-
1
-
-
0024450510
-
Endotoxin-induced shock in the rat: A role for C5a
-
Smedegard, G., L. X. Cui, and T. E. Hugli. 1989. Endotoxin-induced shock in the rat: a role for C5a. Am. J. Pathol. 135: 489-497.
-
(1989)
Am. J. Pathol.
, vol.135
, pp. 489-497
-
-
Smedegard, G.1
Cui, L.X.2
Hugli, T.E.3
-
2
-
-
0022453148
-
Effects of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates
-
Stevens, J. H., P. O'Hanley, J. M. Shapiro, F.G. Mihm, P. S. Satoh, J. A. Collins. and T. A. Raffin. 1986. Effects of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates. J. Clin. Invest. 77: 1812-1816.
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 1812-1816
-
-
Stevens, J.H.1
O'Hanley, P.2
Shapiro, J.M.3
Mihm, F.G.4
Satoh, P.S.5
Collins, J.A.6
Raffin, T.A.7
-
3
-
-
0029114993
-
Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease
-
Wang, Y., S. A. Rollins, J. A. Madri, and L. A. Matis. 1995. Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease. Proc. Natl. Acad. Sci. USA 92: 8955-8959.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8955-8959
-
-
Wang, Y.1
Rollins, S.A.2
Madri, J.A.3
Matis, L.A.4
-
4
-
-
0024598582
-
Complement levels in septic primates treated with anti-C5a antibodies
-
Hangen, D. H., J. H. Stevens, P. S. Satoh, E. W. Hall, P. T. O'Hanley, and T. A. Raffin. 1989. Complement levels in septic primates treated with anti-C5a antibodies. J. Surg. Res. 46: 195-197.
-
(1989)
J. Surg. Res.
, vol.46
, pp. 195-197
-
-
Hangen, D.H.1
Stevens, J.H.2
Satoh, P.S.3
Hall, E.W.4
O'Hanley, P.T.5
Raffin, T.A.6
-
5
-
-
0023772348
-
C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro: Comparison with secretion of interleukin 1β and interleukin 1α
-
Okusawa, S., K. B. Yancey, J. W. van der Meer, S. Endres, G. Lonnemann, K. Hefter, M. M. Frank, J. F. Burke, C. A. Dinarello, and J. A. Gelfand. 1988. C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro: comparison with secretion of interleukin 1β and interleukin 1α. J. Exp. Med. 168: 443-448.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 443-448
-
-
Okusawa, S.1
Yancey, K.B.2
Van Der Meer, J.W.3
Endres, S.4
Lonnemann, G.5
Hefter, K.6
Frank, M.M.7
Burke, J.F.8
Dinarello, C.A.9
Gelfand, J.A.10
-
6
-
-
0024583377
-
Absence of induction of IL-1 production in human monocytes by complement fragments
-
Arend, W. P., R. J. Massoni, M. A. Niemann, and P. C. Giclas. 1989. Absence of induction of IL-1 production in human monocytes by complement fragments. J. Immunol. 142: 173-178.
-
(1989)
J. Immunol.
, vol.142
, pp. 173-178
-
-
Arend, W.P.1
Massoni, R.J.2
Niemann, M.A.3
Giclas, P.C.4
-
7
-
-
0023242020
-
C5a induction of human interleukin 1
-
Okusawa, S., C. A. Dinarello, K. B. Yancey, S. Endres, T. J. Lawley, M. M. Frank, J. F. Burke, and J. A. Gelfand. 1987. C5a induction of human interleukin 1. J. Immunol. 139: 2635-2640.
-
(1987)
J. Immunol.
, vol.139
, pp. 2635-2640
-
-
Okusawa, S.1
Dinarello, C.A.2
Yancey, K.B.3
Endres, S.4
Lawley, T.J.5
Frank, M.M.6
Burke, J.F.7
Gelfand, J.A.8
-
8
-
-
0025092009
-
Recombinant C5a enhances interleukin 1 and tumor necrosis factor release by lipopolysaccharide-stimulated monocytes and macrophages
-
Cavaillon, J.-M., C. Fitting, and N. Haeffner-Cavaillon. 1990. Recombinant C5a enhances interleukin 1 and tumor necrosis factor release by lipopolysaccharide-stimulated monocytes and macrophages. Eur. J. Immunol. 20: 253-257.
