Efficient and error-free replication past a minor-groove N 2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase

Molecular and Cellular Biology

Volumn 24, Issue 16, 2004, Pages 6900-6906

  Washington, M Todd ^a,c   Minko, Irina G ^a,d   Johnson, Robert E ^a   Haracska, Lajos ^a,e   Harris, Thomas M ^b   Lloyd, R Stephen ^a,d   Prakash, Satya ^a   Prakash, Louise ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALDEHYDE; DEOXYGUANOSINE DERIVATIVE; DNA POLYMERASE; DNA POLYMERASE REV1; DNA POLYMERASE ZETA; FUNGAL PROTEIN; GUANINE; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; DNA ADDUCT; DNA REPLICATION; DNA SYNTHESIS; DNA TEMPLATE; LIPID PEROXIDATION; OXIDATION; PRIORITY JOURNAL; PROTEIN DNA BINDING;

ACROLEIN; DNA; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANINE; HUMANS; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; NUCLEOTIDYLTRANSFERASES; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 3542992656     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.16.6900-6906.2004     Document Type: Article

References (40)

1. Ames, B. N., and L. S. Gold. 1991. Endogenous mutagens and the causes of aging and cancer. Mutat. Res. 250:3-16.
2. Chung, F.-L., H.-J. C. Chen, and R. G. Nath. 1996. Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis 17:2105-2111.
3. 2-propanodeoxyguanosine adducts. Mutat. Res. 424:71-81.
4. 2-propanodeoxygunosine adducts as endogenous DNA lesions in rodents and humans, p. 45-53. In B. Singer and H. Bartsch (ed.), DNA cyclic adducts. IARC Scientific Publications no. 150. International Agency for Cancer Research, Lyon France.
5. 2-propano-2′- deoxyguanosine. J. Biol. Chem. 276:9077-9082.
6. Esterbauer, H., R. J. Schaur, and H. Zollner. 1991. Chemistry and biochemistry of 4-hydroxynonenal, malonadehyde and related aldehydes. Free Radical Biol. Med. 11:81-128.
7. 6-methylguanine by yeast and human DNA polymerase η. Mol. Cell. Biol. 20:8001-8007.
8. Haracska, L., S. Prakash, and L. Prakash. 2002. Yeast Rev1 protein is a G template-specific DNA polymerase. J. Biol. Chem. 277:15546-15551.
9. Haracska, L., I. Unk, R. E. Johnson, E. Johansson, P. M. J. Burgers, S. Prakash, and L. Prakash. 2001. Roles of yeast DNA polymerases δ and ζ and of Rev1 in the bypass of abasic sites. Genes Dev. 15:945-954.
10. Haracska, L., S.-L. Yu, R. E. Johnson, L. Prakash, and S. Prakash. 2000. Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η. Nat. Genet. 25:458-461.
11. Johnson, R. E., L. Haracska, S. Prakash, and L. Prakash. 2001. Role of DNA polymerase η in the bypass of a (6-4) TT photoproduct. Mol. Cell. Biol. 21:3558-3563.
12. Johnson, R. E., C. M. Kondratick, S. Prakash, and L. Prakash. 1999. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science 285:263-265.
13. Johnson, R. E., S. Prakash, and L. Prakash. 1999. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη. Science 283:1001-1004.
14. Johnson, R. E., C. A. Torres-Ramos, T. Izumi, S. Mitra, S. Prakash, and L. Prakash. 1998. Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites. Genes Dev. 12:3137-3143.
15. Johnson, R. E., M. T. Washington, L. Haracska, S. Prakash, and L. Prakash. 2000. Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions. Nature 406:1015-1019.
16. Johnson, R. E., M. T. Washington, S. Prakash, and L. Prakash. 2000. Fidelity of human DNA polymerase η. J. Biol. Chem. 275:7447-7450.
17. Johnson, R. E., S.-L. Yu, S. Prakash, and L. Prakash. 2003. Yeast DNA polymerase zeta (ζ) is essential for error-free replication past thymine glycol. Genes Dev. 17:77-87.
18. Kanuri, M., I. G. Minko, L. V. Nechev, T. M. Harris, C. M. Harris, and R. S. Lloyd. 2002. Error prone translesion synthesis past γ- hydroypropanodeoxyguanosine, the primary acrolein-derived adduct in mammalian cells. J. Biol. Chem. 277:18257-18265.
