메뉴 건너뛰기




Volumn 54, Issue , 2005, Pages 115-142

In Vivo Application of RNA Interference: From Functional Genomics to Therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA;

EID: 25144498128     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2660(05)54006-9     Document Type: Review
Times cited : (157)

References (64)
  • 1
    • 15044354554 scopus 로고    scopus 로고
    • RNAi-induced gene silencing by local electroporation in targeting brain region
    • Akaneya Y., Jiang B., and Tsumoto T. RNAi-induced gene silencing by local electroporation in targeting brain region. J. Neurophysiol. 93 (2005) 594-602
    • (2005) J. Neurophysiol. , vol.93 , pp. 594-602
    • Akaneya, Y.1    Jiang, B.2    Tsumoto, T.3
  • 2
    • 11244328982 scopus 로고    scopus 로고
    • RNA interference and the use of small interfering RNA to study gene function in mammalian systems
    • Bantounas I., Phylactou L.A., and Uney J.B. RNA interference and the use of small interfering RNA to study gene function in mammalian systems. J. Mol. Endocrinol. 33 (2004) 545-557
    • (2004) J. Mol. Endocrinol. , vol.33 , pp. 545-557
    • Bantounas, I.1    Phylactou, L.A.2    Uney, J.B.3
  • 3
    • 5444234179 scopus 로고    scopus 로고
    • RNA interference: From model organisms towards therapy for neural and neuromuscular disorders
    • Buckingham S.D., Esmaeili B., Wood M., and Sattelle D.B. RNA interference: From model organisms towards therapy for neural and neuromuscular disorders. Hum. Mol. Genet. Spec. No 2 (2004) R275-R288
    • (2004) Hum. Mol. Genet. Spec. , vol.No 2
    • Buckingham, S.D.1    Esmaeili, B.2    Wood, M.3    Sattelle, D.B.4
  • 6
    • 3843086047 scopus 로고    scopus 로고
    • Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice
    • Contreras J.L., Vilatoba M., Eckstein C., Bilbao G., Anthony Thompson J., and Eckhoff D.E. Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice. Surgery 136 (2004) 390-400
    • (2004) Surgery , vol.136 , pp. 390-400
    • Contreras, J.L.1    Vilatoba, M.2    Eckstein, C.3    Bilbao, G.4    Anthony Thompson, J.5    Eckhoff, D.E.6
  • 7
    • 1242316299 scopus 로고    scopus 로고
    • Molecular medicine for the brain: Silencing of disease genes with RNA interference
    • Davidson B.L., and Paulson H.L. Molecular medicine for the brain: Silencing of disease genes with RNA interference. Lancet Neurol. 3 3 (2004) 145-149
    • (2004) Lancet Neurol. , vol.3 , Issue.3 , pp. 145-149
    • Davidson, B.L.1    Paulson, H.L.2
  • 9
    • 14844327984 scopus 로고    scopus 로고
    • p27(Kip1) and cyclin D1 are necessary for focal adhesion kinase (FAK) regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain
    • Ding Q., Grammer J.R., Nelson M.A., Guan J.L., Stewart Jr. J.E., and Glodson C.L. p27(Kip1) and cyclin D1 are necessary for focal adhesion kinase (FAK) regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain. J. Biol. Chem. (2004 Nov 19) (2004)
    • (2004) J. Biol. Chem. (2004 Nov 19)
    • Ding, Q.1    Grammer, J.R.2    Nelson, M.A.3    Guan, J.L.4    Stewart Jr., J.E.5    Glodson, C.L.6
  • 11
    • 4644349816 scopus 로고    scopus 로고
    • Liposomes modified with cyclic RGD peptide for tumor targeting
    • Dubey P.K., Mishra V., Jain S., Mahor S., and Vyas S.P. Liposomes modified with cyclic RGD peptide for tumor targeting. J. Drug Target. 12 (2004) 257-264
    • (2004) J. Drug Target. , vol.12 , pp. 257-264
    • Dubey, P.K.1    Mishra, V.2    Jain, S.3    Mahor, S.4    Vyas, S.P.5
  • 12
    • 1542742114 scopus 로고    scopus 로고
    • RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
    • Duxbury M.S., Ito H., Zinner M.J., Ashley S.W., and Whang E.E. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene 23 (2004) 1539-1548
    • (2004) Oncogene , vol.23 , pp. 1539-1548
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 13
    • 0042173218 scopus 로고    scopus 로고
    • SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
    • Filleur S., Courtin A., Ait-Si-Ali S., Guglielmi J., Merle C., Harel-Bellan A., Clezardin P., and Cabon F. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 63 (2003) 3919-3922
    • (2003) Cancer Res. , vol.63 , pp. 3919-3922
