Structures of phi29 DNA polymerase complexed with substrate: The mechanism of translocation in B-family polymerases

EMBO Journal

Volumn 26, Issue 14, 2007, Pages 3494-3505

  Berman, Andrea J ^a   Kamtekar, Satwik ^a,c   Goodman, Jessica L ^a   Lázaro, José M ^b   De Vega, Miguel ^b   Blanco, Luis ^b   Salas, Margarita ^b   Steitz, Thomas A ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c PFIZER INC   (United States)

Author keywords

DNA polymerase; Phi29; Structure; Translocation

Indexed keywords

DNA POLYMERASE; NUCLEOSIDE TRIPHOSPHATE; PHI29 REPLICATIVE DNA POLYMERASE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME TRANSLOCATION; DNA TEMPLATE; DOWNSTREAM PROCESSING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENE INSERTION SEQUENCE; GENE REPLICATION; GENE TRANSLOCATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FAMILY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; BACILLUS PHAGES; CRYSTALLOGRAPHY, X-RAY; DNA, VIRAL; DNA-DIRECTED DNA POLYMERASE; EXONUCLEASES; MODELS, MOLECULAR; PROTEIN TRANSPORT; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC; WATER;

EID: 34547175132     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601780     Document Type: Article

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