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Volumn 99, Issue E-SUPPL. 1, 2008, Pages

Isoflavones and the prevention of breast and prostate cancer: New perspectives opened by nutrigenomics

Author keywords

Breast cancer; Chemoprevention; Isoflavones; Nutrigenomics; Prostate cancer

Indexed keywords

AGLYCONE; DAIDZEIN; DRUG METABOLITE; EQUOL; ESTRADIOL; GENISTEIN; GLYCITEIN; ISOFLAVONE DERIVATIVE; LIGNAN DERIVATIVE; PHENOL DERIVATIVE; PHYTIC ACID; PHYTOESTROGEN; PLANT GLYCOSIDE; PLANT MEDICINAL PRODUCT; PROSTATE SPECIFIC ANTIGEN; PROTEINASE INHIBITOR; SAPONIN DERIVATIVE;

EID: 52949095784     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508965788     Document Type: Review
Times cited : (94)

References (278)
  • 1
    • 33749160353 scopus 로고    scopus 로고
    • Estimated Asian adult soy protein and isoflavone intakes
    • Messina M, Nagata C & Wu AH (2006) Estimated Asian adult soy protein and isoflavone intakes. Nutr Cancer 55, 1-12.
    • (2006) Nutr Cancer , vol.55 , pp. 1-12
    • Messina, M.1    Nagata, C.2    Wu, A.H.3
  • 2
    • 85047687822 scopus 로고    scopus 로고
    • Emerging evidence on the role of soy in reducing prostate cancer risk
    • Messina MJ (2003) Emerging evidence on the role of soy in reducing prostate cancer risk. Nutr Rev 61, 117-131.
    • (2003) Nutr Rev , vol.61 , pp. 117-131
    • Messina, M.J.1
  • 3
    • 2342649469 scopus 로고    scopus 로고
    • Phyto-oestrogens, their mechanism of action: Current evidence for a role in breast and prostate cancer
    • Magee PJ & Rowland IR (2004) Phyto-oestrogens, their mechanism of action: Current evidence for a role in breast and prostate cancer. Br J Nutr 91, 513-531.
    • (2004) Br J Nutr , vol.91 , pp. 513-531
    • Magee, P.J.1    Rowland, I.R.2
  • 4
    • 22944482178 scopus 로고    scopus 로고
    • Phytoestrogens in cancer prevention and therapy - mechanisms of their biological activity
    • Wietrzyk J, Gryniciewiez G & Opolski A (2005) Phytoestrogens in cancer prevention and therapy - mechanisms of their biological activity. Anticancer Res 25, 2357-2366.
    • (2005) Anticancer Res , vol.25 , pp. 2357-2366
    • Wietrzyk, J.1    Gryniciewiez, G.2    Opolski, A.3
  • 5
    • 0033991685 scopus 로고    scopus 로고
    • (20M) International trends and patterns of prostate cancer incidence and mortality
    • Hsing AW, Tsao L & Devesa SS (20M) International trends and patterns of prostate cancer incidence and mortality. Int J Cancer 85, 60-67.
    • Int J Cancer , vol.85 , pp. 60-67
    • Hsing, A.W.1    Tsao, L.2    Devesa, S.S.3
  • 6
    • 0025769201 scopus 로고
    • Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County
    • Shimizu H, Ross RK, Bernstein L, Yatani R, Henderson BE & Mack TM (1991) Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County. Br J Cancer 63, 963-966.
    • (1991) Br J Cancer , vol.63 , pp. 963-966
    • Shimizu, H.1    Ross, R.K.2    Bernstein, L.3    Yatani, R.4    Henderson, B.E.5    Mack, T.M.6
  • 7
    • 0032846010 scopus 로고    scopus 로고
    • Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants
    • Cook LS, Goldoft, M, Schwartz SM & Weiss NS (1999) Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants. J Urol 161, 152-155.
    • (1999) J Urol , vol.161 , pp. 152-155
    • Cook, L.S.1    Goldoft, M.2    Schwartz, S.M.3    Weiss, N.S.4
  • 8
    • 16344368667 scopus 로고    scopus 로고
    • Changing demography of prostate cancer in Asia
    • Sim HG & Cheng CWS (2005) Changing demography of prostate cancer in Asia. Eur J Cancer 41, 834-945.
    • (2005) Eur J Cancer , vol.41 , pp. 834-945
    • Sim, H.G.1    Cheng, C.W.S.2
  • 9
    • 24944470650 scopus 로고    scopus 로고
    • Meta-analysis of soy food and risk of prostate cancer in men
    • Yan L & Spitznagel EL (2005) Meta-analysis of soy food and risk of prostate cancer in men. Int J Cancer 117, 667-669.
    • (2005) Int J Cancer , vol.117 , pp. 667-669
    • Yan, L.1    Spitznagel, E.L.2
  • 12
    • 0036714766 scopus 로고    scopus 로고
    • Adolescent and adult soy intake and risk of breast cancer in Asian-Americans
    • Wu AH, Wan P, Hankin J, Tseng CC, Yu MC & Pike MC (2002) Adolescent and adult soy intake and risk of breast cancer in Asian-Americans. Carcinogenesis 23, 1491-1496.
    • (2002) Carcinogenesis , vol.23 , pp. 1491-1496
    • Wu, A.H.1    Wan, P.2    Hankin, J.3    Tseng, C.C.4    Yu, M.C.5    Pike, M.C.6
  • 13
    • 33750708260 scopus 로고    scopus 로고
    • An overview of the health effects of isoflavones with an emphasis on prostate cancer risk and prostate-specific antigen levels
    • Messina M, Kucuk O & Lampe JW (2006) An overview of the health effects of isoflavones with an emphasis on prostate cancer risk and prostate-specific antigen levels. J AOAC Int 89, 1121-1134.
    • (2006) J AOAC Int , vol.89 , pp. 1121-1134
    • Messina, M.1    Kucuk, O.2    Lampe, J.W.3
  • 15
    • 33748988463 scopus 로고    scopus 로고
    • Messina M, McCaskill-Stevens W & Lampe JW (2006) Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings. J Natl Cancer Inst 98, 1275-1284.
    • Messina M, McCaskill-Stevens W & Lampe JW (2006) Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings. J Natl Cancer Inst 98, 1275-1284.
  • 16
    • 0038407920 scopus 로고    scopus 로고
    • Mammographic densities in a one-year isoflavone intervention
    • Maskarinec GF, Williams AE Carlin L (2003) Mammographic densities in a one-year isoflavone intervention. Eur J Cancer Prev 12, 165-169.
    • (2003) Eur J Cancer Prev , vol.12 , pp. 165-169
    • Maskarinec, G.F.1    Williams, A.E.2    Carlin, L.3
  • 17
    • 7944234372 scopus 로고    scopus 로고
    • A 2-year soy intervention in premenopausal women does not change mammographic densities
    • Maskarinec G, Takata Y, Franke AA, Williams AE & Murphy SP (2004) A 2-year soy intervention in premenopausal women does not change mammographic densities. J Nutr 134, 3089-3094.
    • (2004) J Nutr , vol.134 , pp. 3089-3094
    • Maskarinec, G.1    Takata, Y.2    Franke, A.A.3    Williams, A.E.4    Murphy, S.P.5
  • 21
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach C, Williamson G, Morand C, Scalbert A & Remesy C (2005) Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81, 230S-242S.
    • (2005) Am J Clin Nutr , vol.81
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 24
    • 0347992819 scopus 로고    scopus 로고
    • Metabolism of the soy isoflavones daidzein, genistein and glycitein in human subjects. Identification of new metabolites having an intact isoflavonoid skeleton
    • Heinonen SM, Hoikkala A, Wahala K & Adlercreutz H (2003) Metabolism of the soy isoflavones daidzein, genistein and glycitein in human subjects. Identification of new metabolites having an intact isoflavonoid skeleton. J. Steroid Biochem Mol Biol 87, 285-299.
    • (2003) J. Steroid Biochem Mol Biol , vol.87 , pp. 285-299
    • Heinonen, S.M.1    Hoikkala, A.2    Wahala, K.3    Adlercreutz, H.4
  • 25
    • 2342517540 scopus 로고    scopus 로고
    • Studies of the in vitro intestinal metabolism of isoflavones aid in the identification of their urinary metabolites
    • Heinonen SM, Wahala K, Liukkonen KH, Aura AM, Poutanen K & Adlercreutz H (2004) Studies of the in vitro intestinal metabolism of isoflavones aid in the identification of their urinary metabolites. J Agric Food Chem 52, 2640-2646.
