Structure of DNA polymerase β with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential

Structure

Volumn 11, Issue 1, 2003, Pages 121-127

  Krahn, Joseph M ^a   Beard, William A ^a   Miller, Holly ^b   Grollman, Arthur P ^b   Wilson, Samuel H ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

8 oxodeoxyguanine; DNA polymerase; Fidelity; Mutagenesis; Oxidative DNA damage; X ray crystallography

Indexed keywords

8 OXODEOXYGUANINE; DEOXYCYTIDINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA; GUANINE DERIVATIVE; NUCLEOTIDE; PARATHION; SUGAR PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME STRUCTURE; HUMAN; HYDROGEN BOND; PRIORITY JOURNAL;

BINDING SITES; DEOXYADENINE NUCLEOTIDES; DNA DAMAGE; DNA POLYMERASE BETA; DNA REPAIR; DNA REPLICATION; GUANINE; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 0037227566     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00930-9     Document Type: Article

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