Harnessing in vivo siRNA delivery for drug discovery and therapeutic development

Drug Discovery Today

Volumn 11, Issue 1-2, 2006, Pages 67-73

  Xie, Frank Y ^a   Woodle, Martin C ^a   Lu, Patrick Y ^a  

^a Intradigm Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ADENOVIRUS VECTOR; ALPHA 2 ADRENERGIC RECEPTOR; ANTISENSE OLIGODEOXYNUCLEOTIDE; APOLIPOPROTEIN B; APTAMER; ARGINYLGLYCYLASPARTIC ACID; ATELOCOLLAGEN; CALFACTANT; CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; CARDIOLIPIN; CASPASE 3; CASPASE 8; CYCLOOXYGENASE 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEME OXYGENASE 1; INTERFERON; IODINATED POPPYSEED OIL; LENTIVIRUS VECTOR; LIPID; NANOPARTICLE; PLASMID VECTOR; POLYETHYLENEIMINE; POLYMER; RETROVIRUS VECTOR; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VANOXERINE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANTIANGIOGENIC ACTIVITY; ARTHRITIS; ASTHMA; CANCER INHIBITION; CENTRAL NERVOUS SYSTEM DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG LIVER LEVEL; DRUG TARGETING; DRUG UPTAKE; ELECTROPORATION; EYE DISEASE; FUNCTIONAL GENOMICS; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; HEPATITIS B; IN VIVO STUDY; INFLUENZA VIRUS; INFLUENZA VIRUS A; INTERFERON PRODUCTION; KNOCKOUT MOUSE; LIVER METASTASIS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARKINSON DISEASE; PNEUMONIA; PROTEIN EXPRESSION; PROTEIN MOTIF; REPORTER GENE; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION; RETINOPATHY; REVIEW; RHEUMATOID ARTHRITIS; RNA INTERFERENCE; RNA SEQUENCE; RNA STRUCTURE; SEVERE ACUTE RESPIRATORY SYNDROME; VIRAL GENE DELIVERY SYSTEM; VIRUS INHIBITION; VIRUS KERATITIS; XENOGRAFT;

ANIMALS; DRUG ADMINISTRATION ROUTES; DRUG DELIVERY SYSTEMS; DRUG DESIGN; GENE TARGETING; HUMANS; RNA, SMALL INTERFERING;

EID: 32444445649     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(05)03668-8     Document Type: Review

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