    • (2004) J Agric Food Chem , vol.52 , pp. 2640-2646
    • Heinonen, S.M.1    Wahala, K.2    Liukkonen, K.H.3    Aura, A.M.4    Poutanen, K.5    Adlercreutz, H.6
  • 26
    • 29944435941 scopus 로고    scopus 로고
    • Structural elucidation of hydroxylated metabolites of the isoflavan equol by gas chromatography - mass spectrometry and high-performance liquid chromatography-mass spectrometry
    • Rufer CE, Glatt H & Kulling SE (2006) Structural elucidation of hydroxylated metabolites of the isoflavan equol by gas chromatography - mass spectrometry and high-performance liquid chromatography-mass spectrometry. Drug Metab Dispos 34, 51-60.
    • (2006) Drug Metab Dispos , vol.34 , pp. 51-60
    • Rufer, C.E.1    Glatt, H.2    Kulling, S.E.3
  • 27
    • 0036898114 scopus 로고    scopus 로고
    • The clinical importance of the metabolite equol - a clue to the effectiveness of soy and its isoflavones
    • Setchell KD, Brown NM & Lydeking-Olsen E (2002) The clinical importance of the metabolite equol - a clue to the effectiveness of soy and its isoflavones. J Nutr 132, 3577-3584.
    • (2002) J Nutr , vol.132 , pp. 3577-3584
    • Setchell, K.D.1    Brown, N.M.2    Lydeking-Olsen, E.3
  • 28
    • 14344267019 scopus 로고    scopus 로고
    • Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health
    • Atkinson C, Frankenfeld CL & Lampe JW (2005) Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health. Exp Biol Med (Maywood) 230, 155-170.
    • (2005) Exp Biol Med (Maywood) , vol.230 , pp. 155-170
    • Atkinson, C.1    Frankenfeld, C.L.2    Lampe, J.W.3
  • 29
    • 33646406548 scopus 로고    scopus 로고
    • Prevalence of daidzein-metabolizing phenotypes differs between Caucasian and Korean American women and girls
    • Song KB, Atkinson C, Frankenfeld CL, Jokela T, Wahala K, Thomas WK & Lampe JW (2006) Prevalence of daidzein-metabolizing phenotypes differs between Caucasian and Korean American women and girls. J Nutr 136, 1347-1351.
    • (2006) J Nutr , vol.136 , pp. 1347-1351
    • Song, K.B.1    Atkinson, C.2    Frankenfeld, C.L.3    Jokela, T.4    Wahala, K.5    Thomas, W.K.6    Lampe, J.W.7
  • 30
    • 2342622175 scopus 로고    scopus 로고
    • Comparisons of percent equol producers between prostate cancer patients and controls: Case-controlled studies of isoflavones in Japanese, Korean and American residents
    • Akaza H, Miyanaga N, Takashima N, Naito S, Hirao Y, Tsukamoto T, Fujioka T, Mori M, Kim WJ, Song JM & Pantuck AJ (2004) Comparisons of percent equol producers between prostate cancer patients and controls: case-controlled studies of isoflavones in Japanese, Korean and American residents. Jpn J Clin Oncol 34, 86-89.
    • (2004) Jpn J Clin Oncol , vol.34 , pp. 86-89
    • Akaza, H.1    Miyanaga, N.2    Takashima, N.3    Naito, S.4    Hirao, Y.5    Tsukamoto, T.6    Fujioka, T.7    Mori, M.8    Kim, W.J.9    Song, J.M.10    Pantuck, A.J.11
  • 31
    • 0034046240 scopus 로고    scopus 로고
    • Premenopausal equol excretors show plasma hormone profiles associated with lowered risk of breast cancer
    • Duncan AM, MerzDemlow BE, Xu X, Phipps WR & Kurzer MS (2000) Premenopausal equol excretors show plasma hormone profiles associated with lowered risk of breast cancer. Cancer Epidemiol Biomarkers Prev 9, 581-586.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 581-586
    • Duncan, A.M.1    MerzDemlow, B.E.2    Xu, X.3    Phipps, W.R.4    Kurzer, M.S.5
  • 33
    • 14944360681 scopus 로고    scopus 로고
    • (2b05) The effect of soy consumption on the urinary 2:16-hydroxyestrone ratio in postmenopausal women depends on equol production status but is not influenced by probiotic consumption
    • Nettleton JA, Greany KA, Thomas W, Wangen KE, Adlercreutz H & Kurzer MS (2b05) The effect of soy consumption on the urinary 2:16-hydroxyestrone ratio in postmenopausal women depends on equol production status but is not influenced by probiotic consumption. J Nutr 135, 603-608.
    • J Nutr , vol.135 , pp. 603-608
    • Nettleton, J.A.1    Greany, K.A.2    Thomas, W.3    Wangen, K.E.4    Adlercreutz, H.5    Kurzer, M.S.6
  • 35
    • 34248184092 scopus 로고    scopus 로고
    • Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not
    • Niculescu MD, Pop EA, Fischer LM & Zeisel SH (2007) Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not. J Nutr Biochem 18, 380-390.
    • (2007) J Nutr Biochem , vol.18 , pp. 380-390
    • Niculescu, M.D.1    Pop, E.A.2    Fischer, L.M.3    Zeisel, S.H.4
  • 36
    • 33846404490 scopus 로고    scopus 로고
    • Optimization of terminal restriction fragment polymorphism (TRFLP) analysis of human gut microbiota
    • Li F, Hullar MAJ & Lampe JW (2007) Optimization of terminal restriction fragment polymorphism (TRFLP) analysis of human gut microbiota. J Microbiol Methods 68, 303-311.
    • (2007) J Microbiol Methods , vol.68 , pp. 303-311
    • Li, F.1    Hullar, M.A.J.2    Lampe, J.W.3
  • 38
    • 1842483155 scopus 로고    scopus 로고
    • Nutritional genomics: The next frontier in the postgenomic era
    • Kaput J & Rodriguez RL (2004) Nutritional genomics: The next frontier in the postgenomic era. Physiol Genomics 16, 166-177.
    • (2004) Physiol Genomics , vol.16 , pp. 166-177
    • Kaput, J.1    Rodriguez, R.L.2
  • 45
    • 34250017042 scopus 로고    scopus 로고
    • NMR-based metabolomics approach to target biomarkers for human prostate cancer
    • Jordan KW & Cheng LL (2007) NMR-based metabolomics approach to target biomarkers for human prostate cancer. Expert Rev Proteomics 4 389-400.
    • (2007) Expert Rev Proteomics , vol.4 , pp. 389-400
    • Jordan, K.W.1    Cheng, L.L.2
  • 46
    • 33845666901 scopus 로고    scopus 로고
    • Dietary prevention of hormone refractory prostate cancer mi Lobund-Wistar rats: A review of studies in a relevant animal model
    • Pollard M & Suckow MA (2006) Dietary prevention of hormone refractory prostate cancer mi Lobund-Wistar rats: A review of studies in a relevant animal model. Comp Med 56, 461-467.
    • (2006) Comp Med , vol.56 , pp. 461-467
    • Pollard, M.1    Suckow, M.A.2
  • 48
    • 0031970216 scopus 로고    scopus 로고
    • Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring
    • Hilakivi-Clarke L, Cho E & Clarke R (1998) Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring. Oncol Rep 5, 609-616.
    • (1998) Oncol Rep , vol.5 , pp. 609-616
    • Hilakivi-Clarke, L.1    Cho, E.2    Clarke, R.3
  • 51
    • 2442535038 scopus 로고    scopus 로고
    • Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis
    • Epub 2004 Jan 2016
    • Cabanes A, Wang M, Olivo S, DeAssis S, Gustafsson JA, Khan G & Hilakivi-Clarke L (2004) Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis. Carcinogenesis 25, 741-748, Epub 2004 Jan 2016.
    • (2004) Carcinogenesis , vol.25 , pp. 741-748
    • Cabanes, A.1    Wang, M.2    Olivo, S.3    DeAssis, S.4    Gustafsson, J.A.5    Khan, G.6    Hilakivi-Clarke, L.7
  • 53
    • 0032170032 scopus 로고    scopus 로고
    • Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo
    • Hsieh CY, Santell RC, Haslam SZ & Helferich WG (1998) Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo. Cancer Res 58 3833-3838.
    • (1998) Cancer Res , vol.58 , pp. 3833-3838
    • Hsieh, C.Y.1    Santell, R.C.2    Haslam, S.Z.3    Helferich, W.G.4
  • 54
    • 0035394121 scopus 로고    scopus 로고
    • Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner
    • Allred CD, Allred KF, Ju YH, Virant SM & Helferich WG (2001) Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Res 61, 5045-5050.
