Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I

Molecular Therapy

Volumn 15, Issue 6, 2007, Pages 1145-1152

  Kim, Soo In ^a   Shin, Duckhyang ^a   Choi, Tae Hyun ^b   Lee, Jong Chan ^b   Cheon, Gi Jeong ^b   Kim, Ki Yong ^c   Park, Mahnhoon ^a   Kim, Meehyein ^a  

^a Mogam Biotechnology Research Institute   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Green Cross Company   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; APOLIPOPROTEIN A1; CHOLESTEROL; LIPOPLEX; LIPOSOME; LUCIFERASE; NANOPARTICLE; SMALL INTERFERING RNA; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; BIOLUMINESCENCE; C57BL 6 MOUSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG SPECIFICITY; ENDOCYTOSIS; FEMALE; GENE SILENCING; HEPATITIS; HEPATITIS B VIRUS; IMAGE ANALYSIS; IMAGING SYSTEM; IN VIVO STUDY; LIVER; LIVER CELL CARCINOMA; LOW DRUG DOSE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; NUDE MOUSE; PROTEIN EXPRESSION; RNA INTERFERENCE; SINGLE DRUG DOSE; VIRUS REPLICATION;

ANIMALS; APOLIPOPROTEIN A-I; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FATTY ACIDS, MONOUNSATURATED; FEMALE; GREEN FLUORESCENT PROTEINS; HEPATITIS B VIRUS; HUMANS; LIVER; LUCIFERASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; NANOPARTICLES; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TISSUE DISTRIBUTION;

HEPATITIS B VIRUS;

EID: 34249279852     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300168     Document Type: Article

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