The rest is silence

RNA

Volumn 7, Issue 11, 2001, Pages 1509-1521

  Bernstein, Emily ^a,b   Denli, Ahmet M ^a   Hannon, Gregory J ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA;

CAENORHABDITIS ELEGANS; GENE AMPLIFICATION; GENE SILENCING; GENETIC ANALYSIS; GENOME; NEUROSPORA CRASSA; NONHUMAN; PLANT; PRIORITY JOURNAL; REVIEW; RNA ANALYSIS; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION; TRANSGENE;

ANIMALS; GENE SILENCING; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; RNA, UNTRANSLATED; TRANSGENES;

EID: 0035169953     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (103)

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11. Asemi-dominant allele, niv-525, acts in trans to inhibit expression of its wild-type homologue in Antirrhinum majus
12. Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
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14. Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
15. Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase
16. Interchromosomal transfer of epigenetic states in Ascobolus: Transfer of DNA methylation is mechanistically related to homologous recombination
17. A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal
18. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
19. SDE3 encodes an RNA helicase required for posttranscriptional gene silencing in Arabidopsis
20. Suppression of beta-1,3-glucanase transgene expression in homozygous plants
21. Transgene-mediated cosuppression in the C. elegans germ line
22. Cytosine methylation at CG and CNG sites is not a prerequisite for the initiation of transcriptional gene silencing in plants, but it is required for its maintenance
23. Emerging connections between DNA methylation and histone acetylation
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26. Arabidopsis mutants impaired in cosuppression
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30. Production of antisense RNA leads to effective and specific inhibition of gene expression in C. elegans muscle
31. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
32. Gene silencing and homology-dependent gene silencing in Arabidopsis: Genetic modifiers and DNA methylation
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34. Targeted transformation of Ascobolus immersus and de novo methylation of the resulting duplicated DNA sequences
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39. An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells
40. Posttranscriptional gene silencing by double-stranded RNA
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42. Silencing of retrotransposons in Arabidopsis and reactivation by the ddml mutation
43. Stochastic and nonstochastic posttranscriptional silencing of chitinase and beta-1,3-glucanase genes involves increased RNA turnover-possible role for ribosome-independent RNA degradation
44. A cellular function for the rna-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
45. Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation
46. Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems
47. Molecular and cytogenetic characterization of a transgene locus that induces silencing and methylation of homologous promoters in trans
48. The DNA methylation locus DDM1 is required for maintenance of gene silencing in Arabidopsis
49. Maintenance of genomic methylation requires a SW12/SNF2-like protein
50. Taming of transposable elements by homology-dependent gene silencing
51. RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance
52. Altered gene expression in plants due to trans interactions between homologous genes
53. Characterization of an Arabidopsis thaliana DNA hypomethylation mutant
54. Posttranscriptional gene silencing in cultured rice cells
55. Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily
56. Chromatin silencing and the maintenance of a functional germline in Caenorhabditis elegans
57. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
58. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
59. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in C. elegans
60. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
61. Plasmodesmata: Intercellular channels for macromolecular transport in plants
62. Selective trafficking of Knotted1 homeodomain protein and its mRNA through plasmodesmata
63. DNA methylation in Drosophila melanogaster
64. The Pinhead/Zwille gene acts pleiotropically in Arabidopsis development and has overlapping functions with the Argonaute1 gene
65. HC-Pro suppression of transgene silencing eliminates the small RNAs but not transgene methylation or the mobile signal
66. Quality control of mRNA function
67. Transcriptional silencing and promoter methylation triggered by double-stranded RNA
68. Production of aberrant promoter transcripts contributes to methylation and silencing of unlinked homologous promoters in trans
69. Transcriptional transgene silencing and chromatin components
70. Differences in DNA-methylation are associated with a paramutation phenomenon in transgenic petunia
71. Mobilization of transposons by a mutation abolishing full DNA methylation in Arabidopsis
72. DNA methylation and chromatin structure affect transcriptional and post transcriptional transgene silencing in Arabidopsis
73. Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
74. Role of the Zwille gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis
75. Role of inverted DNA repeats in transcriptional and post transcriptional gene silencing
76. Systemic acquired silencing: Transgene-specific posttranscriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions
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78. Functional anatomy of a dsRNA trigger. Differential requirement for the two trigger strands in RNA interference
79. Paramutation, an allelic interaction, is associated with a stable and heritable reduction of transcription of the maize b regulatory gene
80. A DNA target of 30 bp is sufficient for RNA-directed DNA methylation
81. Polycombing the genome: PcG, trxG, and chromatin silencing
82. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
83. Epimutation of repeated genes in Ascobolus immersus
84. Histone methylation versus histone acetylation: New insights into epigenetic regulation
85. Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
86. Homology-dependent gene silencing in Paramecium
87. Genetic and molecular characterization of sting, a gene involved in crystal formation and meiotic drive in the male germ line of Drosophila melanogaster
88. Epigenetic phenomena in filamentous fungi: Useful paradigms or repeat-induced confusion?
89. Posttranscriptional gene-silencing: RNAs on the attack or on the defense?
90. Robertson's mutator transposons in A. thaliana are regulated by the chromatin-remodeling gene decrease in DNA methylation (DDM1)
91. EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans
92. Distinct features of posttranscriptional gene silencing by antisense transgenes in single copy and inverted T-DNA repeat loci
93. The rde-1 gene, RNA interference, and transposon silencing in C. elegans
94. Specific interference by ingested dsRNA
95. Targeted mRNA degradation by double-stranded RNA in vitro
96. Maintenance of genomic imprinting at the Arabidopsis medea locus requires zygotic DDM1 activity
97. Systemic signalling in gene silencing
98. A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana
99. RNA-directed de novo methylation of genomic sequences in plants
100. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
101. Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-box RNA helicase
102. Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos
103. RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals