Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase η

Science

Volumn 318, Issue 5852, 2007, Pages 967-970

  Alt, Aaron ^a   Lammens, Katja ^a   Chiocchini, Claudia ^a   Lammens, Alfred ^a   Pieck, J Carsten ^a   Kuch, David ^a   Hopfner, Karl Peter ^a   Carell, Thomas ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DEOXYCYTIDINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE ETA; NUCLEOTIDYLTRANSFERASE;

CANCER; CHEMOTHERAPY; DNA; ENZYME; EUKARYOTE; TUMOR; ULTRAVIOLET RADIATION;

ARTICLE; CANCER THERAPY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CROSS LINKING; DNA BINDING; DNA CONFORMATION; DNA DAMAGE; DNA TEMPLATE; HYDROGEN BOND; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; BASE PAIRING; BINDING SITES; CISPLATIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DEOXYCYTOSINE NUCLEOTIDES; DNA; DNA ADDUCTS; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HYDROGEN BONDING; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TEMPLATES, GENETIC;

EUKARYOTA;

EID: 36048931023     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1148242     Document Type: Article

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