    • (2001) Cancer Res , vol.61 , pp. 5045-5050
    • Allred, C.D.1    Allred, K.F.2    Ju, Y.H.3    Virant, S.M.4    Helferich, W.G.5
  • 55
    • 0035158466 scopus 로고    scopus 로고
    • Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice
    • Ju YH, Allred CD, Allred KF, Karko KL, Doerge DR & Helferich WG (2001) Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice. J Nutr 131 , 2957-2962.
    • (2001) J Nutr , vol.131 , pp. 2957-2962
    • Ju, Y.H.1    Allred, C.D.2    Allred, K.F.3    Karko, K.L.4    Doerge, D.R.5    Helferich, W.G.6
  • 56
    • 0036569703 scopus 로고    scopus 로고
    • Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice
    • Ju YH, Doerge DR, Allred KF, Allred CD & Helferich WG (2002) Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice. Cancer Res 62, 2474-2477.
    • (2002) Cancer Res , vol.62 , pp. 2474-2477
    • Ju, Y.H.1    Doerge, D.R.2    Allred, K.F.3    Allred, C.D.4    Helferich, W.G.5
  • 57
    • 33745686651 scopus 로고    scopus 로고
    • Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations
    • Ju YH, Allred KF, Allred CD & Helferich WG (2006) Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations. Carcinogenesis 27, 1292-1299.
    • (2006) Carcinogenesis , vol.27 , pp. 1292-1299
    • Ju, Y.H.1    Allred, K.F.2    Allred, C.D.3    Helferich, W.G.4
  • 58
    • 0033956491 scopus 로고    scopus 로고
    • Influence of perinatal genistein exposure on the development of MNU-induced mammary carcinoma in female Sprague-Dawley rats
    • Yang JR, Nakagawa H, Tsuta K & Tsubura A (2000) Influence of perinatal genistein exposure on the development of MNU-induced mammary carcinoma in female Sprague-Dawley rats. Cancer Lett 149, 171-179.
    • (2000) Cancer Lett , vol.149 , pp. 171-179
    • Yang, J.R.1    Nakagawa, H.2    Tsuta, K.3    Tsubura, A.4
  • 59
    • 34447092455 scopus 로고    scopus 로고
    • In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumerigenesis
    • Su Y, Eason RR, Geng Y, Till SR, Badger TM & Simmen RCM (2007) In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumerigenesis. Carcinogenesis 28, 1046-1051.
    • (2007) Carcinogenesis , vol.28 , pp. 1046-1051
    • Su, Y.1    Eason, R.R.2    Geng, Y.3    Till, S.R.4    Badger, T.M.5    Simmen, R.C.M.6
  • 60
    • 33748746424 scopus 로고    scopus 로고
    • Neonatal exposure to the phytoestrogen gerristein alters mammary gland growth and developmental programming of hormone receptor levels
    • Padilla-Banks E, Jefferson WN & Newbold RR. (2006) Neonatal exposure to the phytoestrogen gerristein alters mammary gland growth and developmental programming of hormone receptor levels. Endocrinology 147, 4871-4882.
    • (2006) Endocrinology , vol.147 , pp. 4871-4882
    • Padilla-Banks, E.1    Jefferson, W.N.2    Newbold, R.R.3
  • 61
    • 33645633542 scopus 로고    scopus 로고
    • Maternal genistein alters coat color and protects A(vy) mouse offspring from obesity by modifying the fetal epigenome
    • Dolinoy DC, Weidman JR, Waterland RA & Jirtle RL (2006) Maternal genistein alters coat color and protects A(vy) mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect 114, 567-572.
    • (2006) Environ Health Perspect , vol.114 , pp. 567-572
    • Dolinoy, D.C.1    Weidman, J.R.2    Waterland, R.A.3    Jirtle, R.L.4
  • 62
  • 63
    • 0036790022 scopus 로고    scopus 로고
    • Soy isoflavones increase latency of spontaneous mammary tumors in mice
    • Jin Z & MacDonald RS (2002) Soy isoflavones increase latency of spontaneous mammary tumors in mice. J Nutr 132, 3186-3190.
    • (2002) J Nutr , vol.132 , pp. 3186-3190
    • Jin, Z.1    MacDonald, R.S.2
  • 64
    • 0036163784 scopus 로고    scopus 로고
    • Daidzein: Bioavailability, potential for reproductive toxicity, and breast cancer chemoprevention in female rats
    • Lamartiniere CA, Wang J, Smith-Johnson M & Eltoum IE (2002) Daidzein: bioavailability, potential for reproductive toxicity, and breast cancer chemoprevention in female rats. Toxicol Sci 65, 228-238.
    • (2002) Toxicol Sci , vol.65 , pp. 228-238
    • Lamartiniere, C.A.1    Wang, J.2    Smith-Johnson, M.3    Eltoum, I.E.4
  • 65
    • 33645343013 scopus 로고    scopus 로고
    • Effects of dietary daidzein and its metabolite: Equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovari-ectomized athymic mice
    • Ju YH, Fultz J, Allred KF, Doerge DR & Helferich WG (2006) Effects of dietary daidzein and its metabolite: Equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovari-ectomized athymic mice. Carcinogenesis 27, 856-863.
    • (2006) Carcinogenesis , vol.27 , pp. 856-863
    • Ju, Y.H.1    Fultz, J.2    Allred, K.F.3    Doerge, D.R.4    Helferich, W.G.5
  • 67
    • 0034062589 scopus 로고    scopus 로고
    • Inhibitory effects of bifidobacterium-fermented soy milk on 2-amino-1-methyl-6-phenylimidazo[4,5-blpyridine-induced rat mammary carcinogenesis, with a partial contribution of its component isoflavones
    • Ohta T, Nakatsugi S, Watanabe K, Kawamori T, Ishikawa F, Morotomi M, Sugie S, Toda T, Sugimura T & Wakabayashi K (2000) Inhibitory effects of bifidobacterium-fermented soy milk on 2-amino-1-methyl-6-phenylimidazo[4,5-blpyridine-induced rat mammary carcinogenesis, with a partial contribution of its component isoflavones. Carcinogenesis 21, 937-941.
    • (2000) Carcinogenesis , vol.21 , pp. 937-941
    • Ohta, T.1    Nakatsugi, S.2    Watanabe, K.3    Kawamori, T.4    Ishikawa, F.5    Morotomi, M.6    Sugie, S.7    Toda, T.8    Sugimura, T.9    Wakabayashi, K.10
  • 68
    • 0031783890 scopus 로고    scopus 로고
    • Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors
    • Wang C & Kurzer MS (1998) Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors. Nutr Cancer 31, 90-100.
    • (1998) Nutr Cancer , vol.31 , pp. 90-100
    • Wang, C.1    Kurzer, M.S.2
  • 69
    • 0034712219 scopus 로고    scopus 로고
    • Effects of phytoestrogens on aromatase, 3 beta and 17 beta-hydroxysteroid dehydrogenase activities and human breast cancer cells
    • Le Bail JC, Champavier Y, Chulia AJ & Habrioux G (2000) Effects of phytoestrogens on aromatase, 3 beta and 17 beta-hydroxysteroid dehydrogenase activities and human breast cancer cells. Life Sci 66, 1281-1291.
    • (2000) Life Sci , vol.66 , pp. 1281-1291
    • Le Bail, J.C.1    Champavier, Y.2    Chulia, A.J.3    Habrioux, G.4
  • 71
    • 0036257531 scopus 로고    scopus 로고
    • Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia
    • Hong SJ, Kim SI, Kwon SM, Lee JR & Chung BC (2002) Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia. Yonsei Med J 43, 236-241.
    • (2002) Yonsei Med J , vol.43 , pp. 236-241
    • Hong, S.J.1    Kim, S.I.2    Kwon, S.M.3    Lee, J.R.4    Chung, B.C.5
  • 72
    • 29344463843 scopus 로고    scopus 로고
    • Plasma and prostate phytoestrogen concentrations in prostate cancer patients after oral phytoestogen supplementation
    • Rannikko A, Petas A, Rannikko S & Adlercreutz H (2006) Plasma and prostate phytoestrogen concentrations in prostate cancer patients after oral phytoestogen supplementation. Prostate 66, 82-87.
    • (2006) Prostate , vol.66 , pp. 82-87
    • Rannikko, A.1    Petas, A.2    Rannikko, S.3    Adlercreutz, H.4
  • 76
    • 0037428403 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein
    • Dang ZC, Audinot V, Papapoulos SE, Boutin JA & Lowik CW (2003) Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein. J Biol Chem 278, 962-967.
