GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allele-specific small interfering RNA (siRNA)

Endocrinology

Volumn 145, Issue 6, 2004, Pages 2988-2996

  Ryther, Robin C C ^a   Flynt, Alex S ^a   Harris, Bryan D ^a   Phillips III, John A ^b   Patton, James G ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; ISOPROTEIN; NUCLEOTIDE; SMALL INTERFERING RNA;

ALLELE; ARTICLE; DNA FLANKING REGION; DNA POLYMORPHISM; EXON; GENE CONTROL; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GROWTH HORMONE DEFICIENCY; INTRON; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SPLICING;

ALLELES; ANIMALS; BASE SEQUENCE; CELL LINE; DNA, RECOMBINANT; ENHANCER ELEMENTS (GENETICS); EXONS; GENE DELETION; GENES, DOMINANT; HUMAN GROWTH HORMONE; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN ISOFORMS; RNA, SMALL INTERFERING;

EID: 2542427517     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-1724     Document Type: Article

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