-
1
-
-
34248682403
-
RNAi therapcutics: Principles, prospects and challenges
-
Aagaard L, Rossi JJ (2007). RNAi therapcutics: principles, prospects and challenges. Adv Drug Deliv Rev 59:75-86.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 75-86
-
-
Aagaard, L.1
Rossi, J.J.2
-
2
-
-
0037440005
-
Tolerance for mutations and chemical modifications in a siRNA
-
Amarzguioui M, Holen T, Babaie E, Prydz H (2003), Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res 31:589-595.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 589-595
-
-
Amarzguioui, M.1
Holen, T.2
Babaie, E.3
Prydz, H.4
-
3
-
-
64149108725
-
The functions of animal microRNAs, Nature 431:350-Azzouz M (2006). Gene therapy for ALS: Progress and prospects
-
Ambros V (2004). The functions of animal microRNAs, Nature 431:350-Azzouz M (2006). Gene therapy for ALS: progress and prospects. Biochim Biophys Acta 1762:1122-1127.
-
(2004)
Biochim Biophys Acta
, vol.1762
, pp. 1122-1127
-
-
Ambros, V.1
-
4
-
-
0018352913
-
Interferon-induced enzymatic activities and their role in the antriviral state
-
Baglioni C (1979). Interferon-induced enzymatic activities and their role in the antriviral state. Cell 17:255-264.
-
(1979)
Cell
, vol.17
, pp. 255-264
-
-
Baglioni, C.1
-
5
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
0031061733
-
The periodontal ligament: A unique, multifunctional connective tissue
-
Beertsen W, McCulloch CA, Sodek J (1997). The periodontal ligament: a unique, multifunctional connective tissue. Periodontal 2000 13:20-40.
-
(1997)
Periodontal 2000
, vol.13
, pp. 20-40
-
-
Beertsen, W.1
McCulloch, C.A.2
Sodek, J.3
-
8
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon OJ (2001a). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, O.J.4
-
10
-
-
0242266620
-
Dicer is essential for mouse development
-
Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcom H, Li MZ, et al. (2003). Dicer is essential for mouse development. Nat Genet 35:215-217.
-
(2003)
Nat Genet
, vol.35
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
Murchison, E.P.4
Alcom, H.5
Li, M.Z.6
-
11
-
-
1642499415
-
Exportin 5 is a RanGTP-+ dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
-
Bohnsack MT, Czaplinski K, Gorlich D (2004). Exportin 5 is a RanGTP-+ dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10:185-191.
-
(2004)
RNA
, vol.10
, pp. 185-191
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Gorlich, D.3
-
12
-
-
33747876113
-
-
Calin GA, Croce CM (2006a). MicroRNA-cancer connection: the beginning of a new tale. Cancer Res 66:7390-7394. Calin GA, Croee CM (2006b). MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866.
-
Calin GA, Croce CM (2006a). MicroRNA-cancer connection: the beginning of a new tale. Cancer Res 66:7390-7394. Calin GA, Croee CM (2006b). MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866.
-
-
-
-
13
-
-
18744396337
-
Frequent deletions and down-regulation of miero-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitm CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. (2002). Frequent deletions and down-regulation of miero-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99:15524-15529.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitm, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
-
14
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, et al. (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101:2999-3004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
-
15
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen NJ, Parrish S, Imani F, Fire A, Morgan RA (2001). Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci USA 98:9742-9747.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
16
-
-
33747754760
-
Lessons from nature: MicroRNA-based shRNA libraries
-
Chang K, Elledge SJ, Hannon GJ (2006). Lessons from nature: microRNA-based shRNA libraries. Nat Methods 3:707-714.
-
(2006)
Nat Methods
, vol.3
, pp. 707-714
-
-
Chang, K.1
Elledge, S.J.2
Hannon, G.J.3
-
17
-
-
34548164577
-
RNA interference: Hitting the on switch
-
Cheek E (2007). RNA interference: hitting the on switch. Nature 448:855-858.
-
(2007)
Nature
, vol.448
, pp. 855-858
-
-
Cheek, E.1
-
18
-
-
33846309616
-
DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis
-
Chen YJ, Chang JT, Lee L, Wang HM, Liao CT, Chiu CC, et al. (2007). DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. Oncogene 26:467-476.
-
(2007)
Oncogene
, vol.26
, pp. 467-476
-
-
Chen, Y.J.1
Chang, J.T.2
Lee, L.3
Wang, H.M.4
Liao, C.T.5
Chiu, C.C.6
-
19
-
-
0041331496
-
siRNA function in RNAi: A chemical modification analysis
-
Chiu YL, Rana TM (2003). siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-1048.
-
(2003)
RNA
, vol.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
Rana, T.M.2
-
20
-
-
9144224451
-
Processing of primary microRNAs by the microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ (2004). Processing of primary microRNAs by the microprocessor complex. Nature 432:231-235.
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
21
-
-
36749033738
-
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits
-
DiFiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, et al. (2007). Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci USA 104:17204-17209.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 17204-17209
-
-
DiFiglia, M.1
Sena-Esteves, M.2
Chase, K.3
Sapp, E.4
Pfister, E.5
Sass, M.6
-
22
-
-
14844354250
-
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
-
Eis PS, Tarn W, Sun L, Chadbum A, Li Z, Gomez MF, et al. (2005). Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 102:3627-3632.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3627-3632
-
-
Eis, P.S.1
Tarn, W.2
Sun, L.3
Chadbum, A.4
Li, Z.5
Gomez, M.F.6
-
23
-
-
0036351317
-
Analysis of gene fonction in somatic mammalian cells using small interfering RNAs
-
Elbashir SM, Harborth J, Weber K, Tuschl T (2002). Analysis of gene fonction in somatic mammalian cells using small interfering RNAs. Methods 26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
24
-
-
34248634004
-
Therapeutic potential for microRNAs
-
Esau CC, Monia BP (2007). Therapeutic potential for microRNAs. Adv Drug Deliv Rev 59:101-114.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 101-114
-
-
Esau, C.C.1
Monia, B.P.2
-
25
-
-
10344243662
-
MicroRNA-143 regulates adipocyte differentiation
-
Esau C, Rang X, Peralta E, Hanson E, Marcusson EG, Ravichandran LV, et al. (2004). MicroRNA-143 regulates adipocyte differentiation. J Biol Chem 279:52361-52365.
