • Martin SE, Caplen NJ (2007). Applications of RNA interference in mammalian systems. Annu Rev Genomics Hum Genet 8:81-108.
    • (2007) Annu Rev Genomics Hum Genet , vol.8 , pp. 81-108
    • Martin, S.E.1    Caplen, N.J.2
  • 76
    • 0037032933 scopus 로고    scopus 로고
    • Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
    • Martinez MA, Gutierrez A, Armand-Ugon M, Blanco J, Parera M, Gomez J, et al. (2002). Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16:2385-2390.
    • (2002) AIDS , vol.16 , pp. 2385-2390
    • Martinez, M.A.1    Gutierrez, A.2    Armand-Ugon, M.3    Blanco, J.4    Parera, M.5    Gomez, J.6
  • 77
    • 27744590896 scopus 로고    scopus 로고
    • Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
    • Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD (2005). Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123:607-620.
    • (2005) Cell , vol.123 , pp. 607-620
    • Matranga, C.1    Tomari, Y.2    Shin, C.3    Bartel, D.P.4    Zamore, P.D.5
  • 79
    • 0345818258 scopus 로고    scopus 로고
    • MicroRNAs and cancer
    • McManus MT (2003). MicroRNAs and cancer. Semin Cancer Biol 13:253-258.
    • (2003) Semin Cancer Biol , vol.13 , pp. 253-258
    • McManus, M.T.1
  • 80
    • 35948948204 scopus 로고    scopus 로고
    • Inhibition of Fe epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes
    • Melendez AJ, Hamett MM, Pushparaj PN, Wong WS, Tay HR, McSharry CP, et al. (2007). Inhibition of Fe epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes. Nat Med 13:1375-1381.
    • (2007) Nat Med , vol.13 , pp. 1375-1381
    • Melendez, A.J.1    Hamett, M.M.2    Pushparaj, P.N.3    Wong, W.S.4    Tay, H.R.5    McSharry, C.P.6
  • 81
    • 3242733298 scopus 로고    scopus 로고
    • Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
    • Minakuchi Y, Takcshita F, Kosaka N, Sasaki H, Yamamolo Y, Kouno M, et al. (2004). Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 32:e109.
    • (2004) Nucleic Acids Res , vol.32
    • Minakuchi, Y.1    Takcshita, F.2    Kosaka, N.3    Sasaki, H.4    Yamamolo, Y.5    Kouno, M.6
  • 82
    • 0018801485 scopus 로고
    • Structural requirements of double-stranded RNA for the activation of 2′,5′-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells
    • Minks MA, West DK, Benvin S, Baglioni C (1979). Structural requirements of double-stranded RNA for the activation of 2′,5′-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells. J Biol Chem 254:10180-10183.
    • (1979) J Biol Chem , vol.254 , pp. 10180-10183
    • Minks, M.A.1    West, D.K.2    Benvin, S.3    Baglioni, C.4
  • 83
    • 0038301176 scopus 로고    scopus 로고
    • Long-term experience with GH replacement therapy: Efficacy and safety
    • Monson JP (2003). Long-term experience with GH replacement therapy: efficacy and safety. Eur J Endocrinol 148(Suppl 2):9-14.
    • (2003) Eur J Endocrinol , vol.148 , Issue.SUPPL. 2 , pp. 9-14
    • Monson, J.P.1
  • 85
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • Nykanen A, Haley B, Zamore PD (2001), ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107:309-321.
    • (2001) Cell , vol.107 , pp. 309-321
    • Nykanen, A.1    Haley, B.2    Zamore, P.D.3
  • 87
    • 41149130219 scopus 로고    scopus 로고
    • Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
    • O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nieoll J, et al. (2008). Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 205:585-594.
