-
1
-
-
0026782875
-
Generation and analysis of random point mutations in an antibody CDR2 sequence: Many mutated antibodies lose their ability to bind antigen
-
Chen C, Roberts VA, Rittenberg MB. Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigen. J Exp Med 1992;176:855-866.
-
(1992)
J Exp Med
, vol.176
, pp. 855-866
-
-
Chen, C.1
Roberts, V.A.2
Rittenberg, M.B.3
-
2
-
-
0029047689
-
Enhancement and destruction of antibody function by somatic mutation: Unequal occurrence is controlled by V gene combinatorial associations
-
Chen C, Roberts VA, Stevens S, Brown M, Stenzel-Poore MP, Rittenberg MB. Enhancement and destruction of antibody function by somatic mutation: unequal occurrence is controlled by V gene combinatorial associations. EMBO J 1995;14:2784-2794.
-
(1995)
EMBO J
, vol.14
, pp. 2784-2794
-
-
Chen, C.1
Roberts, V.A.2
Stevens, S.3
Brown, M.4
Stenzel-Poore, M.P.5
Rittenberg, M.B.6
-
3
-
-
0031204378
-
Somatic mutation in VH complementarity-determining region 2 and framework region 2: Differential effects on antigen binding and Ig secretion
-
Wiens GD, Heldwein KA, Stenzel-Poore MP, Rittenberg MB. Somatic mutation in VH complementarity-determining region 2 and framework region 2: differential effects on antigen binding and Ig secretion. J Immunol 1997;159:1293-1302.
-
(1997)
J Immunol
, vol.159
, pp. 1293-1302
-
-
Wiens, G.D.1
Heldwein, K.A.2
Stenzel-Poore, M.P.3
Rittenberg, M.B.4
-
4
-
-
0028357638
-
Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementary determining region 2
-
Chen C, Martin TM, Stevens S, Rittenberg MB. Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementary determining region 2. J Exp Med 1994;180:577-586.
-
(1994)
J Exp Med
, vol.180
, pp. 577-586
-
-
Chen, C.1
Martin, T.M.2
Stevens, S.3
Rittenberg, M.B.4
-
6
-
-
0001578946
-
The influence of somatic mutation on clonal expansion
-
Shlomchik MJ, Litwin S, Weigert M. The influence of somatic mutation on clonal expansion. Prog Immunol 1989;7:415-423.
-
(1989)
Prog Immunol
, vol.7
, pp. 415-423
-
-
Shlomchik, M.J.1
Litwin, S.2
Weigert, M.3
-
7
-
-
0022745593
-
Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin
-
Caton AJ, Brownlee GG, Staudt LM, Gerhard W. Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin. EMBO J 1986;5:1577-1587.
-
(1986)
EMBO J
, vol.5
, pp. 1577-1587
-
-
Caton, A.J.1
Brownlee, G.G.2
Staudt, L.M.3
Gerhard, W.4
-
8
-
-
0022802257
-
Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP
-
Cumano A, Rajewsky K. Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP. EMBO J 1986;5:2459-2468.
-
(1986)
EMBO J
, vol.5
, pp. 2459-2468
-
-
Cumano, A.1
Rajewsky, K.2
-
9
-
-
0029063311
-
Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
-
Brezinschek HP, Brezinschek RI, Lipsky PE. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J Immunol 1995;155:190-202.
-
(1995)
J Immunol
, vol.155
, pp. 190-202
-
-
Brezinschek, H.P.1
Brezinschek, R.I.2
Lipsky, P.E.3
-
10
-
-
0031569118
-
Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
-
Dorner T, Brezinschek HP, Brezinschek RI, Foster SJ, Domiati-Saad R, Lipsky PE. Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J Immunol 1997;158:2779-2789.
-
(1997)
J Immunol
, vol.158
, pp. 2779-2789
-
-
Dorner, T.1
Brezinschek, H.P.2
Brezinschek, R.I.3
Foster, S.J.4
Domiati-Saad, R.5
Lipsky, P.E.6
-
11
-
-
0027434805
-
Somatic hypermutation in B cells: An optimal control treatment
-
Keppler TB, Perelson AS. Somatic hypermutation in B cells: an optimal control treatment. J Theor Biol 1993;164:37-64.
-
(1993)
J Theor Biol
, vol.164
, pp. 37-64
-
-
Keppler, T.B.1
Perelson, A.S.2
-
12
-
-
0031154831
-
Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts
-
Oprea M, Perelson AS. Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts. J Immunol 1997;158:5155-5162.
-
(1997)
J Immunol
, vol.158
, pp. 5155-5162
-
-
Oprea, M.1
Perelson, A.S.2
-
13
-
-
0023652377
-
Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses
-
Siekevitz M, Kocks C, Rajewsky K, Dildrop R. Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses. Cell 1987;48:757-770.
-
(1987)
Cell
, vol.48
, pp. 757-770
-
-
Siekevitz, M.1
Kocks, C.2
Rajewsky, K.3
Dildrop, R.4
-
14
-
-
0027454579
-
Recruiting memory B cells with changed antigenic specificity
-
Ellenberger J, Creadon G, Zhang X, Wysocki LJ. Recruiting memory B cells with changed antigenic specificity. J Immunol 1993;151:5272-5281.
-
(1993)
J Immunol
, vol.151
, pp. 5272-5281
-
-
Ellenberger, J.1
Creadon, G.2
Zhang, X.3
Wysocki, L.J.4
-
15
-
-
0023622462
-
Somatically mutated forms of a major anti-p-azophenylarsonate antibody variable region with drastically reduced affinity for p-azophenylarsonate: By-products of an antigen driven immune response?