    • Filleur, S.1    Courtin, A.2    Ait-Si-Ali, S.3    Guglielmi, J.4    Merle, C.5    Harel-Bellan, A.6    Clezardin, P.7    Cabon, F.8
  • 14
    • 1842734241 scopus 로고    scopus 로고
    • Potential applications of siRNA for pain therapy
    • Ganju P., and Hall J. Potential applications of siRNA for pain therapy. Expert Opin Biol Ther. 4 (2004) 531-542
    • (2004) Expert Opin Biol Ther. , vol.4 , pp. 531-542
    • Ganju, P.1    Hall, J.2
  • 15
    • 2942530436 scopus 로고    scopus 로고
    • Inhibition of influenza virus production in virus-infected mice by RNA interference
    • Ge Q., Filip L., Bai A., Nguyen T., Eisen H.N., and Chen J. Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc. Natl. Acad. Sci. USA 101 (2004) 8676-8681
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8676-8681
    • Ge, Q.1    Filip, L.2    Bai, A.3    Nguyen, T.4    Eisen, H.N.5    Chen, J.6
  • 18
  • 23
    • 2942548218 scopus 로고    scopus 로고
    • Block copolymer-coated calcium phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery
    • Kakizawa Y., Furukawa S., and Kataoka K. Block copolymer-coated calcium phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery. J. Control Release 97 (2004) 345-356
    • (2004) J. Control Release , vol.97 , pp. 345-356
    • Kakizawa, Y.1    Furukawa, S.2    Kataoka, K.3
  • 24
    • 2442705429 scopus 로고    scopus 로고
    • Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
    • Kariko K., Bhuyan P., Capodici J., and Weissman D. Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3. J. Immunol. 172 (2004) 6545-6549
    • (2004) J. Immunol. , vol.172 , pp. 6545-6549
    • Kariko, K.1    Bhuyan, P.2    Capodici, J.3    Weissman, D.4
  • 25
    • 4644293047 scopus 로고    scopus 로고
    • Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: In vitro and in vivo studies
    • Khan A., Benboubetra M., Sayyed P.Z., Ng K.W., Fox S., Beck G., Benter I.F., and Akhtar S. Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: In vitro and in vivo studies. J. Drug Target. 12 (2004) 393-404
    • (2004) J. Drug Target. , vol.12 , pp. 393-404
    • Khan, A.1    Benboubetra, M.2    Sayyed, P.Z.3    Ng, K.W.4    Fox, S.5    Beck, G.6    Benter, I.F.7    Akhtar, S.8
  • 26
    • 9644275599 scopus 로고    scopus 로고
    • Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis
    • Kim B., Tang Q., Biswas P.S., Xu J., Schiffelers R.M., Xie F.Y., Ansari A.M., Scaria P.V., Woodle M.C., Lu P., and Rouse B.T. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis. Am. J. Pathol. 165 (2004) 2177-2185
    • (2004) Am. J. Pathol. , vol.165 , pp. 2177-2185
    • Kim, B.1    Tang, Q.2    Biswas, P.S.3    Xu, J.4    Schiffelers, R.M.5    Xie, F.Y.6    Ansari, A.M.7    Scaria, P.V.8    Woodle, M.C.9    Lu, P.10    Rouse, B.T.11
  • 29
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis D.L., Hagstrom J.E., Loomis A.G., Wolff J.A., and Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nature Genet. 32 (2002) 107-108
    • (2002) Nature Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 31
    • 33645921527 scopus 로고    scopus 로고
    • Tumor inhibition by RNAi-mediated VEGF and VEGFR2 down regulation in xenograft models
    • Lu P.Y., Xie F.Y., and Woodle M.C. Tumor inhibition by RNAi-mediated VEGF and VEGFR2 down regulation in xenograft models. Cancer Gene Ther. 10 Suppl. 1 (2002) 011
    • (2002) Cancer Gene Ther. , vol.10 , Issue.SUPPL. 1 , pp. 011
    • Lu, P.Y.1    Xie, F.Y.2    Woodle, M.C.3
  • 32
    • 0041452805 scopus 로고    scopus 로고
    • From correlation to causation to control: Utilizing preclinical disease models to improve cancer target discovery
    • Lu P.Y., Xie F.Y., Scaria P., and Woodle M.C. From correlation to causation to control: Utilizing preclinical disease models to improve cancer target discovery. Preclinica 1 (2003) 31-42
    • (2003) Preclinica , vol.1 , pp. 31-42
    • Lu, P.Y.1    Xie, F.Y.2    Scaria, P.3    Woodle, M.C.4
  • 33
    • 0141613693 scopus 로고    scopus 로고
    • siRNA-mediated antitumorgenesis for drug target validation and therapeutics
    • Lu P.Y., Xie F.Y., and Woodle M.C. siRNA-mediated antitumorgenesis for drug target validation and therapeutics. Curr. Opin. Mol. Ther. 5 (2003) 225-234