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 253-257
-
-
Cavaillon, J.-M.1
Fitting, C.2
Haeffner-Cavaillon, N.3
-
9
-
-
15444353437
-
Novel C5a antagonists regulate neutrophil functions in vitro and in vivo
-
Pellas, T. C., W. Boyar, J. van Oostrum, J. Wasvary, L. R. Fryer, G. Pastor, M. Sills, A. Braunwalder, D. R. Yarwood, R. Kramer, et al. 1998. Novel C5a antagonists regulate neutrophil functions in vitro and in vivo. J. Immunol. 160: 5616-5621.
-
(1998)
J. Immunol.
, vol.160
, pp. 5616-5621
-
-
Pellas, T.C.1
Boyar, W.2
Van Oostrum, J.3
Wasvary, J.4
Fryer, L.R.5
Pastor, G.6
Sills, M.7
Braunwalder, A.8
Yarwood, D.R.9
Kramer, R.10
-
10
-
-
0031982250
-
Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis
-
Mohr, M., U. Hopken, M. Oppermann, C. Mathes, K. Goldmann, S. Siever, O. Gotze, and H. Burchardi. 1998. Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis. Eur. J. Clin. Invest. 28: 227-234.
-
(1998)
Eur. J. Clin. Invest.
, vol.28
, pp. 227-234
-
-
Mohr, M.1
Hopken, U.2
Oppermann, M.3
Mathes, C.4
Goldmann, K.5
Siever, S.6
Gotze, O.7
Burchardi, H.8
-
11
-
-
0033029306
-
Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat
-
Short, A., A. K. Wong, A. M. Finch, G. Haaima, I. A. Shiels, D. P. Fairlie, and S. M. Taylor. 1999. Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat. Br. J. Pharmacol. 126: 551-554.
-
(1999)
Br. J. Pharmacol.
, vol.126
, pp. 551-554
-
-
Short, A.1
Wong, A.K.2
Finch, A.M.3
Haaima, G.4
Shiels, I.A.5
Fairlie, D.P.6
Taylor, S.M.7
-
12
-
-
0033052453
-
Protective effects of C5a blockade in sepsis
-
Czermak, B. J., V. Sarma, C. L. Pierson, R. L. Warner, M. Huber-Lang, N. M. Bless, H. Schmal, H. P. Friedl, and P. A. Ward. 1999. Protective effects of C5a blockade in sepsis. Nat. Med. 5: 788-792.
-
(1999)
Nat. Med.
, vol.5
, pp. 788-792
-
-
Czermak, B.J.1
Sarma, V.2
Pierson, C.L.3
Warner, R.L.4
Huber-Lang, M.5
Bless, N.M.6
Schmal, H.7
Friedl, H.P.8
Ward, P.A.9
-
13
-
-
0035863922
-
Role of C5a in multiorgan failure during sepsis
-
Huber-Lang, M., V. J. Sarma, K. T. Lu, S. R. McGuire, V. A. Padgaonkar, R. F. Guo, E. M. Younkin, R. G. Kunkel, J. Ding, R. Erickson, et al. 2001. Role of C5a in multiorgan failure during sepsis. J. Immunol. 166: 1193-1199.
-
(2001)
J. Immunol.
, vol.166
, pp. 1193-1199
-
-
Huber-Lang, M.1
Sarma, V.J.2
Lu, K.T.3
McGuire, S.R.4
Padgaonkar, V.A.5
Guo, R.F.6
Younkin, E.M.7
Kunkel, R.G.8
Ding, J.9
Erickson, R.10
-
14
-
-
0033565711
-
Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury
-
Heller, T., M. Hennecke, U. Baumann, J. E. Gessner, A. M. zu Vilsendorf, M. Baensch, F. Boulay, F. Kola, A. Klos, W. Bautsch, and J. Kohl. 1999. Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury. J. Immunol. 163: 985-994.
