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Volumn 123, Issue 1, 2007, Pages 1-10

Cationic lipids and polymers mediated vectors for delivery of siRNA

Author keywords

Cationic lipids; Cationic liposomes; Polymer nanoparticles; RNAi; siRNA

Indexed keywords

CATIONIC LIPIDS; CATIONIC LIPOSOMES; NON-VIRAL VECTORS; POLYMER NANOPARTICLES;

EID: 34548818764     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.07.016     Document Type: Review
Times cited : (398)

References (109)
  • 1
    • 0032417618 scopus 로고    scopus 로고
    • RNA as a target of double stranded RNA-mediated genetic interference in Caenorhabditis elegans
    • Montgomery M.K., Xu S., and Fire A. RNA as a target of double stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 15502-15507
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 15502-15507
    • Montgomery, M.K.1    Xu, S.2    Fire, A.3
  • 2
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., and Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 (1998) 806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 3
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo S., and Kemphues K.J. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81 (1995) 611-620
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 6
    • 15544377122 scopus 로고    scopus 로고
    • RNAi as an experimental and therapeutic tool to study and regulate physiological and disease processes
    • Dillon C.P., Sandy P., Nencioni A., Kissler S., Rubinson D.A., and Van Parijs L. RNAi as an experimental and therapeutic tool to study and regulate physiological and disease processes. Annu. Rev. Physiol. 67 (2005) 147-173
    • (2005) Annu. Rev. Physiol. , vol.67 , pp. 147-173
    • Dillon, C.P.1    Sandy, P.2    Nencioni, A.3    Kissler, S.4    Rubinson, D.A.5    Van Parijs, L.6
  • 7
  • 8
    • 21344457432 scopus 로고    scopus 로고
    • RNA interference: from gene silencing to gene-specific therapeutics
    • Leung P.K., and Whittaker P.A. RNA interference: from gene silencing to gene-specific therapeutics. Pharmacol. Ther. 107 (2005) 222-239
    • (2005) Pharmacol. Ther. , vol.107 , pp. 222-239
    • Leung, P.K.1    Whittaker, P.A.2
  • 10
    • 0026497428 scopus 로고
    • Effect of cationic cholesterol derivatives on gene transfer and protein kinase C activity
    • Farhood H., Bottega R., Epand R.M., and Huang L. Effect of cationic cholesterol derivatives on gene transfer and protein kinase C activity. Biochim. Biophys. Acta 1111 (1992) 239-246
    • (1992) Biochim. Biophys. Acta , vol.1111 , pp. 239-246
    • Farhood, H.1    Bottega, R.2    Epand, R.M.3    Huang, L.4
  • 11
    • 2442534371 scopus 로고    scopus 로고
    • Transfection efficiency and cytotoxicity of cationic liposomes in salmonid cell lines of hepatocyte and macrophage origin
    • Romoren K., Thu B.J., Bols N.C., and Evensen O. Transfection efficiency and cytotoxicity of cationic liposomes in salmonid cell lines of hepatocyte and macrophage origin. Biochim. Biophys. Acta 1663 (2004) 127-134
    • (2004) Biochim. Biophys. Acta , vol.1663 , pp. 127-134
    • Romoren, K.1    Thu, B.J.2    Bols, N.C.3    Evensen, O.4
  • 12
    • 33750288634 scopus 로고    scopus 로고
    • Corona-stabilized interpolyelectrolyte complexes of siRNA with nonimmunogenic, hydrophilic/cationic block copolymers prepared by aqueous RAFT polymerization
    • Scales C.W., Huang F., Li N., Vasilieva Y.A., Ray J., Convertine A.J., and McCormick C.L. Corona-stabilized interpolyelectrolyte complexes of siRNA with nonimmunogenic, hydrophilic/cationic block copolymers prepared by aqueous RAFT polymerization. Macromolecules 39 (2006) 6871-6881
    • (2006) Macromolecules , vol.39 , pp. 6871-6881
    • Scales, C.W.1    Huang, F.2    Li, N.3    Vasilieva, Y.A.4    Ray, J.5    Convertine, A.J.6    McCormick, C.L.7
  • 13
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • Napoli C., Lemieux C., and Jorgensen R. Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2 (1990) 279-289
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 14