-
Manser T, Parhami-Seren B, Margolies MN, Gefter ML. Somatically mutated forms of a major anti-p-azophenylarsonate antibody variable region with drastically reduced affinity for p-azophenylarsonate: by-products of an antigen driven immune response? J Exp Med 1987;166:1456-1463.
-
(1987)
J Exp Med
, vol.166
, pp. 1456-1463
-
-
Manser, T.1
Parhami-Seren, B.2
Margolies, M.N.3
Gefter, M.L.4
-
16
-
-
0025046393
-
Somatic mutations in antibodies expressed by germinal centre B cells early after primary immunization
-
Apel M, Berek C. Somatic mutations in antibodies expressed by germinal centre B cells early after primary immunization. Int Immunol 1990;2:813-819.
-
(1990)
Int Immunol
, vol.2
, pp. 813-819
-
-
Apel, M.1
Berek, C.2
-
17
-
-
0024799016
-
Mechanism of antigen-driven selection in germinal centres
-
Liu Y-J, Joshua DE, Williams GT, Smith CA, Gordon J, MacLennan ICM. Mechanism of antigen-driven selection in germinal centres. Nature 1989;342:929-931.
-
(1989)
Nature
, vol.342
, pp. 929-931
-
-
Liu, Y.-J.1
Joshua, D.E.2
Williams, G.T.3
Smith, C.A.4
Gordon, J.5
MacLennan, I.C.M.6
-
18
-
-
0027999391
-
The mechanism of autoantibody production in an autoimmune MRL/lpr mouse
-
Shan H, Shlomchik MJ, Marshak-Rothstein A, Pisetsky DS, Litwin S, Weigert MG. The mechanism of autoantibody production in an autoimmune MRL/lpr mouse. J Immunol 1994;153:5104-5120.
-
(1994)
J Immunol
, vol.153
, pp. 5104-5120
-
-
Shan, H.1
Shlomchik, M.J.2
Marshak-Rothstein, A.3
Pisetsky, D.S.4
Litwin, S.5
Weigert, M.G.6
-
19
-
-
0030001287
-
Tracing the development of single memory-lineage B cells in a highly defined immune response
-
Liu AH, Jena PK, Wysocki LJ. Tracing the development of single memory-lineage B cells in a highly defined immune response. J Exp Med 1996;183:2053-2063.
-
(1996)
J Exp Med
, vol.183
, pp. 2053-2063
-
-
Liu, A.H.1
Jena, P.K.2
Wysocki, L.J.3
-
21
-
-
0342740028
-
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity
-
Diamond B, Scharff MD. Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. Proc Natl Acad Sci USA 1984;81:5841-5844.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 5841-5844
-
-
Diamond, B.1
Scharff, M.D.2
-
22
-
-
0023279056
-
Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region
-
Giusti AM, Chien NC, Zack DJ, Shin S-U, Scharff MD. Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region. Proc Natl Acad Sci USA 1987;84:2926-2930.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2926-2930
-
-
Giusti, A.M.1
Chien, N.C.2
Zack, D.J.3
Shin, S.-U.4
Scharff, M.D.5
-
23
-
-
0025804934
-
Mapping and modification of an antibody hapten binding site: A site-directed mutagenesis study of McPC603
-
Glockshuber R, Stadlmuller J, Pluckthun A. Mapping and modification of an antibody hapten binding site: a site-directed mutagenesis study of McPC603. Biochemistry 1991;30:3049-3054.
-
(1991)
Biochemistry
, vol.30
, pp. 3049-3054
-
-
Glockshuber, R.1
Stadlmuller, J.2
Pluckthun, A.3
-
24
-
-
0026024276
-
The specificity properties that distinguish members of a set of homologous anti-digoxin antibodies are controlled by H chain mutations
-
Near RI, Bruccoleri R, Novotny J, Hudson NW, White A, Mudgett-Hunter M. The specificity properties that distinguish members of a set of homologous anti-digoxin antibodies are controlled by H chain mutations. J Immunol 1991;146:627-633.
-
(1991)
J Immunol
, vol.146
, pp. 627-633
-
-
Near, R.I.1
Bruccoleri, R.2
Novotny, J.3
Hudson, N.W.4
White, A.5
Mudgett-Hunter, M.6
-
25
-
-
0025784057
-
Single-chain site-specific mutations of fluorescein-amino acid contact residues in high affinity monoclonal antibody 4-4-20
-
Denzin LK, Whitlow M, Voss EW Jr. Single-chain site-specific mutations of fluorescein-amino acid contact residues in high affinity monoclonal antibody 4-4-20. J Biol Chem 1991;266:14095-14103.
-
(1991)
J Biol Chem
, vol.266
, pp. 14095-14103
-
-
Denzin, L.K.1
Whitlow, M.2
Voss Jr., E.W.3
-
26
-
-
0027501369
-
Heavy chain position 50 is a determinant of affinity and specificity for the anti-digoxin antibody 26-10
-
Schildbach JF, et al. Heavy chain position 50 is a determinant of affinity and specificity for the anti-digoxin antibody 26-10. J Biol Chem 1993;268:21739-21747.
-
(1993)
J Biol Chem
, vol.268
, pp. 21739-21747
-
-
Schildbach, J.F.1
-
27
-
-
0028222096
-
Site-directed mutagenesis of a catalytic antibody - An arginine and a histidine residue play key roles
-
Stewart JD, Roberts VA, Thomas NR, Getzoff ED, Benkovic SJ. Site-directed mutagenesis of a catalytic antibody - an arginine and a histidine residue play key roles. Biochemistry 1994;33:1994-2003.