    • (2003) J Biol Chem , vol.278 , pp. 962-967
    • Dang, Z.C.1    Audinot, V.2    Papapoulos, S.E.3    Boutin, J.A.4    Lowik, C.W.5
  • 79
    • 0037315155 scopus 로고    scopus 로고
    • Glucuronides are the main isoflavone, metabolites in women
    • Zhang Y, Hendrich S & Murphy PA (2003) Glucuronides are the main isoflavone, metabolites in women. J Nutr 133, 399-404.
    • (2003) J Nutr , vol.133 , pp. 399-404
    • Zhang, Y.1    Hendrich, S.2    Murphy, P.A.3
  • 80
    • 0032964360 scopus 로고    scopus 로고
    • Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations
    • Zhang Y, Song TT, Cunnick JE, Murphy PA & Hendrich S (1999) Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations. J Nutr 129, 399-405.
    • (1999) J Nutr , vol.129 , pp. 399-405
    • Zhang, Y.1    Song, T.T.2    Cunnick, J.E.3    Murphy, P.A.4    Hendrich, S.5
  • 84
    • 2442574033 scopus 로고    scopus 로고
    • Soy isoflavones-phytoestrogens and what else?
    • Barnes S (2004) Soy isoflavones-phytoestrogens and what else? J Nutr 134, 1225S-1228S.
    • (2004) J Nutr , vol.134
    • Barnes, S.1
  • 85
    • 33645213907 scopus 로고    scopus 로고
    • Isoflavones made simple - genistein's, agonist activity for the beta-type estrogen receptor mediates their health benefits
    • McCarty MF (2006) Isoflavones made simple - genistein's, agonist activity for the beta-type estrogen receptor mediates their health benefits. Med Hypotheses 66 1093-1114.
    • (2006) Med Hypotheses , vol.66 , pp. 1093-1114
    • McCarty, M.F.1
  • 86
    • 5144228218 scopus 로고    scopus 로고
    • Cell signaling pathways altered by natural chemopreventive agents
    • Sarkar FH & Li YW (2004) Cell signaling pathways altered by natural chemopreventive agents. Mutat Res 555, 53-64.
    • (2004) Mutat Res , vol.555 , pp. 53-64
    • Sarkar, F.H.1    Li, Y.W.2
  • 87
    • 0035050785 scopus 로고    scopus 로고
    • Role of estrogen receptor beta in estrogen action
    • Pettersson K & Gustafsson JA (2001) Role of estrogen receptor beta in estrogen action. Annu Rev Physiol 63, 165-192.
    • (2001) Annu Rev Physiol , vol.63 , pp. 165-192
    • Pettersson, K.1    Gustafsson, J.A.2
  • 88
    • 0037314762 scopus 로고    scopus 로고
    • Estrogen' receptor (ER)-beta reduces ER alpha-regulated gene transcription, supporting a 'Ying Yang' relationship between ER alpha and ER beta in mice
    • Lindberg MK, Moverare S, Skrtic S, Gao H, Dahlman-Wright K, Gustafsson JA & Ohlsson C (2003) Estrogen' receptor (ER)-beta reduces ER alpha-regulated gene transcription, supporting a 'Ying Yang' relationship between ER alpha and ER beta in mice. Mol Endocrinol 17, 203-208.
    • (2003) Mol Endocrinol , vol.17 , pp. 203-208
    • Lindberg, M.K.1    Moverare, S.2    Skrtic, S.3    Gao, H.4    Dahlman-Wright, K.5    Gustafsson, J.A.6    Ohlsson, C.7
  • 90
    • 0032145441 scopus 로고    scopus 로고
    • Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis
    • Leygue E, Dotzlaw H, Watson PH & Murphy LC (1998) Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis. Cancer Res 58, 3197-3201.
    • (1998) Cancer Res , vol.58 , pp. 3197-3201
    • Leygue, E.1    Dotzlaw, H.2    Watson, P.H.3    Murphy, L.C.4
  • 91
    • 0034861836 scopus 로고    scopus 로고
    • Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dopendent effects of two major phytoestrogens on human breast cancer cells
    • Maggiolini M, Bonofiglio D, Marsico S, Panno ML, Cenni B, Picard D & Ando S (2001) Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dopendent effects of two major phytoestrogens on human breast cancer cells. Mol Pharmacol 60, 595-602.
    • (2001) Mol Pharmacol , vol.60 , pp. 595-602
    • Maggiolini, M.1    Bonofiglio, D.2    Marsico, S.3    Panno, M.L.4    Cenni, B.5    Picard, D.6    Ando, S.7
  • 92
    • 0242298768 scopus 로고    scopus 로고
    • Ligand-induced regulation of ERalpha and ERbeta is indicative of human breast cancer cell proliferation
    • Power KA & Thompson LU (2003) Ligand-induced regulation of ERalpha and ERbeta is indicative of human breast cancer cell proliferation. Breast Cancer Res Treat 81, 209-221.
    • (2003) Breast Cancer Res Treat , vol.81 , pp. 209-221
    • Power, K.A.1    Thompson, L.U.2
  • 93
    • 33646834937 scopus 로고    scopus 로고
    • Modulation of estrogen receptor-beta isoforms by phytoestrogens in breast cancer cells
    • Cappelletti V, Modini P, Di Fronzo G & Daidone MG (2006) Modulation of estrogen receptor-beta isoforms by phytoestrogens in breast cancer cells. Int J Oncol 28, 1185-1191.
    • (2006) Int J Oncol , vol.28 , pp. 1185-1191
    • Cappelletti, V.1    Modini, P.2    Di Fronzo, G.3    Daidone, M.G.4
  • 96
    • 0037081891 scopus 로고    scopus 로고
    • Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate
    • Fritz WA, Wang J, Eltoum IE & Lamartiniere CA (2002) Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate. Mol Cell Endocrinol 186, 89-99.
    • (2002) Mol Cell Endocrinol , vol.186 , pp. 89-99
    • Fritz, W.A.1    Wang, J.2    Eltoum, I.E.3    Lamartiniere, C.A.4
  • 97
    • 33947626040 scopus 로고    scopus 로고
    • Genistein chemo-prevention of prostate cancer in TRAMP mice
    • Wang J, Eltoum IE & Lamartiniere CA (2007) Genistein chemo-prevention of prostate cancer in TRAMP mice. J Carcinog 6, 3.
    • (2007) J Carcinog , vol.6 , pp. 3
    • Wang, J.1    Eltoum, I.E.2    Lamartiniere, C.A.3
  • 98
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • Kuiper G, Carlsson B, Grandien K, Enmark E, Hagglad J, Nilsson S & Gustafsson JA (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138, 863-870.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Hagglad, J.5    Nilsson, S.6    Gustafsson, J.A.7
  • 100
    • 1642332240 scopus 로고    scopus 로고
    • Estrogen signaling: A subtle balance between ER1alpha and ERbeta
    • Matthews J & Gustafsson JA (2003) Estrogen signaling: A subtle balance between ER1alpha and ERbeta. Mol Interv 3, 281-292.
    • (2003) Mol Interv , vol.3 , pp. 281-292
    • Matthews, J.1    Gustafsson, J.A.2
  • 103
    • 0346849610 scopus 로고    scopus 로고
    • Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element
    • Kostelac D, Rechkemmer G & Briviba K (2003) Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element. J Agric Food Chem 51, 7632-7635.
    • (2003) J Agric Food Chem , vol.51 , pp. 7632-7635
    • Kostelac, D.1    Rechkemmer, G.2    Briviba, K.3
  • 104
    • 2342499956 scopus 로고    scopus 로고
    • Phyto-oestrogens and breast cancer chemoprevention
    • Limer JL & Speirs V (2004) Phyto-oestrogens and breast cancer chemoprevention. Breast Cancer Res 6, 119-127.
    • (2004) Breast Cancer Res , vol.6 , pp. 119-127
    • Limer, J.L.1    Speirs, V.2
  • 105
    • 0036827719 scopus 로고    scopus 로고
    • The mutant androgen receptor T877A mediates the proliferative but not the cytotoxic dose-dependent effects of genistein and quercetin on human LNCaP prostate cancer cells
    • Maggiolini M, Vivacqua A, Carpino A, Bonofiglio D, Fasanella G, Salerno M, Picard D & Ando S (2002) The mutant androgen receptor T877A mediates the proliferative but not the cytotoxic dose-dependent effects of genistein and quercetin on human LNCaP prostate cancer cells. Mol Pharmacol 62, 1027-1035.