  • 16
    • 0037123639 scopus 로고    scopus 로고
    • RNA-dependent RNA polymerases, viruses, and RNA silencing
    • Ahlquist P. RNA-dependent RNA polymerases, viruses, and RNA silencing. Science 296 (2002) 1270-1273
    • (2002) Science , vol.296 , pp. 1270-1273
    • Ahlquist, P.1
  • 19
    • 0034683099 scopus 로고    scopus 로고
    • Sensitive assay of RNA interfernce in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
    • Ui-Tei K., Zenno S., Miyata Y., and Saigo K. Sensitive assay of RNA interfernce in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS Lett. 479 (2000) 79-82
    • (2000) FEBS Lett. , vol.479 , pp. 79-82
    • Ui-Tei, K.1    Zenno, S.2    Miyata, Y.3    Saigo, K.4
  • 20
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny F., and Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell. Biol. 2 (2000) 70-75
    • (2000) Nat. Cell. Biol. , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 22
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis D.L., Hagstrom J.E., Loomis A.G., Wolff J.A., and Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32 (2002) 107-108
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 24
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore P.D., Tuschl T., Sharp P.A., and Bartel D.P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101 (2000) 25-33
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 25
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E., Caudy A.A., Hammond S.M., and Hannon G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409 (2001) 363-366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 26
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., and Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411 (2001) 494-498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 27
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21-and 22-nucleotide RNAs
    • Elbashir S.M., Lendeckel W., and Tuschl T. RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev. 15 (2001) 188-200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 28
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir S.M., Martinez J., Patkaniowska A., Lendeckel W., and Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20 (2001) 6877-6888
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 29
    • 1842715778 scopus 로고    scopus 로고
    • Dicer at RISC: the mechanism of RNAi
    • Tijsterman M., and Plasterk R.H.A. Dicer at RISC: the mechanism of RNAi. Cell 117 (2004) 1-3
    • (2004) Cell , vol.117 , pp. 1-3
    • Tijsterman, M.1    Plasterk, R.H.A.2
  • 32
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., and Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75 (1993) 843-854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 33
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner G., McLachlan J., Pasquinelli A.E., Balint E., Tuschl T., and Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293 (2001) 834-838
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 35
    • 34248643411 scopus 로고    scopus 로고
    • Evaluation of polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) as a novel carrier for small interfering RNA (siRNA)
    • Tsutsumi T., Hirayama F., Uekama K., and Arima H. Evaluation of polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) as a novel carrier for small interfering RNA (siRNA). J. Control. Release 119 (2007) 349-359
    • (2007) J. Control. Release , vol.119 , pp. 349-359
    • Tsutsumi, T.1    Hirayama, F.2    Uekama, K.3    Arima, H.4
  • 37
    • 0242526935 scopus 로고    scopus 로고
    • RNA interference: on the road to an alternate therapeutic strategy
    • Dave R.S., and Pomerantz R.J. RNA interference: on the road to an alternate therapeutic strategy. Rev. Med. Virol. 13 (2003) 373-385
    • (2003) Rev. Med. Virol. , vol.13 , pp. 373-385
    • Dave, R.S.1    Pomerantz, R.J.2
  • 38
    • 1642498310 scopus 로고    scopus 로고
    • Pharmaceutical prospects for RNA interference
