-
1
-
-
0019423856
-
Sequence and organization of the human mitochondrial genome
-
Anderson, S.; Bankier, A.T.; Barrell, B.G.; de Bruijn, M.H.; Coulson, A.R.; Drouin, J.; Eperon, I.C.; Nierlich, D.P.; Roe, B.A.; Sanger, F.; Schreier, P.H.; Smith, A.J.; Staden, R.; Young, I.G. Sequence and organization of the human mitochondrial genome. Nature 1981, 290, 457-65.
-
(1981)
Nature
, vol.290
, pp. 457-465
-
-
Anderson, S.1
Bankier, A.T.2
Barrell, B.G.3
de Bruijn, M.H.4
Coulson, A.R.5
Drouin, J.6
Eperon, I.C.7
Nierlich, D.P.8
Roe, B.A.9
Sanger, F.10
Schreier, P.H.11
Smith, A.J.12
Staden, R.13
Young, I.G.14
-
2
-
-
0032561249
-
New goals for the U.S. Human Genome Project: 1998-2003
-
Collins, F.S.; Patrinos, A.; Jordan, E.; Chakravarti, A.; Gesteland, R.; Walters, L. New goals for the U.S. Human Genome Project: 1998-2003. Science 1998, 282, 682-9.
-
(1998)
Science
, vol.282
, pp. 682-689
-
-
Collins, F.S.1
Patrinos, A.2
Jordan, E.3
Chakravarti, A.4
Gesteland, R.5
Walters, L.6
-
3
-
-
0035895505
-
-
Venter, J.C, Adams, M.D, Myers, E.W, Li, P.W, Mural, R.J, Sutton, G.G, Smith, H.O, Yandell, M, Evans, C.A, Holt, R.A, Gocayne, J.D, Amanatides, P, Ballew, R.M, Huson, D.H, Wortman, J.R, Zhang, Q, Kodira, C.D, Zheng, X.H, Chen, L, Skupski, M, Subramanian, G, Thomas, P.D, Zhang, J, Gabor Miklos, G.L, Nelson, C, Broder, S, Clark, A.G, Nadeau, J, McKusick, V.A, Zinder, N, Levine, A.J, Roberts, R.J, Simon, M, Slayman, C, Hunkapiller, M, Bolanos, R, Delcher, A, Dew, I, Fasulo, D, Flanigan, M, Florea, L, Halpern, A, Hannenhalli, S, Kravitz, S, Levy, S, Mobarry, C, Reinert, K, Remington, K, Abu-Threideh, J, Beasley, E, Biddick, K, Bonazzi, V, Brandon, R, Cargill, M, Chandramouliswaran, I, Charlab, R, Chaturvedi, K, Deng, Z, Di Francesco, V, Dunn, P, Eilbeck, K, Evangelista, C, Gabrielian, A.E, Gan, W, Ge, W, Gong, F, Gu, Z, Guan, P, Heiman, T.J, Higgins, M.E, Ji, R.R, Ke, Z, Ketchum, K.A, Lai, Z, Lei, Y, Li, Z, Li, J.;
-
Venter, J.C.; Adams, M.D.; Myers, E.W.; Li, P.W.; Mural, R.J.; Sutton, G.G.; Smith, H.O.; Yandell, M.; Evans, C.A.; Holt, R.A.; Gocayne, J.D.; Amanatides, P.; Ballew, R.M.; Huson, D.H.; Wortman, J.R.; Zhang, Q.; Kodira, C.D.; Zheng, X.H.; Chen, L.; Skupski, M.; Subramanian, G.; Thomas, P.D.; Zhang, J.; Gabor Miklos, G.L.; Nelson, C.; Broder, S.; Clark, A.G.; Nadeau, J.; McKusick, V.A.; Zinder, N.; Levine, A.J.; Roberts, R.J.; Simon, M.; Slayman, C.; Hunkapiller, M.; Bolanos, R.; Delcher, A.; Dew, I.; Fasulo, D.; Flanigan, M.; Florea, L.; Halpern, A.; Hannenhalli, S.; Kravitz, S.; Levy, S.; Mobarry, C.; Reinert, K.; Remington, K.; Abu-Threideh, J.; Beasley, E.; Biddick, K.; Bonazzi, V.; Brandon, R.; Cargill, M.; Chandramouliswaran, I.; Charlab, R.; Chaturvedi, K.; Deng, Z.; Di Francesco, V.; Dunn, P.; Eilbeck, K.; Evangelista, C.; Gabrielian, A.E.; Gan, W.; Ge, W.; Gong, F.; Gu, Z.; Guan, P.; Heiman, T.J.; Higgins, M.E.; Ji, R.R.; Ke, Z.; Ketchum, K.A.; Lai, Z.; Lei, Y.; Li, Z.; Li, J.; Liang, Y.; Lin, X.; Lu, F.; Merkulov, G.V.; Milshina, N.; Moore, H.M.; Naik, A.K.; Narayan, V.A.; Neelam, B.; Nusskern, D.; Rusch, D.B.; Salzberg, S.; Shao, W.; Shue, B.; Sun, J.; Wang, Z.; Wang, A.; Wang, X.; Wang, J.; Wei, M.; Wides, R.; Xiao, C.; et al. The sequence of the human genome. Science 2001, 291, 1304-51.
-
-
-
-
4
-
-
0037205001
-
Specialized DNA polymerases, cellular survival, and the genesis of mutations
-
Friedberg, E.C.; Wagner, R.; Radman, M. Specialized DNA polymerases, cellular survival, and the genesis of mutations. Science 2002, 296, 1627-30.
-
(2002)
Science
, vol.296
, pp. 1627-1630
-
-
Friedberg, E.C.1
Wagner, R.2
Radman, M.3
-
5
-
-
0015504248
-
Rate of depurination of native deoxyribonucleic acid
-
Lindahl, T.; Nyberg, B. Rate of depurination of native deoxyribonucleic acid. Biochemistry 1972, 11, 3610-8.
-
(1972)
Biochemistry
, vol.11
, pp. 3610-3618
-
-
Lindahl, T.1
Nyberg, B.2
-
6
-
-
0025766848
-
Compilation and alignment of DNA polymerase sequences
-
Ito, J.; Braithwaite, D.K. Compilation and alignment of DNA polymerase sequences. Nucleic Acids Res. 1991, 19, 4045-57
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 4045-4057
-
-
Ito, J.1
Braithwaite, D.K.2
-
7
-
-
17944380943
-
The Y-family of DNA polymerases
-
Ohmori, H.; Friedberg, E.C.; Fuchs, R.P.; Goodman, M.F.; Hanaoka, F.; Hinkle, D.; Kunkel, T.A.; Lawrence, C.W.; Livneh, Z.; Nohmi, T.; Prakash, L.; Prakash, S.; Todo, T.; Walker, G.C.; Wang, Z.; Woodgate, R. The Y-family of DNA polymerases. Mol. Cell 2001, 8, 7-8.
-
(2001)
Mol. Cell
, vol.8
, pp. 7-8
-
-
Ohmori, H.1
Friedberg, E.C.2
Fuchs, R.P.3
Goodman, M.F.4
Hanaoka, F.5
Hinkle, D.6
Kunkel, T.A.7
Lawrence, C.W.8
Livneh, Z.9
Nohmi, T.10
Prakash, L.11
Prakash, S.12
Todo, T.13
Walker, G.C.14
Wang, Z.15
Woodgate, R.16
-
8
-
-
0042894603
-
Enzymatic Synthesis of Deoxyribonucleic Acid. V. Chemical Composition of Enzymatically Synthesized Deoxyribonucleic Acid
-
Lehman, I.R.; Zimmerman, S.B.; Adler, J.; Bessman, M.J.; Simms, E.S.; Kornberg, A. Enzymatic Synthesis of Deoxyribonucleic Acid. V. Chemical Composition of Enzymatically Synthesized Deoxyribonucleic Acid. Proc. Natl. Acad. Sci. USA 1958, 44, 1191-6.
-
(1958)
Proc. Natl. Acad. Sci. USA
, vol.44
, pp. 1191-1196
-
-
Lehman, I.R.1
Zimmerman, S.B.2
Adler, J.3
Bessman, M.J.4
Simms, E.S.5
Kornberg, A.6
-
9
-
-
0036342502
-
Multiple mitochondrial DNA polymerases in Trypanosoma brucei
-
Klingbeil, M.M.; Motyka, S.A.; Englund, P.T. Multiple mitochondrial DNA polymerases in Trypanosoma brucei. Mol Cell 2002, 10, 175-86.
-
(2002)
Mol Cell
, vol.10
, pp. 175-186
-
-
Klingbeil, M.M.1
Motyka, S.A.2
Englund, P.T.3
-
10
-
-
0027231782
-
Structure of DNA polymerase I Klenow fragment bound to duplex DNA
-
Beese, L.S.; Derbyshire, V.; Steitz, T.A. Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Science 1993, 260, 352-5.
-
(1993)
Science
, vol.260
, pp. 352-355
-
-
Beese, L.S.1
Derbyshire, V.2
Steitz, T.A.3
-
11
-
-
0032518398
-
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution
-
Doublie, S.; Tabor, S.; Long, A.M.; Richardson, C.C.; Ellenberger, T. Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution. Nature 1998, 391, 251-8.
-
(1998)
Nature
, vol.391
, pp. 251-258
-
-
Doublie, S.1
Tabor, S.2
Long, A.M.3
Richardson, C.C.4
Ellenberger, T.5
-
12
-
-
0030587492
-
Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma
-
Ropp, P.A.; Copeland, W.C. Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma. Genomics 1996, 36, 449-58.
-
(1996)
Genomics
, vol.36
, pp. 449-458
-
-
Ropp, P.A.1
Copeland, W.C.2
-
13
-
-
0033621374
-
The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance
-
Lim, S.E.; Longley, M.J.; Copeland, W.C. The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. J. Biol. Chem. 1999, 274, 38197-203.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 38197-38203
-
-
Lim, S.E.1
Longley, M.J.2
Copeland, W.C.3
-
14
-
-
46349103594
-
A mitochondrial protein compendium elucidates complex I disease biology
-
Pagliarini, D.J.; Calvo, S.E.; Chang, B.; Sheth, S.A.; Vafai, S.B.; Ong, S.E.; Walford, G.A.; Sugiana, C.; Boneh, A.; Chen, W.K.; Hill, D.E.; Vidal, M.; Evans, J.G.; Thorburn, D.R.; Carr, S.A.; Mootha, V.K. A mitochondrial protein compendium elucidates complex I disease biology. Cell 2008, 134, 112-23.
-
(2008)
Cell
, vol.134
, pp. 112-123
-
-
Pagliarini, D.J.1
Calvo, S.E.2
Chang, B.3
Sheth, S.A.4
Vafai, S.B.5
Ong, S.E.6
Walford, G.A.7
Sugiana, C.8
Boneh, A.9
Chen, W.K.10
Hill, D.E.11
Vidal, M.12
Evans, J.G.13
Thorburn, D.R.14
Carr, S.A.15
Mootha, V.K.16
-
15
-
-
55049124777
-
Long patch base excision repair in mammalian mitochondrial genomes
-
Szczesny, B.; Tann, A.W.; Longley, M.J.; Copeland, W.C.; Mitra, S. Long patch base excision repair in mammalian mitochondrial genomes. J. Biol. Chem. 2008,
-
(2008)
J. Biol. Chem
-
-
Szczesny, B.1
Tann, A.W.2
Longley, M.J.3
Copeland, W.C.4
Mitra, S.5
-
16
-
-
2342578088
-
DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA
-
Stuart, J.A.; Hashiguchi, K.; Wilson, D.M., 3rd; Copeland, W.C.; Souza-Pinto, N.C.; Bohr, V.A. DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA. Nucleic Acids Res. 2004, 32, 2181-92.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 2181-2192
-
-
Stuart, J.A.1
Hashiguchi, K.2
Wilson 3rd, D.M.3
Copeland, W.C.4
Souza-Pinto, N.C.5
Bohr, V.A.6
-
17
-
-
0035101674
-
Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer
-
Carrodeguas, J.A.; Theis, K.; Bogenhagen, D.F.; Kisker, C. Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer. Mol. Cell 2001, 7, 43-54.
-
(2001)
Mol. Cell
, vol.7
, pp. 43-54
-
-
Carrodeguas, J.A.1
Theis, K.2
Bogenhagen, D.F.3
Kisker, C.4
-
18
-
-
34948819776
-
The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits
-
Yakubovskaya, E.; Lukin, M.; Chen, Z.; Berriman, J.; Wall, J.S.; Kobayashi, R.; Kisker, C.; Bogenhagen, D.F. The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits. EMBO J. 2007, 26, 4283-91
-
(2007)
EMBO J
, vol.26
, pp. 4283-4291
-
-
Yakubovskaya, E.1
Lukin, M.2
Chen, Z.3
Berriman, J.4
Wall, J.S.5
Kobayashi, R.6
Kisker, C.7
Bogenhagen, D.F.8
-
19
-
-
0035914329
-
The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit
-
Longley, M.J.; Nguyen, D.; Kunkel, T.A.; Copeland, W.C. The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. J. Biol. Chem. 2001, 276, 38555-62.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 38555-38562
-
-
Longley, M.J.1
Nguyen, D.2
Kunkel, T.A.3
Copeland, W.C.4
-
20
-
-
0034943967
-
Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions
-
Van Goethem, G.; Dermaut, B.; Lofgren, A.; Martin, J.J.; Van Broeckhoven, C. Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions. Nat. Genet. 2001, 28, 211-2.
-
(2001)
Nat. Genet
, vol.28
, pp. 211-212
-
-
Van Goethem, G.1
Dermaut, B.2
Lofgren, A.3
Martin, J.J.4
Van Broeckhoven, C.5
-
21
-
-
33749001168
-
Mitochondrial DNA polymerase-gamma and human disease
-
Hudson, G.; Chinnery, P.F. Mitochondrial DNA polymerase-gamma and human disease. Hum. Mol. Genet. 2006, 2, R244-52.
-
(2006)
Hum. Mol. Genet
, vol.2
-
-
Hudson, G.1
Chinnery, P.F.2
-
22
-
-
23644449234
-
Consequences of mutations in human DNA polymerase gamma
-
Longley, M.J.; Graziewicz, M.A.; Bienstock, R.J.; Copeland, W.C. Consequences of mutations in human DNA polymerase gamma. Gene. 2005, 354, 125-31.
-
(2005)
Gene
, vol.354
, pp. 125-131
-
-
Longley, M.J.1
Graziewicz, M.A.2
Bienstock, R.J.3
Copeland, W.C.4
-
23
-
-
0037013234
-
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis
-
Ponamarev, M.V.; Longley, M.J.; Nguyen, D.; Kunkel, T.A.; Copeland, W.C. Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis. J. Biol. Chem. 2002, 277, 15225-8.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 15225-15228
-
-
Ponamarev, M.V.1
Longley, M.J.2
Nguyen, D.3
Kunkel, T.A.4
Copeland, W.C.5
-
24
-
-
35548972018
-
The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2′-deoxyguanosine
-
Graziewicz, M.A.; Bienstock, R.J.; Copeland, W.C. The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2′-deoxyguanosine. Hum. Mol. Genet. 2007, 16, 2729-39.