-
(1999)
J. Immunol.
, vol.163
, pp. 985-994
-
-
Heller, T.1
Hennecke, M.2
Baumann, U.3
Gessner, J.E.4
Zu Vilsendorf, A.M.5
Baensch, M.6
Boulay, F.7
Kola, F.8
Klos, A.9
Bautsch, W.10
Kohl, J.11
-
15
-
-
0032572818
-
Small molecular probes for the G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a
-
Wong, A. K., A. M. Finch, G. K. Pierens, D. J. Craik, S. M. Taylor, and P. Fairlie, 1998. Small molecular probes for the G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a. J. Med. Chem. 41: 3417-3425.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 3417-3425
-
-
Wong, A.K.1
Finch, A.M.2
Pierens, G.K.3
Craik, D.J.4
Taylor, S.M.5
Fairlie, P.6
-
16
-
-
0033519733
-
Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a
-
Finch, A. M., A. K. Wong, N. J. Paczkowski, S. K. Wadi, D. J. Craik, D. P. Fairlie, and S. M. Taylor. 1999. Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. J. Med. Chem. 42: 1965-1974.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 1965-1974
-
-
Finch, A.M.1
Wong, A.K.2
Paczkowski, N.J.3
Wadi, S.K.4
Craik, D.J.5
Fairlie, D.P.6
Taylor, S.M.7
-
17
-
-
0027994349
-
The sphingomyelin cycle and the second messenger functions of ceramide
-
Hannun, Y. A. 1994. The sphingomyelin cycle and the second messenger functions of ceramide. J. Biol. Chem. 269: 3125-3128.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3125-3128
-
-
Hannun, Y.A.1
-
18
-
-
0028333052
-
Tumor necrosis factor receptor-mediated signaling pathways
-
Heller, R. A., and M. Krönke. 1994. Tumor necrosis factor receptor-mediated signaling pathways. J. Cell Biol. 126: 5-9.
-
(1994)
J. Cell Biol.
, vol.126
, pp. 5-9
-
-
Heller, R.A.1
Krönke, M.2
-
19
-
-
0028297068
-
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
-
Kolesnik, R., and D. W. Golde. 1994. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77: 325-328.
-
(1994)
Cell
, vol.77
, pp. 325-328
-
-
Kolesnik, R.1
Golde, D.W.2
-
20
-
-
0029027837
-
Sphingolipid metabolites: Members of a new class of lipid second messengers
-
Spiegel, S., and S. Milstien. 1995. Sphingolipid metabolites: members of a new class of lipid second messengers. J. Membr. Biol. 146: 225-237.
-
(1995)
J. Membr. Biol.
, vol.146
, pp. 225-237
-
-
Spiegel, S.1
Milstien, S.2
-
22
-
-
0027371722
-
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Olivera, A., and S. Spiegel. 1993. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365: 557-560.
-
(1993)
Nature
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
23
-
-
0029027589
-
Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: Spatial and temporal modulation of PDGF chemotactic signal transduction
-
Bornfeldt, K. E., L. M. Graves, E. W. Raines, Y. Igarashi, G. Wayman, S. Yamamura, Y. Yatomi, J. S. Sidhu, E. G. Krebs, S. Hakomori, and R. Ross. 1995. Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. J. Cell Biol. 130: 193-206.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 193-206
-
-
Bornfeldt, K.E.1
Graves, L.M.2
Raines, E.W.3
Igarashi, Y.4
Wayman, G.5
Yamamura, S.6
Yatomi, Y.7
Sidhu, J.S.8
Krebs, E.G.9
Hakomori, S.10
Ross, R.11
-
24
-
-
0029996127
-
Calcium mobilization via sphingosine kinase in signalling by the FcεRI antigen receptor
-
Choi, O. H., J. H., Kim, and J. P. Kinet. 1996. Calcium mobilization via sphingosine kinase in signalling by the FcεRI antigen receptor. Nature 18: 634-636.