-
(2004)
J Biol Chem
, vol.279
, pp. 52361-52365
-
-
Esau, C.1
Rang, X.2
Peralta, E.3
Hanson, E.4
Marcusson, E.G.5
Ravichandran, L.V.6
-
26
-
-
42349087572
-
Long-lasting in vivo gene silencing by eleclrotransfer of shRNA expressing plasmid
-
Escoffre JM, Debin A, Reynes JP, Drocourt D, Tiraby G, Hellaudais L, et al. (2008). Long-lasting in vivo gene silencing by eleclrotransfer of shRNA expressing plasmid. Technol Cancer Res Treat 7:109-116.
-
(2008)
Technol Cancer Res Treat
, vol.7
, pp. 109-116
-
-
Escoffre, J.M.1
Debin, A.2
Reynes, J.P.3
Drocourt, D.4
Tiraby, G.5
Hellaudais, L.6
-
27
-
-
0037443035
-
Pre-mRNA splicing and human disease
-
Faustino NA, Cooper TA (2003). Pre-mRNA splicing and human disease. Genes Dev 17:419-437.
-
(2003)
Genes Dev
, vol.17
, pp. 419-437
-
-
Faustino, N.A.1
Cooper, T.A.2
-
28
-
-
33750031102
-
Vector-based RNAi approaches for stable, inducible and genome-wide screens
-
Fewell GD, Schmitt K (2006). Vector-based RNAi approaches for stable, inducible and genome-wide screens. Drug Discov Today 11:975-982.
-
(2006)
Drug Discov Today
, vol.11
, pp. 975-982
-
-
Fewell, G.D.1
Schmitt, K.2
-
29
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
30
-
-
39049177605
-
Genetics. Small RNAs reveal an activating side
-
Garber K (2006). Genetics. Small RNAs reveal an activating side. Science 314:741-742.
-
(2006)
Science
, vol.314
, pp. 741-742
-
-
Garber, K.1
-
32
-
-
44649114578
-
Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis
-
Golzio M, Teissie J (2008). Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis. Methods Mol Biol 423:279-287.
-
(2008)
Methods Mol Biol
, vol.423
, pp. 279-287
-
-
Golzio, M.1
Teissie, J.2
-
33
-
-
13544265637
-
Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery
-
Golzio M, Mazzolini L, Moller P, Rols MP, Teissie J (2005). Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery. Gene Ther 12:246-251.
-
(2005)
Gene Ther
, vol.12
, pp. 246-251
-
-
Golzio, M.1
Mazzolini, L.2
Moller, P.3
Rols, M.P.4
Teissie, J.5
-
34
-
-
9144225636
-
The microprocessor complex mediates the genesis of microRNAs
-
Gregory RI, Yan KP, Amuthan G, Chcndrimada T, Doratotaj B, Cooch N, et al. (2004). The microprocessor complex mediates the genesis of microRNAs. Nature 432:235-240.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chcndrimada, T.4
Doratotaj, B.5
Cooch, N.6
-
35
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posltranscriptional gene silencing
-
Gregory RI, Chcndrimada TP, Cooch N, Shiekhattar R (2005). Human RISC couples microRNA biogenesis and posltranscriptional gene silencing. Cell 123:631-640.
-
(2005)
Cell
, vol.123
, pp. 631-640
-
-
Gregory, R.I.1
Chcndrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
36
-
-
26944450901
-
RNAi mechanisms in Caenorhabditis elegans
-
Grishok A (2005). RNAi mechanisms in Caenorhabditis elegans. FEBS Lett 579:5932-5939.
-
(2005)
FEBS Lett
, vol.579
, pp. 5932-5939
-
-
Grishok, A.1
-
37
-
-
0034737747
-
Genetic requirements for inheritance of RNAi in C. elegans
-
Grishok A, Tabara H, Mello CC (2000). Genetic requirements for inheritance of RNAi in C. elegans. Science 287:2494-2497.
-
(2000)
Science
, vol.287
, pp. 2494-2497
-
-
Grishok, A.1
Tabara, H.2
Mello, C.C.3
-
38
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, et al. (2001). Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34.
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
Ha, I.6
-
39
-
-
0034673638
-
An RNA-directed nuclease mediates post-transeriptional gene silencing in Drosophila cells
-
Hammond SM, Bernstein E, Beach D, Hannon GJ (2000). An RNA-directed nuclease mediates post-transeriptional gene silencing in Drosophila cells. Nature 404:293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
40
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN (2004). The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18:3016-3027.
-
(2004)
Genes Dev
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
41
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
Hannon GJ, Rossi JJ (2004). Unlocking the potential of the human genome with RNA interference. Nature 431:371-378.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
42
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
Harborth J, Elbashir SM, Vandenburgh K, Manninga H, Scaringc SA, Weber K, et al. (2003). Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing, Antisense Nucleic Acid Drug Dev 13:83-105.