    • (2008) J Exp Med , vol.205 , pp. 585-594
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Boldin, M.P.4    Taganov, K.D.5    Nieoll, J.6
  • 89
    • 64149125745 scopus 로고    scopus 로고
    • Pitsch S, Weiss PA (2001). Chemical synthesis of RNA-sequences with 2′-0-[(triisopropylsilyl)oxy]methyT-protected ribonucleoside phosphoramidites (=TOM-phosphoramidites) (Unit 3.9). In: Current protocols of nucleic acid chemistry. Beaucagc S, editor. New York, NY: John Wiley & Sons, Inc.
    • Pitsch S, Weiss PA (2001). Chemical synthesis of RNA-sequences with 2′-0-[(triisopropylsilyl)oxy]methyT-protected ribonucleoside phosphoramidites (=TOM-phosphoramidites) (Unit 3.9). In: Current protocols of nucleic acid chemistry. Beaucagc S, editor. New York, NY: John Wiley & Sons, Inc.
  • 90
    • 0032884788 scopus 로고    scopus 로고
    • Fast and reliable automated synthesis of RNA and partially 2′-0-protccted precursors ("caged RNA") based on two novel, orthogonal 2′-0-protecting groups
    • Pitsch S, Weiss PA, Wu X, Ackermann D, Honegger T (1999). Fast and reliable automated synthesis of RNA and partially 2′-0-protccted precursors ("caged RNA") based on two novel, orthogonal 2′-0-protecting groups. Helv Chim Acta 82:1753-1761.
    • (1999) Helv Chim Acta , vol.82 , pp. 1753-1761
    • Pitsch, S.1    Weiss, P.A.2    Wu, X.3    Ackermann, D.4    Honegger, T.5
  • 91
    • 0035692119 scopus 로고    scopus 로고
    • Reliable chemical synthesis of oligoribonucleotides (RNA) with 2′-0-[(triisopropylsilyl) oxy]methyl (2′-0-TOM) protected phosphoramiditcs
    • Pitsch S, Weiss PA, Jenny L, Stutz A, Wu X (2001). Reliable chemical synthesis of oligoribonucleotides (RNA) with 2′-0-[(triisopropylsilyl) oxy]methyl (2′-0-TOM) protected phosphoramiditcs. Helv Chim Acta 84:3773-3795.
    • (2001) Helv Chim Acta , vol.84 , pp. 3773-3795
    • Pitsch, S.1    Weiss, P.A.2    Jenny, L.3    Stutz, A.4    Wu, X.5
  • 93
    • 35148819250 scopus 로고    scopus 로고
    • mieroRNAs and the regulation of glucose and lipid metabolism
    • Poy MN, Spranger M, Stoffel M (2007). mieroRNAs and the regulation of glucose and lipid metabolism. Diabetes Obes Metab 9(Suppl 2):67-73.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.SUPPL. 2 , pp. 67-73
    • Poy, M.N.1    Spranger, M.2    Stoffel, M.3
  • 94
  • 96
    • 49949152287 scopus 로고    scopus 로고
    • Refining siRNA in vivo transfection: Silencing SPHK1 reveals its key role in C5a-induced inflammation in vivo
    • Pushparaj PN, H'ng SC, Melendez AJ (2008b). Refining siRNA in vivo transfection: Silencing SPHK1 reveals its key role in C5a-induced inflammation in vivo. Int J Biochem Cell Biol 40:1817-1825.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 1817-1825
    • Pushparaj, P.N.1    H'ng, S.C.2    Melendez, A.J.3
  • 97
    • 27744506761 scopus 로고    scopus 로고
    • Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
    • Rand TA, Petersen S, Du F, Wang X (2005). Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123:621-629.
    • (2005) Cell , vol.123 , pp. 621-629
    • Rand, T.A.1    Petersen, S.2    Du, F.3    Wang, X.4
  • 98
    • 0036904741 scopus 로고    scopus 로고
    • Intravascular adenoviral agents in cancer patients: Lessons from clinical trials
    • Reid T, Warren R, Kirn D (2002). Intravascular adenoviral agents in cancer patients: lessons from clinical trials. Cancer Gene Ther 9:979-986.