    • (2003) Curr. Opin. Mol. Ther. , vol.5 , pp. 225-234
    • Lu, P.Y.1    Xie, F.Y.2    Woodle, M.C.3
  • 34
    • 14844320045 scopus 로고    scopus 로고
    • Modulation of angiogenesis with siRNA inhibitors for novel therapeutics
    • Lu P.Y., Xie F.Y., and Woodle M.C. Modulation of angiogenesis with siRNA inhibitors for novel therapeutics. Trends Mol. Med. 11 (2005) 104-113
    • (2005) Trends Mol. Med. , vol.11 , pp. 104-113
    • Lu, P.Y.1    Xie, F.Y.2    Woodle, M.C.3
  • 35
    • 4644302416 scopus 로고    scopus 로고
    • Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice
    • Massaro D., Massaro G.D., and Clerch L.B. Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice. Am. J. Physiol. Lung Cell Mol. Physiol. 287 (2004) L1066-L1070
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.287
    • Massaro, D.1    Massaro, G.D.2    Clerch, L.B.3
  • 37
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus M.T., and Sharp P.A. Gene silencing in mammals by small interfering RNAs. Nature Med. 3 (2002) 737-747
    • (2002) Nature Med. , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 39
    • 0141990620 scopus 로고    scopus 로고
    • Tumor-targeted gene therapy: Strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes
    • Ogris M., Walker G., Blessing T., Kircheis R., Wolschek M., and Wagner E. Tumor-targeted gene therapy: Strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes. J. Controll. Release 91 (2003) 173-181
    • (2003) J. Controll. Release , vol.91 , pp. 173-181
    • Ogris, M.1    Walker, G.2    Blessing, T.3    Kircheis, R.4    Wolschek, M.5    Wagner, E.6
  • 40
    • 3142731321 scopus 로고    scopus 로고
    • Intravenous, non-viral RNAi gene therapy of brain cancer
    • Pardridge W.M. Intravenous, non-viral RNAi gene therapy of brain cancer. Expert Opin. Biol. Ther. 4 (2004) 1103-1113
    • (2004) Expert Opin. Biol. Ther. , vol.4 , pp. 1103-1113
    • Pardridge, W.M.1
  • 42
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • Reich S.J., Fosnot J., Kuroki A., Tang W., Yang X., Maguire A.M., Bennett J., and Tolentino M.J. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol. Vision 9 (2003) 210-216
    • (2003) Mol. Vision , vol.9 , pp. 210-216
    • Reich, S.J.1    Fosnot, J.2    Kuroki, A.3    Tang, W.4    Yang, X.5    Maguire, A.M.6    Bennett, J.7    Tolentino, M.J.8
  • 43
    • 0035813464 scopus 로고    scopus 로고
    • Synthesis of galactosyl compounds for targeted gene delivery
    • Ren T., Zhang G., and Liu D. Synthesis of galactosyl compounds for targeted gene delivery. Bioorg. Med. Chem. 9 (2001) 2969-2978
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 2969-2978
    • Ren, T.1    Zhang, G.2    Liu, D.3
  • 44
    • 1842607714 scopus 로고    scopus 로고
    • Towards in vivo application of RNA interference: New toys, old problems
    • Rutz S., and Scheffold A. Towards in vivo application of RNA interference: New toys, old problems. Arthritis Res. Ther. 6 (2004) 78-85
    • (2004) Arthritis Res. Ther. , vol.6 , pp. 78-85
    • Rutz, S.1    Scheffold, A.2
  • 45
    • 1642498310 scopus 로고    scopus 로고
    • Pharmaceutical prospects for RNA interference
    • Schiffelers R.M., Woodle M.C., and Scaria P. Pharmaceutical prospects for RNA interference. Pharm. Res. 21 (2004) 1-7
    • (2004) Pharm. Res. , vol.21 , pp. 1-7
    • Schiffelers, R.M.1    Woodle, M.C.2    Scaria, P.3
  • 47
    • 17244378648 scopus 로고    scopus 로고
    • Effects of treatment with small interferring RNA on joint inflammation in mice with collagen-induced arthritis
    • Schiffelers R.M., Xu J., Storm G., Woodle M.C., and Scaria P.V. Effects of treatment with small interferring RNA on joint inflammation in mice with collagen-induced arthritis. Arthritis & Rheumatism 52 (2005) 1314-1318
    • (2005) Arthritis & Rheumatism , vol.52 , pp. 1314-1318
    • Schiffelers, R.M.1    Xu, J.2    Storm, G.3    Woodle, M.C.4    Scaria, P.V.5
  • 49
    • 0142091755 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus protein expression by RNA interference