-
(1994)
Biochemistry
, vol.33
, pp. 1994-2003
-
-
Stewart, J.D.1
Roberts, V.A.2
Thomas, N.R.3
Getzoff, E.D.4
Benkovic, S.J.5
-
28
-
-
0028087014
-
A single engineered amino acid substitution changes antibody fine specificity
-
Kussie PH, Parhamiseren B, Wysocki LJ, Margolies MN. A single engineered amino acid substitution changes antibody fine specificity. J Immunol 1994;152:146-152.
-
(1994)
J Immunol
, vol.152
, pp. 146-152
-
-
Kussie, P.H.1
Parhamiseren, B.2
Wysocki, L.J.3
Margolies, M.N.4
-
29
-
-
0028198737
-
Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody
-
Schildbach JF, et al. Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody. Protein Sci 1994;3:737-749.
-
(1994)
Protein Sci
, vol.3
, pp. 737-749
-
-
Schildbach, J.F.1
-
30
-
-
0028111743
-
Sequence statistics reliably predict stabilizing mutations in a protein domain
-
Steipe B, Schiller B, Pluckthun A, Steinbacher S. Sequence statistics reliably predict stabilizing mutations in a protein domain. J Mol Biol 1994;240:188-192.
-
(1994)
J Mol Biol
, vol.240
, pp. 188-192
-
-
Steipe, B.1
Schiller, B.2
Pluckthun, A.3
Steinbacher, S.4
-
31
-
-
0028305304
-
A role for destabilizing amino acid replacements in light-chain amyloidosis
-
Hurle MR, Helms LR, Li L, Chan WN, Wetzel R. A role for destabilizing amino acid replacements in light-chain amyloidosis. Proc Natl Acad Sci USA 1994;91:5446-5450.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5446-5450
-
-
Hurle, M.R.1
Helms, L.R.2
Li, L.3
Chan, W.N.4
Wetzel, R.5
-
32
-
-
0020641571
-
2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region
-
2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region. Cell 1983;33:77-83.
-
(1983)
Cell
, vol.33
, pp. 77-83
-
-
Wu, G.E.1
Hozumi, N.2
Murialdo, H.3
-
33
-
-
0025134871
-
A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion
-
Dul JL, Argon Y. A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion. Proc Natl Acad Sci USA 1990;87:8135-8139.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 8135-8139
-
-
Dul, J.L.1
Argon, Y.2
-
34
-
-
0023819528
-
Glycosylation of a VH residue of a monoclonal antibody against α(1→6) dextran increases its affinity for antigen
-
Wallick S, Kabat EA, Morrison SL. Glycosylation of a VH residue of a monoclonal antibody against α(1→6) dextran increases its affinity for antigen. J Exp Med 1988;168:1099-1109.
-
(1988)
J Exp Med
, vol.168
, pp. 1099-1109
-
-
Wallick, S.1
Kabat, E.A.2
Morrison, S.L.3
-
35
-
-
0015950548
-
Clonal restriction of the immune response to phosphorylcholine
-
Lee W, Cosenza H, Kohler H. Clonal restriction of the immune response to phosphorylcholine. Nature 1974;247:55-57.
-
(1974)
Nature
, vol.247
, pp. 55-57
-
-
Lee, W.1
Cosenza, H.2
Kohler, H.3
-
36
-
-
0016278801
-
Clonal nature of the immune response to phosphorylcholine. IV. Idiotype uniformity of binding site associated antigenic determinants among mouse anti-phosphorylcholine-binding antibodies
-
Claflin JL, Davie JM. Clonal nature of the immune response to phosphorylcholine. IV. Idiotype uniformity of binding site associated antigenic determinants among mouse anti-phosphorylcholine-binding antibodies. J Exp Med 1974;140:673-686.
-
(1974)
J Exp Med
, vol.140
, pp. 673-686
-
-
Claflin, J.L.1
Davie, J.M.2
-
37
-
-
0345001068
-
The murine antibody response to phosphocholine. Idiotypes, structures and binding sites
-
Perlmutter RM, ed. New York: Plenum Press
-
Claflin JL, Wolfe J, Maddalena A, Hudak S. The murine antibody response to phosphocholine. Idiotypes, structures and binding sites. In: Perlmutter RM, ed. The biology of idiotypes. New York: Plenum Press; 1984. p. 171-195.
-
(1984)
The Biology of Idiotypes
, pp. 171-195
-
-
Claflin, J.L.1
Wolfe, J.2
Maddalena, A.3
Hudak, S.4
-
38
-
-
0344468280
-
The molecular genetics of phosphocholine-binding antibodies
-
Perlmutter RM, ed. New York: Plenum Press
-
Perlmutter RM. The molecular genetics of phosphocholine-binding antibodies. In: Perlmutter RM, ed. The biology of idiotypes. New York: Plenum Press; 1984. p. 59-74.
-
(1984)
The Biology of Idiotypes
, pp. 59-74
-
-
Perlmutter, R.M.1
-
39
-
-
0019972628
-
Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae
-
Briles DE, Forman C, Hudak S, Claflin JL. Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae. J Exp Med 1982;156:1171-1185.
-
(1982)
J Exp Med
, vol.156
, pp. 1171-1185
-
-
Briles, D.E.1
Forman, C.2
Hudak, S.3
Claflin, J.L.4
-
40
-
-
0024159308
-
Genetics of the phosphocholine-specific antibody response to Streptococcus pneumoniae. Germ-line but not mutated T15 antibodies are dominantly selected
-
Claflin JL, Berry J. Genetics of the phosphocholine-specific antibody response to Streptococcus pneumoniae. Germ-line but not mutated T15 antibodies are dominantly selected. J Immunol 1988;141:4012-4019.