    • (2002) Cancer Gene Ther , vol.9 , pp. 979-986
    • Reid, T.1    Warren, R.2    Kirn, D.3
  • 100
    • 2542427517 scopus 로고    scopus 로고
    • GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allcle-specific small interfering RNA (siRNA)
    • Ryther RC, Flynt AS, Harris BD, Phillips JA 3rd, Patton JG (2004). GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allcle-specific small interfering RNA (siRNA). Endocrinology 145:2988-2996.
    • (2004) Endocrinology , vol.145 , pp. 2988-2996
    • Ryther, R.C.1    Flynt, A.S.2    Harris, B.D.3    Phillips 3rd, J.A.4    Patton, J.G.5
  • 101
    • 0036561252 scopus 로고    scopus 로고
    • Expression profiling of mammary carcinoma cell lines: Correlation of in vitro invasiveness with expression of CD24
    • Schindelmann S, Windisch J, Grundmann R, Kreienberg R, Zeillinger R, Deissler H (2002). Expression profiling of mammary carcinoma cell lines: correlation of in vitro invasiveness with expression of CD24. Tumour Biol 23:139-145.
    • (2002) Tumour Biol , vol.23 , pp. 139-145
    • Schindelmann, S.1    Windisch, J.2    Grundmann, R.3    Kreienberg, R.4    Zeillinger, R.5    Deissler, H.6
  • 102
    • 33645072440 scopus 로고    scopus 로고
    • Gene sequencing. The race for the $1000 genome
    • Service RF
    • Service RF (2006). Gene sequencing. The race for the $1000 genome. Science 311:1544-1546.
    • (2006) Science , vol.311 , pp. 1544-1546
  • 103
    • 33947207871 scopus 로고    scopus 로고
    • Reduction of CD44 expression results in growth inhibition of human nasopharyngeal carcinoma cell CNE-2L2 in vitro]
    • article in Chinese
    • Shi Y, Tian Y, Zhou YQ, Ju JY, Liu Y, Zhu LP (2007a). [Reduction of CD44 expression results in growth inhibition of human nasopharyngeal carcinoma cell CNE-2L2 in vitro]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 29:67-72 [article in Chinese].
    • (2007) Zhongguo Yi Xue Ke Xue Yuan Xue Bao , vol.29 , pp. 67-72
    • Shi, Y.1    Tian, Y.2    Zhou, Y.Q.3    Ju, J.Y.4    Liu, Y.5    Zhu, L.P.6
  • 104
    • 34548527034 scopus 로고    scopus 로고
    • Inhibition of malignant activities of nasopharyngeal carcinoma cells with high expression of CD44 by siRNA
    • Shi Y, Tian Y, Zhou YQ, Ju JY, Qu L, Chen SL, et al. (2007b). Inhibition of malignant activities of nasopharyngeal carcinoma cells with high expression of CD44 by siRNA. Oncol Rep 18:397-403.
    • (2007) Oncol Rep , vol.18 , pp. 397-403
    • Shi, Y.1    Tian, Y.2    Zhou, Y.Q.3    Ju, J.Y.4    Qu, L.5    Chen, S.L.6
  • 106
    • 23844474160 scopus 로고    scopus 로고
    • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
    • Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoom DM, et al. (2005). Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 23:709-717.
    • (2005) Nat Biotechnol , vol.23 , pp. 709-717
    • Song, E.1    Zhu, P.2    Lee, S.K.3    Chowdhury, D.4    Kussman, S.5    Dykxhoom, D.M.6
  • 107
    • 33744938416 scopus 로고    scopus 로고
    • Application of lentivirus-mediated RNAi in studying gene function in mammalian tooth development
    • Song Y, Zhang Z, Yu X, Yan M, Zhang X, Gu S, et al. (2006). Application of lentivirus-mediated RNAi in studying gene function in mammalian tooth development. Dev Dyn 235:1334-1344.
    • (2006) Dev Dyn , vol.235 , pp. 1334-1344
    • Song, Y.1    Zhang, Z.2    Yu, X.3    Yan, M.4    Zhang, X.5    Gu, S.6
  • 108
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • Sorensen DR, Leirdal M, Sioud M (2003). Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J Mol Biol 327:761-766.
    • (2003) J Mol Biol , vol.327 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 109
    • 0037605839 scopus 로고    scopus 로고
    • Physiological and technological aspects of RNAi]
    • article in Japanese
    • Tabara H, Yasuda J (2003). [Physiological and technological aspects of RNAi]. Tanpakushitsu Kakusan Koso 48(4 Suppl):469-479 [article in Japanese].
    • (2003) Tanpakushitsu Kakusan Koso , vol.48 , Issue.4 SUPPL. , pp. 469-479
    • Tabara, H.1    Yasuda, J.2
  • 110
    • 0037188904 scopus 로고    scopus 로고
    • The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans
    • Tabara H, Yigit E, Siomi H, Mello CC (2002). The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell 109:861-871.
    • (2002) Cell , vol.109 , pp. 861-871
    • Tabara, H.1    Yigit, E.2    Siomi, H.3    Mello, C.C.4
  • 111
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependenl induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006). NF-kappaB-dependenl induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sei USA 103:12481-12486.
    • (2006) Proc Natl Acad Sei USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 112
    • 33847311819 scopus 로고    scopus 로고
    • MieroRNAs and immunity: Tiny players in abig field
    • Taganov KD, Boldin MP, Baltimore D (2007). MieroRNAs and immunity: tiny players in abig field. Immunity 26:133-137.
    • (2007) Immunity , vol.26 , pp. 133-137
    • Taganov, K.D.1    Boldin, M.P.2    Baltimore, D.3
  • 113
    • 33745625836 scopus 로고    scopus 로고
    • Therapeutic potential of RNA interference against cancer
    • Takeshita F, Ochiya T (2006). Therapeutic potential of RNA interference against cancer. Cancer Sci 97:689-696.
    • (2006) Cancer Sci , vol.97 , pp. 689-696
    • Takeshita, F.1    Ochiya, T.2
  • 114
    • 24744464786 scopus 로고    scopus 로고
    • Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
    • Takeshita F, Minakuchi Y, Nagahara S, Honma K, Sasaki H, Hirai K, et al. (2005). Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci USA 102:12177-12182.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12177-12182
    • Takeshita, F.1    Minakuchi, Y.2    Nagahara, S.3    Honma, K.4    Sasaki, H.5    Hirai, K.6
  • 116
    • 0038784432 scopus 로고    scopus 로고
    • Inducible systemic RNA silencing in Caenorhabditis elegans
    • Timmons L, Tabara H, Mello CC, Fire AZ (2003). Inducible systemic RNA silencing in Caenorhabditis elegans. Mol Biol Cell 14:2972-2983.
    • (2003) Mol Biol Cell , vol.14 , pp. 2972-2983
    • Timmons, L.1    Tabara, H.2    Mello, C.C.3    Fire, A.Z.4
  • 117
    • 33845317603 scopus 로고    scopus 로고
    • A signature pattern of stress-responsive mieroRNAs that can evoke cardiac hypertrophy and heart failure
    • van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, et al. (2006). A signature pattern of stress-responsive mieroRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci USA 103:18255-18260.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 18255-18260
    • van Rooij, E.1    Sutherland, L.B.2    Liu, N.3    Williams, A.H.4    McAnally, J.5    Gerard, R.D.6
  • 118
    • 0036168787 scopus 로고    scopus 로고
    • HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans
    • Victor M, Bei Y, Gay F, Calvo D, Mello C, Shi Y (2002). HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans. EMBO Rep 3:50-55.