    • Sen A., Steele R., Ghosh A.K., Basu A., Ray R., and Ray R.B. Inhibition of hepatitis C virus protein expression by RNA interference. Virus Res. 96 (2003) 27-35
    • (2003) Virus Res. , vol.96 , pp. 27-35
    • Sen, A.1    Steele, R.2    Ghosh, A.K.3    Basu, A.4    Ray, R.5    Ray, R.B.6
  • 50
    • 8444249644 scopus 로고    scopus 로고
    • Attenuation of alpha (2A)-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood
    • Shishkina G.T., Kalinina T.S., and Dygalo N.N. Attenuation of alpha (2A)-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood. Neuroscience 129 (2004) 521-528
    • (2004) Neuroscience , vol.129 , pp. 521-528
    • Shishkina, G.T.1    Kalinina, T.S.2    Dygalo, N.N.3
  • 53
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • 327
    • Sorensen D.R., Leirdal M., and Sioud M. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 4 (2003) 761-766 327
    • (2003) J. Mol. Biol. , vol.4 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 55
    • 6344291687 scopus 로고    scopus 로고
    • Lipidic carriers of siRNA: Differences in the formulation, cellular uptake, and delivery with plasmid DNA
    • Spagnou S., Miller A.D., and Keller M. Lipidic carriers of siRNA: Differences in the formulation, cellular uptake, and delivery with plasmid DNA. Biochemistry 43 (2004) 13348-13356
    • (2004) Biochemistry , vol.43 , pp. 13348-13356
    • Spagnou, S.1    Miller, A.D.2    Keller, M.3
  • 56
    • 10344228801 scopus 로고    scopus 로고
    • Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using non-viral RNA interference
    • Thakker D.R., Natt F., Husken D., Maier R., Muller M., van der Putten H., Hoyer D., and Cryan J.F. Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using non-viral RNA interference. Proc. Natl. Acad. Sci. USA 101 (2004) 17270-17275
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 17270-17275
    • Thakker, D.R.1    Natt, F.2    Husken, D.3    Maier, R.4    Muller, M.5    van der Putten, H.6    Hoyer, D.7    Cryan, J.F.8
  • 57
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • Tiscornia G., Singer O., Ikawa M., and Verma I.M. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA 100 (2003) 1844-1848
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 58
    • 2942620143 scopus 로고    scopus 로고
    • Protection against lethal influenza virus challenge by RNA interference in vivo
    • Tompkins S.M., Lo C.Y., Tumpey T.M., and Epstein S.L. Protection against lethal influenza virus challenge by RNA interference in vivo. Proc. Natl. Acad. Sci. USA 101 (2004) 8682-8686
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8682-8686
    • Tompkins, S.M.1    Lo, C.Y.2    Tumpey, T.M.3    Epstein, S.L.4
  • 59
    • 14044252938 scopus 로고    scopus 로고
    • Toward synthetic viruses: Endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo
    • Walker G.F., Fella C., Pelisek J., Fahrmeir J., Boeckle S., Ogris M., and Wagner E. Toward synthetic viruses: Endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. Mol. Ther. 11 3 (2005) 418-425
    • (2005) Mol. Ther. , vol.11 , Issue.3 , pp. 418-425
    • Walker, G.F.1    Fella, C.2    Pelisek, J.3    Fahrmeir, J.4    Boeckle, S.5    Ogris, M.6    Wagner, E.7
  • 62
    • 14844309091 scopus 로고    scopus 로고
    • Delivering sirna to animal disease models for validation of novel drug targets in vivo
    • Xie F.Y., Liu Y., Xu J., Tang Q.Q., Scaria P.V., Zhou Q., Woodle M.C., and Lu P.Y. Delivering sirna to animal disease models for validation of novel drug targets in vivo. PharmaGenomics July/August (2004) 28-38
    • (2004) PharmaGenomics , vol.July-August , pp. 28-38
    • Xie, F.Y.1    Liu, Y.2    Xu, J.3    Tang, Q.Q.4    Scaria, P.V.5    Zhou, Q.6    Woodle, M.C.7    Lu, P.Y.8
  • 64
    • 1642291631 scopus 로고    scopus 로고
    • Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis
    • Zhang X., Shan P., Jiang D., Noble P.W., Abraham N.G., Kappas A., and Lee P.J. Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. J. Biol. Chem. 279 (2003) 10677-10684
    • (2003) J. Biol. Chem. , vol.279 , pp. 10677-10684
    • Zhang, X.1    Shan, P.2    Jiang, D.3    Noble, P.W.4    Abraham, N.G.5    Kappas, A.6    Lee, P.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.