-
(1988)
J Immunol
, vol.141
, pp. 4012-4019
-
-
Claflin, J.L.1
Berry, J.2
-
41
-
-
0020687181
-
Restriction in IgM expression. IV. Affinity analysis of monoclonal antiphophorylcholine antibodies
-
Rodwell J, Gearhart PJ, Karush F. Restriction in IgM expression. IV. Affinity analysis of monoclonal antiphophorylcholine antibodies. J Immunol 1983;130:313-316.
-
(1983)
J Immunol
, vol.130
, pp. 313-316
-
-
Rodwell, J.1
Gearhart, P.J.2
Karush, F.3
-
42
-
-
0024368992
-
Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: Proposal of a structural mechanism
-
Chien NC, Roberts VA, Giusti AM, Scharff MD, Getzoff ED. Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism. Proc Natl Acad Sci USA 1989;86:5532-5536.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5532-5536
-
-
Chien, N.C.1
Roberts, V.A.2
Giusti, A.M.3
Scharff, M.D.4
Getzoff, E.D.5
-
43
-
-
0023053742
-
Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 Å
-
Satow Y, Cohen GH, Padlan EA, Davies DR. Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 Å. Mol Biol 1986;190:593-604.
-
(1986)
Mol Biol
, vol.190
, pp. 593-604
-
-
Satow, Y.1
Cohen, G.H.2
Padlan, E.A.3
Davies, D.R.4
-
44
-
-
0017411710
-
The protein data bank: A computer-based archival file for macromolecular structures
-
Bernstein FC, et al. The protein data bank: a computer-based archival file for macromolecular structures. J Mol Biol 1977;112:535-542.
-
(1977)
J Mol Biol
, vol.112
, pp. 535-542
-
-
Bernstein, F.C.1
-
45
-
-
0013484210
-
The three dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site
-
Segal DM, Padlan EA, Cohen GH, Rudikoff S, Potter M, Davies DR. The three dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site. Proc Natl Acad Sci USA 1974;71:4298-4302.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 4298-4302
-
-
Segal, D.M.1
Padlan, E.A.2
Cohen, G.H.3
Rudikoff, S.4
Potter, M.5
Davies, D.R.6
-
46
-
-
0016331193
-
The presence of arginyl residues and carboxylate groups in the phophorylcholine-binding site of mouse myeloma protein, HOPC 8
-
Grossberg AL, Krausz LM, Rendina L, Pressman D. The presence of arginyl residues and carboxylate groups in the phophorylcholine-binding site of mouse myeloma protein, HOPC 8. J Immunol 1974;113:1807-1814.
-
(1974)
J Immunol
, vol.113
, pp. 1807-1814
-
-
Grossberg, A.L.1
Krausz, L.M.2
Rendina, L.3
Pressman, D.4
-
47
-
-
0343125296
-
Unequal distribution of replacement mutations in kappa and lambda light chains and their associated heavy chains: The group II antibody response to phosphocholine-KLH
-
Steele EJ, ed. Boca Raton: CRC Press
-
Stenzel-Poore MP, Rittenberg MB. Unequal distribution of replacement mutations in kappa and lambda light chains and their associated heavy chains: the group II antibody response to phosphocholine-KLH. In: Steele EJ, ed. Somatic hypermutations in V-regions. Boca Raton: CRC Press; 1991. p. 96-103.
-
(1991)
Somatic Hypermutations in V-regions
, pp. 96-103
-
-
Stenzel-Poore, M.P.1
Rittenberg, M.B.2
-
48
-
-
0029961133
-
The imprint of somatic hypermutation on the repertoire of human germline V genes
-
Tomlinson IM, Walter G, Jones PT, Dear PH, Sonnhammer EL, Winter G. The imprint of somatic hypermutation on the repertoire of human germline V genes. J Mol Biol 1996;256:813-817.
-
(1996)
J Mol Biol
, vol.256
, pp. 813-817
-
-
Tomlinson, I.M.1
Walter, G.2
Jones, P.T.3
Dear, P.H.4
Sonnhammer, E.L.5
Winter, G.6
-
49
-
-
0002188768
-
The molecular evolution of the immune response
-
Manser T, Wysocki LJ, Gridley T, Near RI, Gefter M. The molecular evolution of the immune response. Immunol Today 1985;6:94-101.
-
(1985)
Immunol Today
, vol.6
, pp. 94-101
-
-
Manser, T.1
Wysocki, L.J.2
Gridley, T.3
Near, R.I.4
Gefter, M.5
-
50
-
-
0028289241
-
Anatomy of the antibody molecule
-
Padlan EA. Anatomy of the antibody molecule. Mol Immunol 1994;31:169-217.
-
(1994)
Mol Immunol
, vol.31
, pp. 169-217
-
-
Padlan, E.A.1
-
51
-
-
0028798104
-
Identification of specificity-determining residues in antibodies
-
Padlan EA, Abergel C, Tipper JP. Identification of specificity-determining residues in antibodies. FASEB J 1995;9:133-139.
-
(1995)
FASEB J
, vol.9
, pp. 133-139
-
-
Padlan, E.A.1
Abergel, C.2
Tipper, J.P.3
-
52
-
-
0028875542
-
Evaluation of loss and change of specificity resulting from random mutagenesis of an antibody VH region
-
Casson LP, Manser T. Evaluation of loss and change of specificity resulting from random mutagenesis of an antibody VH region. J Immunol 1995;155:5647-5654.