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
Manninga, H.4
Scaringc, S.A.5
Weber, K.6
-
43
-
-
22144477115
-
MicroRNAs in vertebrale development
-
Harfe BD (2005). MicroRNAs in vertebrale development. Curr Opin Genet Dev 15:410-415.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 410-415
-
-
Harfe, B.D.1
-
45
-
-
33748209616
-
Efficient prediction of siRNAs with siRNArulcs 1.0: An open-source JAVA approach to siRNA algorithms
-
Holen T (2006). Efficient prediction of siRNAs with siRNArulcs 1.0: an open-source JAVA approach to siRNA algorithms. RNA 12:1620-1625.
-
(2006)
RNA
, vol.12
, pp. 1620-1625
-
-
Holen, T.1
-
46
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
-
Holen T, Amarzguioui M, Wiiger MT, Babaie E, Prydz H (2002). Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res 30:1757-1766.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
47
-
-
25844450312
-
High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA interference in the mouse
-
Hong J, Qian Z, Shen S, Min T, Tan C, Xu J, et al. (2005), High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA interference in the mouse. Biochem J 390(Pt 3):675-679.
-
(2005)
Biochem J
, vol.390
, Issue.PART 3
, pp. 675-679
-
-
Hong, J.1
Qian, Z.2
Shen, S.3
Min, T.4
Tan, C.5
Xu, J.6
-
48
-
-
34247581261
-
Application of atelocollagen-mediated si RNA delivery for RNAi therapies]
-
article in Japanese
-
Honma K, Takeshita F, Ochiya T (2007). [Application of atelocollagen-mediated si RNA delivery for RNAi therapies]. Yalmgaku Zasshi 127:807-812 [article in Japanese].
-
(2007)
Yalmgaku Zasshi
, vol.127
, pp. 807-812
-
-
Honma, K.1
Takeshita, F.2
Ochiya, T.3
-
49
-
-
2342564353
-
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens
-
Hsieh AC, Bo R, Manola J, Vazquez F, Bare O, Khvorova A, et al. (2004). A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens. Nucleic Acids Res 32:893-901.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 893-901
-
-
Hsieh, A.C.1
Bo, R.2
Manola, J.3
Vazquez, F.4
Bare, O.5
Khvorova, A.6
-
50
-
-
1942469322
-
Analysis of elathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference
-
Huang F, Khvorova A, Marshall W, Sorkin A (2004). Analysis of elathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem 279:16657-16661.
-
(2004)
J Biol Chem
, vol.279
, pp. 16657-16661
-
-
Huang, F.1
Khvorova, A.2
Marshall, W.3
Sorkin, A.4
-
51
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-? small temporal RNA
-
Hulvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-? small temporal RNA. Science 293:834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hulvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
52
-
-
19344378192
-
Sequence-specific inhibition of small RNA function
-
Hutvagner G, Simard MJ, Mello CC, Zamore PD (2004). Sequence-specific inhibition of small RNA function, PLoS Biol 2(4):E98.
-
(2004)
PLoS Biol
, vol.2
, Issue.4
-
-
Hutvagner, G.1
Simard, M.J.2
Mello, C.C.3
Zamore, P.D.4
-
53
-
-
33748337330
-
Silencing gene expression by targeting chromosomal DNA with antigene peptide nucleic acids arid duplex RNAs
-
Janowski BA, Hu J, Corey DR (2006). Silencing gene expression by targeting chromosomal DNA with antigene peptide nucleic acids arid duplex RNAs. Nat Protoc 1:436-443.
-
(2006)
Nat Protoc
, vol.1
, pp. 436-443
-
-
Janowski, B.A.1
Hu, J.2
Corey, D.R.3
-
54
-
-
33847081733
-
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
-
Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR (2007). Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat Chem Biol 3:166-173.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 166-173
-
-
Janowski, B.A.1
Younger, S.T.2
Hardy, D.B.3
Ram, R.4
Huffman, K.E.5
Corey, D.R.6
-
55
-
-
36248978183
-
Experimental siCD44-targeted therapy of human nasopharyngeal carcinoma mediated by adenovirus]
-
article in Chinese
-
Jod JY, Shi Y, Zhou YQ, Tian Y, Shen L, Liu Y, et al. (2007). [Experimental siCD44-targeted therapy of human nasopharyngeal carcinoma mediated by adenovirus]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 29:626-630 [article in Chinese].
-
(2007)
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
, vol.29
, pp. 626-630
-
-
Jod, J.Y.1
Shi, Y.2
Zhou, Y.Q.3
Tian, Y.4
Shen, L.5
Liu, Y.6
-
56
-
-
0024283243
-
The nematode Caenorhabditis elegans
-
Kenyon C (1988). The nematode Caenorhabditis elegans. Science 240:1448 1453.
-
(1988)
Science
, vol.240
, pp. 1448-1453
-
-
Kenyon, C.1
-
57
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH (2001). Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15:2654-2659.
-
(2001)
Genes Dev
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
58
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A, Reynolds A, Jayasena SD (2003). Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
59
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
Kim DH, Behlke MA, Rose SD, Chang MS, Choi S, Rossi JJ (2005). Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat Biotechnol 23:222-226.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
60
-
-
34249279852
-
Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I
-
Kim SI, Shin D, Choi TH, Lee JC, Cheon GJ, Kim KY, et al (2007). Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I. Mol Ther 15:1145-1152.
-
(2007)
Mol Ther
, vol.15
, pp. 1145-1152
-
-
Kim, S.I.1
Shin, D.2
Choi, T.H.3
Lee, J.C.4
Cheon, G.J.5
Kim, K.Y.6
-
61
-
-
18344373363
-
Small RNAs: Classification, biogenesis, and function
-
Kim VN (2005). Small RNAs: classification, biogenesis, and function. Mol Cells 19:1-15.