    • (2002) Mol Pharmacol , vol.62 , pp. 1027-1035
    • Maggiolini, M.1    Vivacqua, A.2    Carpino, A.3    Bonofiglio, D.4    Fasanella, G.5    Salerno, M.6    Picard, D.7    Ando, S.8
  • 106
    • 0032516722 scopus 로고    scopus 로고
    • Genistein in the control of breast cancer cell growth: Insights into the mechanisn of action in vitro
    • Fioravanti L, Cappelletti V, Miodini P, Ronchi E, Brivio M & Di Fronzo G (1998) Genistein in the control of breast cancer cell growth: Insights into the mechanisn of action in vitro. Cancer Lett 130, 143-152.
    • (1998) Cancer Lett , vol.130 , pp. 143-152
    • Fioravanti, L.1    Cappelletti, V.2    Miodini, P.3    Ronchi, E.4    Brivio, M.5    Di Fronzo, G.6
  • 107
    • 31544474853 scopus 로고    scopus 로고
    • Wood CE, Register TC, Franke AA, Anthony MS & Cline JM (2006) Dietary soy isoflavones inhibit estrogen effects in the postmenopausal breast. Cancer Res 66, 1241-1249.
    • Wood CE, Register TC, Franke AA, Anthony MS & Cline JM (2006) Dietary soy isoflavones inhibit estrogen effects in the postmenopausal breast. Cancer Res 66, 1241-1249.
  • 108
    • 0029947174 scopus 로고    scopus 로고
    • Molecular effects of genistein on estrogen receptor mediated pathways
    • Wang TT, Sathyamoorthy N & Phang JM (1996) Molecular effects of genistein on estrogen receptor mediated pathways. Carinogenesis 17, 271-275.
    • (1996) Carinogenesis , vol.17 , pp. 271-275
    • Wang, T.T.1    Sathyamoorthy, N.2    Phang, J.M.3
  • 109
    • 0031424267 scopus 로고    scopus 로고
    • Differential effects of dietary phyto-oestrogens daidzein and equol on human breast cancer MCF-7 cells
    • Sathyamoorthy N & Wang TT (1997) Differential effects of dietary phyto-oestrogens daidzein and equol on human breast cancer MCF-7 cells. Eur J Cancer 33, 2384-2389.
    • (1997) Eur J Cancer , vol.33 , pp. 2384-2389
    • Sathyamoorthy, N.1    Wang, T.T.2
  • 111
    • 0034533197 scopus 로고    scopus 로고
    • Bel-2 is not reduced in the death of MCF-7 cells at low genistein concentration
    • Leung LK & Wang TT (2000) Bel-2 is not reduced in the death of MCF-7 cells at low genistein concentration. J Nutr 130, 2922-2926.
    • (2000) J Nutr , vol.130 , pp. 2922-2926
    • Leung, L.K.1    Wang, T.T.2
  • 112
    • 0036850979 scopus 로고    scopus 로고
    • Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects
    • Po LS, Wang TT, Chen ZY & Leung LK (2002) Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects. Br J Nutr 88, 463-469.
    • (2002) Br J Nutr , vol.88 , pp. 463-469
    • Po, L.S.1    Wang, T.T.2    Chen, Z.Y.3    Leung, L.K.4
  • 113
    • 0742324418 scopus 로고    scopus 로고
    • Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta
    • discussion 251
    • Bektic J, Berger AP, Pfeil K, Dobler G, Bartsch G & Klocker H (2004) Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta. Eur Urol 45, 245-251, discussion 251.
    • (2004) Eur Urol , vol.45 , pp. 245-251
    • Bektic, J.1    Berger, A.P.2    Pfeil, K.3    Dobler, G.4    Bartsch, G.5    Klocker, H.6
  • 114
    • 1842732153 scopus 로고    scopus 로고
    • Modulation of androgen receptor-dependent transcription by resveratrol and genistein in prostate cancer cells
    • Gao S, Liu GZ & Wang ZX (2004) Modulation of androgen receptor-dependent transcription by resveratrol and genistein in prostate cancer cells. Prostate 59, 214-225.
    • (2004) Prostate , vol.59 , pp. 214-225
    • Gao, S.1    Liu, G.Z.2    Wang, Z.X.3
  • 115
    • 0034202014 scopus 로고    scopus 로고
    • Inhibition of prostate specific antigen expression by genistein in prostate cancer cells
    • Davis JN, Muqim N, Bhuiyan M, Kucuk O, Pienta KJ & Sarkar FH (2000) Inhibition of prostate specific antigen expression by genistein in prostate cancer cells. Int J Oncol 16, 1091-1097.
    • (2000) Int J Oncol , vol.16 , pp. 1091-1097
    • Davis, J.N.1    Muqim, N.2    Bhuiyan, M.3    Kucuk, O.4    Pienta, K.J.5    Sarkar, F.H.6
  • 116
    • 0036270108 scopus 로고    scopus 로고
    • (20,02) Expression of prostate-specific antigen is transcriptionally regulated by genistein in prostate cancer cells
    • Davis JN, Kucuk O & Sarkar FH (20,02) Expression of prostate-specific antigen is transcriptionally regulated by genistein in prostate cancer cells. Mol Carcinog 34, 91-101.
    • Mol Carcinog , vol.34 , pp. 91-101
    • Davis, J.N.1    Kucuk, O.2    Sarkar, F.H.3
  • 117
    • 34447132197 scopus 로고    scopus 로고
    • Isoflavone-rich soy protein isolate suppresses androgen receptor expression without altering estrogen receptor-beta expression or serum hormonal profiles in men at high risk of prostate cancer
    • Hamilton-Reeves JM, Rebello SA, Thomas W, Slaton JW & Kurzer MS (2007) Isoflavone-rich soy protein isolate suppresses androgen receptor expression without altering estrogen receptor-beta expression or serum hormonal profiles in men at high risk of prostate cancer. J Nutr 137, 1769-1775.
    • (2007) J Nutr , vol.137 , pp. 1769-1775
    • Hamilton-Reeves, J.M.1    Rebello, S.A.2    Thomas, W.3    Slaton, J.W.4    Kurzer, M.S.5
  • 118
    • 0034834317 scopus 로고    scopus 로고
    • Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5 alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats
    • Weber KS, Setchell KDR, Stocco DM & Lephart ED (2001) Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5 alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats. J Endocrinol 170, 591-599.
    • (2001) J Endocrinol , vol.170 , pp. 591-599
    • Weber, K.S.1    Setchell, K.D.R.2    Stocco, D.M.3    Lephart, E.D.4
  • 119
    • 0036788365 scopus 로고    scopus 로고
    • Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components
    • Zhou JR, Yu LY, Zhong Y, Nassr RL Franke AA, Gaston SM & Blackburn GL (2002) Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components. Prostate 53, 143-153.
    • (2002) Prostate , vol.53 , pp. 143-153
    • Zhou, J.R.1    Yu, L.Y.2    Zhong, Y.3    Nassr, R.L.4    Franke, A.A.5    Gaston, S.M.6    Blackburn, G.L.7
  • 121
    • 0032100644 scopus 로고    scopus 로고
    • Increased UDP-glucuronosyltransferase activity and decreased prostate specific antigen production by biochanin A in prostate cancer cells
    • Sun XY, Plouzek CA, Henry JP, Wang TTY & Phang JM (1998) Increased UDP-glucuronosyltransferase activity and decreased prostate specific antigen production by biochanin A in prostate cancer cells. Cancer Res 58, 2379-2384.
    • (1998) Cancer Res , vol.58 , pp. 2379-2384
    • Sun, X.Y.1    Plouzek, C.A.2    Henry, J.P.3    Wang, T.T.Y.4    Phang, J.M.5
  • 122
    • 0028966126 scopus 로고
    • Estrogen-specific 17-beta-hydroxysteroid oxidoreductase type-1 (Ec-1.1.1.62) as a possible target for the action of phytoestrogens
    • Makela S, Poutanen M, Lehtimaki J, Kostian ML, Santti R & Vihko R (1995) Estrogen-specific 17-beta-hydroxysteroid oxidoreductase type-1 (Ec-1.1.1.62) as a possible target for the action of phytoestrogens. Proc Soc Exp Biol Med 208, 51-59.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 51-59
    • Makela, S.1    Poutanen, M.2    Lehtimaki, J.3    Kostian, M.L.4    Santti, R.5    Vihko, R.6
  • 123
    • 33644661286 scopus 로고    scopus 로고
    • Endocnine-disrupting chemicals as modulators of sex steroid synthesis
    • Whitehead SA & Rice S (2006) Endocnine-disrupting chemicals as modulators of sex steroid synthesis. Best Pract Res Clin Endocrinol Metab 20, 45-61.