    • Schiffelers R.M., Woodle M.C., and Scaria P. Pharmaceutical prospects for RNA interference. Pharm. Res. 21 (2004) 1-7
    • (2004) Pharm. Res. , vol.21 , pp. 1-7
    • Schiffelers, R.M.1    Woodle, M.C.2    Scaria, P.3
  • 40
    • 33846846570 scopus 로고    scopus 로고
    • Liposomes for phospholipase A2 triggered siRNA release: Preparation and in vitro test
    • Foged C., Nielsen H.M., and Frokjaer S. Liposomes for phospholipase A2 triggered siRNA release: Preparation and in vitro test. Int. J. Pharm. 331 (2007) 160-166
    • (2007) Int. J. Pharm. , vol.331 , pp. 160-166
    • Foged, C.1    Nielsen, H.M.2    Frokjaer, S.3
  • 41
    • 21744437897 scopus 로고    scopus 로고
    • Synergistic effect of poly (ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes
    • Kim T.H., Kim S.I., Akaike T., and Cho C.S. Synergistic effect of poly (ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes. J. Control. Release 105 (2005) 354-366
    • (2005) J. Control. Release , vol.105 , pp. 354-366
    • Kim, T.H.1    Kim, S.I.2    Akaike, T.3    Cho, C.S.4
  • 42
    • 33749844509 scopus 로고    scopus 로고
    • Development and characterisation of chitosan nanoparticles for siRNA delivery
    • Katas H., and Alpar H.O. Development and characterisation of chitosan nanoparticles for siRNA delivery. J. Control. Release 115 (2006) 216-225
    • (2006) J. Control. Release , vol.115 , pp. 216-225
    • Katas, H.1    Alpar, H.O.2
  • 43
    • 6344291687 scopus 로고    scopus 로고
    • Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA
    • Spagnou S., Miller A.D., and Keller M. Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA. Biochemistry 43 (2004) 13348-13356
    • (2004) Biochemistry , vol.43 , pp. 13348-13356
    • Spagnou, S.1    Miller, A.D.2    Keller, M.3
  • 45
    • 2342530994 scopus 로고    scopus 로고
    • Advanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applications
    • Dalby B., Cates S., Harris A., Ohki E.C., Tilkins M.L., Price P.J., and Ciccarone V.C. Advanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applications. Methods 33 (2004) 95-103
    • (2004) Methods , vol.33 , pp. 95-103
    • Dalby, B.1    Cates, S.2    Harris, A.3    Ohki, E.C.4    Tilkins, M.L.5    Price, P.J.6    Ciccarone, V.C.7
  • 46
    • 4444220551 scopus 로고    scopus 로고
    • Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells
    • Lorenz C., Hadwiger P., John M., Vornlocher H.P., and Unverzagt C. Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells. Bioorg. Med. Chem. Lett. 14 (2004) 4975-4977
    • (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 4975-4977
    • Lorenz, C.1    Hadwiger, P.2    John, M.3    Vornlocher, H.P.4    Unverzagt, C.5
  • 47
    • 33745014998 scopus 로고    scopus 로고
    • Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis
    • Khoury M., Louis-Plence P., Escriou V., Noel D., Largeau C., Cantos C., Scherman D., Jorgensen C., and Apparailly F. Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis. Arthritis Rheum. 54 (2006) 1867-1877
    • (2006) Arthritis Rheum. , vol.54 , pp. 1867-1877
    • Khoury, M.1    Louis-Plence, P.2    Escriou, V.3    Noel, D.4    Largeau, C.5    Cantos, C.6    Scherman, D.7    Jorgensen, C.8    Apparailly, F.9
  • 49
    • 15444376742 scopus 로고    scopus 로고
    • Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivo
    • Flynn M.A., Casey D.G., Todryk S.M., and Mahon B.P. Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivo. J. Inflam. 1 (2004) 1-4
    • (2004) J. Inflam. , vol.1 , pp. 1-4
    • Flynn, M.A.1    Casey, D.G.2    Todryk, S.M.3    Mahon, B.P.4
  • 50
    • 0344926320 scopus 로고    scopus 로고
    • Cationic liposome-mediated delivery of siRNAs in adult mice
    • Sioud M., and Søensen D.R. Cationic liposome-mediated delivery of siRNAs in adult mice. Biochem. Biophys. Res. Commun. 312 (2003) 1220-1225
    • (2003) Biochem. Biophys. Res. Commun. , vol.312 , pp. 1220-1225
    • Sioud, M.1    Søensen, D.R.2
  • 51
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • Sorensen D.R., Leirdal M., and Sioud M. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 327 (2003) 761-766