-
(2005)
Mol Cells
, vol.19
, pp. 1-15
-
-
Kim, V.N.1
-
62
-
-
33746863376
-
Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma
-
Kim WJ, Christensen LV, Jo S, Yockman JW, Jeong JH, Kim YH, et al. (2006). Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma. Mol Ther 14:343-350.
-
(2006)
Mol Ther
, vol.14
, pp. 343-350
-
-
Kim, W.J.1
Christensen, L.V.2
Jo, S.3
Yockman, J.W.4
Jeong, J.H.5
Kim, Y.H.6
-
63
-
-
15944404674
-
Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation
-
Kudo Y, Kitajima S, Ogawa I, Kitagawa M, Miyauchi M, Takata T (2005a). Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation. Mol Cancer Ther 4:471-476.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 471-476
-
-
Kudo, Y.1
Kitajima, S.2
Ogawa, I.3
Kitagawa, M.4
Miyauchi, M.5
Takata, T.6
-
64
-
-
13444257433
-
Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma
-
Kudo Y, Kitajima S, Ogawa I, Miyauehi M, Takata T (2005b). Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma. Oral Oncol 41:105-116.
-
(2005)
Oral Oncol
, vol.41
, pp. 105-116
-
-
Kudo, Y.1
Kitajima, S.2
Ogawa, I.3
Miyauehi, M.4
Takata, T.5
-
65
-
-
44849137343
-
The role of sphingosine kinase in a murine model of allergic asthma
-
Lai WQ, Goh HH, Bao Z, Wong WS, Melendez AJ, Leung BP (2008). The role of sphingosine kinase in a murine model of allergic asthma. J Immunol 180:4323-4329.
-
(2008)
J Immunol
, vol.180
, pp. 4323-4329
-
-
Lai, W.Q.1
Goh, H.H.2
Bao, Z.3
Wong, W.S.4
Melendez, A.J.5
Leung, B.P.6
-
66
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
-
Landthaler M, Yalein A, Tuschl T (2004). The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14:2162-2167.
-
(2004)
Curr Biol
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalein, A.2
Tuschl, T.3
-
67
-
-
0034465474
-
Autosomal dominant growth hormone (GH) deficiency type II: The Del32-71-GH deletion mutant suppresses secretion of wild-type GH
-
Lee MS, Wajnarajch MP, Kim SS, Plotnick LP, Wang J, Gertner JM, et al. (2000). Autosomal dominant growth hormone (GH) deficiency type II: the Del32-71-GH deletion mutant suppresses secretion of wild-type GH. Endocrinology 141:883-890.
-
(2000)
Endocrinology
, vol.141
, pp. 883-890
-
-
Lee, M.S.1
Wajnarajch, M.P.2
Kim, S.S.3
Plotnick, L.P.4
Wang, J.5
Gertner, J.M.6
-
68
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J, Yeom KH, Lee S, Back SH, et al. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23:4051-4060.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Back, S.H.6
-
69
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H (2002), Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 32:107-108.
-
(2002)
Nat Genet
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
70
-
-
33751251990
-
Small dsRNAs induce transcriptional activation in human cells
-
Li LC, Okino ST, Zhao H, Pookot D, Place RF, Urakami S, et al. (2006). Small dsRNAs induce transcriptional activation in human cells. Proc Natl Acad Sci USA 103:17337-17342.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17337-17342
-
-
Li, L.C.1
Okino, S.T.2
Zhao, H.3
Pookot, D.4
Place, R.F.5
Urakami, S.6
-
71
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. (2005). MicroRNA expression profiles classify human cancers. Nature 435:834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
-
72
-
-
25144498128
-
In vivo application of RNA interference: From functional genomics to therapeutics
-
Lu PY, Xie F, Woodle MC (2005). In vivo application of RNA interference: from functional genomics to therapeutics. Adv Genet 54:117-142.
-
(2005)
Adv Genet
, vol.54
, pp. 117-142
-
-
Lu, P.Y.1
Xie, F.2
Woodle, M.C.3
-
73
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U (2004). Nuclear export of microRNA precursors. Science 303:95-98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
74
-
-
34249804141
-
Protein i: Interference at protein level by inirabodies
-
Manikandan J, Pushparaj PN, Melendez AJ (2007). Protein i: interference at protein level by inirabodies. Front Biosci 12:1344-1352.
-
(2007)
Front Biosci
, vol.12
, pp. 1344-1352
-
-
Manikandan, J.1
Pushparaj, P.N.2
Melendez, A.J.3
-
75
-
-
36849026128
-
Applications of RNA interference in mammalian systems
-
Martin SE, Caplen NJ (2007). Applications of RNA interference in mammalian systems. Annu Rev Genomics Hum Genet 8:81-108.
-
(2007)
Annu Rev Genomics Hum Genet
, vol.8
, pp. 81-108
-
-
Martin, S.E.1
Caplen, N.J.2
-
76
-
-
0037032933
-
Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
-
Martinez MA, Gutierrez A, Armand-Ugon M, Blanco J, Parera M, Gomez J, et al. (2002). Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16:2385-2390.
-
(2002)
AIDS
, vol.16
, pp. 2385-2390
-
-
Martinez, M.A.1
Gutierrez, A.2
Armand-Ugon, M.3
Blanco, J.4
Parera, M.5
Gomez, J.6
-
77
-
-
27744590896
-
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
-
Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD (2005). Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123:607-620.