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 2729-2739
-
-
Graziewicz, M.A.1
Bienstock, R.J.2
Copeland, W.C.3
-
25
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic, A.; Wredenberg, A.; Falkenberg, M.; Spelbrink, J.N.; Rovio, A.T.; Bruder, C.E.; Bohlooly, Y.M.; Gidlof, S.; Oldfors, A.; Wibom, R.; Tornell, J.; Jacobs, H.T.; Larsson, N.G. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 2004, 429, 417-23.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
26
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth, G.C.; Hiona, A.; Pugh, T.D.; Someya, S.; Panzer, K.; Wohlgemuth, S.E.; Hofer, T.; Seo, A.Y.; Sullivan, R.; Jobling, W.A.; Morrow, J.D.; Van Remmen, H.; Sedivy, J.M.; Yamasoba, T.; Tanokura, M.; Weindruch, R.; Leeuwenburgh, C.; Prolla, T.A. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 2005, 309, 481-4.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
Van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
27
-
-
0034667349
-
Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis
-
Zhang, D.; Mott, J.L.; Chang, S.W.; Denniger, G.; Feng, Z.; Zassenhaus, H.P. Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis. Genomics 2000, 69, 151-61.
-
(2000)
Genomics
, vol.69
, pp. 151-161
-
-
Zhang, D.1
Mott, J.L.2
Chang, S.W.3
Denniger, G.4
Feng, Z.5
Zassenhaus, H.P.6
-
28
-
-
41349087783
-
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
-
Vermulst, M.; Wanagat, J.; Kujoth, G.C.; Bielas, J.H.; Rabinovitch, P.S.; Prolla, T.A.; Loeb, L.A. DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice. Nat Genet 2008, 40, 392-4.
-
(2008)
Nat Genet
, vol.40
, pp. 392-394
-
-
Vermulst, M.1
Wanagat, J.2
Kujoth, G.C.3
Bielas, J.H.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
29
-
-
34047116291
-
Mitochondrial point mutations do not limit the natural lifespan of mice
-
Vermulst, M.; Bielas, J.H.; Kujoth, G.C.; Ladiges, W.C.; Rabinovitch, P.S.; Prolla, T.A.; Loeb, L.A. Mitochondrial point mutations do not limit the natural lifespan of mice. Nat. Genet 2007, 39, 540-3.
-
(2007)
Nat. Genet
, vol.39
, pp. 540-543
-
-
Vermulst, M.1
Bielas, J.H.2
Kujoth, G.C.3
Ladiges, W.C.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
30
-
-
0344011127
-
-
Seki, M.; Marini, F.; Wood, R.D. POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Nucleic Acids. Res. 2003, 31, 6117-26.
-
Seki, M.; Marini, F.; Wood, R.D. POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Nucleic Acids. Res. 2003, 31, 6117-26.
-
-
-
-
31
-
-
46349087126
-
Low-fidelity DNA synthesis by human DNA polymerase theta
-
Arana, M.E.; Seki, M.; Wood, R.D.; Rogozin, I.B.; Kunkel, T.A. Low-fidelity DNA synthesis by human DNA polymerase theta. Nucleic Acids Res. 2008,
-
(2008)
Nucleic Acids Res
-
-
Arana, M.E.1
Seki, M.2
Wood, R.D.3
Rogozin, I.B.4
Kunkel, T.A.5
-
32
-
-
10044288293
-
High-efficiency bypass of DNA damage by human DNA polymerase Q
-
Seki, M.; Masutani, C.; Yang, L.W.; Schuffert, A.; Iwai, S.; Bahar, I.; Wood, R.D. High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J. 2004, 23, 4484-94.
-
(2004)
EMBO J
, vol.23
, pp. 4484-4494
-
-
Seki, M.1
Masutani, C.2
Yang, L.W.3
Schuffert, A.4
Iwai, S.5
Bahar, I.6
Wood, R.D.7
-
33
-
-
33749315817
-
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage
-
Yoshimura, M.; Kohzaki, M.; Nakamura, J.; Asagoshi, K.; Sonoda, E.; Hou, E.; Prasad, R.; Wilson, S.H.; Tano, K.; Yasui, A.; Lan, L.; Seki, M.; Wood, R.D.; Arakawa, H.; Buerstedde, J.M.; Hochegger, H.; Okada, T.; Hiraoka, M.; Takeda, S. Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Mol. Cell 2006, 24, 115-25.
-
(2006)
Mol. Cell
, vol.24
, pp. 115-125
-
-
Yoshimura, M.1
Kohzaki, M.2
Nakamura, J.3
Asagoshi, K.4
Sonoda, E.5
Hou, E.6
Prasad, R.7
Wilson, S.H.8
Tano, K.9
Yasui, A.10
Lan, L.11
Seki, M.12
Wood, R.D.13
Arakawa, H.14
Buerstedde, J.M.15
Hochegger, H.16
Okada, T.17
Hiraoka, M.18
Takeda, S.19
-
34
-
-
36549043013
-
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct
-
Seki, M.; Wood, R.D. DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. DNA Repair (Amst) 2008, 7, 119-27.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 119-127
-
-
Seki, M.1
Wood, R.D.2
-
35
-
-
33750028041
-
-
Masuda, K.; Ouchida, R.; Hikida, M.; Nakayama, M.; Ohara, O.; Kurosaki, T.; J, O.W. Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes. DNA Repair (Amst) 2006, 5, 1384-91.
-
Masuda, K.; Ouchida, R.; Hikida, M.; Nakayama, M.; Ohara, O.; Kurosaki, T.; J, O.W. Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes. DNA Repair (Amst) 2006, 5, 1384-91.
-
-
-
-
36
-
-
25444441796
-
-
Masuda, K.; Ouchida, R.; Takeuchi, A.; Saito, T.; Koseki, H.; Kawamura, K.; Tagawa, M.; Tokuhisa, T.; Azuma, T.; J, O.W. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc. Natl. Acad. Sci. USA 2005, 102, 13986-91.
-
Masuda, K.; Ouchida, R.; Takeuchi, A.; Saito, T.; Koseki, H.; Kawamura, K.; Tagawa, M.; Tokuhisa, T.; Azuma, T.; J, O.W. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc. Natl. Acad. Sci. USA 2005, 102, 13986-91.
-
-
-
-
37
-
-
34547114028
-
-
Masuda, K.; Ouchida, R.; Hikida, M.; Kurosaki, T.; Yokoi, M.; Masutani, C.; Seki, M.; Wood, R.D.; Hanaoka, F.; J, O.W. DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. J. Biol. Chem. 2007, 282, 17387-94.
-
Masuda, K.; Ouchida, R.; Hikida, M.; Kurosaki, T.; Yokoi, M.; Masutani, C.; Seki, M.; Wood, R.D.; Hanaoka, F.; J, O.W. DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. J. Biol. Chem. 2007, 282, 17387-94.
-
-
-
-
38
-
-
27744483444
-
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation
-
Zan, H.; Shima, N.; Xu, Z.; Al-Qahtani, A.; Evinger Iii, A.J.; Zhong, Y.; Schimenti, J.C.; Casali, P. The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J.2005, 24, 3757-69.
-
(2005)
EMBO J
, vol.24
, pp. 3757-3769
-
-
Zan, H.1
Shima, N.2
Xu, Z.3
Al-Qahtani, A.4
Evinger Iii, A.J.5
Zhong, Y.6
Schimenti, J.C.7
Casali, P.8
-
39
-
-
48149091758
-
-
Marmoto, s.a.; Saribasak, h.; Yokoi, M.; hanaoka, F.; Gearhart, P.J. Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. DNA Repair (Amst) 2008, In press,
-
Marmoto, s.a.; Saribasak, h.; Yokoi, M.; hanaoka, F.; Gearhart, P.J. Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. DNA Repair (Amst) 2008, In press,
-
-
-
-
40
-
-
0042357095
-
-
Marini, F.; Kim, N.; Schuffert, A.; Wood, R.D. POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. J. Biol. Chem.2003, 278, 32014-9
-
Marini, F.; Kim, N.; Schuffert, A.; Wood, R.D. POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. J. Biol. Chem.2003, 278, 32014-9
-
-
-
-
41
-
-
33747666822
-
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol
-
Takata, K.; Shimizu, T.; Iwai, S.; Wood, R.D. Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J. Biol. Chem. 2006, 281, 23445-55.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 23445-23455
-
-
Takata, K.1
Shimizu, T.2
Iwai, S.3
Wood, R.D.4
-
42
-
-
33846246423
-
A unique error signature for human DNA polymerase nu
-
Arana, M.E.; Takata, K.; Garcia-Diaz, M.; Wood, R.D.; Kunkel, T.A. A unique error signature for human DNA polymerase nu. DNA Repair (Amst) 2007, 6, 213-23.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 213-223
-
-
Arana, M.E.1
Takata, K.2
Garcia-Diaz, M.3
Wood, R.D.4
Kunkel, T.A.5
-
43
-
-
0035369086
-
Structure of the replicating complex of a pol alpha family DNA polymerase
-
Franklin, M.C.; Wang, J.; Steitz, T.A. Structure of the replicating complex of a pol alpha family DNA polymerase. Cell 2001, 105, 657-67.
-
(2001)
Cell
, vol.105
, pp. 657-667
-
-
Franklin, M.C.1
Wang, J.2
Steitz, T.A.3
-
44
-
-
34547175132
-
Structures of phi29 DNA polymerase complexed with substrate: The mechanism of translocation in B-family polymerases
-
Berman, A.J.; Kamtekar, S.; Goodman, J.L.; Lazaro, J.M.; de Vega, M.; Blanco, L.; Salas, M.; Steitz, T.A. Structures of phi29 DNA polymerase complexed with substrate: The mechanism of translocation in B-family polymerases. EMBO J. 2007, 26, 3494-505.
-
(2007)
EMBO J
, vol.26
, pp. 3494-3505
-
-
Berman, A.J.1
Kamtekar, S.2
Goodman, J.L.3
Lazaro, J.M.4
de Vega, M.5
Blanco, L.6
Salas, M.7
Steitz, T.A.8
-
45
-
-
15844376385
-
Incorporation of thymidine into deoxyribonucleic acid by enzymes from rat tissues
-
Bollum, F.J.; Potter, V.R. Incorporation of thymidine into deoxyribonucleic acid by enzymes from rat tissues. J. Biol. Chem. 1958, 233, 478-82.
-
(1958)
J. Biol. Chem
, vol.233
, pp. 478-482
-
-
Bollum, F.J.1
Potter, V.R.2
-
46
-
-
33746923134
-
Deoxynucleotide-Polymerizing Enzymes of Calf Thymus Gland. I. Large Scale Purification of Terminal and Replicative Deoxynucleotidyl Transferases
-
Yoneda, M.; Bollum, F.J. Deoxynucleotide-Polymerizing Enzymes of Calf Thymus Gland. I. Large Scale Purification of Terminal and Replicative Deoxynucleotidyl Transferases. J. Biol. Chem. 1965, 240, 3385-91.
-
(1965)
J. Biol. Chem
, vol.240
, pp. 3385-3391
-
-
Yoneda, M.1
Bollum, F.J.2
-
47
-
-
0016701968
-
Nomenclature of eukaryotic DNA polymerases
-
Weissbach, A.; Baltimore, D.; Bollum, F.; Gallo, R.; Korn, D. Nomenclature of eukaryotic DNA polymerases. Science 1975, 190, 401-2.
-
(1975)
Science
, vol.190
, pp. 401-402
-
-
Weissbach, A.1
Baltimore, D.2
Bollum, F.3
Gallo, R.4
Korn, D.5
-
48
-
-
0017104954
-
Evidence that DNA polymerase-alpha of calf thymus contains a subunit of molecular weight 155000
-
Holmes, A.M.; Hesslewood, I.P.; Johnston, I.R. Evidence that DNA polymerase-alpha of calf thymus contains a subunit of molecular weight 155000. Eur. J. Biochem. 1976, 62, 229-35.
-
(1976)
Eur. J. Biochem
, vol.62
, pp. 229-235
-
-
Holmes, A.M.1
Hesslewood, I.P.2
Johnston, I.R.3
-
49
-
-
0022180425
-
Initiation of DNA synthesis by the calf thymus DNA polymerase-primase complex
-
Holmes, A.M.; Cheriathundam, E.; Bollum, F.J.; Chang, L.M. Initiation of DNA synthesis by the calf thymus DNA polymerase-primase complex. J. Biol. Chem. 1985, 260, 10840-6.
-
(1985)
J. Biol. Chem
, vol.260
, pp. 10840-10846
-
-
Holmes, A.M.1
Cheriathundam, E.2
Bollum, F.J.3
Chang, L.M.4
-
50
-
-
0020742292
-
Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster
-
Kaguni, L.S.; Rossignol, J.M.; Conaway, R.C.; Lehman, I.R. Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 1983, 80, 2221-5.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 2221-2225
-
-
Kaguni, L.S.1
Rossignol, J.M.2
Conaway, R.C.3
Lehman, I.R.4
-
51
-
-
0024259807
-
The yeast DNA polymerase-primase complex: Genes and proteins
-
Plevani, P.; Foiani, M.; Muzi Falconi, M.; Pizzagalli, A.; Santocanale, C.; Francesconi, S.; Valsasnini, P.; Comedini, A.; Piatti, S.; Lucchini, G. The yeast DNA polymerase-primase complex: Genes and proteins. Biochim. Biophys. Acta 1988, 951, 268-73.
-
(1988)
Biochim. Biophys. Acta
, vol.951
, pp. 268-273
-
-
Plevani, P.1
Foiani, M.2
Muzi Falconi, M.3
Pizzagalli, A.4
Santocanale, C.5
Francesconi, S.6
Valsasnini, P.7
Comedini, A.8
Piatti, S.9
Lucchini, G.10
-
53
-
-
0028223787
-
DNA replication in vitro by recombinant DNA-polymerase-alpha-primase
-
Stadlbauer, F.; Brueckner, A.; Rehfuess, C.; Eckerskorn, C.; Lottspeich, F.; Forster, V.; Tseng, B.Y.; Nasheuer, H.P. DNA replication in vitro by recombinant DNA-polymerase-alpha-primase. Eur. J. Biochem. 1994, 222, 781-93.
-
(1994)
Eur. J. Biochem
, vol.222
, pp. 781-793
-
-
Stadlbauer, F.1
Brueckner, A.2
Rehfuess, C.3
Eckerskorn, C.4
Lottspeich, F.5
Forster, V.6
Tseng, B.Y.7
Nasheuer, H.P.8
-
54
-
-
0025781295
-
Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus
-
Weiser, T.; Gassmann, M.; Thommes, P.; Ferrari, E.; Hafkemeyer, P.; Hubscher, U. Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. J. Biol. Chem. 1991, 266, 10420-8.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 10420-10428
-
-
Weiser, T.1
Gassmann, M.2
Thommes, P.3
Ferrari, E.4
Hafkemeyer, P.5
Hubscher, U.6
-
55
-
-
0024562306
-
Human DNA polymerase alpha: Predicted functional domains and relationships with viral DNA polymerases
-
Wang, T.S.; Wong, S.W.; Korn, D. Human DNA polymerase alpha: Predicted functional domains and relationships with viral DNA polymerases. FASEB J. 1989, 3, 14-21.