-
(1995)
J Immunol
, vol.155
, pp. 5647-5654
-
-
Casson, L.P.1
Manser, T.2
-
53
-
-
0030974783
-
Sequence changes at the V-D junction of the VH1 heavy chain of anti-phosphocholine antibodies alter binding to and protection against Streptococcus pneumoniae
-
Guo WX, Burger AM, Fischer RT, Sieckmann DG, Longo DL, Kenny JJ. Sequence changes at the V-D junction of the VH1 heavy chain of anti-phosphocholine antibodies alter binding to and protection against Streptococcus pneumoniae. Int Immunol 1997;9:665-677.
-
(1997)
Int Immunol
, vol.9
, pp. 665-677
-
-
Guo, W.X.1
Burger, A.M.2
Fischer, R.T.3
Sieckmann, D.G.4
Longo, D.L.5
Kenny, J.J.6
-
54
-
-
0030009781
-
Tolerance to single, but not multiple, amino acid replacements in antibody VH CDR2. A means of minimizing B cell wastage from somatic hypermutation?
-
Brown M, Rittenberg MB, Chen C, Roberts VA. Tolerance to single, but not multiple, amino acid replacements in antibody VH CDR2. A means of minimizing B cell wastage from somatic hypermutation? J Immunol 1996;156:3285-3291.
-
(1996)
J Immunol
, vol.156
, pp. 3285-3291
-
-
Brown, M.1
Rittenberg, M.B.2
Chen, C.3
Roberts, V.A.4
-
56
-
-
0026537575
-
Immunologic memory to phosphocholine keyhole limpet hemocyanin. Recurrent mutations in the lambda 1 light chain increase affinity for antigen
-
Brown M, et al. Immunologic memory to phosphocholine keyhole limpet hemocyanin. Recurrent mutations in the lambda 1 light chain increase affinity for antigen. J Immunol 1992;148:339-346.
-
(1992)
J Immunol
, vol.148
, pp. 339-346
-
-
Brown, M.1
-
57
-
-
0021855144
-
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
-
Clarke SH, Huppi K, Ruezinsky D, Staudt L, Gerhard W, Weigert M. Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin. J Exp Med 1985;161:687-704.
-
(1985)
J Exp Med
, vol.161
, pp. 687-704
-
-
Clarke, S.H.1
Huppi, K.2
Ruezinsky, D.3
Staudt, L.4
Gerhard, W.5
Weigert, M.6
-
58
-
-
0003575039
-
Stepwise intraclonal maturation of antibody affinity through somatic hypermutation
-
Kocks C, Rajewsky K. Stepwise intraclonal maturation of antibody affinity through somatic hypermutation. Proc Natl Acad Sci USA 1988;85:8206-8210.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8206-8210
-
-
Kocks, C.1
Rajewsky, K.2
-
59
-
-
0026060620
-
Intraclonal generation of antibody mutants in germinal centres
-
Jacob J, Kelsoe G, Rajewsky K, Weiss U. Intraclonal generation of antibody mutants in germinal centres. Nature 1991;354:389-392.
-
(1991)
Nature
, vol.354
, pp. 389-392
-
-
Jacob, J.1
Kelsoe, G.2
Rajewsky, K.3
Weiss, U.4
-
60
-
-
0026610897
-
The structure of pneumococcal lipoteichoic acid. Improved preparation, chemical and mass spectrometric studies
-
Behr T, Fischer VJ, Peter-Katalinic J, Egge H. The structure of pneumococcal lipoteichoic acid. Improved preparation, chemical and mass spectrometric studies. Eur J Biochem 1992;207:1063-1075.
-
(1992)
Eur J Biochem
, vol.207
, pp. 1063-1075
-
-
Behr, T.1
Fischer, V.J.2
Peter-Katalinic, J.3
Egge, H.4
-
61
-
-
0020064743
-
Immunologic memory to phosphorylcholine. II. PC-KLH induces two antibody populations that dominate different isotypes
-
Chang SP, Brown M, Rittenberg MB. Immunologic memory to phosphorylcholine. II. PC-KLH induces two antibody populations that dominate different isotypes. J Immunol 1982;128:702-706.
-
(1982)
J Immunol
, vol.128
, pp. 702-706
-
-
Chang, S.P.1
Brown, M.2
Rittenberg, M.B.3
-
62
-
-
0017104125
-
Structural basis for the specificity of phosphorylcholine-binding immunoglobulins
-
Padlan EA, Davies DR, Rudikoff S, Potter M. Structural basis for the specificity of phosphorylcholine-binding immunoglobulins. Immunochemistry 1976;13:945-949.
-
(1976)
Immunochemistry
, vol.13
, pp. 945-949
-
-
Padlan, E.A.1
Davies, D.R.2
Rudikoff, S.3
Potter, M.4
-
63
-
-
0015528117
-
Affinity labeling of a phosphorylcholine binding mouse myeloma protein
-
Chesebro B, Metzger H. Affinity labeling of a phosphorylcholine binding mouse myeloma protein. Biochemistry 1972;11:766-771.
-
(1972)
Biochemistry
, vol.11
, pp. 766-771
-
-
Chesebro, B.1
Metzger, H.2
-
64
-
-
0023821902
-
The adaptive potential of the memory response: Clonal recruitment and epitope recognition
-
Stenzel-Poore MP, Bruderer U, Rittenberg MB. The adaptive potential of the memory response: clonal recruitment and epitope recognition. Immunol Rev 1988;105:113-136.
