Expression profiling of mammary carcinoma cell lines: Correlation of in vitro invasiveness with expression of CD24

Tumor Biology

Volumn 23, Issue 3, 2002, Pages 139-145

  Schindelmann, Sabine ^a   Windisch, Jasmin ^a   Grundmann, Regina ^a   Kreienberg, Rolf ^a   Zeillinger, Robert ^a,b   Deissler, Helmut ^a  

^a UNIVERSITY OF ULM MEDICAL SCHOOL   (Germany)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Breast cancer; CD24; Invasiveness; Microarray

Indexed keywords

CD24 ANTIGEN; CELL ADHESION MOLECULE; EZRIN RADIXIN MOESIN BINDING PHOSPHOPROTEIN 50; MEMBRANE ANTIGEN; MESSENGER RNA; PHOSPHOPROTEIN; RNA; VIMENTIN; CD24 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN;

ARTICLE; BREAST CANCER; BREAST CARCINOMA; CELL INVASION; CELL LINE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA MICROARRAY; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GOB 4 GENE; HUMAN; HUMAN CELL; HYBRIDIZATION; KERATIN 19 GENE; KERATIN 8 GENE; METASTASIS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL; TUMOR GROWTH; BREAST TUMOR; CANCER INVASION; CARCINOMA; CELL CULTURE; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTIGENS, CD; ANTIGENS, CD24; BREAST NEOPLASMS; CARCINOMA; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMANS; MEMBRANE GLYCOPROTEINS; NEOPLASM INVASIVENESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0036561252     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000064030     Document Type: Article

References (29)

1. Mareel M, Bracke M, van Roy F: Cancer metastasis: Negative regulation by an invasion-suppressor complex. Cancer Det Prev 1995;19:451-464.
2. Sgroi DC, Teng S, Robinson G, LeVangie R, Hudson JR, Elkahloun AG: In vivo gene expression profile analysis of human breast cancer progression. Cancer Res 1999;59:5656-5661.
3. Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, et al: Molecular portrait of human breast tumours. Nature 2000;406:747-752.
4. Yang GP, Ross DT, Kuang WW, Brown PO, Weigel RJ: Combining SSH and cDNA mieroarrays for rapid identification of differentially expressed genes. Nucleic Acids Res 1999;27:1517-1523.
5. Zajchowski DA, Bartholdi MF, Gong Y, Webster L, Liu H-L, Munishkin A, Beauheim C, Harvey S, Ethier SP, Johnson PH: Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells. Cancer Res 2001;61:5168-5178.
6. Tong D, Czerwenka K, Sedlak J, Schnecberger C, Schiebel I, Concin N, Leodolter S, Zeillinger R: Association of in vitro invasiveness and gene expression of estrogen receptor, progesterone receptor, pS2 and plasminogen activator inhibitor-1 in human breast cancer cell lines. Breast Cancer Res Treat 1999;56:91-97.
7. Church GM, Gilbert W: Genomic sequencing. Proc Natl Acad Sci USA 1984;81:1991-1995.
8. Bustin SA: Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 2000;25:169-193.
9. Fogel M, Friedrichs J, Zeller Y, Husar M, Smirnov A, Rotiman L, Altevogt P, Sthoeger ZM: CD24 is a marker for human breast carcinoma. Cancer Lett 1999;143:87-94.
10. Jackson D, Waibel R, Weber E, Bell J, Stahel RA: CD24. a signal-transducing molecule expressed on human B cells, is a major surface antigen on small cell lung carcinomas. Cancer Res 1992;52:5264-5270.
11. Ebener U, Wehner S, Cinatl J, Gussetis ES, Kornhuber B: Expression of markers shared between human haematopoietic cells and neuroblastoma cells. Anticancer Res 1990;10:887-890.
12. Droz D, Zachar D, Charbit L, Gogusev J, Chretein Y, Iris L: Expression of the human nephron differentiation molecules in renal cell carcinoma. Am J Pathol 1990;137:895-905.
13. Huang LR, Hsu HC: Cloning and expression of CD24 gene in human hepatocellular carcinoma: A potential early tumor marker gene correlates with p53 mutation and tumor differentiation. Cancer Res 1995;55:4717-4721.
14. Senner V, Sturm A, Baur I, Schrell UH, Distel L, Paulus W: CD24 promotes invasion of glioma cells in vivo. J Neuropathol Exp Neurol 1999;58:795-802.
15. Pirruccello SJ, LeBien TW: The human B cell-associated antigen CD24 is a single chain sialoglycoprotein. J Immunol 1986;136:3779-3784.
16. Kay R, Rosten PM, Humphries RK: CD24, a signal transducer modulating B cell activation responses, is a very short peptide with a glycosyl phosphatidylinositol membrane anchor. J Immunol 1991;147:1412-1416.
17. Aigner S, Sthoeger ZM, Fogel M, Weber E, Zarn J, Ruppert M, Zeller Y, Vestweber D, Stahel R, Sammar M, Altevogt P: CD24, a mucin-type glycoprotein, is a ligand for P-selectin on human tumor cells. Blood 1997;89:3385-3395.
18. Aigner S, Ramos CL, Hafezi-Moghadam A, Lawrence MB, Friedrichs J, Altevogt P, Ley K: CD24 mediates rolling of breast carcinoma cells on P-selectin. FASEB J 1998;12:1241-1251.
19. Bironaite D, Nesland JM, Dalen H, Risberg B, Bryne M: N-Glycans influence the in vitro adhesive and invasive behaviour of three metastatic cell lines. Tumor Biol 2000;21:165-175.
20. Friedrichs J, Zeller Y, Hafezi-Moghadam A, Gröne H-J, Ley K, Altevogt P: The CD24/P-selectin binding pathway initiates lung arrest of human A125 adenocarcinoma cells. Cancer Res 2000;60:6714-6722.
21. Kleene R, Yang H, Kutsche M, Schachner M: The neural recognition molecule L1 is a sialic acid-binding lectin for CD24, which induces promotion and inhibition of neurite outgrowth. J Biol Chem 2001;276:21656-21663.
22. Stefanova I, Horejsi, Ansotegui IJ, Knapp W, Stockinger H: GPI-anchored cell surface molecules complexed to protein tyrosine kinases. Science 1991;254:1016-1019.
23. Sammar M, Gulbins E, Hilbert K, Lang F, Altevogt P: Mouse CD24 is a signaling molecule for integrin-mediated cell binding: Functional and physical association with src-kinases. Biochem Biophys Res Commun 1997; 234:330-334.
24. Suzuki T, Kiyokawa N, Taguchi T, Sekino T, Katagiri YU, Fujimoto J: CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system. J Immunol 2001;166:5567-5577.
25. Mareel MM, De Bruyne GK, Vandesande F, Dragonetti C: Immunohistochemical study of embryonic chick heart invaded by malignant cells in three-dimensional culture. Invasion Metastasis 1981;1:195-204.
26. Thompson EW, Yu M, Bueno J, Jin L, Maiti SN, Palao-Marco FL, Pulyaeva H, Tamborlane JW, Tirgari R, Wapnir I, et al: Collagen induced MMP-2 activation in human breast cancer. Breast Cancer Res Treat 1994;31:357-370.
27. Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al: Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001;98:10869-10874.
28. Thompson DA, Weigel RJ: HAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines. Biochem Biophys Res Commun 1998;251:111-116.
29. Bretscher A, Chambers D, Nguyen R, Recek D: ERM-Merlin and EBP50 protein families in plasma membrane organization and function. Annu Rev Cell Dev Biol 2000;16:113-143.