-
(1989)
FASEB J
, vol.3
, pp. 14-21
-
-
Wang, T.S.1
Wong, S.W.2
Korn, D.3
-
56
-
-
0023707852
-
Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases
-
Wong, S.W.; Wahl, A.F.; Yuan, P.M.; Arai, N.; Pearson, B.E.; Arai, K.; Korn, D.; Hunkapiller, M.W.; Wang, T.S. Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. EMBO J. 1988, 7, 37-47.
-
(1988)
EMBO J
, vol.7
, pp. 37-47
-
-
Wong, S.W.1
Wahl, A.F.2
Yuan, P.M.3
Arai, N.4
Pearson, B.E.5
Arai, K.6
Korn, D.7
Hunkapiller, M.W.8
Wang, T.S.9
-
57
-
-
0027379095
-
Enzymatic characterization of the individual mammalian primase subunits reveals a biphasic mechanism for initiation of DNA replication
-
Copeland, W.C.; Wang, T.S. Enzymatic characterization of the individual mammalian primase subunits reveals a biphasic mechanism for initiation of DNA replication. J. Biol. Chem. 1993, 268, 26179-89.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 26179-26189
-
-
Copeland, W.C.1
Wang, T.S.2
-
58
-
-
0036312117
-
Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replication
-
Ott, R.D.; Rehfuess, C.; Podust, V.N.; Clark, J.E.; Fanning, E. Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replication. Mol. Cell Biol. 2002, 22, 5669-78.
-
(2002)
Mol. Cell Biol
, vol.22
, pp. 5669-5678
-
-
Ott, R.D.1
Rehfuess, C.2
Podust, V.N.3
Clark, J.E.4
Fanning, E.5
-
59
-
-
0027164165
-
Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis
-
Copeland, W.C.; Lam, N.K.; Wang, T.S. Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis. J. Biol. Chem. 1993, 268, 11041-9.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 11041-11049
-
-
Copeland, W.C.1
Lam, N.K.2
Wang, T.S.3
-
60
-
-
30944452765
-
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta
-
Pavlov, Y.I.; Frahm, C.; Nick McElhinny, S.A.; Niimi, A.; Suzuki, M.; Kunkel, T.A. Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Curr. Biol. 2006, 16, 202-7.
-
(2006)
Curr. Biol
, vol.16
, pp. 202-207
-
-
Pavlov, Y.I.1
Frahm, C.2
Nick McElhinny, S.A.3
Niimi, A.4
Suzuki, M.5
Kunkel, T.A.6
-
61
-
-
0024429338
-
Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae
-
Kunkel, T.A.; Hamatake, R.K.; Motto-Fox, J.; Fitzgerald, M.P.; Sugino, A. Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. Mol. Cell Biol. 1989, 9, 4447-58.
-
(1989)
Mol. Cell Biol
, vol.9
, pp. 4447-4458
-
-
Kunkel, T.A.1
Hamatake, R.K.2
Motto-Fox, J.3
Fitzgerald, M.P.4
Sugino, A.5
-
62
-
-
0025008702
-
DNA polymerase alpha defect in the N syndrome
-
Floy, K.M.; Hess, R.O.; Meisner, L.F. DNA polymerase alpha defect in the N syndrome. Am. J. Med. Genet. 1990, 35, 301-5
-
(1990)
Am. J. Med. Genet
, vol.35
, pp. 301-305
-
-
Floy, K.M.1
Hess, R.O.2
Meisner, L.F.3
-
63
-
-
0035997349
-
Eukaryotic DNA polymerases
-
Hubscher, U.; Maga, G.; Spadari, S. Eukaryotic DNA polymerases. Annu. Rev. Biochem. 2002, 71, 133-63.
-
(2002)
Annu. Rev. Biochem
, vol.71
, pp. 133-163
-
-
Hubscher, U.1
Maga, G.2
Spadari, S.3
-
64
-
-
0017169587
-
A new mammalian DNA polymerase with 3′ to 5′ exonuclease activity: DNA polymerase delta
-
Byrnes, J.J.; Downey, K.M.; Black, V.L.; So, A.G. A new mammalian DNA polymerase with 3′ to 5′ exonuclease activity: DNA polymerase delta. Biochemistry 1976, 15, 2817-23
-
(1976)
Biochemistry
, vol.15
, pp. 2817-2823
-
-
Byrnes, J.J.1
Downey, K.M.2
Black, V.L.3
So, A.G.4
-
65
-
-
42949119884
-
Division of labor at the eukaryotic replication fork
-
Nick McElhinny, S.A.; Gordenin, D.A.; Stith, C.M.; Burgers, P.M.; Kunkel, T.A. Division of labor at the eukaryotic replication fork. Mol. Cell 2008, 30, 137-44.
-
(2008)
Mol. Cell
, vol.30
, pp. 137-144
-
-
Nick McElhinny, S.A.1
Gordenin, D.A.2
Stith, C.M.3
Burgers, P.M.4
Kunkel, T.A.5
-
66
-
-
38949107602
-
DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension
-
Maloisel, L.; Fabre, F.; Gangloff, S. DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension. Mol. Cell Biol. 2008, 28, 1373-82.
-
(2008)
Mol. Cell Biol
, vol.28
, pp. 1373-1382
-
-
Maloisel, L.1
Fabre, F.2
Gangloff, S.3
-
67
-
-
34047132773
-
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3′-end proximal lesions
-
Parsons, J.L.; Preston, B.D.; O'Connor, T.R.; Dianov, G.L. DNA polymerase delta-dependent repair of DNA single strand breaks containing 3′-end proximal lesions. Nucleic Acids Res. 2007, 35, 1054-63.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1054-1063
-
-
Parsons, J.L.1
Preston, B.D.2
O'Connor, T.R.3
Dianov, G.L.4
-
68
-
-
0034705617
-
Identification of a fourth subunit of mammalian DNA polymerase delta
-
Liu, L.; Mo, J.; Rodriguez-Belmonte, E.M.; Lee, M.Y. Identification of a fourth subunit of mammalian DNA polymerase delta. J. Biol. Chem. 2000, 275, 18739-44.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 18739-18744
-
-
Liu, L.1
Mo, J.2
Rodriguez-Belmonte, E.M.3
Lee, M.Y.4
-
69
-
-
0026573499
-
Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta
-
Yang, C.L.; Chang, L.S.; Zhang, P.; Hao, H.; Zhu, L.; Toomey, N.L.; Lee, M.Y. Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta. Nucleic Acids Res. 1992, 20, 735-45.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 735-745
-
-
Yang, C.L.1
Chang, L.S.2
Zhang, P.3
Hao, H.4
Zhu, L.5
Toomey, N.L.6
Lee, M.Y.7
-
70
-
-
52649182222
-
The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase {delta}
-
Selak, N.; Bachrati, C.Z.; Shevelev, I.; Dietschy, T.; van Loon, B.; Jacob, A.; Hubscher, U.; Hoheisel, J.D.; Hickson, I.D.; Stagljar, I. The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase {delta}. Nucleic Acids Res. 2008,
-
(2008)
Nucleic Acids Res
-
-
Selak, N.1
Bachrati, C.Z.2
Shevelev, I.3
Dietschy, T.4
van Loon, B.5
Jacob, A.6
Hubscher, U.7
Hoheisel, J.D.8
Hickson, I.D.9
Stagljar, I.10
-
71
-
-
23844522523
-
Saccharomyces cerevisiae DNA polymerase delta: High fidelity for base substitutions but lower fidelity for single- and multi-base deletions
-
Fortune, J.M.; Pavlov, Y.I.; Welch, C.M.; Johansson, E.; Burgers, P.M.; Kunkel, T.A. Saccharomyces cerevisiae DNA polymerase delta: High fidelity for base substitutions but lower fidelity for single- and multi-base deletions. J. Biol. Chem. 2005, 280, 29980-7.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 29980-29987
-
-
Fortune, J.M.1
Pavlov, Y.I.2
Welch, C.M.3
Johansson, E.4
Burgers, P.M.5
Kunkel, T.A.6
-
72
-
-
35648999490
-
Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis
-
Venkatesan, R.N.; Treuting, P.M.; Fuller, E.D.; Goldsby, R.E.; Norwood, T.H.; Gooley, T.A.; Ladiges, W.C.; Preston, B.D.; Loeb, L.A. Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Mol. Cell Biol. 2007, 27, 7669-82.
-
(2007)
Mol. Cell Biol
, vol.27
, pp. 7669-7682
-
-
Venkatesan, R.N.1
Treuting, P.M.2
Fuller, E.D.3
Goldsby, R.E.4
Norwood, T.H.5
Gooley, T.A.6
Ladiges, W.C.7
Preston, B.D.8
Loeb, L.A.9
-
73
-
-
0037180555
-
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading
-
Goldsby, R.E.; Hays, L.E.; Chen, X.; Olmsted, E.A.; Slayton, W.B.; Spangrude, G.J.; Preston, B.D. High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Proc. Natl. Acad. Sci. USA 2002, 99, 15560-5.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15560-15565
-
-
Goldsby, R.E.1
Hays, L.E.2
Chen, X.3
Olmsted, E.A.4
Slayton, W.B.5
Spangrude, G.J.6
Preston, B.D.7
-
74
-
-
0028859670
-
Polymerase delta variants in RER colorectal tumours
-
da Costa, L.T.; Liu, B.; el-Deiry, W.; Hamilton, S.R.; Kinzler, K.W.; Vogelstein, B.; Markowitz, S.; Willson, J.K.; de la Chapelle, A.; Downey, K.M.; et al. Polymerase delta variants in RER colorectal tumours. Nat. Genet. 1995, 9, 10-1.
-
(1995)
Nat. Genet
, vol.9
, pp. 10-11
-
-
da Costa, L.T.1
Liu, B.2
el-Deiry, W.3
Hamilton, S.R.4
Kinzler, K.W.5
Vogelstein, B.6
Markowitz, S.7
Willson, J.K.8
de la Chapelle, A.9
Downey, K.M.10
-
75
-
-
0033559182
-
Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines
-
Flohr, T.; Dai, J.C.; Buttner, J.; Popanda, O.; Hagmuller, E.; Thielmann, H.W. Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines. Int. J. Cancer 1999, 80, 919-29.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 919-929
-
-
Flohr, T.1
Dai, J.C.2
Buttner, J.3
Popanda, O.4
Hagmuller, E.5
Thielmann, H.W.6
-
76
-
-
0032712407
-
A mutation detected in DNA polymerase delta cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme
-
Popanda, O.; Flohr, T.; Fox, G.; Thielmann, H.W. A mutation detected in DNA polymerase delta cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme. J. Cancer Res. Clin. Oncol. 1999, 125, 598-608.
-
(1999)
J. Cancer Res. Clin. Oncol
, vol.125
, pp. 598-608
-
-
Popanda, O.1
Flohr, T.2
Fox, G.3
Thielmann, H.W.4
-
77
-
-
34447336941
-
Yeast DNA polymerase epsilon participates in leading-strand DNA replication
-
Pursell, Z.F.; Isoz, I.; Lundstrom, E.B.; Johansson, E.; Kunkel, T.A. Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science 2007, 317, 127-30.
-
(2007)
Science
, vol.317
, pp. 127-130
-
-
Pursell, Z.F.1
Isoz, I.2
Lundstrom, E.B.3
Johansson, E.4
Kunkel, T.A.5
-
78
-
-
0034725647
-
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon
-
Li, Y.; Pursell, Z.F.; Linn, S. Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J. Biol. Chem. 2000, 275, 23247-52.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 23247-23252
-
-
Li, Y.1
Pursell, Z.F.2
Linn, S.3
-
79
-
-
0033529497
-
Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain
-
Dua, R.; Levy, D.L.; Campbell, J.L. Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain. J. Biol. Chem. 1999, 274, 22283-8.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 22283-22288
-
-
Dua, R.1
Levy, D.L.2
Campbell, J.L.3
-
80
-
-
0034805293
-
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta
-
Pavlov, Y.I.; Shcherbakova, P.V.; Kunkel, T.A. In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta. Genetics 2001, 159, 47-64.
-
(2001)
Genetics
, vol.159
, pp. 47-64
-
-
Pavlov, Y.I.1
Shcherbakova, P.V.2
Kunkel, T.A.3
-
81
-
-
0028965151
-
Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA
-
Shivji, M.K.; Podust, V.N.; Hubscher, U.; Wood, R.D. Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA. Biochemistry 1995, 34, 5011-7.
-
(1995)
Biochemistry
, vol.34
, pp. 5011-5017
-
-
Shivji, M.K.1
Podust, V.N.2
Hubscher, U.3
Wood, R.D.4
-
82
-
-
0033585087
-
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon
-
Pascucci, B.; Stucki, M.; Jonsson, Z.O.; Dogliotti, E.; Hubscher, U. Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon. J. Biol. Chem. 1999, 274, 33696-702.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 33696-33702
-
-
Pascucci, B.1
Stucki, M.2
Jonsson, Z.O.3
Dogliotti, E.4
Hubscher, U.5
-
83
-
-
30044434363
-
Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy
-
Asturias, F.J.; Cheung, I.K.; Sabouri, N.; Chilkova, O.; Wepplo, D.; Johansson, E. Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy. Nat. Struct. Mol. Biol. 2006, 13, 35-43.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 35-43
-
-
Asturias, F.J.1
Cheung, I.K.2
Sabouri, N.3
Chilkova, O.4
Wepplo, D.5
Johansson, E.6
-
84
-
-
0029952294
-
Thymine-thymine dimer bypass by yeast DNA polymerase zeta
-
Nelson, J.R.; Lawrence, C.W.; Hinkle, D.C. Thymine-thymine dimer bypass by yeast DNA polymerase zeta. Science 1996, 272, 1646-9.
-
(1996)
Science
, vol.272
, pp. 1646-1649
-
-
Nelson, J.R.1
Lawrence, C.W.2
Hinkle, D.C.3
-
85
-
-
0032499748
-
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta
-
Gibbs, P.E.; McGregor, W.G.; Maher, V.M.; Nisson, P.; Lawrence, C.W. A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Proc. Natl. Acad. Sci. USA 1998, 95, 6876-80.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6876-6880
-
-
Gibbs, P.E.1
McGregor, W.G.2
Maher, V.M.3
Nisson, P.4
Lawrence, C.W.5
-
86
-
-
31544434491
-
Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells
-
Wittschieben, J.P.; Reshmi, S.C.; Gollin, S.M.; Wood, R.D. Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. Cancer Res. 2006, 66, 134-42.