    • (2006) Best Pract Res Clin Endocrinol Metab , vol.20 , pp. 45-61
    • Whitehead, S.A.1    Rice, S.2
  • 124
    • 0031915796 scopus 로고    scopus 로고
    • Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study
    • Kao YC, Zhou C, Sherman M, Laughton CA & Chen S (1998) Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study. Environ Health Perspect 106, 85-92.
    • (1998) Environ Health Perspect , vol.106 , pp. 85-92
    • Kao, Y.C.1    Zhou, C.2    Sherman, M.3    Laughton, C.A.4    Chen, S.5
  • 126
    • 0028972676 scopus 로고
    • Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids
    • Evans BA, Griffiths K & Morton MS (1995) Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J Endocrinol 147, 295-302.
    • (1995) J Endocrinol , vol.147 , pp. 295-302
    • Evans, B.A.1    Griffiths, K.2    Morton, M.S.3
  • 127
    • 0034950435 scopus 로고    scopus 로고
    • Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens?
    • Kirk CJ, Harris RM, Wood DM, Waring RH & Hughes PJ (2001) Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens? Biochem Soc Trans 29, 209-216.
    • (2001) Biochem Soc Trans , vol.29 , pp. 209-216
    • Kirk, C.J.1    Harris, R.M.2    Wood, D.M.3    Waring, R.H.4    Hughes, P.J.5
  • 128
    • 0031589170 scopus 로고    scopus 로고
    • Daidzein sulfoconjugates are potent inhibitors of sterol sulfatase (EC 3.1.6.2)
    • Wong CK & Keung WM (1997) Daidzein sulfoconjugates are potent inhibitors of sterol sulfatase (EC 3.1.6.2). Biochem Biophys Res Commun 233, 579-593.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 579-593
    • Wong, C.K.1    Keung, W.M.2
  • 130
    • 0037083352 scopus 로고    scopus 로고
    • The specific role of isoflavones on estrogen metabolism in premenopausal women
    • Kumar NB, Cantor A, Allen K, Riccardi D & Cox CE (2002) The specific role of isoflavones on estrogen metabolism in premenopausal women. Cancer 94, 1166-1174.
    • (2002) Cancer , vol.94 , pp. 1166-1174
    • Kumar, N.B.1    Cantor, A.2    Allen, K.3    Riccardi, D.4    Cox, C.E.5
  • 131
    • 0036197781 scopus 로고    scopus 로고
    • Hormonal effects of soy in premenopausal women and men
    • Kurzer MS (2002) Hormonal effects of soy in premenopausal women and men. J Nutr 132, 570S-573S.
    • (2002) J Nutr , vol.132
    • Kurzer, M.S.1
  • 132
    • 0028136777 scopus 로고
    • Biological effects of a diet of soy protein-rich in isoflavones on the menstrual-cycle of premenopausal women
    • Cassidy A, Bingham S & Setchell KDR (1994) Biological effects of a diet of soy protein-rich in isoflavones on the menstrual-cycle of premenopausal women. Am J Clin Nutr 60, 333-340.
    • (1994) Am J Clin Nutr , vol.60 , pp. 333-340
    • Cassidy, A.1    Bingham, S.2    Setchell, K.D.R.3
  • 133
    • 0027283967 scopus 로고
    • Genistein is an effective stimulator of sex-hormone binding globulin production in hepatocarcinoma human liver-cancer cells and suppresses proliferation of these cells in culture
    • Mousavi Y & Adlercreutz H (1993) Genistein is an effective stimulator of sex-hormone binding globulin production in hepatocarcinoma human liver-cancer cells and suppresses proliferation of these cells in culture. Steroids 58, 301-304.
    • (1993) Steroids , vol.58 , pp. 301-304
    • Mousavi, Y.1    Adlercreutz, H.2
  • 134
    • 34047103482 scopus 로고    scopus 로고
    • Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys
    • Register TC & Cline JM
    • Wood CE, Register TC & Cline JM (2007) Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys. Carcinogenesis 28, 801-808.
    • (2007) Carcinogenesis , vol.28 , pp. 801-808
    • Wood, C.E.1
  • 138
    • 0037657668 scopus 로고    scopus 로고
    • Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells
    • Mezei O, Banz WJ, Steger RW, Peluso MR, Winters TA & Shay N (2003) Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells. J Nutr 133, 1238-1243.
    • (2003) J Nutr , vol.133 , pp. 1238-1243
    • Mezei, O.1    Banz, W.J.2    Steger, R.W.3    Peluso, M.R.4    Winters, T.A.5    Shay, N.6
  • 140
    • 34047146022 scopus 로고    scopus 로고
    • Complementary actions of docosahexaenoic acid and genistein on COX-2, PGE(2) and invasiveness in MDA-MB-231 breast cancer cells
    • Horia E & Watkins BA (2007) Complementary actions of docosahexaenoic acid and genistein on COX-2, PGE(2) and invasiveness in MDA-MB-231 breast cancer cells. Carcinogenesis 28, 809-815.
    • (2007) Carcinogenesis , vol.28 , pp. 809-815
    • Horia, E.1    Watkins, B.A.2
  • 141
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, Shintaku P, Said JW, Heber D & Koeffler HP (1998) Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 95, 8906-8811.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8906-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 144
    • 4344568552 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands as cell-cycle modulators
    • Theocharis S, Margeli A, Vielh P & Kouraklis G (2004) Peroxisome proliferator-activated receptor-gamma ligands as cell-cycle modulators. Cancer Treat Rev 30, 545-554.
    • (2004) Cancer Treat Rev , vol.30 , pp. 545-554
    • Theocharis, S.1    Margeli, A.2    Vielh, P.3    Kouraklis, G.4
  • 146
    • 33846653083 scopus 로고    scopus 로고
    • Peroxisom e proliferator-activated receptor gamma: A novel target for cancer therapeutics?
    • Han S & Roman J (2007) Peroxisom e proliferator-activated receptor gamma: A novel target for cancer therapeutics? Anticancer Drugs 18, 237-244.
    • (2007) Anticancer Drugs , vol.18 , pp. 237-244
    • Han, S.1    Roman, J.2
  • 147
    • 0032839509 scopus 로고    scopus 로고
    • Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice
    • Zhou JR, Gugger ET, Tanaka T, Guo Y, Blackburn GL & Clinton SK (1999) Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice. J Nutr 119 1628-1635.
    • (1999) J Nutr , vol.119 , pp. 1628-1635
    • Zhou, J.R.1    Gugger, E.T.2    Tanaka, T.3    Guo, Y.4    Blackburn, G.L.5    Clinton, S.K.6
  • 148
    • 0033763830 scopus 로고    scopus 로고
    • Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells
    • Shen JC, Klein RD, Wei Q, Guan Y, Contois JH, Wang TT, Chang S & Hursting SD (2000) Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells. Mol Carcinog 29, 92-102.
    • (2000) Mol Carcinog , vol.29 , pp. 92-102
    • Shen, J.C.1    Klein, R.D.2    Wei, Q.3    Guan, Y.4    Contois, J.H.5    Wang, T.T.6    Chang, S.7    Hursting, S.D.8
  • 149
    • 0032456061 scopus 로고    scopus 로고
    • Genistein-induced upregulation of p21(WAF1), downregulation of cyclin B, and induction of apoptosis in prostate cancer cells
    • Davis JN, Singh B, Bhuiyan M & Sarkar FH (1998) Genistein-induced upregulation of p21(WAF1), downregulation of cyclin B, and induction of apoptosis in prostate cancer cells. Nutr Cancer 32, 123-131.
    • (1998) Nutr Cancer , vol.32 , pp. 123-131
    • Davis, J.N.1    Singh, B.2    Bhuiyan, M.3    Sarkar, F.H.4
  • 150
    • 0037474707 scopus 로고    scopus 로고
    • Soy extract inhibits mammary adenocarcinoma growth in a syngeneic mouse model
    • Hewitt AL & Singletary KW (2003) Soy extract inhibits mammary adenocarcinoma growth in a syngeneic mouse model. Cancer Lett 192, 133-143.
    • (2003) Cancer Lett , vol.192 , pp. 133-143
    • Hewitt, A.L.1    Singletary, K.W.2
  • 151
    • 0028150702 scopus 로고
    • Growth-ihibitry effects of the natural phyto-oestrogen genistein in MCF-7 human breast cancer cells
    • Pagliacci MC, Smacchia M, Migliorati G, Grignani F, Riccardi C & Nicoletti I (1994) Growth-ihibitry effects of the natural phyto-oestrogen genistein in MCF-7 human breast cancer cells. Eur J Cancer 30A, 1675-1682.