-
(1996)
Nature
, vol.18
, pp. 634-636
-
-
Choi, O.H.1
Kim, J.H.2
Kinet, J.P.3
-
25
-
-
0037052338
-
2+ signals triggered by different phospholipid pathways in antigen stimulation of human mast cells
-
2+ signals triggered by different phospholipid pathways in antigen stimulation of human mast cells. J. Biol. Chem. 277: 17255-17262.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17255-17262
-
-
Melendez, A.J.1
Khaw, A.K.2
-
26
-
-
0032540010
-
FcγRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking
-
Melendez, A., R. A. Floto, D. J. Gillooly, M. M. Harnett, and J. M. Allen. 1998. FcγRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. J. Biol. Chem. 273: 9393-9402.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9393-9402
-
-
Melendez, A.1
Floto, R.A.2
Gillooly, D.J.3
Harnett, M.M.4
Allen, J.M.5
-
27
-
-
0033548157
-
Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase
-
Alemany, R., D. M. zu Henringdorf, C. J. van Koppen, and K. H. Jacobs. 1999. Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. J. Biol. Chem. 274: 3994-3999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3994-3999
-
-
Alemany, R.1
Zu Henringdorf, D.M.2
Van Koppen, C.J.3
Jacobs, K.H.4
-
28
-
-
7244250149
-
Anaphylatoxin signaling in human neutrophils: A key role for sphingosine kinase
-
Ibrahim, F. B., S. J. Pang, and A. J. Melendez. 2004. Anaphylatoxin signaling in human neutrophils: a key role for sphingosine kinase. J. Biol. Chem. 279: 44802-44811.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44802-44811
-
-
Ibrahim, F.B.1
Pang, S.J.2
Melendez, A.J.3
-
29
-
-
3242791547
-
2+ signals, enzyme release, cytokine production, and chemotaxis
-
2+ signals, enzyme release, cytokine production, and chemotaxis. J. Immunol. 173: 1596-1603.
-
(2004)
J. Immunol.
, vol.173
, pp. 1596-1603
-
-
Melendez, A.J.1
Ibrahim, F.B.2
-
30
-
-
0034659827
-
A new small molecule C5a receptor antagonist inhibits the reverse-passive Arthus reaction and endotoxic shock in rats
-
Strachan, A. J., T. M. Woodruff, G. Haaima, D. P. Fairlie, and S. M. Taylor. 2000. A new small molecule C5a receptor antagonist inhibits the reverse-passive Arthus reaction and endotoxic shock in rats. J. Immunol. 164: 6560-6565.
-
(2000)
J. Immunol.
, vol.164
, pp. 6560-6565
-
-
Strachan, A.J.1
Woodruff, T.M.2
Haaima, G.3
Fairlie, D.P.4
Taylor, S.M.5
-
31
-
-
0344140225
-
Interleukin-1 induces a shock-like state in rabbits: Synergism with tumor necrosis factor and the effects of cyclooxygenase inhibition
-
Okusawa, S., J. A. Gelfand, T. Ikejima, R. A. Connolly, and C. A. Dinarello. 1988. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effects of cyclooxygenase inhibition. J. Clin. Invest. 81: 1162-1172.
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 1162-1172
-
-
Okusawa, S.1
Gelfand, J.A.2
Ikejima, T.3
Connolly, R.A.4
Dinarello, C.A.5
-
32
-
-
0028340312
-
Neutrophil polarisation in plasma differs to that induced by endogenous chemoattractants with regard to frequency of uropod formation and requirement for divalent cations
-
Harkin, D. G., and L. P. Bignold. 1994. Neutrophil polarisation in plasma differs to that induced by endogenous chemoattractants with regard to frequency of uropod formation and requirement for divalent cations. Cell Biol. Int. 18: 177-187.
-
(1994)
Cell Biol. Int.
, vol.18
, pp. 177-187
-
-
Harkin, D.G.1
Bignold, L.P.2
-
33
-
-
0020530671
-
Motility, cell shape, and locomotion of neutrophil granulocytes
-
Keller, H. 1983. Motility, cell shape, and locomotion of neutrophil granulocytes. Cell Motil. 3: 47-60.
-
(1983)
Cell Motil.