-
(1988)
Immunol Rev
, vol.105
, pp. 113-136
-
-
Stenzel-Poore, M.P.1
Bruderer, U.2
Rittenberg, M.B.3
-
65
-
-
0030033588
-
Cation-pi interactions in chemistry and biology: A new view of benzene, Phe, Tyr, and Trp
-
Dougherty DA. Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science 1996;271:163-168.
-
(1996)
Science
, vol.271
, pp. 163-168
-
-
Dougherty, D.A.1
-
66
-
-
0030584783
-
Humanization and molecular modeling of the anti-CD4 monoclonal antibody, OKT4A
-
Pulito VL, et al. Humanization and molecular modeling of the anti-CD4 monoclonal antibody, OKT4A. J Immunol 1996;156:2840-2850.
-
(1996)
J Immunol
, vol.156
, pp. 2840-2850
-
-
Pulito, V.L.1
-
67
-
-
0027502201
-
Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth
-
Sato K, et al. Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth. Cancer Res 1993;53:851-856.
-
(1993)
Cancer Res
, vol.53
, pp. 851-856
-
-
Sato, K.1
-
68
-
-
0027404889
-
Modulation of antibody affinity by a non-contact residue
-
Schildbach JF, et al. Modulation of antibody affinity by a non-contact residue. Protein Sci 1993;2:206-214.
-
(1993)
Protein Sci
, vol.2
, pp. 206-214
-
-
Schildbach, J.F.1
-
69
-
-
0027955736
-
X-ray Structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody - Structural indications of the key role of VH residues 59 to 65
-
Eigenbrot C, et al. X-ray Structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody - structural indications of the key role of VH residues 59 to 65. Protein Struct Funct Genet 1994;18:49-62.
-
(1994)
Protein Struct Funct Genet
, vol.18
, pp. 49-62
-
-
Eigenbrot, C.1
-
70
-
-
0030821164
-
Structural insights into the evolution of an antibody combining site
-
Wedemayer GJ, Patten PA, Wang LH, Schultz PG, Stevens RC. Structural insights into the evolution of an antibody combining site. Science 1997;276:1665-1669.
-
(1997)
Science
, vol.276
, pp. 1665-1669
-
-
Wedemayer, G.J.1
Patten, P.A.2
Wang, L.H.3
Schultz, P.G.4
Stevens, R.C.5
-
71
-
-
0029991227
-
The immunological evolution of catalysis
-
Patten PA, et al. The immunological evolution of catalysis. Science 1996;271:1086-1091.
-
(1996)
Science
, vol.271
, pp. 1086-1091
-
-
Patten, P.A.1
-
72
-
-
0030053262
-
Analysis of antigen binding and idiotypic expression by antibodies with polyglycine replaced complementarity determining regions
-
Sompuram SR, Den W, Sharon J. Analysis of antigen binding and idiotypic expression by antibodies with polyglycine replaced complementarity determining regions. J Immunol 1996;156:1071-1081.
-
(1996)
J Immunol
, vol.156
, pp. 1071-1081
-
-
Sompuram, S.R.1
Den, W.2
Sharon, J.3
-
73
-
-
0026768470
-
A conditional secretory mutant in an Ig L chain is caused by replacement of a tyrosine/phenyalanine 87 with histidine
-
Dul JL, Burrone OR, Argon Y. A conditional secretory mutant in an Ig L chain is caused by replacement of a tyrosine/phenyalanine 87 with histidine. J Immunol 1992;149:1927-1933.
-
(1992)
J Immunol
, vol.149
, pp. 1927-1933
-
-
Dul, J.L.1
Burrone, O.R.2
Argon, Y.3
-
74
-
-
0031038002
-
Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding
-
Leitzgen K, Knittler MR, Haas IG. Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding. J Biol Chem 1997;272:3117-3123.
-
(1997)
J Biol Chem
, vol.272
, pp. 3117-3123
-
-
Leitzgen, K.1
Knittler, M.R.2
Haas, I.G.3
-
75
-
-
0028168756
-
Chimeric immunoglobulin light chains are secreted at different levels: Influence of framework-1 amino acids
-
Horwitz AH, Nadell R, Preugschat F, Better M. Chimeric immunoglobulin light chains are secreted at different levels: influence of framework-1 amino acids. Mol Immunol 1994;31:683-692.
-
(1994)
Mol Immunol
, vol.31
, pp. 683-692
-
-
Horwitz, A.H.1
Nadell, R.2
Preugschat, F.3
Better, M.4
-
76
-
-
0027174495
-
Affinity maturation leads to differential expression of multiple copies of a κ light-chain transgene
-
Lozano F, Rada C, Jarvis JM, Milstein C. Affinity maturation leads to differential expression of multiple copies of a κ light-chain transgene. Nature 1993;363:271-273.
-
(1993)
Nature
, vol.363
, pp. 271-273
-
-
Lozano, F.1
Rada, C.2
Jarvis, J.M.3
Milstein, C.4
-
77
-
-
0026331458
-
Maturation of the immune response in germinal centers
-
Berek C, Berger A, Apel M. Maturation of the immune response in germinal centers. Cell 1991;67:1121-1129.
-
(1991)
Cell
, vol.67
, pp. 1121-1129
-
-
Berek, C.1
Berger, A.2
Apel, M.3
-
78
-
-
0027305024
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells
-
Jacob J, Przylepa J, Miller C, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. J Exp Med 1993;178:1293-1307.