    • (1994) Eur J Cancer , vol.30 A , pp. 1675-1682
    • Pagliacci, M.C.1    Smacchia, M.2    Migliorati, G.3    Grignani, F.4    Riccardi, C.5    Nicoletti, I.6
  • 152
    • 0035871953 scopus 로고    scopus 로고
    • Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: Involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression
    • Frey RS, Li J & Singletary KW (2001) Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: Involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression. Biochem Pharmacol 61, 979-989.
    • (2001) Biochem Pharmacol , vol.61 , pp. 979-989
    • Frey, R.S.1    Li, J.2    Singletary, K.W.3
  • 154
  • 156
    • 33749053416 scopus 로고    scopus 로고
    • Identification of both Myt-1 and Wee-1 as necessary mediators of the p21-independent inactivation of the cdc-2/ cyclin B1 complex and growth inhibition of TRAMP cancer cells by genistein
    • Touny LH & Banerjee PP (2006) Identification of both Myt-1 and Wee-1 as necessary mediators of the p21-independent inactivation of the cdc-2/ cyclin B1 complex and growth inhibition of TRAMP cancer cells by genistein. Prostate 66, 1542-1555.
    • (2006) Prostate , vol.66 , pp. 1542-1555
    • Touny, L.H.1    Banerjee, P.P.2
  • 157
    • 2342626463 scopus 로고    scopus 로고
    • Genistein inversely affects tubulin-binding agent-induced apoptosis in human breast cancer cells
    • Liao CH, Pan SL, Guh JH & Teng CM (2004) Genistein inversely affects tubulin-binding agent-induced apoptosis in human breast cancer cells. Biochem Pharmacol 67, 2031-2038.
    • (2004) Biochem Pharmacol , vol.67 , pp. 2031-2038
    • Liao, C.H.1    Pan, S.L.2    Guh, J.H.3    Teng, C.M.4
  • 158
    • 0037224827 scopus 로고    scopus 로고
    • Genistein activates p38 mitogen-activated protein kinase, inactivates ERK1/ERK2 and decreases Cdc25C expression in immortalized human mammary epithelial cells
    • Frey RS & Singletary KW (2003) Genistein activates p38 mitogen-activated protein kinase, inactivates ERK1/ERK2 and decreases Cdc25C expression in immortalized human mammary epithelial cells. J Nutr 133, 226-231.
    • (2003) J Nutr , vol.133 , pp. 226-231
    • Frey, R.S.1    Singletary, K.W.2
  • 159
    • 0025936510 scopus 로고
    • cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
    • Gautier J, Solomon MJ, Booher RN, Bazan JF & Kirschner MW (1991) cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell 67, 197-211.
    • (1991) Cell , vol.67 , pp. 197-211
    • Gautier, J.1    Solomon, M.J.2    Booher, R.N.3    Bazan, J.F.4    Kirschner, M.W.5
  • 160
    • 0033587157 scopus 로고    scopus 로고
    • Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein
    • Li Y, Upadhyay S, Bhuiyan M & Sarkar FH (1999) Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein. Oncogene 18, 3166-3172.
    • (1999) Oncogene , vol.18 , pp. 3166-3172
    • Li, Y.1    Upadhyay, S.2    Bhuiyan, M.3    Sarkar, F.H.4
  • 161
    • 20444443930 scopus 로고    scopus 로고
    • Phytoestrogen exposure elevates PTEN levels
    • Waite KA, Sinden MR & Eng C (2005) Phytoestrogen exposure elevates PTEN levels. Hum Mol Genet 14, 1457-1463.
    • (2005) Hum Mol Genet , vol.14 , pp. 1457-1463
    • Waite, K.A.1    Sinden, M.R.2    Eng, C.3
  • 162
    • 33748655440 scopus 로고    scopus 로고
    • Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells
    • Eto I (2006) Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells. Cancer Cell Int 6, 20.
    • (2006) Cancer Cell Int , vol.6 , pp. 20
    • Eto, I.1
  • 163
    • 27144464477 scopus 로고    scopus 로고
    • The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN
    • Dave B, Eason RR, Till SR, Geng Y, Velarde MC, Badger TM & Simmen RC (2005) The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN. Carcinogenesis 26, 1793-1803.
    • (2005) Carcinogenesis , vol.26 , pp. 1793-1803
    • Dave, B.1    Eason, R.R.2    Till, S.R.3    Geng, Y.4    Velarde, M.C.5    Badger, T.M.6    Simmen, R.C.7
  • 164
    • 0037039712 scopus 로고    scopus 로고
    • Effect of flavonoids on cell cycle progression in prostate cancer cells
    • Kobayashi T, Nakata T & Kuzumaki T (2002) Effect of flavonoids on cell cycle progression in prostate cancer cells. Cancer Lett 176, 17-23.
    • (2002) Cancer Lett , vol.176 , pp. 17-23
    • Kobayashi, T.1    Nakata, T.2    Kuzumaki, T.3
  • 165
    • 0042261670 scopus 로고    scopus 로고
    • Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein
    • Kazi A, Daniel KG, Smith DM, Kumar NB & Dou QP (2003) Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Biochem Pharmacol 66 965-976.
    • (2003) Biochem Pharmacol , vol.66 , pp. 965-976
    • Kazi, A.1    Daniel, K.G.2    Smith, D.M.3    Kumar, N.B.4    Dou, Q.P.5
  • 166
    • 0035866339 scopus 로고    scopus 로고
    • Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells
    • Li X, Marani M, Mannucci R, Kinsey B, Andriani F, Nicoletti I, Denner L & Marcelli M (2001) Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells. Cancer Res 61, 1699-1706.
    • (2001) Cancer Res , vol.61 , pp. 1699-1706
    • Li, X.1    Marani, M.2    Mannucci, R.3    Kinsey, B.4    Andriani, F.5    Nicoletti, I.6    Denner, L.7    Marcelli, M.8
  • 167
    • 4143083764 scopus 로고    scopus 로고
    • A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo
    • Bemis DL, Capodice JL, Desai M, Buttyan R & Katz AE (2004) A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo. Clin Cancer Res 10, 5282-5292.
    • (2004) Clin Cancer Res , vol.10 , pp. 5282-5292
    • Bemis, D.L.1    Capodice, J.L.2    Desai, M.3    Buttyan, R.4    Katz, A.E.5
  • 168
    • 33645983347 scopus 로고    scopus 로고
    • Inhibitory effect of isoflavones on prostate cancer cells and PTEN gene
    • Cao F, Jin TY & Zhou YF (2006) Inhibitory effect of isoflavones on prostate cancer cells and PTEN gene. Biomed Environ Sci 19, 35-41.
    • (2006) Biomed Environ Sci , vol.19 , pp. 35-41
    • Cao, F.1    Jin, T.Y.2    Zhou, Y.F.3
  • 169
    • 16644367866 scopus 로고    scopus 로고
    • Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappa B/AP-1-dependent and - independent pathways
    • Valachovicova T, Slivova V, Bergman H, Shuherk J & Sliva D (2004) Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappa B/AP-1-dependent and - independent pathways. Int J Oncol 25, 1389-1395.
    • (2004) Int J Oncol , vol.25 , pp. 1389-1395
    • Valachovicova, T.1    Slivova, V.2    Bergman, H.3    Shuherk, J.4    Sliva, D.5
  • 170
    • 34547128144 scopus 로고    scopus 로고
    • Genistein induces the metastasis suppressor kangai-1 which mediates its anti-invasive effects in TRAMP cancer cells
    • El Touny LH & Banerjee PP (2007) Genistein induces the metastasis suppressor kangai-1 which mediates its anti-invasive effects in TRAMP cancer cells. Biochem Biophys Res Commun 361, 169-175.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 169-175
    • El Touny, L.H.1    Banerjee, P.P.2
  • 171
    • 33644822532 scopus 로고    scopus 로고
    • The invasive behaviour of prostatic cancer cells is suppressed by inhibitors of tyrosine kinase
    • Skogseth H, Larsson E & Halgunset J (2006) The invasive behaviour of prostatic cancer cells is suppressed by inhibitors of tyrosine kinase. Apmis 114, 61-66.