-
(2006)
Cancer Res
, vol.66
, pp. 134-142
-
-
Wittschieben, J.P.1
Reshmi, S.C.2
Gollin, S.M.3
Wood, R.D.4
-
87
-
-
54149096921
-
Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta
-
Brondello, J.M.; Pillaire, M.J.; Rodriguez, C.; Gourraud, P.A.; Selves, J.; Cazaux, C.; Piette, J. Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta. Oncogene 2008,
-
(2008)
Oncogene
-
-
Brondello, J.M.1
Pillaire, M.J.2
Rodriguez, C.3
Gourraud, P.A.4
Selves, J.5
Cazaux, C.6
Piette, J.7
-
88
-
-
9144251970
-
Gene expression profiling identifies clinically relevant subtypes of prostate cancer
-
Lapointe, J.; Li, C.; Higgins, J.P.; van de Rijn, M.; Bair, E.; Montgomery, K.; Ferrari, M.; Egevad, L.; Rayford, W.; Bergerheim, U.; Ekman, P.; DeMarzo, A.M.; Tibshirani, R.; Botstein, D.; Brown, P.O.; Brooks, J.D.; Pollack, J.R. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc. Natl. Acad.Sci. USA 2004, 101, 811-6.
-
(2004)
Proc. Natl. Acad.Sci. USA
, vol.101
, pp. 811-816
-
-
Lapointe, J.1
Li, C.2
Higgins, J.P.3
van de Rijn, M.4
Bair, E.5
Montgomery, K.6
Ferrari, M.7
Egevad, L.8
Rayford, W.9
Bergerheim, U.10
Ekman, P.11
DeMarzo, A.M.12
Tibshirani, R.13
Botstein, D.14
Brown, P.O.15
Brooks, J.D.16
Pollack, J.R.17
-
89
-
-
2642561028
-
Immortalized mouse cell lines that lack a functional Rev3 gene are hypersensitive to UV irradiation and cisplatin treatment
-
Zander, L.; Bemark, M. Immortalized mouse cell lines that lack a functional Rev3 gene are hypersensitive to UV irradiation and cisplatin treatment. DNA Repair (Amst) 2004, 3, 743-52.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 743-752
-
-
Zander, L.1
Bemark, M.2
-
90
-
-
0141542616
-
Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta
-
Diaz, M.; Watson, N.B.; Turkington, G.; Verkoczy, L.K.; Klinman, N.R.; McGregor, W.G. Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta. Mol. Cancer Res. 2003, 1, 836-47.
-
(2003)
Mol. Cancer Res
, vol.1
, pp. 836-847
-
-
Diaz, M.1
Watson, N.B.2
Turkington, G.3
Verkoczy, L.K.4
Klinman, N.R.5
McGregor, W.G.6
-
91
-
-
0036295264
-
-
J, O.W.; Kajiwara, K.; Kawamura, K.; Kimura, M.; Miyagishima, H.; Koseki, H.; Tagawa, M. An essential role for REV3 in mammalian cell survival: Absence of REV3 induces p53-independent embryonic death. Biochem. Biophys. Res. Commun. 2002, 293, 1132-7.
-
J, O.W.; Kajiwara, K.; Kawamura, K.; Kimura, M.; Miyagishima, H.; Koseki, H.; Tagawa, M. An essential role for REV3 in mammalian cell survival: Absence of REV3 induces p53-independent embryonic death. Biochem. Biophys. Res. Commun. 2002, 293, 1132-7.
-
-
-
-
92
-
-
0034609725
-
Disruption of the Rev31-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality
-
Esposito, G.; Godindagger, I.; Klein, U.; Yaspo, M.L.; Cumano, A.; Rajewsky, K. Disruption of the Rev31-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality. Curr. Biol. 2000, 10, 1221-4.
-
(2000)
Curr. Biol
, vol.10
, pp. 1221-1224
-
-
Esposito, G.1
Godindagger, I.2
Klein, U.3
Yaspo, M.L.4
Cumano, A.5
Rajewsky, K.6
-
93
-
-
0034609760
-
Disruption of the developmentally regulated Rev31 gene causes embryonic lethality
-
Wittschieben, J.; Shivji, M.K.; Lalani, E.; Jacobs, M.A.; Marini, F.; Gearhart, P.J.; Rosewell, I.; Stamp, G.; Wood, R.D. Disruption of the developmentally regulated Rev31 gene causes embryonic lethality. Curr. Biol. 2000, 10, 1217-20.
-
(2000)
Curr. Biol
, vol.10
, pp. 1217-1220
-
-
Wittschieben, J.1
Shivji, M.K.2
Lalani, E.3
Jacobs, M.A.4
Marini, F.5
Gearhart, P.J.6
Rosewell, I.7
Stamp, G.8
Wood, R.D.9
-
94
-
-
0034609744
-
Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro
-
Bemark, M.; Khamlichi, A.A.; Davies, S.L.; Neuberger, M.S. Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro. Curr. Biol. 2000, 10, 1213-6.
-
(2000)
Curr. Biol
, vol.10
, pp. 1213-1216
-
-
Bemark, M.1
Khamlichi, A.A.2
Davies, S.L.3
Neuberger, M.S.4
-
95
-
-
23044453811
-
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining
-
Nick McElhinny, S.A.; Havener, J.M.; Garcia-Diaz, M.; Juarez, R.; Bebenek, K.; Kee, B.L.; Blanco, L.; Kunkel, T.A.; Ramsden, D.A. A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Mol. Cell 2005, 19, 357-66.
-
(2005)
Mol. Cell
, vol.19
, pp. 357-366
-
-
Nick McElhinny, S.A.1
Havener, J.M.2
Garcia-Diaz, M.3
Juarez, R.4
Bebenek, K.5
Kee, B.L.6
Blanco, L.7
Kunkel, T.A.8
Ramsden, D.A.9
-
96
-
-
0029817866
-
Crystal structures of human DNA polymerase beta complexed with DNA: Implications for catalytic mechanism, processivity, and fidelity
-
Pelletier, H.; Sawaya, M.R.; Wolfle, W.; Wilson, S.H.; Kraut, J. Crystal structures of human DNA polymerase beta complexed with DNA: Implications for catalytic mechanism, processivity, and fidelity. Biochemistry 1996, 35, 12742-61.
-
(1996)
Biochemistry
, vol.35
, pp. 12742-12761
-
-
Pelletier, H.1
Sawaya, M.R.2
Wolfle, W.3
Wilson, S.H.4
Kraut, J.5
-
97
-
-
0030930760
-
Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
-
Sawaya, M.R.; Prasad, R.; Wilson, S.H.; Kraut, J.; Pelletier, H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: Evidence for an induced fit mechanism. Biochemistry 1997, 36, 11205-15.
-
(1997)
Biochemistry
, vol.36
, pp. 11205-11215
-
-
Sawaya, M.R.1
Prasad, R.2
Wilson, S.H.3
Kraut, J.4
Pelletier, H.5
-
98
-
-
0030030379
-
Requirement of mammalian DNA polymerase-beta in base-excision repair
-
Sobol, R.W.; Horton, J.K.; Kuhn, R.; Gu, H.; Singhal, R.K.; Prasad, R.; Rajewsky, K.; Wilson, S.H. Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature 1996, 379, 183-6
-
(1996)
Nature
, vol.379
, pp. 183-186
-
-
Sobol, R.W.1
Horton, J.K.2
Kuhn, R.3
Gu, H.4
Singhal, R.K.5
Prasad, R.6
Rajewsky, K.7
Wilson, S.H.8
-
99
-
-
0030957997
-
Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement for DNase IV (FEN1)
-
Klungland, A.; Lindahl, T. Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 1997, 16, 3341-8.
-
(1997)
EMBO J
, vol.16
, pp. 3341-3348
-
-
Klungland, A.1
Lindahl, T.2
-
100
-
-
0029842307
-
Reconstitution of DNA base excision-repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein
-
Kubota, Y.; Nash, R.A.; Klungland, A.; Schar, P.; Barnes, D.E.; Lindahl, T. Reconstitution of DNA base excision-repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein. EMBO J. 1996, 15, 6662-70.
-
(1996)
EMBO J
, vol.15
, pp. 6662-6670
-
-
Kubota, Y.1
Nash, R.A.2
Klungland, A.3
Schar, P.4
Barnes, D.E.5
Lindahl, T.6
-
101
-
-
0037227566
-
Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential
-
Krahn, J.M.; Beard, W.A.; Miller, H.; Grollman, A.P.; Wilson, S.H. Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential. Structure 2003, 11, 121-7.
-
(2003)
Structure
, vol.11
, pp. 121-127
-
-
Krahn, J.M.1
Beard, W.A.2
Miller, H.3
Grollman, A.P.4
Wilson, S.H.5
-
102
-
-
42949164023
-
Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation
-
Batra, V.K.; Beard, W.A.; Shock, D.D.; Pedersen, L.C.; Wilson, S.H. Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Mol. Cell 2008, 30, 315-24.
-
(2008)
Mol. Cell
, vol.30
, pp. 315-324
-
-
Batra, V.K.1
Beard, W.A.2
Shock, D.D.3
Pedersen, L.C.4
Wilson, S.H.5
-
103
-
-
33644634986
-
Structure and mechanism of DNA polymerase Beta
-
Beard, W.A.; Wilson, S.H. Structure and mechanism of DNA polymerase Beta. Chem. Rev. 2006, 106, 361-82.
-
(2006)
Chem. Rev
, vol.106
, pp. 361-382
-
-
Beard, W.A.1
Wilson, S.H.2
-
104
-
-
13944279514
-
Is there a link between DNA polymerase beta and cancer?
-
Starcevic, D.; Dalal, S.; Sweasy, J.B. Is there a link between DNA polymerase beta and cancer? Cell Cycle 2004, 3, 998-1001.
-
(2004)
Cell Cycle
, vol.3
, pp. 998-1001
-
-
Starcevic, D.1
Dalal, S.2
Sweasy, J.B.3
-
105
-
-
39149130715
-
The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient
-
Dalal, S.; Chikova, A.; Jaeger, J.; Sweasy, J.B. The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient. Nucleic Acids. Res. 2008, 36, 411-22.
-
(2008)
Nucleic Acids. Res
, vol.36
, pp. 411-422
-
-
Dalal, S.1
Chikova, A.2
Jaeger, J.3
Sweasy, J.B.4
-
106
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu, H.; Marth, J.D.; Orban, P.C.; Mossmann, H.; Rajewsky, K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994, 265, 103-6.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
107
-
-
0034654379
-
Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta
-
Sugo, N.; Aratani, Y.; Nagashima, Y.; Kubota, Y.; Koyama, H. Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta. EMBO J. 2000, 19, 1397-404.
-
(2000)
EMBO J
, vol.19
, pp. 1397-1404
-
-
Sugo, N.1
Aratani, Y.2
Nagashima, Y.3
Kubota, Y.4
Koyama, H.5
-
108
-
-
55549124181
-
Mutagenesis Is Elevated in Male Germ Cells Obtained from DNA Polymerase-beta Heterozygous Mice
-
Allen, D.; Herbert, D.C.; McMahan, C.A.; Rotrekl, V.; Sobol, R.W.; Wilson, S.H.; Walter, C.A. Mutagenesis Is Elevated in Male Germ Cells Obtained from DNA Polymerase-beta Heterozygous Mice. Biol. Reprod. 2008,
-
(2008)
Biol. Reprod
-
-
Allen, D.1
Herbert, D.C.2
McMahan, C.A.3
Rotrekl, V.4
Sobol, R.W.5
Wilson, S.H.6
Walter, C.A.7
-
109
-
-
0034714096
-
DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis
-
Garcia-Diaz, M.; Dominguez, O.; Lopez-Fernandez, L.A.; de Lera, L.T.; Saniger, M.L.; Ruiz, J.F.; Parraga, M.; Garcia-Ortiz, M.J.; Kirchhoff, T.; del Mazo, J.; Bernad, A.; Blanco, L. DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis. J. Mol. Biol. 2000, 301, 851-67.
-
(2000)
J. Mol. Biol
, vol.301
, pp. 851-867
-
-
Garcia-Diaz, M.1
Dominguez, O.2
Lopez-Fernandez, L.A.3
de Lera, L.T.4
Saniger, M.L.5
Ruiz, J.F.6
Parraga, M.7
Garcia-Ortiz, M.J.8
Kirchhoff, T.9
del Mazo, J.10
Bernad, A.11
Blanco, L.12
-
110
-
-
1542375156
-
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology
-
Garcia-Diaz, M.; Bebenek, K.; Krahn, J.M.; Blanco, L.; Kunkel, T.A.; Pedersen, L.C. A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol. Cell 2004, 13, 561-72.
-
(2004)
Mol. Cell
, vol.13
, pp. 561-572
-
-
Garcia-Diaz, M.1
Bebenek, K.2
Krahn, J.M.3
Blanco, L.4
Kunkel, T.A.5
Pedersen, L.C.6
-
111
-
-
0035860767
-
Identification of an intrinsic 5′-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: A possible role in base excision repair
-
Garcia-Diaz, M.; Bebenek, K.; Kunkel, T.A.; Blanco, L. Identification of an intrinsic 5′-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: A possible role in base excision repair. J. Biol. Chem. 2001, 276, 34659-63.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 34659-34663
-
-
Garcia-Diaz, M.1
Bebenek, K.2
Kunkel, T.A.3
Blanco, L.4
-
112
-
-
24744472268
-
DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair
-
Braithwaite, E.K.; Kedar, P.S.; Lan, L.; Polosina, Y.Y.; Asagoshi, K.; Poltoratsky, V.P.; Horton, J.K.; Miller, H.; Teebor, G.W.; Yasui, A.; Wilson, S.H. DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair. J. Biol. Chem. 2005, 280, 31641-7.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 31641-31647
-
-
Braithwaite, E.K.1
Kedar, P.S.2
Lan, L.3
Polosina, Y.Y.4
Asagoshi, K.5
Poltoratsky, V.P.6
Horton, J.K.7
Miller, H.8
Teebor, G.W.9
Yasui, A.10
Wilson, S.H.11
-
113
-
-
34247591943
-
Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells
-
Tano, K.; Nakamura, J.; Asagoshi, K.; Arakawa, H.; Sonoda, E.; Braithwaite, E.K.; Prasad, R.; Buerstedde, J.M.; Takeda, S.; Watanabe, M.; Wilson, S.H. Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. DNA Repair (Amst) 2007, 6, 869-75.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 869-875
-
-
Tano, K.1
Nakamura, J.2
Asagoshi, K.3
Arakawa, H.4
Sonoda, E.5
Braithwaite, E.K.6
Prasad, R.7
Buerstedde, J.M.8
Takeda, S.9
Watanabe, M.10
Wilson, S.H.11
-
114
-
-
4644328090
-
DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex
-
Fan, W.; Wu, X. DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex. Biochem. Biophys. Res. Commun. 2004, 323, 1328-33.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.323
, pp. 1328-1333
-
-
Fan, W.1
Wu, X.2
-
115
-
-
33745663340
-
Promiscuous mismatch extension by human DNA polymerase lambda
-
Picher, A.J.; Garcia-Diaz, M.; Bebenek, K.; Pedersen, L.C.; Kunkel, T.A.; Blanco, L. Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Res. 2006, 34, 3259-66.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3259-3266
-
-
Picher, A.J.1
Garcia-Diaz, M.2
Bebenek, K.3
Pedersen, L.C.4
Kunkel, T.A.5
Blanco, L.6
-
116
-
-
35748946285
-
Human DNA polymerase lambda is a proficient extender of primer ends paired to 7,8-dihydro-8-oxoguanine
-
Picher, A.J.; Blanco, L. Human DNA polymerase lambda is a proficient extender of primer ends paired to 7,8-dihydro-8-oxoguanine. DNA Repair (Amst) 2007, 6, 1749-56.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 1749-1756
-
-
Picher, A.J.1
Blanco, L.2
-
117
-
-
0347683431
-
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts
-
Lee, J.W.; Blanco, L.; Zhou, T.; Garcia-Diaz, M.; Bebenek, K.; Kunkel, T.A.; Wang, Z.; Povirk, L.F. Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. J. Biol. Chem. 2004, 279, 805-11.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 805-811
-
-
Lee, J.W.1
Blanco, L.2
Zhou, T.3
Garcia-Diaz, M.4
Bebenek, K.5
Kunkel, T.A.6
Wang, Z.7
Povirk, L.F.8
-
118
-
-
38849173186
-
Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells
-
Vermeulen, C.; Bertocci, B.; Begg, A.C.; Vens, C. Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells. Radiat. Res. 2007, 168, 683-8.