-
(2005)
Cell
, vol.123
, pp. 607-620
-
-
Matranga, C.1
Tomari, Y.2
Shin, C.3
Bartel, D.P.4
Zamore, P.D.5
-
78
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey AP, Nakai H, Pandey K, Huang Z, Salazar FH, Xu H, et al. (2003). Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol 21:63 9-644.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.63
, pp. 9-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
Huang, Z.4
Salazar, F.H.5
Xu, H.6
-
79
-
-
0345818258
-
MicroRNAs and cancer
-
McManus MT (2003). MicroRNAs and cancer. Semin Cancer Biol 13:253-258.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 253-258
-
-
McManus, M.T.1
-
80
-
-
35948948204
-
Inhibition of Fe epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes
-
Melendez AJ, Hamett MM, Pushparaj PN, Wong WS, Tay HR, McSharry CP, et al. (2007). Inhibition of Fe epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes. Nat Med 13:1375-1381.
-
(2007)
Nat Med
, vol.13
, pp. 1375-1381
-
-
Melendez, A.J.1
Hamett, M.M.2
Pushparaj, P.N.3
Wong, W.S.4
Tay, H.R.5
McSharry, C.P.6
-
81
-
-
3242733298
-
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
-
Minakuchi Y, Takcshita F, Kosaka N, Sasaki H, Yamamolo Y, Kouno M, et al. (2004). Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 32:e109.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Minakuchi, Y.1
Takcshita, F.2
Kosaka, N.3
Sasaki, H.4
Yamamolo, Y.5
Kouno, M.6
-
82
-
-
0018801485
-
Structural requirements of double-stranded RNA for the activation of 2′,5′-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells
-
Minks MA, West DK, Benvin S, Baglioni C (1979). Structural requirements of double-stranded RNA for the activation of 2′,5′-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells. J Biol Chem 254:10180-10183.
-
(1979)
J Biol Chem
, vol.254
, pp. 10180-10183
-
-
Minks, M.A.1
West, D.K.2
Benvin, S.3
Baglioni, C.4
-
83
-
-
0038301176
-
Long-term experience with GH replacement therapy: Efficacy and safety
-
Monson JP (2003). Long-term experience with GH replacement therapy: efficacy and safety. Eur J Endocrinol 148(Suppl 2):9-14.
-
(2003)
Eur J Endocrinol
, vol.148
, Issue.SUPPL. 2
, pp. 9-14
-
-
Monson, J.P.1
-
84
-
-
31344441137
-
A single-molecule method for the quantitation of microRNA gene expression
-
Neely LA, Patel S, Garver J, Gallo M, Hackett M, McLaughlin S, et al. (2006). A single-molecule method for the quantitation of microRNA gene expression. Nat Methods 3:41-46.
-
(2006)
Nat Methods
, vol.3
, pp. 41-46
-
-
Neely, L.A.1
Patel, S.2
Garver, J.3
Gallo, M.4
Hackett, M.5
McLaughlin, S.6
-
85
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway
-
Nykanen A, Haley B, Zamore PD (2001), ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107:309-321.
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
Haley, B.2
Zamore, P.D.3
-
86
-
-
33846845071
-
MicroRNA-155 is induced during the macrophage inflammatory response
-
O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D (2007). MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl A cad Sci USA 104:1604-1609.
-
(2007)
Proc Natl A cad Sci USA
, vol.104
, pp. 1604-1609
-
-
O'Connell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
Cheng, G.4
Baltimore, D.5
-
87
-
-
41149130219
-
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
-
O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nieoll J, et al. (2008). Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 205:585-594.
-
(2008)
J Exp Med
, vol.205
, pp. 585-594
-
-
O'Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
Boldin, M.P.4
Taganov, K.D.5
Nieoll, J.6
-
89
-
-
64149125745
-
-
Pitsch S, Weiss PA (2001). Chemical synthesis of RNA-sequences with 2′-0-[(triisopropylsilyl)oxy]methyT-protected ribonucleoside phosphoramidites (=TOM-phosphoramidites) (Unit 3.9). In: Current protocols of nucleic acid chemistry. Beaucagc S, editor. New York, NY: John Wiley & Sons, Inc.
-
Pitsch S, Weiss PA (2001). Chemical synthesis of RNA-sequences with 2′-0-[(triisopropylsilyl)oxy]methyT-protected ribonucleoside phosphoramidites (=TOM-phosphoramidites) (Unit 3.9). In: Current protocols of nucleic acid chemistry. Beaucagc S, editor. New York, NY: John Wiley & Sons, Inc.
-
-
-
-
90
-
-
0032884788
-
Fast and reliable automated synthesis of RNA and partially 2′-0-protccted precursors ("caged RNA") based on two novel, orthogonal 2′-0-protecting groups
-
Pitsch S, Weiss PA, Wu X, Ackermann D, Honegger T (1999). Fast and reliable automated synthesis of RNA and partially 2′-0-protccted precursors ("caged RNA") based on two novel, orthogonal 2′-0-protecting groups. Helv Chim Acta 82:1753-1761.
-
(1999)
Helv Chim Acta
, vol.82
, pp. 1753-1761
-
-
Pitsch, S.1
Weiss, P.A.2
Wu, X.3
Ackermann, D.4
Honegger, T.5
-
91
-
-
0035692119
-
Reliable chemical synthesis of oligoribonucleotides (RNA) with 2′-0-[(triisopropylsilyl) oxy]methyl (2′-0-TOM) protected phosphoramiditcs
-
Pitsch S, Weiss PA, Jenny L, Stutz A, Wu X (2001). Reliable chemical synthesis of oligoribonucleotides (RNA) with 2′-0-[(triisopropylsilyl) oxy]methyl (2′-0-TOM) protected phosphoramiditcs. Helv Chim Acta 84:3773-3795.