    • (2003) J. Mol. Biol. , vol.327 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 55
    • 33845654382 scopus 로고    scopus 로고
    • Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice
    • Sato A., Takagi M., Shimamoto A., Kawakami S., and Hashid M. Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice. Biomaterials 28 (2007) 1434-1442
    • (2007) Biomaterials , vol.28 , pp. 1434-1442
    • Sato, A.1    Takagi, M.2    Shimamoto, A.3    Kawakami, S.4    Hashid, M.5
  • 56
    • 33749267037 scopus 로고    scopus 로고
    • Liposome-mediated RNA transfection should be used with caution
    • Barreau C., Dutertre S., Pailiard L., and Osborne H.B. Liposome-mediated RNA transfection should be used with caution. RNA 12 (2006) 1790-1793
    • (2006) RNA , vol.12 , pp. 1790-1793
    • Barreau, C.1    Dutertre, S.2    Pailiard, L.3    Osborne, H.B.4
  • 57
    • 0035930615 scopus 로고    scopus 로고
    • Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the β 1,3-galatosyltransferase family (β 3GalT6)
    • Bai X.M., Zhou D.P., Brown J.R., Crawford B.E., Hennet T., and Esko J.D. Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the β 1,3-galatosyltransferase family (β 3GalT6). J. Biol. Chem. 276 (2001) 48189-48195
    • (2001) J. Biol. Chem. , vol.276 , pp. 48189-48195
    • Bai, X.M.1    Zhou, D.P.2    Brown, J.R.3    Crawford, B.E.4    Hennet, T.5    Esko, J.D.6
  • 58
    • 0037666792 scopus 로고    scopus 로고
    • Conditional knock-out of integrin-linked kinase (ILK) demonstrates an essential role in PKB/Akt activation
    • Troussard A.A., Mawji N.M., Ong C., Mui A., St.-Arnaud R., and Dedhar S. Conditional knock-out of integrin-linked kinase (ILK) demonstrates an essential role in PKB/Akt activation. J. Biol. Chem. 278 (2003) 22374-22378
    • (2003) J. Biol. Chem. , vol.278 , pp. 22374-22378
    • Troussard, A.A.1    Mawji, N.M.2    Ong, C.3    Mui, A.4    St.-Arnaud, R.5    Dedhar, S.6
  • 59
    • 0141988726 scopus 로고    scopus 로고
    • Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation
    • Leu Y.W., Rahmatpanah F., Shi H.D., Wei S.H., Liu J.C., Yan P.S., and Hui-Ming Huang T. Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. Cancer Res. 63 (2003) 6110-6115
    • (2003) Cancer Res. , vol.63 , pp. 6110-6115
    • Leu, Y.W.1    Rahmatpanah, F.2    Shi, H.D.3    Wei, S.H.4    Liu, J.C.5    Yan, P.S.6    Hui-Ming Huang, T.7
  • 60
    • 0036311178 scopus 로고    scopus 로고
    • Gene silencing in mammalian cells by preformed small RNA duplexes
    • Leirdal M., and Sioud M. Gene silencing in mammalian cells by preformed small RNA duplexes. Biochem. Biophys. Res. Commun. 295 (2002) 744-748
    • (2002) Biochem. Biophys. Res. Commun. , vol.295 , pp. 744-748
    • Leirdal, M.1    Sioud, M.2
  • 61
    • 33750405780 scopus 로고    scopus 로고
    • Kinetic and efficacy analysis of RNA interference in stably and transiently expressing cell lines
    • Richards Grayson A.C., Ma J., and Putnam D. Kinetic and efficacy analysis of RNA interference in stably and transiently expressing cell lines. Mol. Pharmaceutics 3 (2006) 601-613
    • (2006) Mol. Pharmaceutics , vol.3 , pp. 601-613
    • Richards Grayson, A.C.1    Ma, J.2    Putnam, D.3
  • 64
    • 0033122136 scopus 로고    scopus 로고
    • Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes
    • Van de Wetering P., Schuurmans-Nieuwenbroek N.M., Hennink W.E., and Storm G. Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. J. Gene Med. 1 (1999) 156-165
    • (1999) J. Gene Med. , vol.1 , pp. 156-165
    • Van de Wetering, P.1    Schuurmans-Nieuwenbroek, N.M.2    Hennink, W.E.3    Storm, G.4
  • 65
    • 0032473546 scopus 로고    scopus 로고
    • Interpolyelectrolyte and block ionomer complexes for gene delivery: physico-chemical aspects
    • Kabanov V.A., and Kabanov A.V. Interpolyelectrolyte and block ionomer complexes for gene delivery: physico-chemical aspects. Adv. Drug Deliv. Rev. 30 (1998) 49-60
    • (1998) Adv. Drug Deliv. Rev. , vol.30 , pp. 49-60