-
(1993)
J Exp Med
, vol.178
, pp. 1293-1307
-
-
Jacob, J.1
Przylepa, J.2
Miller, C.3
Kelsoe, G.4
-
79
-
-
0025955528
-
Mutation and selection during the secondary response to 2-phenyloxazolone
-
Rada C, Gupta SK, Gherardi E, Milstein C. Mutation and selection during the secondary response to 2-phenyloxazolone. Proc Natl Acad Sci USA 1991;88:5508-5512.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5508-5512
-
-
Rada, C.1
Gupta, S.K.2
Gherardi, E.3
Milstein, C.4
-
80
-
-
15844406352
-
Nonsense mutations inhibit RNA splicing in a cell-free system: Recognition of mutant codon is independent of protein synthesis
-
Aoufouchi S, Yelamos J, Milstein C. Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis. Cell 1996;85:415-422.
-
(1996)
Cell
, vol.85
, pp. 415-422
-
-
Aoufouchi, S.1
Yelamos, J.2
Milstein, C.3
-
82
-
-
0025230696
-
Developmental regulation of IgM secretion: The role of the carboxy-terminal cysteine
-
Sitia R, et al. Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine. Cell 1990;60:781-790.
-
(1990)
Cell
, vol.60
, pp. 781-790
-
-
Sitia, R.1
-
83
-
-
0029944851
-
Formation of reversible disulfide bonds with the protein matrix of the endoplasmic reticulum correlates with the retention of unassembled Ig light chains
-
Reddy P, Sparvoli A, Fagioli C, Fassina G, Sitia R. Formation of reversible disulfide bonds with the protein matrix of the endoplasmic reticulum correlates with the retention of unassembled Ig light chains. EMBO J 1996;15:2077-2085.
-
(1996)
EMBO J
, vol.15
, pp. 2077-2085
-
-
Reddy, P.1
Sparvoli, A.2
Fagioli, C.3
Fassina, G.4
Sitia, R.5
-
85
-
-
0030588683
-
Deletion in HCDR3 rescues T15 antibody mutants from a secretion defect caused by mutations in HCDR2
-
Martin TM, Kowalczyk C, Stevens S, Wiens GD, Stenzel-Poore MP, Rittenberg MB. Deletion in HCDR3 rescues T15 antibody mutants from a secretion defect caused by mutations in HCDR2. J Immunol 1996;157:4341-4346.
-
(1996)
J Immunol
, vol.157
, pp. 4341-4346
-
-
Martin, T.M.1
Kowalczyk, C.2
Stevens, S.3
Wiens, G.D.4
Stenzel-Poore, M.P.5
Rittenberg, M.B.6
-
86
-
-
0025856601
-
Kinetic maturation of an immune response
-
Foote J, Milstein C. Kinetic maturation of an immune response. Nature 1991;352:530-532.
-
(1991)
Nature
, vol.352
, pp. 530-532
-
-
Foote, J.1
Milstein, C.2
-
87
-
-
0029653368
-
Kinetic and affinity limits on antibodies produced during immune responses
-
Foote J, Eisen HN. Kinetic and affinity limits on antibodies produced during immune responses. Proc Natl Acad Sci USA 1995;92:1254-1261.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1254-1261
-
-
Foote, J.1
Eisen, H.N.2
-
88
-
-
0028948946
-
Complementarity, specificity and the nature of epitopes and paratopes in multivalent interactions
-
Greenspan NS, Cooper LJN. Complementarity, specificity and the nature of epitopes and paratopes in multivalent interactions. Immunol Today 1995;16:226-230.
-
(1995)
Immunol Today
, vol.16
, pp. 226-230
-
-
Greenspan, N.S.1
Cooper, L.J.N.2
-
89
-
-
0027380109
-
Influence of membrane Ig receptor density and affinity on B cell signaling by antigen. Implications for affinity maturation
-
George J, Penner SJ, Weber J, Berry J. Claflin JL. Influence of membrane Ig receptor density and affinity on B cell signaling by antigen. Implications for affinity maturation. J Immunol 1993;151:5955-5965.
-
(1993)
J Immunol
, vol.151
, pp. 5955-5965
-
-
George, J.1
Penner, S.J.2
Weber, J.3
Berry, J.4
Claflin, J.L.5
-
90
-
-
0030450401
-
Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation
-
Goyenechea B, Milstein C. Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation. Proc Natl Acad Sci USA 1996;93:13979-13984.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13979-13984
-
-
Goyenechea, B.1
Milstein, C.2
-
91
-
-
0030040277
-
Interactions of protein antigens with antibodies
-
Davies DR, Cohen GH. Interactions of protein antigens with antibodies. Proc Natl Acad Sci USA 1996;93:7-12.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7-12
-
-
Davies, D.R.1
Cohen, G.H.2
-
92
-
-
0024362070
-
On the attribution of binding energy in antigen-antibody complexes McPC603, D1.3, and HyHEL-5
-
Novotny J, Bruccoleri RE, Saul FA. On the attribution of binding energy in antigen-antibody complexes McPC603, D1.3, and HyHEL-5. Biochemistry 1989;28:4735-4749.
-
(1989)
Biochemistry
, vol.28
, pp. 4735-4749
-
-
Novotny, J.1
Bruccoleri, R.E.2
Saul, F.A.3
-
93
-
-
0027768856
-
The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme
-
Hawkins RE, Russell SJ, Baier M, Winter G. The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme. J Mol Biol 1993;234:958-964.
-
(1993)
J Mol Biol
, vol.234
, pp. 958-964
-
-
Hawkins, R.E.1
Russell, S.J.2
Baier, M.3
Winter, G.4
-
94
-
-
0027228495
-
Thermodynamic analysis of an antibody functional epitope
-
Kelley RF, O'Connell MP. Thermodynamic analysis of an antibody functional epitope. Biochemistry 1993;32:6828-6835.