-
(2001)
Helv Chim Acta
, vol.84
, pp. 3773-3795
-
-
Pitsch, S.1
Weiss, P.A.2
Jenny, L.3
Stutz, A.4
Wu, X.5
-
92
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, et al. (2004). A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432:226-230.
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
Macdonald, P.E.6
-
93
-
-
35148819250
-
mieroRNAs and the regulation of glucose and lipid metabolism
-
Poy MN, Spranger M, Stoffel M (2007). mieroRNAs and the regulation of glucose and lipid metabolism. Diabetes Obes Metab 9(Suppl 2):67-73.
-
(2007)
Diabetes Obes Metab
, vol.9
, Issue.SUPPL. 2
, pp. 67-73
-
-
Poy, M.N.1
Spranger, M.2
Stoffel, M.3
-
96
-
-
49949152287
-
Refining siRNA in vivo transfection: Silencing SPHK1 reveals its key role in C5a-induced inflammation in vivo
-
Pushparaj PN, H'ng SC, Melendez AJ (2008b). Refining siRNA in vivo transfection: Silencing SPHK1 reveals its key role in C5a-induced inflammation in vivo. Int J Biochem Cell Biol 40:1817-1825.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1817-1825
-
-
Pushparaj, P.N.1
H'ng, S.C.2
Melendez, A.J.3
-
97
-
-
27744506761
-
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
-
Rand TA, Petersen S, Du F, Wang X (2005). Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123:621-629.
-
(2005)
Cell
, vol.123
, pp. 621-629
-
-
Rand, T.A.1
Petersen, S.2
Du, F.3
Wang, X.4
-
98
-
-
0036904741
-
Intravascular adenoviral agents in cancer patients: Lessons from clinical trials
-
Reid T, Warren R, Kirn D (2002). Intravascular adenoviral agents in cancer patients: lessons from clinical trials. Cancer Gene Ther 9:979-986.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 979-986
-
-
Reid, T.1
Warren, R.2
Kirn, D.3
-
99
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A, Leake D, Boese Q, Searinge S, Marshall WS, Khvorova A (2004). Rational siRNA design for RNA interference. Nat Biotechnol 22:326-330.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Searinge, S.4
Marshall, W.S.5
Khvorova, A.6
-
100
-
-
2542427517
-
GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allcle-specific small interfering RNA (siRNA)
-
Ryther RC, Flynt AS, Harris BD, Phillips JA 3rd, Patton JG (2004). GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allcle-specific small interfering RNA (siRNA). Endocrinology 145:2988-2996.
-
(2004)
Endocrinology
, vol.145
, pp. 2988-2996
-
-
Ryther, R.C.1
Flynt, A.S.2
Harris, B.D.3
Phillips 3rd, J.A.4
Patton, J.G.5
-
101
-
-
0036561252
-
Expression profiling of mammary carcinoma cell lines: Correlation of in vitro invasiveness with expression of CD24
-
Schindelmann S, Windisch J, Grundmann R, Kreienberg R, Zeillinger R, Deissler H (2002). Expression profiling of mammary carcinoma cell lines: correlation of in vitro invasiveness with expression of CD24. Tumour Biol 23:139-145.
-
(2002)
Tumour Biol
, vol.23
, pp. 139-145
-
-
Schindelmann, S.1
Windisch, J.2
Grundmann, R.3
Kreienberg, R.4
Zeillinger, R.5
Deissler, H.6
-
102
-
-
33645072440
-
Gene sequencing. The race for the $1000 genome
-
Service RF
-
Service RF (2006). Gene sequencing. The race for the $1000 genome. Science 311:1544-1546.
-
(2006)
Science
, vol.311
, pp. 1544-1546
-
-
-
103
-
-
33947207871
-
Reduction of CD44 expression results in growth inhibition of human nasopharyngeal carcinoma cell CNE-2L2 in vitro]
-
article in Chinese
-
Shi Y, Tian Y, Zhou YQ, Ju JY, Liu Y, Zhu LP (2007a). [Reduction of CD44 expression results in growth inhibition of human nasopharyngeal carcinoma cell CNE-2L2 in vitro]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 29:67-72 [article in Chinese].
-
(2007)
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
, vol.29
, pp. 67-72
-
-
Shi, Y.1
Tian, Y.2
Zhou, Y.Q.3
Ju, J.Y.4
Liu, Y.5
Zhu, L.P.6
-
104
-
-
34548527034
-
Inhibition of malignant activities of nasopharyngeal carcinoma cells with high expression of CD44 by siRNA
-
Shi Y, Tian Y, Zhou YQ, Ju JY, Qu L, Chen SL, et al. (2007b). Inhibition of malignant activities of nasopharyngeal carcinoma cells with high expression of CD44 by siRNA. Oncol Rep 18:397-403.
-
(2007)
Oncol Rep
, vol.18
, pp. 397-403
-
-
Shi, Y.1
Tian, Y.2
Zhou, Y.Q.3
Ju, J.Y.4
Qu, L.5
Chen, S.L.6
-
105
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas D, Lcrner C, Burehard J, Ge W, Linsley PS, Paddison PJ, et al. (2005). Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol 23:227-231.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 227-231
-
-
Siolas, D.1
Lcrner, C.2
Burehard, J.3
Ge, W.4
Linsley, P.S.5
Paddison, P.J.6
-
106
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoom DM, et al. (2005). Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 23:709-717.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 709-717
-
-
Song, E.1
Zhu, P.2
Lee, S.K.3
Chowdhury, D.4
Kussman, S.5
Dykxhoom, D.M.6
-
107
-
-
33744938416
-
Application of lentivirus-mediated RNAi in studying gene function in mammalian tooth development
-
Song Y, Zhang Z, Yu X, Yan M, Zhang X, Gu S, et al. (2006). Application of lentivirus-mediated RNAi in studying gene function in mammalian tooth development. Dev Dyn 235:1334-1344.