-
(2007)
Radiat. Res
, vol.168
, pp. 683-688
-
-
Vermeulen, C.1
Bertocci, B.2
Begg, A.C.3
Vens, C.4
-
119
-
-
17944397758
-
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: Possible implication for the pathogenesis of immotile cilia syndrome
-
Kobayashi, Y.; Watanabe, M.; Okada, Y.; Sawa, H.; Takai, H.; Nakanishi, M.; Kawase, Y.; Suzuki, H.; Nagashima, K.; Ikeda, K.; Motoyama, N. Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: Possible implication for the pathogenesis of immotile cilia syndrome. Mol. Cell Biol. 2002, 22, 2769-76.
-
(2002)
Mol. Cell Biol
, vol.22
, pp. 2769-2776
-
-
Kobayashi, Y.1
Watanabe, M.2
Okada, Y.3
Sawa, H.4
Takai, H.5
Nakanishi, M.6
Kawase, Y.7
Suzuki, H.8
Nagashima, K.9
Ikeda, K.10
Motoyama, N.11
-
120
-
-
0037090311
-
DNA polymerases mu and lambda are dispensable for Ig gene hypermutation
-
Bertocci, B.; De Smet, A.; Flatter, E.; Dahan, A.; Bories, J.C.; Landreau, C.; Weill, J.C.; Reynaud, C.A. Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation. J. Immunol. 2002, 168, 3702-6.
-
(2002)
J. Immunol
, vol.168
, pp. 3702-3706
-
-
Bertocci, B.1
De Smet, A.2
Flatter, E.3
Dahan, A.4
Bories, J.C.5
Landreau, C.6
Weill, J.C.7
Reynaud8
Cutting edge, C.A.9
-
121
-
-
34547135486
-
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells
-
Capp, J.P.; Boudsocq, F.; Besnard, A.G.; Lopez, B.S.; Cazaux, C.; Hoffmann, J.S.; Canitrot, Y. Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Nucleic Acids Res. 2007, 35, 3551-60.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 3551-3560
-
-
Capp, J.P.1
Boudsocq, F.2
Besnard, A.G.3
Lopez, B.S.4
Cazaux, C.5
Hoffmann, J.S.6
Canitrot, Y.7
-
122
-
-
33750041949
-
A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis
-
Juarez, R.; Ruiz, J.F.; Nick McElhinny, S.A.; Ramsden, D.; Blanco, L. A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. Nucleic Acids Res. 2006, 34, 4572-82.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4572-4582
-
-
Juarez, R.1
Ruiz, J.F.2
Nick McElhinny, S.A.3
Ramsden, D.4
Blanco, L.5
-
123
-
-
0035158355
-
Highly frequent frameshift DNA synthesis by human DNA polymerase mu
-
Zhang, Y.; Wu, X.; Yuan, F.; Xie, Z.; Wang, Z. Highly frequent frameshift DNA synthesis by human DNA polymerase mu. Mol. Cell Biol. 2001, 21, 7995-8006.
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 7995-8006
-
-
Zhang, Y.1
Wu, X.2
Yuan, F.3
Xie, Z.4
Wang, Z.5
-
124
-
-
0037113885
-
Lesion bypass activities of human DNA polymerase mu
-
Zhang, Y.; Wu, X.; Guo, D.; Rechkoblit, O.; Taylor, J.S.; Geacintov, N.E.; Wang, Z. Lesion bypass activities of human DNA polymerase mu. J. Biol. Chem. 2002, 277, 44582-7.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 44582-44587
-
-
Zhang, Y.1
Wu, X.2
Guo, D.3
Rechkoblit, O.4
Taylor, J.S.5
Geacintov, N.E.6
Wang, Z.7
-
125
-
-
7244255742
-
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu
-
Roettger, M.P.; Fiala, K.A.; Sompalli, S.; Dong, Y.; Suo, Z. Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. Biochemistry 2004, 43, 13827-38.
-
(2004)
Biochemistry
, vol.43
, pp. 13827-13838
-
-
Roettger, M.P.1
Fiala, K.A.2
Sompalli, S.3
Dong, Y.4
Suo, Z.5
-
126
-
-
44349155971
-
End-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joining
-
Davis, B.J.; Havener, J.M.; Ramsden, D.A. End-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joining. Nucleic Acids Res. 2008, 36, 3085-94.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 3085-3094
-
-
Davis, B.J.1
Havener, J.M.2
Ramsden, D.A.3
-
127
-
-
0036293744
-
Association of DNA polymerase mu (pol mu) with Ku and ligase IV: Role for pol mu in end-joining double-strand break repair
-
Mahajan, K.N.; Nick McElhinny, S.A.; Mitchell, B.S.; Ramsden, D.A. Association of DNA polymerase mu (pol mu) with Ku and ligase IV: Role for pol mu in end-joining double-strand break repair. Mol. Cell Biol. 2002, 22, 5194-202.
-
(2002)
Mol. Cell Biol
, vol.22
, pp. 5194-5202
-
-
Mahajan, K.N.1
Nick McElhinny, S.A.2
Mitchell, B.S.3
Ramsden, D.A.4
-
128
-
-
35648951054
-
Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining
-
DeRose, E.F.; Clarkson, M.W.; Gilmore, S.A.; Galban, C.J.; Tripathy, A.; Havener, J.M.; Mueller, G.A.; Ramsden, D.A.; London, R.E.; Lee, A.L. Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Biochemistry 2007, 46, 12100-10.
-
(2007)
Biochemistry
, vol.46
, pp. 12100-12110
-
-
DeRose, E.F.1
Clarkson, M.W.2
Gilmore, S.A.3
Galban, C.J.4
Tripathy, A.5
Havener, J.M.6
Mueller, G.A.7
Ramsden, D.A.8
London, R.E.9
Lee, A.L.10
-
129
-
-
33846075032
-
Structural insight into the substrate specificity of DNA Polymerase mu
-
Moon, A.F.; Garcia-Diaz, M.; Bebenek, K.; Davis, B.J.; Zhong, X.; Ramsden, D.A.; Kunkel, T.A.; Pedersen, L.C. Structural insight into the substrate specificity of DNA Polymerase mu. Nat. Struct. Mol. Biol. 2007, 14, 45-53.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 45-53
-
-
Moon, A.F.1
Garcia-Diaz, M.2
Bebenek, K.3
Davis, B.J.4
Zhong, X.5
Ramsden, D.A.6
Kunkel, T.A.7
Pedersen, L.C.8
-
130
-
-
0041931065
-
Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu
-
Bertocci, B.; De Smet, A.; Berek, C.; Weill, J.C.; Reynaud, C.A. Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu. Immunity 2003, 19, 203-11.
-
(2003)
Immunity
, vol.19
, pp. 203-211
-
-
Bertocci, B.1
De Smet, A.2
Berek, C.3
Weill, J.C.4
Reynaud, C.A.5
-
131
-
-
33745997776
-
Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo
-
Bertocci, B.; De Smet, A.; Weill, J.C.; Reynaud, C.A. Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo. Immunity 2006, 25, 31-41.
-
(2006)
Immunity
, vol.25
, pp. 31-41
-
-
Bertocci, B.1
De Smet, A.2
Weill, J.C.3
Reynaud, C.A.4
-
132
-
-
0033548231
-
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta
-
Johnson, R.E.; Prakash, S.; Prakash, L. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 1999, 283, 1001-4.
-
(1999)
Science
, vol.283
, pp. 1001-1004
-
-
Johnson, R.E.1
Prakash, S.2
Prakash, L.3
-
133
-
-
0034847259
-
Structure of the catalytic core of S. cerevisiae DNA polymerase eta: Implications for translesion DNA synthesis
-
Trincao, J.; Johnson, R.E.; Escalante, C.R.; Prakash, S.; Prakash, L.; Aggarwal, A.K. Structure of the catalytic core of S. cerevisiae DNA polymerase eta: Implications for translesion DNA synthesis. Mol. Cell 2001, 8, 417-26.
-
(2001)
Mol. Cell
, vol.8
, pp. 417-426
-
-
Trincao, J.1
Johnson, R.E.2
Escalante, C.R.3
Prakash, S.4
Prakash, L.5
Aggarwal, A.K.6
-
134
-
-
36048931023
-
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta
-
Alt, A.; Lammens, K.; Chiocchini, C.; Lammens, A.; Pieck, J.C.; Kuch, D.; Hopfner, K.P.; Carell, T. Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta. Science 2007, 318, 967-70.
-
(2007)
Science
, vol.318
, pp. 967-970
-
-
Alt, A.1
Lammens, K.2
Chiocchini, C.3
Lammens, A.4
Pieck, J.C.5
Kuch, D.6
Hopfner, K.P.7
Carell, T.8
-
135
-
-
0037773539
-
Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta
-
Washington, M.T.; Helquist, S.A.; Kool, E.T.; Prakash, L.; Prakash, S. Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta. Mol. Cell Biol. 2003, 23, 5107-12.
-
(2003)
Mol. Cell Biol
, vol.23
, pp. 5107-5112
-
-
Washington, M.T.1
Helquist, S.A.2
Kool, E.T.3
Prakash, L.4
Prakash, S.5
-
136
-
-
23344450921
-
Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa
-
Wolfle, W.T.; Washington, M.T.; Kool, E.T.; Spratt, T.E.; Helquist, S.A.; Prakash, L.; Prakash, S. Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Mol. Cell Biol. 2005, 25, 7137-43.
-
(2005)
Mol. Cell Biol
, vol.25
, pp. 7137-7143
-
-
Wolfle, W.T.1
Washington, M.T.2
Kool, E.T.3
Spratt, T.E.4
Helquist, S.A.5
Prakash, L.6
Prakash, S.7
-
137
-
-
33747765185
-
Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota
-
Johnson, R.E.; Haracska, L.; Prakash, L.; Prakash, S. Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota. Mol. Cell Biol. 2006, 26, 6435-41.
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 6435-6441
-
-
Johnson, R.E.1
Haracska, L.2
Prakash, L.3
Prakash, S.4
-
138
-
-
1542287220
-
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity
-
McCulloch, S.D.; Kokoska, R.J.; Masutani, C.; Iwai, S.; Hanaoka, F.; Kunkel, T.A. Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Nature 2004, 428, 97-100.
-
(2004)
Nature
, vol.428
, pp. 97-100
-
-
McCulloch, S.D.1
Kokoska, R.J.2
Masutani, C.3
Iwai, S.4
Hanaoka, F.5
Kunkel, T.A.6
-
139
-
-
0242663959
-
The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme
-
Washington, M.T.; Johnson, R.E.; Prakash, L.; Prakash, S. The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol. Cell Biol. 2003, 23, 8316-22.
-
(2003)
Mol. Cell Biol
, vol.23
, pp. 8316-8322
-
-
Washington, M.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
-
140
-
-
0033538470
-
hRAD30 mutations in the variant form of xeroderma pigmentosum
-
Johnson, R.E.; Kondratick, C.M.; Prakash, S.; Prakash, L. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science 1999, 285, 263-5.
-
(1999)
Science
, vol.285
, pp. 263-265
-
-
Johnson, R.E.1
Kondratick, C.M.2
Prakash, S.3
Prakash, L.4
-
141
-
-
0033578040
-
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta
-
Masutani, C.; Kusumoto, R.; Yamada, A.; Dohmae, N.; Yokoi, M.; Yuasa, M.; Araki, M.; Iwai, S.; Takio, K.; Hanaoka, F. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature 1999, 399, 700-4.
-
(1999)
Nature
, vol.399
, pp. 700-704
-
-
Masutani, C.1
Kusumoto, R.2
Yamada, A.3
Dohmae, N.4
Yokoi, M.5
Yuasa, M.6
Araki, M.7
Iwai, S.8
Takio, K.9
Hanaoka, F.10
-
142
-
-
33749602964
-
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota
-
Ohkumo, T.; Kondo, Y.; Yokoi, M.; Tsukamoto, T.; Yamada, A.; Sugimoto, T.; Kanao, R.; Higashi, Y.; Kondoh, H.; Tatematsu, M.; Masutani, C.; Hanaoka, F. UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Mol. Cell Biol. 2006, 26, 7696-706.
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 7696-7706
-
-
Ohkumo, T.1
Kondo, Y.2
Yokoi, M.3
Tsukamoto, T.4
Yamada, A.5
Sugimoto, T.6
Kanao, R.7
Higashi, Y.8
Kondoh, H.9
Tatematsu, M.10
Masutani, C.11
Hanaoka, F.12
-
143
-
-
31544443220
-
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice
-
Lin, Q.; Clark, A.B.; McCulloch, S.D.; Yuan, T.; Bronson, R.T.; Kunkel, T.A.; Kucherlapati, R. Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Cancer Res. 2006, 66, 87-94.
-
(2006)
Cancer Res
, vol.66
, pp. 87-94
-
-
Lin, Q.1
Clark, A.B.2
McCulloch, S.D.3
Yuan, T.4
Bronson, R.T.5
Kunkel, T.A.6
Kucherlapati, R.7
-
144
-
-
47349099501
-
Xeroderma pigmentosum-variant patients from America, Europe, and Asia
-
Inui, H.; Oh, K.S.; Nadem, C.; Ueda, T.; Khan, S.G.; Metin, A.; Gozukara, E.; Emmert, S.; Slor, H.; Busch, D.B.; Baker, C.C.; DiGiovanna, J.J.; Tamura, D.; Seitz, C.S.; Gratchev, A.; Wu, W.H.; Chung, K.Y.; Cbung, H.J.; Azizi, E.; Woodgate, R.; Schneider, T.D.;Kraemer, K.H. Xeroderma pigmentosum-variant patients from America, Europe, and Asia. J. Invest. Dermatol. 2008, 128, 2055-68.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 2055-2068
-
-
Inui, H.1
Oh, K.S.2
Nadem, C.3
Ueda, T.4
Khan, S.G.5
Metin, A.6
Gozukara, E.7
Emmert, S.8
Slor, H.9
Busch, D.B.10
Baker, C.C.11
DiGiovanna, J.J.12
Tamura, D.13
Seitz, C.S.14
Gratchev, A.15
Wu, W.H.16
Chung, K.Y.17
Cbung, H.J.18
Azizi, E.19
Woodgate, R.20
Schneider, T.D.21
Kraemer, K.H.22
more..