19. 2-propano-2′-deoxyguanosine. J. Am. Chem. Soc. 124:9324-9325.
20. Kozekov, I. D., L. D. Nechev, A. Sanchez, C. M. Harris, R. S. Lloyd, and T. M. Harris. 2001. Interchain cross-linking of DNA mediated by the principal adduct of acrolein. Chem. Res. Toxicol. 14:1482-1485.
21. Kozekov, I. D., L. V. Nechev, M. S. Moseley, C. M. Harris, C. J. Rizzo, M. P. Stone, and T. M. Harris. 2003. DNA interchain cross-links formed by acrolein and crotonaldehyde. J. Am. Chem. Soc. 125:50-61.
22. 2-Deoxyguanosine adducts of acrolein, crotonaldehyde, and trans-4-hydroxynonenal cross-link to peptides via Schiff base linkage. J. Biol. Chem. 278:5970-5976.
23. Lawrence, C. W., and D. C. Hinkle. 1996. DNA polymerase ζ and the control of DNA damage induced mutagenesis in eukaryotes. Cancer Surveys 28:21-31.
24. Lee, Y., and L. M. Sayre. 1998. Reaffirmation that metabolism of polyamines by bovine plasma amine oxidase occurs strictly at the primary amino termini. J. Biol. Chem. 273:19490-19494.
25. Masutani, C., R. Kusumoto, A. Yamada, N. Dohmae, M. Yokoi, M. Yuasa, M. Araki, S. Iwai, K. Takio, and F. Hanaoka. 1999. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature 399:700-704.
26. Minko, I. G., M. T. Washington, M. Kanuri, L. Prakash, S. Prakash, and R. S. Lloyd. 2003. Translesion synthesis past acrolein-derived DNA adduct, γ-hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase η. J. Biol. Chem. 278:784-790.
27. 2-guanine adducts of 1,3-butadiene metabolites. J. Biol. Chem. 276:2517-2522.
28. 2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans. Proc. Natl. Acad. Sci. USA 91:7491-7495.
29. 2-propanodeoxyguanosine adducts as potential endogenous DNA lesions in rodent and human tissues. Cancer Res. 56:452-456.
30. Nechev, L. V., C. M. Harris, and T. M. Harris. 2000. Synthesis of nucleosides and oligonucleotides containing adducts of acrolein and vinyl chloride. Chem. Res. Toxicol. 13:421-429.
31. Nelson, J. R., C. W. Lawrence, and D. C. Hinkle. 1996. Deoxycytidyl transferase activity of yeast REV1 protein. Nature 382:729-731.
32. Nelson, J. R., C. W. Lawrence, and D. C. Hinkle. 1996. Thymine-thymine dimer bypass by yeast DNA polymerase ζ. Science 272:1646-1649.
33. Pan, J., and F.-L. Chung. 2002. Formation of cyclic deoxyguanosine adducts from ω-3 and ω-6 polyunsaturated fatty acids under oxidative conditions. Chem. Res. Toxicol. 15:367-372.
34. Prakash, S., and L. Prakash. 2002. Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev. 16:1872-1883.
35. 6-dA lesions catalyzed by DNA bypass polymerases. J. Biol. Chem. 277:30488-30494.
36. Washington, M. T., R. E. Johnson, S. Prakash, and L. Prakash. 2000. Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η. Proc. Natl. Acad. Sci. USA 97:3094-3099.
37. Washington, M. T., I. G. Minko, R. E. Johnson, W. T. Wolfle, T. M. Harris, R. S. Lloyd, S. Prakash, and L. Prakash. 2004. Efficient and error-free replication past a minor groove DNA adduct by the sequential action of human DNA polymerases ι and κ. Mol. Cell. Biol. 24:5687-5693.
38. Washington, M. T., L. Prakash, and S. Prakash. 2003. Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase η. Proc. Natl. Acad. Sci. USA 100:12093-12098.
39. Washington, M. T., W. T. Wolfle, T. E. Spratt, L. Prakash, and S. Prakash. 2003. Yeast DNA polymerase η makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate. Proc. Natl. Acad. Sci. USA 100:5113-5118.
40. Yang, I.-Y., F. Johnson, A. P. Grollman, and M. Moriya. 2002. Genotoxic mechanism for the major acrolein-derived deoxyguanosine adduct in human cells. Chem. Res. Toxicol. 15:160-164.