Mechanism of somatic hypermutation: Critical analysis of strand biased mutation signatures at A:T and G:C base pairs

Molecular Immunology

Volumn 46, Issue 3, 2009, Pages 305-320

  Steele, Edward J ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

ADAR1 deaminase; AID deaminase; DNA deamination model; DNA polymerase ; Reverse transcriptase model; Somatic hypermutation (SHM); Strand biased mutation

Indexed keywords

ADENOSINE; ALANINE; CYSTEINE; DNA POLYMERASE; GLYCINE; IMMUNOGLOBULIN; INOSINE; PROTEIN MSH2; PROTEIN MSH6; RNA POLYMERASE II; SINGLE STRANDED DNA; THREONINE; URACIL DNA GLYCOSIDASE;

ANTIGEN BINDING; B LYMPHOCYTE; BAGG ALBINO MOUSE; BASE PAIRING; DEAMINATION; DNA RECOMBINATION; DNA TRANSCRIPTION; HUMAN; MISMATCH REPAIR; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; POLYMERIZATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; REVIEW; SOMATIC HYPERMUTATION;

ANIMALS; BASE PAIRING; DEAMINATION; DNA; HUMANS; MUTATION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TRANSCRIPTION, GENETIC;

MUS;

EID: 57849133053     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.10.021     Document Type: Review

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