-
145
-
-
18244402410
-
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients
-
Broughton, B.C.; Cordonnier, A.; Kleijer, W.J.; Jaspers, N.G.; Fawcett, H.; Raams, A.; Garritsen, V.H.; Stary, A.; Avril, M.F.; Boudsocq, F.; Masutani, C.; Hansoka, F.; Fuchs, R.P.; Sarasin, A.; Lehmann,A.R. Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Proc. Natl. Acad. Sci. USA 2002, 99, 815-20.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 815-820
-
-
Broughton, B.C.1
Cordonnier, A.2
Kleijer, W.J.3
Jaspers, N.G.4
Fawcett, H.5
Raams, A.6
Garritsen, V.H.7
Stary, A.8
Avril, M.F.9
Boudsocq, F.10
Masutani, C.11
Hansoka, F.12
Fuchs, R.P.13
Sarasin, A.14
Lehmann, A.R.15
-
146
-
-
34250690390
-
Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type
-
Tanioka, M.; Masaki, T.; Ono, R.; Nagano, T.; Otoshi-Honda, E.; Matsumura, Y.; Takigawa, M.; Inui, H.; Miyachi, Y.; Moriwaki, S.; Nishigori, C. Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type. J. Invest. Dermatol. 2007, 127, 1745-51.
-
(1745)
J. Invest. Dermatol
, vol.2007
, pp. 127
-
-
Tanioka, M.1
Masaki, T.2
Ono, R.3
Nagano, T.4
Otoshi-Honda, E.5
Matsumura, Y.6
Takigawa, M.7
Inui, H.8
Miyachi, Y.9
Moriwaki, S.10
Nishigori, C.11
-
147
-
-
0035896008
-
Kunkel, TA 5′-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro
-
Bebenek, K.; Tissier, A.; Frank E.G.; McDonald, J.P.; Prasad, R.; Wilson, S.H.; Woodgate, R.; Kunkel, TA 5′-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro. Science 2001, 291, 21569.
-
(2001)
Science
, vol.291
, pp. 21569
-
-
Bebenek, K.1
Tissier, A.2
Frank, E.G.3
McDonald, J.P.4
Prasad, R.5
Wilson, S.H.6
Woodgate, R.7
-
148
-
-
0042031052
-
Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis
-
Prasad, R.; Bebenek, K.; Hou, E.; Shock, D.D.; Beard, W.A.; Woodgate, R.; Kunkel, TA; Wilson, S.H. Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. J. Biol. Chem. 2003, 278, 29649-54
-
(2003)
J. Biol. Chem
, vol.278
, pp. 29649-29654
-
-
Prasad, R.1
Bebenek, K.2
Hou, E.3
Shock, D.D.4
Beard, W.A.5
Woodgate, R.6
Kunkel, T.A.7
Wilson, S.H.8
-
149
-
-
0034738983
-
Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions
-
Johnson, R.E.; Washington, M.T.; Haracska, L.; Prakash, S.; Prakash, L. Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Nature 2000, 406, 1015-9.
-
(2000)
Nature
, vol.406
, pp. 1015-1019
-
-
Johnson, R.E.1
Washington, M.T.2
Haracska, L.3
Prakash, S.4
Prakash, L.5
-
150
-
-
0034214838
-
-
Tissier, A.; McDonald, J.P.; Frank, E.G.; Woodgate, R. poliota, a remarkably error-prone human DNA polymerase. Genes. Dev. 2000, 14, 1642-50.
-
Tissier, A.; McDonald, J.P.; Frank, E.G.; Woodgate, R. poliota, a remarkably error-prone human DNA polymerase. Genes. Dev. 2000, 14, 1642-50.
-
-
-
-
151
-
-
0033830464
-
Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota
-
Zhang, Y.; Yuan, F.; Wu, X; Wang, Z. Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota. Mol, Cell Biol. 2000, 20, 7099-108.
-
(2000)
Mol, Cell Biol
, vol.20
, pp. 7099-7108
-
-
Zhang, Y.1
Yuan, F.2
Wu, X.3
Wang, Z.4
-
152
-
-
3142674288
-
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing
-
Nair, D.T.; Johnson, R.E.; Prakash, S.; Prakash, L.; Aggarwal, A.K. Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature 2004, 430, 377-80.
-
(2004)
Nature
, vol.430
, pp. 377-380
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, S.3
Prakash, L.4
Aggarwal, A.K.5
-
153
-
-
33646492746
-
An incoming nucleotideimposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site
-
Nair, D.T.; Johnson, R.E.; Prakash, L.; Prakash, S.; Aggarwal, A.K. An incoming nucleotideimposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure 2006, 14, 749-55.
-
(2006)
Structure
, vol.14
, pp. 749-755
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
154
-
-
34248195087
-
Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations
-
Wang, Y.; Woodgate, R.; McManus, T.P.; Mead, S.; McCormick, J.J.; Maher, V.M. Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations. Cancer Res. 2007, 67, 3018-26.
-
(2007)
Cancer Res
, vol.67
, pp. 3018-3026
-
-
Wang, Y.1
Woodgate, R.2
McManus, T.P.3
Mead, S.4
McCormick, J.J.5
Maher, V.M.6
-
155
-
-
0042422042
-
129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation
-
McDonald, J.P.; Frank, E.G.; Plosky, B.S.; Rogozin, I.B.; Masutani,C.; Hanaoka, F.; Woodgate, R.; Gearhart, P.J. 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation. J. Exp. Med. 2003, 198, 635-43.
-
(2003)
J. Exp. Med
, vol.198
, pp. 635-643
-
-
McDonald, J.P.1
Frank, E.G.2
Plosky, B.S.3
Rogozin, I.B.4
Masutani, C.5
Hanaoka, F.6
Woodgate, R.7
Gearhart, P.J.8
-
156
-
-
33845287261
-
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer
-
Dumstorf, C.A.; Clark A.B.; Lin, Q.; Kissling, G.E.; Yuan, T.; Kucherlapati, R.; McGregor, W.G.; Kunkel, T.A. Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Proc. Natl. Acad. Sci. USA 2006, 103, 18083-8.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18083-18088
-
-
Dumstorf, C.A.1
Clark, A.B.2
Lin, Q.3
Kissling, G.E.4
Yuan, T.5
Kucherlapati, R.6
McGregor, W.G.7
Kunkel, T.A.8
-
157
-
-
0034671730
-
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene
-
Ohashi, E.; Benenek, K.; Matsuda, T.; Feaver, W.J.; Gerlach, V.L.; Friedberg, E.C.; Ohmori, H.; Kunkel, T.A. Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. J. Biol. Chem. 2000, 275, 39678-84.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 39678-39684
-
-
Ohashi, E.1
Benenek, K.2
Matsuda, T.3
Feaver, W.J.4
Gerlach, V.L.5
Friedberg, E.C.6
Ohmori, H.7
Kunkel, T.A.8
-
158
-
-
0034327552
-
Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelity
-
Zhang, Y.; Yuan, F.; Xin, H.; Wu, X; Rajpal, D.K.; Yang, D.; Wang, Z. Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelity. Nucleic Acids Res. 2000, 28, 4147-56
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 4147-4156
-
-
Zhang, Y.1
Yuan, F.2
Xin, H.3
Wu, X.4
Rajpal, D.K.5
Yang, D.6
Wang, Z.7
-
159
-
-
0037020269
-
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides
-
Fischhaber,P.L.; Gerlach, V.L.; Feaver, W.J.; Hatahet, Z.; Wallace, S.S.; Friedberg, E.C. Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. J. Biol. Chem. 2002, 277, 37604-11.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 37604-37611
-
-
Fischhaber, P.L.1
Gerlach, V.L.2
Feaver, W.J.3
Hatahet, Z.4
Wallace, S.S.5
Friedberg, E.C.6
-
160
-
-
0034327408
-
-
Zhang, Y.; Yuan, F.; Wu, X; Wang, M.; Rechkoblit, O.; Taylor, J.S.; Geacintov, N.E.; Wang, Z. Error-fre and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucleic Acids Res. 2000, 28, 4138-46.
-
Zhang, Y.; Yuan, F.; Wu, X; Wang, M.; Rechkoblit, O.; Taylor, J.S.; Geacintov, N.E.; Wang, Z. Error-fre and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucleic Acids Res. 2000, 28, 4138-46.
-
-
-
-
161
-
-
33847208855
-
Human DNA polymerase kappa encircles DNA: Implications for mismatch extension and lesion bypass
-
Lone, S.; Townson, SA; Uljon, S.N.; Johnson, R.E.; Brahma, A.; Nair, D.T.; Prakash, S.; Prakash, L.; Aggarwal, A.K. Human DNA polymerase kappa encircles DNA: Implications for mismatch extension and lesion bypass. Mol, Cell 2007, 25, 601-14.
-
(2007)
Mol, Cell
, vol.25
, pp. 601-614
-
-
Lone, S.1
Townson, S.A.2
Uljon, S.N.3
Johnson, R.E.4
Brahma, A.5
Nair, D.T.6
Prakash, S.7
Prakash, L.8
Aggarwal, A.K.9
-
162
-
-
33744789415
-
The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair
-
Ogi, T.; Lehmann, A.R. The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair. Natl. Cell Biol. 2006, 8, 640-2.
-
(2006)
Natl. Cell Biol
, vol.8
, pp. 640-642
-
-
Ogi, T.1
Lehmann, A.R.2
-
163
-
-
19944426305
-
-
Bavoux, C.; Leopoldino, A.M.; Bergoglio, V.; J, O. W.; Ogi, T.; Bieth, A.; Judde, J.G.; Pena, S.D.; Poupon, M.F.; Helleday, T.; Tagawa, M.; Machado, C.; Hoffmann, J.S.; Cazaux, C. Upregulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cancer Res. 2005, 65, 325-30.
-
Bavoux, C.; Leopoldino, A.M.; Bergoglio, V.; J, O. W.; Ogi, T.; Bieth, A.; Judde, J.G.; Pena, S.D.; Poupon, M.F.; Helleday, T.; Tagawa, M.; Machado, C.; Hoffmann, J.S.; Cazaux, C. Upregulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cancer Res. 2005, 65, 325-30.
-
-
-
-
164
-
-
34249021158
-
Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer
-
Lemee, F.; Bavoux, C.; Pillaire, M.J.; Bieth, A.; Machado, C.R.; Pena, S.D.; Guintbaud, R.; Selves, J.; Hoffmann, J.S.; Cazaux, C. Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Oncogene 2007, 26, 3387-94.
-
(2007)
Oncogene
, vol.26
, pp. 3387-3394
-
-
Lemee, F.1
Bavoux, C.2
Pillaire, M.J.3
Bieth, A.4
Machado, C.R.5
Pena, S.D.6
Guintbaud, R.7
Selves, J.8
Hoffmann, J.S.9
Cazaux, C.10
-
165
-
-
0037180343
-
Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene
-
Ogi, T.; Shinkai, Y.; Tanaka, K.; Ohmori, H. Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene. Proc. Natl. Acad. Sci. USA 2002, 99, 15548-53.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15548-15553
-
-
Ogi, T.1
Shinkai, Y.2
Tanaka, K.3
Ohmori, H.4
-
166
-
-
0037403827
-
The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene
-
Shimizu, T.; Shinkai, Y.; Ogi, T.; Ohmori, H.; Azuma, T. The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene. Immunol. Lett. 2003, 86, 265-70.
-
(2003)
Immunol. Lett
, vol.86
, pp. 265-270
-
-
Shimizu, T.1
Shinkai, Y.2
Ogi, T.3
Ohmori, H.4
Azuma, T.5
-
167
-
-
0032994152
-
-
Lin, W.; Wu, X; Wang, Z. A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans. Mutat Res. 1999, 433, 89-98.
-
Lin, W.; Wu, X; Wang, Z. A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans. Mutat Res. 1999, 433, 89-98.
-
-
-
-
168
-
-
0029787108
-
Deoxycytidyl transferase activity of yeast REV1 protein
-
Nelson, J.R.; Lawrence, C.W.; Hinkle, D.C. Deoxycytidyl transferase activity of yeast REV1 protein. Nature 1996, 382, 729-31.
-
(1996)
Nature
, vol.382
, pp. 729-731
-
-
Nelson, J.R.1
Lawrence, C.W.2
Hinkle, D.C.3
-
169
-
-
53049095093
-
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1
-
Choi, J.Y.; Guengerich, F.P. Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. J. Biol. Chem. 2008,
-
(2008)
J. Biol. Chem
-
-
Choi, J.Y.1
Guengerich, F.P.2
-
170
-
-
0345732688
-
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis
-
Guo, C.; Fischhaber, P.L.; Luk-Paszyc, M.J.; Masuda, Y.; Zhou, J.; Kamiya, K.; Kisker, C.; Friedberg, E.C. Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J. 2003, 22, 6621-30.
-
(2003)
EMBO J
, vol.22
, pp. 6621-6630
-
-
Guo, C.1
Fischhaber, P.L.2
Luk-Paszyc, M.J.3
Masuda, Y.4
Zhou, J.5
Kamiya, K.6
Kisker, C.7
Friedberg, E.C.8
-
171
-
-
48149104225
-
Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance
-
D'Souza, S.; Waters, L.S.; Walker, G.C. Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance. DNA Rqwir. (Amst) 2008, 7, 1455-70.
-
(2008)
DNA Rqwir. (Amst)
, vol.7
, pp. 1455-1470
-
-
D'Souza, S.1
Waters, L.S.2
Walker, G.C.3
-
172
-
-
27144521116
-
Complex formation of yeast Rev1 and Rev7 proteins: A novel role for the polymerase-associated domain
-
Acharya, N.; Haracska, L.; Johnson, R.E.; Unk, L; Prakash, S.; Prakash, L. Complex formation of yeast Rev1 and Rev7 proteins: A novel role for the polymerase-associated domain. Mol, Cell Biol. 2005, 25, 9734-40.
-
(2005)
Mol, Cell Biol
, vol.25
, pp. 9734-9740
-
-
Acharya, N.1
Haracska, L.2
Johnson, R.E.3
Unk, L.4
Prakash, S.5
Prakash, L.6
-
173
-
-
3542992656
-
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta
-
Washington, M.T.; Minko, I.G.; Johnson, R.E.; Haracska, L.; Harris, T.M.; Lloyd, R.S.; Prakash, S.; Prakash, L. Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Mol. Cell Biol. 2004, 24, 6900-6.
-
(2004)
Mol. Cell Biol
, vol.24
, pp. 6900-6906
-
-
Washington, M.T.1
Minko, I.G.2
Johnson, R.E.3
Haracska, L.4
Harris, T.M.5
Lloyd, R.S.6
Prakash, S.7
Prakash, L.8
-
174
-
-
25844440534
-
Rev1 employs a novel mechanism of DNA synthesis using a protein template
-
Nair, D.T.; Johnson, R.E.; Prakash, L.; Prakash, S.; Aggarwal, A.K. Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science 2005, 309, 2219-22.
-
(2005)
Science
, vol.309
, pp. 2219-2222
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
175
-
-
38949182319
-
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase
-
Nair, D.T.; Johnson, R.E.; Prakash, L.; Prakash, S.; Aggarwal, A.K. Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Structure 2008, 16, 239-45.