    • (2002) EMBO Rep , vol.3 , pp. 50-55
    • Victor, M.1    Bei, Y.2    Gay, F.3    Calvo, D.4    Mello, C.5    Shi, Y.6
  • 119
    • 18644380561 scopus 로고    scopus 로고
    • A critical role for sphingoslne kinase in anaphylatoxin-induced neutropenia, peritonitis, and cytokine production in vivo
    • Vlasenko LP, Melendez AJ (2005). A critical role for sphingoslne kinase in anaphylatoxin-induced neutropenia, peritonitis, and cytokine production in vivo. J Immunol 174:6456-6461.
    • (2005) J Immunol , vol.174 , pp. 6456-6461
    • Vlasenko, L.P.1    Melendez, A.J.2
  • 120
    • 30644473108 scopus 로고    scopus 로고
    • Antibody-directed cell-type-specific delivery of siRNA
    • Vomlocher HP (2006). Antibody-directed cell-type-specific delivery of siRNA. Trends Mol Med 12:1-3.
    • (2006) Trends Mol Med , vol.12 , pp. 1-3
    • Vomlocher, H.P.1
  • 121
    • 47049099443 scopus 로고    scopus 로고
    • Therapeutic gene silencing delivered by a chemically modified siRNA against mutant SOD1 slows ALS progression
    • Wang H, Ghosh A, Baigude H, Yang CS, Qiu L, Xia X, et al. (2008). Therapeutic gene silencing delivered by a chemically modified siRNA against mutant SOD1 slows ALS progression. J Biol Chetn 283:15845-15852.
    • (2008) J Biol Chetn , vol.283 , pp. 15845-15852
    • Wang, H.1    Ghosh, A.2    Baigude, H.3    Yang, C.S.4    Qiu, L.5    Xia, X.6
  • 122
    • 11844273868 scopus 로고    scopus 로고
    • RNA Interference in Caenorhabditis elegans
    • Wang J, Barr MM (2005). RNA Interference in Caenorhabditis elegans. Methods Enzymol 392:36-55.
    • (2005) Methods Enzymol , vol.392 , pp. 36-55
    • Wang, J.1    Barr, M.M.2
  • 123
    • 35748948383 scopus 로고    scopus 로고
    • Liver target delivery of small interfering RNA to the HCV gene by laetosylated eationie liposome
    • Watanabe T, Umehara T, Yasui F, Nakagawa SI, Yano J, Ohgi T, et al. (2007). Liver target delivery of small interfering RNA to the HCV gene by laetosylated eationie liposome. J Hepatol 47:744-750.
    • (2007) J Hepatol , vol.47 , pp. 744-750
    • Watanabe, T.1    Umehara, T.2    Yasui, F.3    Nakagawa, S.I.4    Yano, J.5    Ohgi, T.6
  • 124
    • 34250378330 scopus 로고    scopus 로고
    • MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts
    • Xiao J, Luo X, Lin H, Zhang Y, Lu Y, Wang N, et al. (2007). MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts. J Biol Chem 282:12363-12367.
    • (2007) J Biol Chem , vol.282 , pp. 12363-12367
    • Xiao, J.1    Luo, X.2    Lin, H.3    Zhang, Y.4    Lu, Y.5    Wang, N.6
  • 125
    • 32444445649 scopus 로고    scopus 로고
    • Harnessing in vivo siRNA delivery for drug discovery and therapeutic development
    • Xie FY, Woodle MC, Lu PY (2006). Harnessing in vivo siRNA delivery for drug discovery and therapeutic development. Drug Discov Today 11:67-73.