, vol.3
, pp. 47-60
-
-
Keller, H.1
-
34
-
-
1842333302
-
Impaired inflammatory responses in the reverse Arthus reaction through genetic deletion of the C5a receptor
-
Hopken, U. E., B. Lu, N. P. Gerard, and C. Gerard. 1997. Impaired inflammatory responses in the reverse Arthus reaction through genetic deletion of the C5a receptor. J. Exp. Med. 186: 749-756.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 749-756
-
-
Hopken, U.E.1
Lu, B.2
Gerard, N.P.3
Gerard, C.4
-
35
-
-
4344600286
-
C5a initiates the inflammatory cascade in immune complex peritonitis
-
Godau, J., T. Heller, H. Hawlisch, M. Trappe, E. Howells, J. Best, J. Zwirner, J. S. Verbeek, P. M. Hogarth, C. Gerard, et al. 2004. C5a initiates the inflammatory cascade in immune complex peritonitis. J. Immunol. 173: 3437-3445.
-
(2004)
J. Immunol.
, vol.173
, pp. 3437-3445
-
-
Godau, J.1
Heller, T.2
Hawlisch, H.3
Trappe, M.4
Howells, E.5
Best, J.6
Zwirner, J.7
Verbeek, J.S.8
Hogarth, P.M.9
Gerard, C.10
-
36
-
-
0032865060
-
Increased IL-12 release by monocytes in nephritic patients
-
Matsumoto, K., and K. Kanmatsuse. 1999. Increased IL-12 release by monocytes in nephritic patients. Clin. Exp. Immunol. 117: 361-367.
-
(1999)
Clin. Exp. Immunol.
, vol.117
, pp. 361-367
-
-
Matsumoto, K.1
Kanmatsuse, K.2
-
37
-
-
0032936549
-
On the edge: The physiological and pathophysiological role of chemokines during inflammatory and immunological responses
-
DeVries, M. E., L. Ran, and D. J. Kelvin. 1999. On the edge: the physiological and pathophysiological role of chemokines during inflammatory and immunological responses. Semin. Immunol. 11: 95-104.
-
(1999)
Semin. Immunol.
, vol.11
, pp. 95-104
-
-
DeVries, M.E.1
Ran, L.2
Kelvin, D.J.3
-
38
-
-
0032717103
-
Differential roles of IL-1 and TNF-α on graft-versus-host disease and graft versus leukemia
-
Hill, G. R., T. Teshima, A. Gerbitz, L. Pan, K. R. Cooke, Y. S. Brinson, J. M. Crawford, and J. L. Ferrara. 1999. Differential roles of IL-1 and TNF-α on graft-versus-host disease and graft versus leukemia. J. Clin. Invest. 104: 459-467.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 459-467
-
-
Hill, G.R.1
Teshima, T.2
Gerbitz, A.3
Pan, L.4
Cooke, K.R.5
Brinson, Y.S.6
Crawford, J.M.7
Ferrara, J.L.8
-
39
-
-
0031667722
-
Differing patterns of P-selectin expression in lung injury
-
Bless, N. M., S. J. Tojo, H. Kawarai, Y. Natsume, A. B. Lentsch, V. A. Padgaonkar, B.J. Czermak, H. Schmal, H. P. Friedl, and P. A. Ward. 1998. Differing patterns of P-selectin expression in lung injury. Am. J. Pathol. 153: 1113-1122.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1113-1122
-
-
Bless, N.M.1
Tojo, S.J.2
Kawarai, H.3
Natsume, Y.4
Lentsch, A.B.5
Padgaonkar, V.A.6
Czermak, B.J.7
Schmal, H.8
Friedl, H.P.9
Ward, P.A.10
-
40
-
-
0033556365
-
A comparison of C3a- and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo
-
DiScipio, R. G., P. J. Daffern, M. A. Jagels, D. H. Broide, and P. Sriramarao. 1999. A comparison of C3a- and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo. J. Immunol. 162: 1127-1136.
-
(1999)
J. Immunol.
, vol.162
, pp. 1127-1136
-
-
DiScipio, R.G.1
Daffern, P.J.2
Jagels, M.A.3
Broide, D.H.4
Sriramarao, P.5
|