    • Kabanov, V.A.1    Kabanov, A.V.2
  • 66
    • 0029801424 scopus 로고    scopus 로고
    • Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers
    • Wolfert M.A., Schaht E.H., Tonceva V., Ulbrich K., Nazarova O., and Seymour L.W. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum. Gene Ther. 7 (1996) 2123-2133
    • (1996) Hum. Gene Ther. , vol.7 , pp. 2123-2133
    • Wolfert, M.A.1    Schaht, E.H.2    Tonceva, V.3    Ulbrich, K.4    Nazarova, O.5    Seymour, L.W.6
  • 67
    • 0031938986 scopus 로고    scopus 로고
    • Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(l-lysine) block copolymer
    • Katayose S., and Kataoka K. Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(l-lysine) block copolymer. J. Pharm. Sci. 87 (1998) 160-163
    • (1998) J. Pharm. Sci. , vol.87 , pp. 160-163
    • Katayose, S.1    Kataoka, K.2
  • 68
    • 0032211994 scopus 로고    scopus 로고
    • Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules
    • Wang L., Kristensen J., and Ruffner D.E. Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules. Bioconjug. Chem. 9 (1998) 749-757
    • (1998) Bioconjug. Chem. , vol.9 , pp. 749-757
    • Wang, L.1    Kristensen, J.2    Ruffner, D.E.3
  • 69
    • 0242585472 scopus 로고    scopus 로고
    • The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells
    • (Article 32)
    • Jensen K.D., Kopeckova P., Bridge J.H.B., and Kopecek J. The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells. AAPS PharmSci 3 (2001) (Article 32)
    • (2001) AAPS PharmSci , vol.3
    • Jensen, K.D.1    Kopeckova, P.2    Bridge, J.H.B.3    Kopecek, J.4
  • 70
    • 31544441351 scopus 로고    scopus 로고
    • Coating of DNA/poly(l-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide]
    • Subr V., Konak C., Laga R., and Ulbrich K. Coating of DNA/poly(l-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide]. Biomacromolecules 7 (2006) 122-130
    • (2006) Biomacromolecules , vol.7 , pp. 122-130
    • Subr, V.1    Konak, C.2    Laga, R.3    Ulbrich, K.4
  • 72
    • 78650476432 scopus 로고    scopus 로고
    • The proton sponge: a trick to enter cells the viruses did not exploit
    • Behr J.P. The proton sponge: a trick to enter cells the viruses did not exploit. Chimia 51 (1997) 34-36
    • (1997) Chimia , vol.51 , pp. 34-36
    • Behr, J.P.1
  • 74
    • 0034609633 scopus 로고    scopus 로고
    • Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery
    • Godbey W.T., Barry M.A., Saggau P., Wu K.K., and Mikos A.G. Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery. J. Biomed. Mater. Res. 51 (2000) 321-328
    • (2000) J. Biomed. Mater. Res. , vol.51 , pp. 321-328
    • Godbey, W.T.1    Barry, M.A.2    Saggau, P.3    Wu, K.K.4    Mikos, A.G.5
  • 75
    • 0030729180 scopus 로고    scopus 로고
    • Exgen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo
    • Ferrari S., Moro E., Pettenazzo A., Behr J.P., Zacchello F., and Scarpa M. Exgen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo. Gene Ther. 4 (1997) 1100-1106
    • (1997) Gene Ther. , vol.4 , pp. 1100-1106
    • Ferrari, S.1    Moro, E.2    Pettenazzo, A.3    Behr, J.P.4    Zacchello, F.5    Scarpa, M.6
  • 76
    • 0031860769 scopus 로고    scopus 로고
    • size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system
    • Goula D., Remy J.S., Erbacher P., Wasowicz M., Levi G., Abdallah B., and Demeneix B.A. size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system. Gene Ther. 5 (1998) 712-717
    • (1998) Gene Ther. , vol.5 , pp. 712-717
    • Goula, D.1    Remy, J.S.2    Erbacher, P.3    Wasowicz, M.4    Levi, G.5    Abdallah, B.6    Demeneix, B.A.7
  • 78
    • 0033621041 scopus 로고    scopus 로고
    • Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of Crigler-Najjar syndrome type I with a chimeric oligonucleotide
    • Kren B.T., Parashar B., Bandyopadhyay P., Chowdhury N.R., Chowdhury J.R., and Steer C.J. Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of Crigler-Najjar syndrome type I with a chimeric oligonucleotide. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 10349-10354