-
(2008)
Structure
, vol.16
, pp. 239-245
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
176
-
-
44449153036
-
REV1 genetic variants associated with the risk of cervical carcinoma
-
He, X.; Ye, F.; Zhang, J.; Cheng, Q.; Shen, J.; Chen, H. REV1 genetic variants associated with the risk of cervical carcinoma. Eur. J. Epidemiol. 2008, 23, 403-9.
-
(2008)
Eur. J. Epidemiol
, vol.23
, pp. 403-409
-
-
He, X.1
Ye, F.2
Zhang, J.3
Cheng, Q.4
Shen, J.5
Chen, H.6
-
177
-
-
0242353199
-
Unique error signature of the four-subunit yeast DNA polymerase epsilon
-
Shcherbakova, P.V.; Pavlov, Y.I.; Chilkova, O.; Rogozin, I.B.; Johansson, E.; Kunkel, TA Unique error signature of the four-subunit yeast DNA polymerase epsilon. J. Biol. Chem. 2003, 278, 43770-80.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 43770-43780
-
-
Shcherbakova, P.V.1
Pavlov, Y.I.2
Chilkova, O.3
Rogozin, I.B.4
Johansson, E.5
Kunkel, T.A.6
-
178
-
-
33748941448
-
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins
-
Zhong, X.; Garg, P.; Stith, C.M.; Nick McElhinny, S.A.; Kissling, G.E.; Burgers, P.M.; Kunkel, TA. The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Nucleic Acids Res. 2006, 34, 4731-42.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4731-4742
-
-
Zhong, X.1
Garg, P.2
Stith, C.M.3
Nick McElhinny, S.A.4
Kissling, G.E.5
Burgers, P.M.6
Kunkel, T.A.7
-
179
-
-
0344527720
-
The fidelity of DNA polymerase beta during distributive and processive DNA synthesis
-
Osheroff, W.P.; Jung, H.K.; Beard, W.A.; Wilson, S.H.; Kunkel, T.A. The fidelity of DNA polymerase beta during distributive and processive DNA synthesis. J. Biol. Chem. 1999, 274, 3642-50.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 3642-3650
-
-
Osheroff, W.P.1
Jung, H.K.2
Beard, W.A.3
Wilson, S.H.4
Kunkel, T.A.5
-
180
-
-
0141483284
-
The frameshift infidelity of human DNA polymerase lambda. Implications for function
-
Bebenek, K.; Garcia-Diaz, M.; Blanco, L.; Kunkel, T.A. The frameshift infidelity of human DNA polymerase lambda. Implications for function. J. Biol. Chem. 2003, 278, 34685-90.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 34685-34690
-
-
Bebenek, K.1
Garcia-Diaz, M.2
Blanco, L.3
Kunkel, T.A.4
-
181
-
-
0037461342
-
Mutations of ANT1, Twinkle, and POLG1 in sporadic progressive external ophthalmoplegia (PEO)
-
Agostino, A.; Valletta, L.; Chinnery, P.F.; Ferrari, G.; Carrara, F.; Taylor, R.W.; Schaefer, A.M.; Turnbull, D.M.; Tiranti, V.; Zeviani, M. Mutations of ANT1, Twinkle, and POLG1 in sporadic progressive external ophthalmoplegia (PEO). Neurology 2003, 60, 1354-6
-
(2003)
Neurology
, vol.60
, pp. 1354-1356
-
-
Agostino, A.1
Valletta, L.2
Chinnery, P.F.3
Ferrari, G.4
Carrara, F.5
Taylor, R.W.6
Schaefer, A.M.7
Turnbull, D.M.8
Tiranti, V.9
Zeviani, M.10
-
182
-
-
4444316397
-
Sequence analysis of familial PEO shows additional mutations associated with the 752C -> T and 3527C->T changes in the POLG1 gene
-
Lamantea, E.; Zeviani, M. Sequence analysis of familial PEO shows additional mutations associated with the 752C -> T and 3527C->T changes in the POLG1 gene. Ann. Neurol. 2004, 56, 454-5.
-
(2004)
Ann. Neurol
, vol.56
, pp. 454-455
-
-
Lamantea, E.1
Zeviani, M.2
-
183
-
-
0036327184
-
Mutations of mitochondrial DNA polymerase gammaA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia
-
Lamantea, E.; Tiranti, V.; Bordoni, A.; Toscano, A.; Bono, F.; Servidei, S.; Papadimitriou, A.; Spelbrink, H.; Silvestri, L.; Casari, G.; Comi, G.P.; Zeviani, M. Mutations of mitochondrial DNA polymerase gammaA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia. Ann. Neurol. 2002, 52, 211-9.
-
(2002)
Ann. Neurol
, vol.52
, pp. 211-219
-
-
Lamantea, E.1
Tiranti, V.2
Bordoni, A.3
Toscano, A.4
Bono, F.5
Servidei, S.6
Papadimitriou, A.7
Spelbrink, H.8
Silvestri, L.9
Casari, G.10
Comi, G.P.11
Zeviani, M.12
-
184
-
-
0043027711
-
Novel POLG mutations in progressive external ophthalmoplegia mimicking mitochondrial neurogastro-intestinal encephalomyopathy
-
Van Goethem, G.; Schwartz, M.; Lofgren, A.; Dermaut, B.; Van Broeckhoven, C.; Vissing, J. Novel POLG mutations in progressive external ophthalmoplegia mimicking mitochondrial neurogastro-intestinal encephalomyopathy. Eur. J. Hum. Genet. 2003, 11, 547-9.
-
(2003)
Eur. J. Hum. Genet
, vol.11
, pp. 547-549
-
-
Van Goethem, G.1
Schwartz, M.2
Lofgren, A.3
Dermaut, B.4
Van Broeckhoven, C.5
Vissing, J.6
-
185
-
-
4444276204
-
POLG mutations in sporadic mitochondrial disorders with multiple mtDNA deletions
-
Di Fonzo, A.; Bordoni, A.; Crimi, M.; Sara, G.; Del Bo, R.; Bresolin, N.; Comi, G.P. POLG mutations in sporadic mitochondrial disorders with multiple mtDNA deletions. Hum. Mutat. 2003, 22, 498-9.
-
(2003)
Hum. Mutat
, vol.22
, pp. 498-499
-
-
Di Fonzo, A.1
Bordoni, A.2
Crimi, M.3
Sara, G.4
Del Bo, R.5
Bresolin, N.6
Comi, G.P.7
-
186
-
-
0141993876
-
Remarkable infidelity of polymerase gammaA associated with mutations in POLG1 exonuclease domain
-
Del Bo, R.; Bordoni, A.; Sciacco, M.; Di Fonzo, A.; Galbiati, S.; Crimi, M.; Bresolin, N.; Comi, G.P. Remarkable infidelity of polymerase gammaA associated with mutations in POLG1 exonuclease domain. Neurology 2003, 61, 903-8.
-
(2003)
Neurology
, vol.61
, pp. 903-908
-
-
Del Bo, R.1
Bordoni, A.2
Sciacco, M.3
Di Fonzo, A.4
Galbiati, S.5
Crimi, M.6
Bresolin, N.7
Comi, G.P.8
-
187
-
-
45449101303
-
Two novel POLG1 mutations in a patient with progressive external ophthalmoplegia, levodopa-responsive pseudo-orthostatic tremor and parkinsonism
-
Invernizzi, F.; Varanese, S.; Thomas, A.; Carrara, F.; Onofrj, M.; Zeviani, M. Two novel POLG1 mutations in a patient with progressive external ophthalmoplegia, levodopa-responsive pseudo-orthostatic tremor and parkinsonism. Neuromuscul. Disord. 2008, 18, 460-4.
-
(2008)
Neuromuscul. Disord
, vol.18
, pp. 460-464
-
-
Invernizzi, F.1
Varanese, S.2
Thomas, A.3
Carrara, F.4
Onofrj, M.5
Zeviani, M.6
-
188
-
-
34247122280
-
Mutation of the linker region of the polymerase gamma-1 (POLG1) gene associated with progressive external ophthalmoplegia and Parkinsonism
-
Hudson, G.; Schaefer, A.M.; Taylor, R.W.; Tiangyou, W.; Gibson, A.; Venables, G.; Griffiths, P.; Burn, D.J.; Turnbull, D.M.; Chinnery, P.F. Mutation of the linker region of the polymerase gamma-1 (POLG1) gene associated with progressive external ophthalmoplegia and Parkinsonism. Arch. Neurol. 2007, 64, 553-7.
-
(2007)
Arch. Neurol
, vol.64
, pp. 553-557
-
-
Hudson, G.1
Schaefer, A.M.2
Taylor, R.W.3
Tiangyou, W.4
Gibson, A.5
Venables, G.6
Griffiths, P.7
Burn, D.J.8
Turnbull, D.M.9
Chinnery, P.F.10
-
189
-
-
0037306061
-
Recessive POLG mutations presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia
-
Van Goethem, G.; Martin, J.J.; Dermaut, B.; Lofgren, A.; Wibail, A.; Ververken, D.; Tack, P.; Dehaene, I.; Van Zandijcke, M.; Moonen, M.; Ceuterick, C.; De Jonghe, P.; Van Broeckhoven, C. Recessive POLG mutations presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia. Neuromuscul. Disord. 2003, 13, 133-42.
-
(2003)
Neuromuscul. Disord
, vol.13
, pp. 133-142
-
-
Van Goethem, G.1
Martin, J.J.2
Dermaut, B.3
Lofgren, A.4
Wibail, A.5
Ververken, D.6
Tack, P.7
Dehaene, I.8
Van Zandijcke, M.9
Moonen, M.10
Ceuterick, C.11
De Jonghe, P.12
Van Broeckhoven, C.13
-
190
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: Clinical and molecular genetic study
-
Luoma, P.; Melberg, A.; Rinne, J.O.; Kaukonen, J.A.; Nupponen, N.N.; Chalmers, R.M.; Oldfors, A.; Rautakorpi, I.; Peltonen, L.; Majamaa, K.; Somer, H.; Suomalainen, A. Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: Clinical and molecular genetic study. Lancet 2004, 364, 875-82.
-
(2004)
Lancet
, vol.364
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
Kaukonen, J.A.4
Nupponen, N.N.5
Chalmers, R.M.6
Oldfors, A.7
Rautakorpi, I.8
Peltonen, L.9
Majamaa, K.10
Somer, H.11
Suomalainen, A.12
-
191
-
-
3442880816
-
Two families with autosomal dominant progressive external ophthalmoplegia
-
Kiechl, S.; Horvath, R.; Luoma, P.; Kiechl-Kohlendorfer, U.; Wallacher-Scholz, B.; Stucka, R.; Thaler, C.; Wanschitz, J.; Suomalainen, A.; Jaksch, M.; Willeit, J. Two families with autosomal dominant progressive external ophthalmoplegia. J. Neurol.Neurosurg. Psychiatry 2004, 75, 1125-8.
-
(2004)
J. Neurol.Neurosurg. Psychiatry
, vol.75
, pp. 1125-1128
-
-
Kiechl, S.1
Horvath, R.2
Luoma, P.3
Kiechl-Kohlendorfer, U.4
Wallacher-Scholz, B.5
Stucka, R.6
Thaler, C.7
Wanschitz, J.8
Suomalainen, A.9
Jaksch, M.10
Willeit, J.11
-
192
-
-
0042922454
-
Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma
-
Filosto, M.; Mancuso, M.; Nishigaki, Y.; Pancrudo, J.; Harati, Y.; Gooch, C.; Mankodi, A.; Bayne, L.; Bonilla, E.; Shanske, S.; Hirano, M.; DiMauro, S. Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma. Arch. Neurol. 2003, 60, 1279-84.
-
(2003)
Arch. Neurol
, vol.60
, pp. 1279-1284
-
-
Filosto, M.1
Mancuso, M.2
Nishigaki, Y.3
Pancrudo, J.4
Harati, Y.5
Gooch, C.6
Mankodi, A.7
Bayne, L.8
Bonilla, E.9
Shanske, S.10
Hirano, M.11
DiMauro, S.12
-
193
-
-
30344443067
-
Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish population
-
Gonzalez-Vioque, E.; Blazquez, A.; Fernandez-Moreira, D.; Bornstein, B.; Bautista, J.; Arpa, J.; Navarro, C.; Campos, Y.; Fernandez-Moreno, M.A.; Garesse, R.; Arenas, J.; Martin, M.A. Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish population. Arch. Neurol. 2006, 63, 107-11.
-
(2006)
Arch. Neurol
, vol.63
, pp. 107-111
-
-
Gonzalez-Vioque, E.1
Blazquez, A.2
Fernandez-Moreira, D.3
Bornstein, B.4
Bautista, J.5
Arpa, J.6
Navarro, C.7
Campos, Y.8
Fernandez-Moreno, M.A.9
Garesse, R.10
Arenas, J.11
Martin, M.A.12
-
194
-
-
33746239182
-
A new POLG1 mutation with peo and severe axonal and demyelinating sensory-motor neuropathy
-
Santoro, L.; Manganelli, F.; Lanzillo, R.; Tessa, A.; Barbieri, F.; Pierelli, F.; Di Giacinto, G.; Nigro, V.; Santorelli, F.M. A new POLG1 mutation with peo and severe axonal and demyelinating sensory-motor neuropathy. J. Neurol. 2006, 253, 869-74.
-
(2006)
J. Neurol
, vol.253
, pp. 869-874
-
-
Santoro, L.1
Manganelli, F.2
Lanzillo, R.3
Tessa, A.4
Barbieri, F.5
Pierelli, F.6
Di Giacinto, G.7
Nigro, V.8
Santorelli, F.M.9
-
195
-
-
0043033148
-
Digenic progressive external ophthalmoplegia in a sporadic patient: Recessive mutations in POLG and C10orf2/Twinkle
-
Van Goethem, G.; Lofgren, A.; Dermaut, B.; Ceuterick, C.; Martin, J.J.; Van Broeckhoven, C. Digenic progressive external ophthalmoplegia in a sporadic patient: Recessive mutations in POLG and C10orf2/Twinkle. Hum. Mutat. 2003, 22, 175-6.
-
(2003)
Hum. Mutat
, vol.22
, pp. 175-176
-
-
Van Goethem, G.1
Lofgren, A.2
Dermaut, B.3
Ceuterick, C.4
Martin, J.J.5
Van Broeckhoven, C.6
-
196
-
-
38349038411
-
Progressive external ophthalmoplegia and vision and hearing loss in a patient with mutations in POLG2 and OPA1
-
Ferraris, S.; Clark, S.; Garelli, E.; Davidzon, G.; Moore, S.A.; Kardon, R.H.; Bienstock, R.J.; Longley, M.J.; Mancuso, M.; Gutierrez Rios, P.; Hirano, M.; Copeland, W.C.; DiMauro, S. Progressive external ophthalmoplegia and vision and hearing loss in a patient with mutations in POLG2 and OPA1. Arch. Neurol. 2008, 65, 125-31
-
(2008)
Arch. Neurol
, vol.65
, pp. 125-131
-
-
Ferraris, S.1
Clark, S.2
Garelli, E.3
Davidzon, G.4
Moore, S.A.5
Kardon, R.H.6
Bienstock, R.J.7
Longley, M.J.8
Mancuso, M.9
Gutierrez Rios, P.10
Hirano, M.11
Copeland, W.C.12
DiMauro, S.13
-
197
-
-
33646859687
-
Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia
-
Longley, M.J.; Clark, S.; Yu Wai Man, C.; Hudson, G.; Durham, S.E.; Taylor, R.W.; Nightingale, S.; Turnbull, D.M.; Copeland, W.C.; Chinnery, P.F. Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. Am. J. Hum. Genet. 2006, 78, 1026-34.