-
(2006)
Dev Dyn
, vol.235
, pp. 1334-1344
-
-
Song, Y.1
Zhang, Z.2
Yu, X.3
Yan, M.4
Zhang, X.5
Gu, S.6
-
108
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
Sorensen DR, Leirdal M, Sioud M (2003). Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J Mol Biol 327:761-766.
-
(2003)
J Mol Biol
, vol.327
, pp. 761-766
-
-
Sorensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
109
-
-
0037605839
-
Physiological and technological aspects of RNAi]
-
article in Japanese
-
Tabara H, Yasuda J (2003). [Physiological and technological aspects of RNAi]. Tanpakushitsu Kakusan Koso 48(4 Suppl):469-479 [article in Japanese].
-
(2003)
Tanpakushitsu Kakusan Koso
, vol.48
, Issue.4 SUPPL.
, pp. 469-479
-
-
Tabara, H.1
Yasuda, J.2
-
110
-
-
0037188904
-
The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans
-
Tabara H, Yigit E, Siomi H, Mello CC (2002). The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell 109:861-871.
-
(2002)
Cell
, vol.109
, pp. 861-871
-
-
Tabara, H.1
Yigit, E.2
Siomi, H.3
Mello, C.C.4
-
111
-
-
33747608638
-
NF-kappaB-dependenl induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006). NF-kappaB-dependenl induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sei USA 103:12481-12486.
-
(2006)
Proc Natl Acad Sei USA
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
112
-
-
33847311819
-
MieroRNAs and immunity: Tiny players in abig field
-
Taganov KD, Boldin MP, Baltimore D (2007). MieroRNAs and immunity: tiny players in abig field. Immunity 26:133-137.
-
(2007)
Immunity
, vol.26
, pp. 133-137
-
-
Taganov, K.D.1
Boldin, M.P.2
Baltimore, D.3
-
113
-
-
33745625836
-
Therapeutic potential of RNA interference against cancer
-
Takeshita F, Ochiya T (2006). Therapeutic potential of RNA interference against cancer. Cancer Sci 97:689-696.
-
(2006)
Cancer Sci
, vol.97
, pp. 689-696
-
-
Takeshita, F.1
Ochiya, T.2
-
114
-
-
24744464786
-
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
-
Takeshita F, Minakuchi Y, Nagahara S, Honma K, Sasaki H, Hirai K, et al. (2005). Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci USA 102:12177-12182.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12177-12182
-
-
Takeshita, F.1
Minakuchi, Y.2
Nagahara, S.3
Honma, K.4
Sasaki, H.5
Hirai, K.6
-
116
-
-
0038784432
-
Inducible systemic RNA silencing in Caenorhabditis elegans
-
Timmons L, Tabara H, Mello CC, Fire AZ (2003). Inducible systemic RNA silencing in Caenorhabditis elegans. Mol Biol Cell 14:2972-2983.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2972-2983
-
-
Timmons, L.1
Tabara, H.2
Mello, C.C.3
Fire, A.Z.4
-
117
-
-
33845317603
-
A signature pattern of stress-responsive mieroRNAs that can evoke cardiac hypertrophy and heart failure
-
van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, et al. (2006). A signature pattern of stress-responsive mieroRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci USA 103:18255-18260.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18255-18260
-
-
van Rooij, E.1
Sutherland, L.B.2
Liu, N.3
Williams, A.H.4
McAnally, J.5
Gerard, R.D.6
-
118
-
-
0036168787
-
HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans
-
Victor M, Bei Y, Gay F, Calvo D, Mello C, Shi Y (2002). HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans. EMBO Rep 3:50-55.
-
(2002)
EMBO Rep
, vol.3
, pp. 50-55
-
-
Victor, M.1
Bei, Y.2
Gay, F.3
Calvo, D.4
Mello, C.5
Shi, Y.6
-
119
-
-
18644380561
-
A critical role for sphingoslne kinase in anaphylatoxin-induced neutropenia, peritonitis, and cytokine production in vivo
-
Vlasenko LP, Melendez AJ (2005). A critical role for sphingoslne kinase in anaphylatoxin-induced neutropenia, peritonitis, and cytokine production in vivo. J Immunol 174:6456-6461.
-
(2005)
J Immunol
, vol.174
, pp. 6456-6461
-
-
Vlasenko, L.P.1
Melendez, A.J.2
-
120
-
-
30644473108
-
Antibody-directed cell-type-specific delivery of siRNA
-
Vomlocher HP (2006). Antibody-directed cell-type-specific delivery of siRNA. Trends Mol Med 12:1-3.
-
(2006)
Trends Mol Med
, vol.12
, pp. 1-3
-
-
Vomlocher, H.P.1
-
121
-
-
47049099443
-
Therapeutic gene silencing delivered by a chemically modified siRNA against mutant SOD1 slows ALS progression
-
Wang H, Ghosh A, Baigude H, Yang CS, Qiu L, Xia X, et al. (2008). Therapeutic gene silencing delivered by a chemically modified siRNA against mutant SOD1 slows ALS progression. J Biol Chetn 283:15845-15852.
-
(2008)
J Biol Chetn
, vol.283
, pp. 15845-15852
-
-
Wang, H.1
Ghosh, A.2
Baigude, H.3
Yang, C.S.4
Qiu, L.5
Xia, X.6
-
122
-
-
11844273868
-
RNA Interference in Caenorhabditis elegans
-
Wang J, Barr MM (2005). RNA Interference in Caenorhabditis elegans. Methods Enzymol 392:36-55.