    • (2006) Drug Discov Today , vol.11 , pp. 67-73
    • Xie, F.Y.1    Woodle, M.C.2    Lu, P.Y.3
  • 126
    • 0035913721 scopus 로고    scopus 로고
    • Expression profile of active genes in human periodontal ligament and isolation of PLAP-1, a novel SLRP family gene
    • Yamada S, Murakami S, Matoba R, Ozawa Y, Yokokoji T, Nakahira Y, et al. (2001). Expression profile of active genes in human periodontal ligament and isolation of PLAP-1, a novel SLRP family gene. Gene 275:279-286.
    • (2001) Gene , vol.275 , pp. 279-286
    • Yamada, S.1    Murakami, S.2    Matoba, R.3    Ozawa, Y.4    Yokokoji, T.5    Nakahira, Y.6
  • 127
    • 34548181316 scopus 로고    scopus 로고
    • PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization
    • Yamada S, Tomoeda M, Ozawa Y, Yoneda S, Terashima Y, Ikezawa K, et al. (2007). PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization. J Biol Chem 282:23070-23080.
    • (2007) J Biol Chem , vol.282 , pp. 23070-23080
    • Yamada, S.1    Tomoeda, M.2    Ozawa, Y.3    Yoneda, S.4    Terashima, Y.5    Ikezawa, K.6
  • 128
    • 18844430787 scopus 로고    scopus 로고
    • Silencing of the p53R2 gene by RNA Interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells
    • Yanamoto S, Iwamoto T, Kawasaki G, Yoshitomi I, Baba N, Mizuno A (2005). Silencing of the p53R2 gene by RNA Interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells. Cancer Lett 223:67-76.
    • (2005) Cancer Lett , vol.223 , pp. 67-76
    • Yanamoto, S.1    Iwamoto, T.2    Kawasaki, G.3    Yoshitomi, I.4    Baba, N.5    Mizuno, A.6
  • 129
    • 34147095310 scopus 로고    scopus 로고
    • The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
    • Yang B, Lin H, Xiao J, Lu Y, Luo X, Li B, et al. (2007). The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med 13:486-491.
    • (2007) Nat Med , vol.13 , pp. 486-491
    • Yang, B.1    Lin, H.2    Xiao, J.3    Lu, Y.4    Luo, X.5    Li, B.6
  • 130
    • 33748300738 scopus 로고    scopus 로고
    • Regulation of E-eadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cells
    • Ye P, Nadkarni MA, Hunter N (2006). Regulation of E-eadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cells. Biochem Biophys Res Commun 349:229-235.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 229-235
    • Ye, P.1    Nadkarni, M.A.2    Hunter, N.3
  • 131
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR (2003). Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17:3011 -3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 132
    • 34548818764 scopus 로고    scopus 로고
    • Cationic lipids and polymers mediated vectors for delivery of siRNA
    • Zhang S, Zhao B, Jiang H, Wang B, Ma B (2007). Cationic lipids and polymers mediated vectors for delivery of siRNA. J Control Release 123:1-10.
    • (2007) J Control Release , vol.123 , pp. 1-10
    • Zhang, S.1    Zhao, B.2    Jiang, H.3    Wang, B.4    Ma, B.5
  • 133
    • 0035164784 scopus 로고    scopus 로고
    • Double-stranded RNA injection produces non-specific defects in zebrafish
    • Zhao Z, Cao Y, Li M, Meng A (2001). Double-stranded RNA injection produces non-specific defects in zebrafish. Dev Biol 229:215-223.
    • (2001) Dev Biol , vol.229 , pp. 215-223
    • Zhao, Z.1    Cao, Y.2    Li, M.3    Meng, A.4
  • 134
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao Y, Samal E, Srivastava D (2005). Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436:214-220.
    • (2005) Nature , vol.436 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 135
    • 34147153781 scopus 로고    scopus 로고
    • Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1 -2
    • Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, et al. (2007). Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1 -2. Cell 129:303-317.
    • (2007) Cell , vol.129 , pp. 303-317
    • Zhao, Y.1    Ransom, J.F.2    Li, A.3    Vedantham, V.4    von Drehle, M.5    Muth, A.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.