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 10349-10354
    • Kren, B.T.1    Parashar, B.2    Bandyopadhyay, P.3    Chowdhury, N.R.4    Chowdhury, J.R.5    Steer, C.J.6
  • 79
    • 0031788165 scopus 로고    scopus 로고
    • The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
    • Ogris M., Steinlein P., Kursa M., Mechtler K., Kircheis R., and Wagner E. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. 5 (1998) 1425-1433
    • (1998) Gene Ther. , vol.5 , pp. 1425-1433
    • Ogris, M.1    Steinlein, P.2    Kursa, M.3    Mechtler, K.4    Kircheis, R.5    Wagner, E.6
  • 82
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M., Brunner S., Schuller S., Kiacheis R., and Wagner E. PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6 (1999) 595-605
    • (1999) Gene Ther. , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kiacheis, R.4    Wagner, E.5
  • 85
    • 17644418754 scopus 로고    scopus 로고
    • Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung
    • Thomas M., Lu J.J., Ge Q., Zhang C., Chen J., and Klibanov A.M. Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 5679-5684
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 5679-5684
    • Thomas, M.1    Lu, J.J.2    Ge, Q.3    Zhang, C.4    Chen, J.5    Klibanov, A.M.6
  • 86
    • 33646152761 scopus 로고    scopus 로고
    • A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes
    • Werth S., Urban-Klein B., Dai L., Höbel S., Grzelinski M., Bakowsky U., Czubayko F., and Aigner A. A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes. J. Control. Release 112 (2006) 257-270
    • (2006) J. Control. Release , vol.112 , pp. 257-270
    • Werth, S.1    Urban-Klein, B.2    Dai, L.3    Höbel, S.4    Grzelinski, M.5    Bakowsky, U.6    Czubayko, F.7    Aigner, A.8
  • 88
    • 33748994569 scopus 로고    scopus 로고
    • Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/siRNA polyplexes
    • Mao S., Neu M., Germershaus O., Merkel O., Sitterberg J., Bakowsky U., and Kissel T. Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/siRNA polyplexes. Bioconjug. Chem. 17 (2006) 1209-1218
    • (2006) Bioconjug. Chem. , vol.17 , pp. 1209-1218
    • Mao, S.1    Neu, M.2    Germershaus, O.3    Merkel, O.4    Sitterberg, J.5    Bakowsky, U.6    Kissel, T.7
  • 89
    • 2942530436 scopus 로고    scopus 로고
    • Inhibition of influenza virus production in virus-infected mice by RNA interference
    • Ge Q., Filip L., Bai A., Nguyen T., Eisen H.N., and Chen J. Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 8676-8681
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 8676-8681
    • Ge, Q.1    Filip, L.2    Bai, A.3    Nguyen, T.4    Eisen, H.N.5    Chen, J.6
  • 90
    • 15444373116 scopus 로고    scopus 로고
    • A. Aigner. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
    • Urban-Klein B., Werth S., Abuharbeid S., and Czubayko F. A. Aigner. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther. 12 (2005) 461-466
    • (2005) Gene Ther. , vol.12 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3    Czubayko, F.4
  • 92
    • 1842843556 scopus 로고    scopus 로고
    • The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release
    • Shu X.Z., and Zhu K.J. The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release. Eur. J. Pharm. Biopharm. 54 (2002) 235-243
    • (2002) Eur. J. Pharm. Biopharm. , vol.54 , pp. 235-243
    • Shu, X.Z.1    Zhu, K.J.2
  • 94
    • 1942470953 scopus 로고    scopus 로고
    • K.W. Leong. The effect of the degree of chitosan deacetylation on the efficiency of gene transfection
    • Kiang T., Wen J., and Lim H.W. K.W. Leong. The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. Biomaterials 25 (2004) 5293-5301
    • (2004) Biomaterials , vol.25 , pp. 5293-5301
    • Kiang, T.1    Wen, J.2    Lim, H.W.3
  • 95
    • 10044287286 scopus 로고    scopus 로고
    • An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes
    • Liu W., Sun S., Cao Z., Zhang X., Yao K., Lu W.W., and Luk K.D. An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes. Biomaterials 26 (2005) 2705-2711