-
(2006)
Am. J. Hum. Genet
, vol.78
, pp. 1026-1034
-
-
Longley, M.J.1
Clark, S.2
Yu Wai Man, C.3
Hudson, G.4
Durham, S.E.5
Taylor, R.W.6
Nightingale, S.7
Turnbull, D.M.8
Copeland, W.C.9
Chinnery, P.F.10
-
198
-
-
20144372363
-
Is the CAG repeat of mitochondrial DNA polymerase gamma (POLG) associated with male infertility? A multi-centre French study
-
Aknin-Seifer, I.E.; Touraine, R.L.; Lejeune, H.; Jimenez, C.; Chouteau, J.; Siffroi, J.P.; McElreavey, K.; Bienvenu, T.; Patrat, C.; Levy, R. Is the CAG repeat of mitochondrial DNA polymerase gamma (POLG) associated with male infertility? A multi-centre French study. Hum. Reprod. 2005, 20, 736-40.
-
(2005)
Hum. Reprod
, vol.20
, pp. 736-740
-
-
Aknin-Seifer, I.E.1
Touraine, R.L.2
Lejeune, H.3
Jimenez, C.4
Chouteau, J.5
Siffroi, J.P.6
McElreavey, K.7
Bienvenu, T.8
Patrat, C.9
Levy, R.10
-
199
-
-
0346055101
-
Frequent polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility
-
Jensen, M.; Leffers, H.; Petersen, J.H.; Nyboe Andersen, A.; Jorgensen, N.; Carlsen, E.; Jensen, T.K.; Skakkebaek, N.E.; Rajpert-De Meyts, E. Frequent polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility. Hum. Reprod. 2004, 19, 65-70.
-
(2004)
Hum. Reprod
, vol.19
, pp. 65-70
-
-
Jensen, M.1
Leffers, H.2
Petersen, J.H.3
Nyboe Andersen, A.4
Jorgensen, N.5
Carlsen, E.6
Jensen, T.K.7
Skakkebaek, N.E.8
Rajpert-De Meyts, E.9
-
200
-
-
0035185070
-
Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility
-
Rovio, A.T.; Marchington, D.R.; Donat, S.; Schuppe, H.C.; Abel, J.; Fritsche, E.; Elliott, D.J.; Laippala, P.; Ahola, A.L.; McNay, D.; Harrison, R.F.; Hughes, B.; Barrett, T.; Bailey, D.M.; Mehmet, D.; Jequier, A.M.; Hargreave, T.B.; Kao, S.H.; Cummins, J.M.; Barton, D.E.; Cooke, H.J.; Wei, Y.H.; Wichmann, L.; Poulton, J.; Jacobs, H.T. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Nat. Genet. 2001, 29, 261-2.
-
(2001)
Nat. Genet
, vol.29
, pp. 261-262
-
-
Rovio, A.T.1
Marchington, D.R.2
Donat, S.3
Schuppe, H.C.4
Abel, J.5
Fritsche, E.6
Elliott, D.J.7
Laippala, P.8
Ahola, A.L.9
McNay, D.10
Harrison, R.F.11
Hughes, B.12
Barrett, T.13
Bailey, D.M.14
Mehmet, D.15
Jequier, A.M.16
Hargreave, T.B.17
Kao, S.H.18
Cummins, J.M.19
Barton, D.E.20
Cooke, H.J.21
Wei, Y.H.22
Wichmann, L.23
Poulton, J.24
Jacobs, H.T.25
more..
-
201
-
-
16844382687
-
Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase gamma mutations
-
Winterthun, S.; Ferrari, G.; He, L.; Taylor, R.W.; Zeviani, M.; Turnbull, D.M.; Engelsen, B.A.; Moen, G.; Bindoff, L.A. Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase gamma mutations. Neurology 2005, 64, 1204-8.
-
(2005)
Neurology
, vol.64
, pp. 1204-1208
-
-
Winterthun, S.1
Ferrari, G.2
He, L.3
Taylor, R.W.4
Zeviani, M.5
Turnbull, D.M.6
Engelsen, B.A.7
Moen, G.8
Bindoff, L.A.9
-
202
-
-
57849140614
-
Molecular and clinical genetics of mitochondrial diseases due to POLG mutations
-
Wong, L.J.; Naviaux, R.K.; Brunetti-Pierri, N.; Zhang, Q.; Schmitt, E.S.; Truong, C.; Milone, M.; Cohen, B.H.; Wical, B.; Ganesh, J.; Basinger, A.A.; Burton, B.K.; Swoboda, K.; Gilbert, D.L.; Vanderver, A.; Saneto, R.P.; Maranda, B.; Arnold, G.; Abdenur, J.E.; Waters, P.J.; Copeland, W.C. Molecular and clinical genetics of mitochondrial diseases due to POLG mutations. Hum. Mutat. 2008,
-
(2008)
Hum. Mutat
-
-
Wong, L.J.1
Naviaux, R.K.2
Brunetti-Pierri, N.3
Zhang, Q.4
Schmitt, E.S.5
Truong, C.6
Milone, M.7
Cohen, B.H.8
Wical, B.9
Ganesh, J.10
Basinger, A.A.11
Burton, B.K.12
Swoboda, K.13
Gilbert, D.L.14
Vanderver, A.15
Saneto, R.P.16
Maranda, B.17
Arnold, G.18
Abdenur, J.E.19
Waters, P.J.20
Copeland, W.C.21
more..
-
203
-
-
20144388894
-
Infantile hepatocerebral syndromes associated with mutations in the mitochondrial DNA polymerase-gammaA
-
Ferrari, G.; Lamantea, E.; Donati, A.; Filosto, M.; Briem, E.; Carrara, F.; Parini, R.; Simonati, A.; Santer, R.; Zeviani, M. Infantile hepatocerebral syndromes associated with mutations in the mitochondrial DNA polymerase-gammaA. Brain 2005, 128, 723-31
-
(2005)
Brain
, vol.128
, pp. 723-731
-
-
Ferrari, G.1
Lamantea, E.2
Donati, A.3
Filosto, M.4
Briem, E.5
Carrara, F.6
Parini, R.7
Simonati, A.8
Santer, R.9
Zeviani, M.10
-
204
-
-
20444370205
-
POLG mutations and Alpers syndrome
-
Davidzon, G.; Mancuso, M.; Ferraris, S.; Quinzii, C.; Hirano, M.; Peters, H.L.; Kirby, D.; Thorburn, D.R.; DiMauro, S. POLG mutations and Alpers syndrome. Ann. Neurol. 2005, 57, 921-3.
-
(2005)
Ann. Neurol
, vol.57
, pp. 921-923
-
-
Davidzon, G.1
Mancuso, M.2
Ferraris, S.3
Quinzii, C.4
Hirano, M.5
Peters, H.L.6
Kirby, D.7
Thorburn, D.R.8
DiMauro, S.9
-
205
-
-
2142705756
-
POLG mutations associated with Alpers' syndrome and mitochondrial DNA depletion
-
Naviaux, R.K.; Nguyen, K.V. POLG mutations associated with Alpers' syndrome and mitochondrial DNA depletion. Ann. Neurol. 2004, 55, 706-12.
-
(2004)
Ann. Neurol
, vol.55
, pp. 706-712
-
-
Naviaux, R.K.1
Nguyen, K.V.2
-
206
-
-
27644453469
-
POLG mutations in Alpers syndrome
-
Nguyen, K.V.; Ostergaard, E.; Ravn, S.H.; Balslev, T.; Danielsen, E.R.; Vardag, A.; McKiernan, P.J.; Gray, G.; Naviaux, R.K. POLG mutations in Alpers syndrome. Neurology 2005, 65, 1493-5.
-
(2005)
Neurology
, vol.65
, pp. 1493-1495
-
-
Nguyen, K.V.1
Ostergaard, E.2
Ravn, S.H.3
Balslev, T.4
Danielsen, E.R.5
Vardag, A.6
McKiernan, P.J.7
Gray, G.8
Naviaux, R.K.9
-
207
-
-
44849107452
-
-
Uusimaa, J.; Hinttala, R.; Rantala, H.; Paivarinta, M.; Herva, R.; Roytta, M.; Soini, H.; Moilanen, J.S.; Remes, A.M.; Hassinen, I.E.; Majamaa, K. Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus. Epilepsia 2008, 49, 1038-45.
-
Uusimaa, J.; Hinttala, R.; Rantala, H.; Paivarinta, M.; Herva, R.; Roytta, M.; Soini, H.; Moilanen, J.S.; Remes, A.M.; Hassinen, I.E.; Majamaa, K. Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus. Epilepsia 2008, 49, 1038-45.
-
-
-
-
208
-
-
33748289552
-
Two novel mutations in POLG1 gene
-
Gago, M.F.; Rosas, M.J.; Guimaraes, J.; Ferreira, M.; Vilarinho, L.; Castro, L.; Carpenter, S. SANDO: Two novel mutations in POLG1 gene. Neuromuscul. Disord. 2006, 16, 507-9.
-
(2006)
Neuromuscul. Disord
, vol.16
, pp. 507-509
-
-
Gago, M.F.1
Rosas, M.J.2
Guimaraes, J.3
Ferreira, M.4
Vilarinho, L.5
Castro, L.6
Carpenter7
SANDO, S.8
-
209
-
-
20844442462
-
POLG mutations in neurodegenerative disorders with ataxia but no muscle involvement
-
Van Goethem, G.; Luoma, P.; Rantamaki, M.; Al Memar, A.; Kaakkola, S.; Hackman, P.; Krahe, R.; Lofgren, A.; Martin, J.J.; De Jonghe, P.; Suomalainen, A.; Udd, B.; Van Broeckhoven, C. POLG mutations in neurodegenerative disorders with ataxia but no muscle involvement. Neurology 2004, 63, 1251-7.
-
(2004)
Neurology
, vol.63
, pp. 1251-1257
-
-
Van Goethem, G.1
Luoma, P.2
Rantamaki, M.3
Al Memar, A.4
Kaakkola, S.5
Hackman, P.6
Krahe, R.7
Lofgren, A.8
Martin, J.J.9
De Jonghe, P.10
Suomalainen, A.11
Udd, B.12
Van Broeckhoven, C.13
-
210
-
-
48549101970
-
Sensory ataxic neuropathy with ophthalmoparesis caused by POLG mutations
-
Milone, M.; Brunetti-Pierri, N.; Tang, L.Y.; Kumar, N.; Mezei, M.M.; Josephs, K.; Powell, S.; Simpson, E.; Wong, L.J. Sensory ataxic neuropathy with ophthalmoparesis caused by POLG mutations. Neuromuscul. Disord. 2008, 18, 626-32.
-
(2008)
Neuromuscul. Disord
, vol.18
, pp. 626-632
-
-
Milone, M.1
Brunetti-Pierri, N.2
Tang, L.Y.3
Kumar, N.4
Mezei, M.M.5
Josephs, K.6
Powell, S.7
Simpson, E.8
Wong, L.J.9
-
211
-
-
55749085460
-
Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene
-
Remes, A.M.; Hinttala, R.; Karppa, M.; Soini, H.; Takalo, R.; Uusimaa, J.; Majamaa, K. Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene. Parkinsonism Relat. Disord. 2008,
-
(2008)
Parkinsonism Relat. Disord
-
-
Remes, A.M.1
Hinttala, R.2
Karppa, M.3
Soini, H.4
Takalo, R.5
Uusimaa, J.6
Majamaa, K.7
-
212
-
-
3543017697
-
A novel polymerase gamma mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism
-
Mancuso, M.; Filosto, M.; Oh, S.J.; DiMauro, S. A novel polymerase gamma mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism. Arch. Neurol. 2004, 61, 1777-9.
-
(2004)
Arch. Neurol
, vol.61
, pp. 1777-1779
-
-
Mancuso, M.1
Filosto, M.2
Oh, S.J.3
DiMauro, S.4
-
213
-
-
34948862122
-
Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease
-
Luoma, P.T.; Eerola, J.; Ahola, S.; Hakonen, A.H.; Hellstrom, O.; Kivisto, K.T.; Tienari, P.J.; Suomalainen, A. Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease. Neurology 2007, 69, 1152-9.
-
(2007)
Neurology
, vol.69
, pp. 1152-1159
-
-
Luoma, P.T.1
Eerola, J.2
Ahola, S.3
Hakonen, A.H.4
Hellstrom, O.5
Kivisto, K.T.6
Tienari, P.J.7
Suomalainen, A.8
-
214
-
-
54949136969
-
Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
-
Jensen, M.B.; Leffers, H.; Petersen, J.H.; Daugaard, G.; Skakkebaek, N.E.; Rajpert-De Meyts, E. Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer. Ann. Oncol. 2008,
-
(2008)
Ann. Oncol
-
-
Jensen, M.B.1
Leffers, H.2
Petersen, J.H.3
Daugaard, G.4
Skakkebaek, N.E.5
Rajpert-De Meyts, E.6
-
215
-
-
39749121457
-
POLG1 mutations cause a syndromic epilepsy with occipital lobe predilection
-
Engelsen, B.A.; Tzoulis, C.; Karlsen, B.; Lillebo, A.; Laegreid, L.M.; Aasly, J.; Zeviani, M.; Bindoff, L.A. POLG1 mutations cause a syndromic epilepsy with occipital lobe predilection. Brain 2008, 131, 818-28.
-
(2008)
Brain
, vol.131
, pp. 818-828
-
-
Engelsen, B.A.1
Tzoulis, C.2
Karlsen, B.3
Lillebo, A.4
Laegreid, L.M.5
Aasly, J.6
Zeviani, M.7
Bindoff, L.A.8
-
216
-
-
33749038700
-
Dominant inheritance of premature ovarian failure associated with mutant mitochondrial DNA polymerase gamma
-
Pagnamenta, A.T.; Taanman, J.W.; Wilson, C.J.; Anderson, N.E.; Marotta, R.; Duncan, A.J.; Bitner-Glindzicz, M.; Taylor, R.W.; Laskowski, A.; Thorburn, D.R.; Rahman, S. Dominant inheritance of premature ovarian failure associated with mutant mitochondrial DNA polymerase gamma. Hum. Reprod. 2006, 21, 2467-73.
-
(2006)
Hum. Reprod
, vol.21
, pp. 2467-2473
-
-
Pagnamenta, A.T.1
Taanman, J.W.2
Wilson, C.J.3
Anderson, N.E.4
Marotta, R.5
Duncan, A.J.6
Bitner-Glindzicz, M.7
Taylor, R.W.8
Laskowski, A.9
Thorburn, D.R.10
Rahman, S.11
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