-
(2005)
Methods Enzymol
, vol.392
, pp. 36-55
-
-
Wang, J.1
Barr, M.M.2
-
123
-
-
35748948383
-
Liver target delivery of small interfering RNA to the HCV gene by laetosylated eationie liposome
-
Watanabe T, Umehara T, Yasui F, Nakagawa SI, Yano J, Ohgi T, et al. (2007). Liver target delivery of small interfering RNA to the HCV gene by laetosylated eationie liposome. J Hepatol 47:744-750.
-
(2007)
J Hepatol
, vol.47
, pp. 744-750
-
-
Watanabe, T.1
Umehara, T.2
Yasui, F.3
Nakagawa, S.I.4
Yano, J.5
Ohgi, T.6
-
124
-
-
34250378330
-
MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts
-
Xiao J, Luo X, Lin H, Zhang Y, Lu Y, Wang N, et al. (2007). MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts. J Biol Chem 282:12363-12367.
-
(2007)
J Biol Chem
, vol.282
, pp. 12363-12367
-
-
Xiao, J.1
Luo, X.2
Lin, H.3
Zhang, Y.4
Lu, Y.5
Wang, N.6
-
125
-
-
32444445649
-
Harnessing in vivo siRNA delivery for drug discovery and therapeutic development
-
Xie FY, Woodle MC, Lu PY (2006). Harnessing in vivo siRNA delivery for drug discovery and therapeutic development. Drug Discov Today 11:67-73.
-
(2006)
Drug Discov Today
, vol.11
, pp. 67-73
-
-
Xie, F.Y.1
Woodle, M.C.2
Lu, P.Y.3
-
126
-
-
0035913721
-
Expression profile of active genes in human periodontal ligament and isolation of PLAP-1, a novel SLRP family gene
-
Yamada S, Murakami S, Matoba R, Ozawa Y, Yokokoji T, Nakahira Y, et al. (2001). Expression profile of active genes in human periodontal ligament and isolation of PLAP-1, a novel SLRP family gene. Gene 275:279-286.
-
(2001)
Gene
, vol.275
, pp. 279-286
-
-
Yamada, S.1
Murakami, S.2
Matoba, R.3
Ozawa, Y.4
Yokokoji, T.5
Nakahira, Y.6
-
127
-
-
34548181316
-
PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization
-
Yamada S, Tomoeda M, Ozawa Y, Yoneda S, Terashima Y, Ikezawa K, et al. (2007). PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization. J Biol Chem 282:23070-23080.
-
(2007)
J Biol Chem
, vol.282
, pp. 23070-23080
-
-
Yamada, S.1
Tomoeda, M.2
Ozawa, Y.3
Yoneda, S.4
Terashima, Y.5
Ikezawa, K.6
-
128
-
-
18844430787
-
Silencing of the p53R2 gene by RNA Interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells
-
Yanamoto S, Iwamoto T, Kawasaki G, Yoshitomi I, Baba N, Mizuno A (2005). Silencing of the p53R2 gene by RNA Interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells. Cancer Lett 223:67-76.
-
(2005)
Cancer Lett
, vol.223
, pp. 67-76
-
-
Yanamoto, S.1
Iwamoto, T.2
Kawasaki, G.3
Yoshitomi, I.4
Baba, N.5
Mizuno, A.6
-
129
-
-
34147095310
-
The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
-
Yang B, Lin H, Xiao J, Lu Y, Luo X, Li B, et al. (2007). The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med 13:486-491.
-
(2007)
Nat Med
, vol.13
, pp. 486-491
-
-
Yang, B.1
Lin, H.2
Xiao, J.3
Lu, Y.4
Luo, X.5
Li, B.6
-
130
-
-
33748300738
-
Regulation of E-eadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cells
-
Ye P, Nadkarni MA, Hunter N (2006). Regulation of E-eadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cells. Biochem Biophys Res Commun 349:229-235.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 229-235
-
-
Ye, P.1
Nadkarni, M.A.2
Hunter, N.3
-
131
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR (2003). Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17:3011 -3016.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
132
-
-
34548818764
-
Cationic lipids and polymers mediated vectors for delivery of siRNA
-
Zhang S, Zhao B, Jiang H, Wang B, Ma B (2007). Cationic lipids and polymers mediated vectors for delivery of siRNA. J Control Release 123:1-10.
-
(2007)
J Control Release
, vol.123
, pp. 1-10
-
-
Zhang, S.1
Zhao, B.2
Jiang, H.3
Wang, B.4
Ma, B.5
-
133
-
-
0035164784
-
Double-stranded RNA injection produces non-specific defects in zebrafish
-
Zhao Z, Cao Y, Li M, Meng A (2001). Double-stranded RNA injection produces non-specific defects in zebrafish. Dev Biol 229:215-223.
-
(2001)
Dev Biol
, vol.229
, pp. 215-223
-
-
Zhao, Z.1
Cao, Y.2
Li, M.3
Meng, A.4
-
134
-
-
22444437609
-
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
-
Zhao Y, Samal E, Srivastava D (2005). Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436:214-220.
-
(2005)
Nature
, vol.436
, pp. 214-220
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
-
135
-
-
34147153781
-
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1 -2
-
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, et al. (2007). Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1 -2. Cell 129:303-317.
-
(2007)
Cell
, vol.129
, pp. 303-317
-
-
Zhao, Y.1
Ransom, J.F.2
Li, A.3
Vedantham, V.4
von Drehle, M.5
Muth, A.N.6
|