    • (2005) Biomaterials , vol.26 , pp. 2705-2711
    • Liu, W.1    Sun, S.2    Cao, Z.3    Zhang, X.4    Yao, K.5    Lu, W.W.6    Luk, K.D.7
  • 100
    • 0343938838 scopus 로고    scopus 로고
    • DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers
    • Oupicky D., Konak C., Ulbrich K., Wolfert M.A., and Seymour L.W. DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers. J. Control. Release 65 (2000) 149-171
    • (2000) J. Control. Release , vol.65 , pp. 149-171
    • Oupicky, D.1    Konak, C.2    Ulbrich, K.3    Wolfert, M.A.4    Seymour, L.W.5
  • 101
    • 85047695467 scopus 로고    scopus 로고
    • Polyion complex micelles as vectors in gene therapy-pharmacokinetics and in vivo gene transfer
    • Harada-Shiba M., Yamauchi K., Harada A., Takamisawa I., Shimokado K., and Kataoka K. Polyion complex micelles as vectors in gene therapy-pharmacokinetics and in vivo gene transfer. Gene Ther. 9 (2002) 407-414
    • (2002) Gene Ther. , vol.9 , pp. 407-414
    • Harada-Shiba, M.1    Yamauchi, K.2    Harada, A.3    Takamisawa, I.4    Shimokado, K.5    Kataoka, K.6
  • 102
    • 6444243630 scopus 로고    scopus 로고
    • Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing
    • Itaka K., Kanayama N., Nishiyama N., Jang W.D., Yamasaki Y., Nakamura K., Kawaguchi H., and Kataoka K. Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing. J. Am. Chem. Soc. 126 (2004) 13612-13613
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 13612-13613
    • Itaka, K.1    Kanayama, N.2    Nishiyama, N.3    Jang, W.D.4    Yamasaki, Y.5    Nakamura, K.6    Kawaguchi, H.7    Kataoka, K.8
  • 103
    • 31544474910 scopus 로고    scopus 로고
    • RNAi silencing of exogenous and endogenous reporter genes using a macrocyclic octaamine as a "compact" siRNA carrier. Studies on the nonsilenced residual activity
    • Matsui K., Horiuchi S., Sando S., Sera T., and Aoyama Y. RNAi silencing of exogenous and endogenous reporter genes using a macrocyclic octaamine as a "compact" siRNA carrier. Studies on the nonsilenced residual activity. Bioconjug. Chem. 17 (2006) 132-138
    • (2006) Bioconjug. Chem. , vol.17 , pp. 132-138
    • Matsui, K.1    Horiuchi, S.2    Sando, S.3    Sera, T.4    Aoyama, Y.5
  • 104
    • 0000359889 scopus 로고
    • Specific antiviral activity of poly(l-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site
    • Lemaitre M., Bayard B., and Lebleu B. Specific antiviral activity of poly(l-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 648-652
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 648-652
    • Lemaitre, M.1    Bayard, B.2    Lebleu, B.3
  • 105
    • 0028239908 scopus 로고
    • The third helix of the Antennapedia homeodomain translocates through biological membranes
    • Derossi D., Joliot A.H., Chassaing G., and Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 269 (1994) 10444-10450
    • (1994) J. Biol. Chem. , vol.269 , pp. 10444-10450
    • Derossi, D.1    Joliot, A.H.2    Chassaing, G.3    Prochiantz, A.4
  • 106
    • 0036792527 scopus 로고    scopus 로고
    • Peptide-mediated cell delivery: application in protein target validation
    • Lindsay M.A. Peptide-mediated cell delivery: application in protein target validation. Curr. Opin. Pharmacol. 2 (2002) 587-594
    • (2002) Curr. Opin. Pharmacol. , vol.2 , pp. 587-594
    • Lindsay, M.A.1
  • 108
    • 34548840356 scopus 로고    scopus 로고
    • O. Mykhaylyk, D. Vlaskou, N. Tresilwised, P. Pithayanukul, W. Möller, C. Plank, Magnetic nanoparticle formulations for DNA and siRNA delivery, J. Magn. Magn. Mater. (in press).
  • 109
    • 24744437125 scopus 로고    scopus 로고
    • Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing
    • Kam N.W., Liu Z., and Dai H. Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing. J. Am. Chem. Soc. 127 (2005) 12492-12493
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 12492-12493
    • Kam, N.W.1    Liu, Z.2    Dai, H.3


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