-
(1993)
Biochemistry
, vol.32
, pp. 6828-6835
-
-
Kelley, R.F.1
O'Connell, M.P.2
-
95
-
-
0027761151
-
Antibody engineering by parsimonious mutagenesis
-
Balint RF, Larrick JW. Antibody engineering by parsimonious mutagenesis. Gene 1993;137:109-118.
-
(1993)
Gene
, vol.137
, pp. 109-118
-
-
Balint, R.F.1
Larrick, J.W.2
-
96
-
-
0022556211
-
Antigen-driven selection of virgin and memory B cells
-
MacLennan IC, Gray D. Antigen-driven selection of virgin and memory B cells. Immunol Rev 1986;91:61-85.
-
(1986)
Immunol Rev
, vol.91
, pp. 61-85
-
-
MacLennan, I.C.1
Gray, D.2
-
97
-
-
0027460507
-
Quantitative analysis of molecules which distinguish functional compartments within germinal centers
-
Hardie DL, Johnson GD, Khan M, MacLennan IC. Quantitative analysis of molecules which distinguish functional compartments within germinal centers. Eur J Immunol 1993;23:997-1004.
-
(1993)
Eur J Immunol
, vol.23
, pp. 997-1004
-
-
Hardie, D.L.1
Johnson, G.D.2
Khan, M.3
MacLennan, I.C.4
-
98
-
-
0345246156
-
Mechanism and significance of cell death within germinal centers
-
Cottier H, Odartchenko N, Schindler R, Congdon CC, eds. Berlin: Springer-Verlag
-
Odartchenko N, Lewerenz M, Sordat B, Roos B, Cottier H. Mechanism and significance of cell death within germinal centers. In: Cottier H, Odartchenko N, Schindler R, Congdon CC, eds. Germinal centers in immune responses. Berlin: Springer-Verlag; 1967. p. 212-217.
-
(1967)
Germinal Centers in Immune Responses
, pp. 212-217
-
-
Odartchenko, N.1
Lewerenz, M.2
Sordat, B.3
Roos, B.4
Cottier, H.5
-
99
-
-
0342711256
-
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
-
Lam KP, Kuhn R, Rajewsky K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 1997;90:1073-1083.
-
(1997)
Cell
, vol.90
, pp. 1073-1083
-
-
Lam, K.P.1
Kuhn, R.2
Rajewsky, K.3
-
100
-
-
0030900762
-
The changing preference of T and B cells for partners as T-dependent antibody responses develop
-
MacLennan ICM, et al. The changing preference of T and B cells for partners as T-dependent antibody responses develop. Immunol Rev 1997;156:53-66.
-
(1997)
Immunol Rev
, vol.156
, pp. 53-66
-
-
MacLennan, I.C.M.1
-
101
-
-
0027478391
-
Receptor editing in self-reactive bone marrow B cells
-
Tiegs SL, Russell DM, Nemazee D. Receptor editing in self-reactive bone marrow B cells. J Exp Med 1993;177:1009-1020.
-
(1993)
J Exp Med
, vol.177
, pp. 1009-1020
-
-
Tiegs, S.L.1
Russell, D.M.2
Nemazee, D.3
-
102
-
-
0028215530
-
Deletion and editing of B cells that express antibodies to DNA
-
Chen C, et al. Deletion and editing of B cells that express antibodies to DNA. J Immunol 1994;152:1970-1982.
-
(1994)
J Immunol
, vol.152
, pp. 1970-1982
-
-
Chen, C.1
-
103
-
-
0029553058
-
Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
-
Chen C, Nagy Z, Prak EL, Weigert M. Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. Immunity 1995;3:747-755.
-
(1995)
Immunity
, vol.3
, pp. 747-755
-
-
Chen, C.1
Nagy, Z.2
Prak, E.L.3
Weigert, M.4
-
104
-
-
0030764978
-
V(D)J recombinase activity in a subset of germinal center B lymphocytes
-
Han S, Dillon SR, Zheng B, Shimoda M, Schlissel MS, Kelsoe G. V(D)J recombinase activity in a subset of germinal center B lymphocytes. Science 1997;278:301-305.
-
(1997)
Science
, vol.278
, pp. 301-305
-
-
Han, S.1
Dillon, S.R.2
Zheng, B.3
Shimoda, M.4
Schlissel, M.S.5
Kelsoe, G.6
-
105
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
Hamers-Casterman C, et al. Naturally occurring antibodies devoid of light chains. Nature 1993;363:446-448.
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
Hamers-Casterman, C.1
-
106
-
-
0028168145
-
Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains
-
Muyldermans S, Atarhouch T, Saldanha J, Barbosa JA, Hamers R. Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains. Protein Eng 1994;7:1129-1135.
-
(1994)
Protein Eng
, vol.7
, pp. 1129-1135
-
-
Muyldermans, S.1
Atarhouch, T.2
Saldanha, J.3
Barbosa, J.A.4
Hamers, R.5
-
107
-
-
0029952779
-
Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells
-
Kanzler H, Kuppers R, Hansmann ML, Rajewsky K. Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. J Exp Med 1996;184:1495-1505.
-
(1996)
J Exp Med
, vol.184
, pp. 1495-1505
-
-
Kanzler, H.1
Kuppers, R.2
Hansmann, M.L.3
Rajewsky, K.4
-
108
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-
0029148418
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Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen
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Casson LP, Manser T. Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen. J Exp Med 1995;182:743-750.
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(1995)
J Exp Med
, vol.182
, pp. 743-750
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Casson, L.P.1
Manser, T.2
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