    • (2006) Apmis , vol.114 , pp. 61-66
    • Skogseth, H.1    Larsson, E.2    Halgunset, J.3
  • 172
    • 33846188115 scopus 로고    scopus 로고
    • Influence of genistein isoflavone on matrix metalloproteinase-2 expression in prostate cancer cells
    • Kumi-Diaka JK, Hassanhi M, Merchant K & Horman V (2006) Influence of genistein isoflavone on matrix metalloproteinase-2 expression in prostate cancer cells. J Med Food 9, 491-497.
    • (2006) J Med Food , vol.9 , pp. 491-497
    • Kumi-Diaka, J.K.1    Hassanhi, M.2    Merchant, K.3    Horman, V.4
  • 173
    • 33747618245 scopus 로고    scopus 로고
    • Genistein inhibits matrix metallo-proteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway
    • Xu L & Bergan RC (2006) Genistein inhibits matrix metallo-proteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway. Mol Pharmacol 70, 869-877.
    • (2006) Mol Pharmacol , vol.70 , pp. 869-877
    • Xu, L.1    Bergan, R.C.2
  • 174
    • 17144426480 scopus 로고    scopus 로고
    • Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells
    • Huang XK, Chen S, Xu L, Liu YQ, Deb DK, Platanias LC & Bergan RC (2005) Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. Cancer Res 65, 3470-3478.
    • (2005) Cancer Res , vol.65 , pp. 3470-3478
    • Huang, X.K.1    Chen, S.2    Xu, L.3    Liu, Y.Q.4    Deb, D.K.5    Platanias, L.C.6    Bergan, R.C.7
  • 175
    • 18344395406 scopus 로고    scopus 로고
    • Dietary genistein improves survival and reduces expression of osteopontin in the prostate of transgenic mice with prostatic adenocarcinoma (TRAMP)
    • Mentor-Marcel R, Lamartiniere CA, Eltoum IA, Greenberg NM & Elgavish A (2005) Dietary genistein improves survival and reduces expression of osteopontin in the prostate of transgenic mice with prostatic adenocarcinoma (TRAMP). J Nutr 135, 989-995.
    • (2005) J Nutr , vol.135 , pp. 989-995
    • Mentor-Marcel, R.1    Lamartiniere, C.A.2    Eltoum, I.A.3    Greenberg, N.M.4    Elgavish, A.5
  • 176
    • 0027194978 scopus 로고
    • Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation
    • Peterson G & Barnes S (1993) Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation. Prostate 22, 335-345.
    • (1993) Prostate , vol.22 , pp. 335-345
    • Peterson, G.1    Barnes, S.2
  • 177
    • 0038606063 scopus 로고    scopus 로고
    • Tomato and soy polyphenols reduce insulin-like growth factor-I-stimulated rat prostate cancer cell proliferation and apoptotic resistance in vitro via inhibition of intracellular signaling pathways involving tyrosine kinase
    • Wang S, DeGroff VL & Clinton SK (2003) Tomato and soy polyphenols reduce insulin-like growth factor-I-stimulated rat prostate cancer cell proliferation and apoptotic resistance in vitro via inhibition of intracellular signaling pathways involving tyrosine kinase. J Nutr 133, 2367-2376.
    • (2003) J Nutr , vol.133 , pp. 2367-2376
    • Wang, S.1    DeGroff, V.L.2    Clinton, S.K.3
  • 179
    • 0031880755 scopus 로고    scopus 로고
    • Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate
    • Dalu A, Haskell JF, Coward L & Lamartiniere CA (1998) Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate. Prostate 37, 36-43.
    • (1998) Prostate , vol.37 , pp. 36-43
    • Dalu, A.1    Haskell, J.F.2    Coward, L.3    Lamartiniere, C.A.4
  • 180
    • 2442473892 scopus 로고    scopus 로고
    • Genistein alters growth factor signaling in transgenic prostate model (TRAMP)
    • Wang J, Eltoum IE & Lamartiniere CA (2004) Genistein alters growth factor signaling in transgenic prostate model (TRAMP). Mol Cell Endocrinol 219, 171-180.
    • (2004) Mol Cell Endocrinol , vol.219 , pp. 171-180
    • Wang, J.1    Eltoum, I.E.2    Lamartiniere, C.A.3
  • 181
    • 0031783444 scopus 로고    scopus 로고
    • Prepubertal genistein treatment modulates TGF-alpha, EGF and EGF-receptor mRNAs and proteins in the rat mammary gland
    • Brown NM, Wang J, Cotroneo MS, Zhao YX & Lamartiniere CA (1998) Prepubertal genistein treatment modulates TGF-alpha, EGF and EGF-receptor mRNAs and proteins in the rat mammary gland. Mol Cell Endocrinol 144, 149-165.
    • (1998) Mol Cell Endocrinol , vol.144 , pp. 149-165
    • Brown, N.M.1    Wang, J.2    Cotroneo, M.S.3    Zhao, Y.X.4    Lamartiniere, C.A.5
  • 184
    • 2442497058 scopus 로고    scopus 로고
    • Genistein enhances insulin-like growth factor signaling pathway in human breast cancer (MCF-7) cells
    • Chen WF & Wong MS (2004) Genistein enhances insulin-like growth factor signaling pathway in human breast cancer (MCF-7) cells. J Clin Endocrinol Metab 89, 2351-2359.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2351-2359
    • Chen, W.F.1    Wong, M.S.2
  • 185
    • 0035180790 scopus 로고    scopus 로고
    • Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats
    • Aukema HM & Housini I (2001) Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats. Kidney Int 59, 52-61.
    • (2001) Kidney Int , vol.59 , pp. 52-61
    • Aukema, H.M.1    Housini, I.2
  • 186
    • 0043013278 scopus 로고    scopus 로고
    • Dietary soy and fats in relation to serum insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 levels in premenopausal Japanese women
    • Nagata C, Shimizu H, Takami R, Hayashi M, Takeda N & Yasuda K (2003) Dietary soy and fats in relation to serum insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 levels in premenopausal Japanese women. Nutr Cancer 45, 185-189.
    • (2003) Nutr Cancer , vol.45 , pp. 185-189
    • Nagata, C.1    Shimizu, H.2    Takami, R.3    Hayashi, M.4    Takeda, N.5    Yasuda, K.6
  • 187
    • 0036846587 scopus 로고    scopus 로고
    • The associations of diet with serum insulin-like growth factor I and its main binding proteins in 292 women meat-eaters, vegetarians, and vegans
    • Allen NE, Appleby PN, Davey GK, Kaaks R, Rinaldi S & Key TJ (2002) The associations of diet with serum insulin-like growth factor I and its main binding proteins in 292 women meat-eaters, vegetarians, and vegans. Cancer Epidemiol Biomarkers Prev 11, 1441-1448.
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 1441-1448
    • Allen, N.E.1    Appleby, P.N.2    Davey, G.K.3    Kaaks, R.4    Rinaldi, S.5    Key, T.J.6
  • 189
    • 0037339004 scopus 로고    scopus 로고
    • Soy protein has a greater effect on bone in postmenopausal women not on hormone replacement therapy, as evidenced by reducing bone resorption and urinary calcium excretion
    • Arjmandi BH, Khalil DA, Smith BJ, Lucas EA, Juma S, Payton ME & Wild RA (2003) Soy protein has a greater effect on bone in postmenopausal women not on hormone replacement therapy, as evidenced by reducing bone resorption and urinary calcium excretion. J Clin Endocrinol Metab 88, 1048-1054.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1048-1054
    • Arjmandi, B.H.1    Khalil, D.A.2    Smith, B.J.3    Lucas, E.A.4    Juma, S.5    Payton, M.E.6    Wild, R.A.7
  • 192
    • 0041525338 scopus 로고    scopus 로고
    • Determinants of circulating insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations in a cohort of Singapore men and women
    • Probst-Hensch NM, Wang H, Gob VH, Seow A, Lee HP & Yu MC (2003) Determinants of circulating insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations in a cohort of Singapore men and women. Cancer Epidemiol Biomarkers Prev 12 739-746.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 739-746
    • Probst-Hensch, N.M.1    Wang, H.2    Gob, V.H.3    Seow, A.4    Lee, H.P.5    Yu, M.C.6
  • 193
    • 0036712564 scopus 로고    scopus 로고
    • Soy protein supplementation increases serum insulin-like growth factor-I in young and old men but does not affect markers of bone metabolism
    • Khalil DA, Lucas EA, Juma S, Smith BJ, Payton ME & Arjmandi BH (2002) Soy protein supplementation increases serum insulin-like growth factor-I in young and old men but does not affect markers of bone metabolism. J Nutr 132, 2605-2608.
    • (2002) J Nutr , vol.132 , pp. 2605-2608
    • Khalil, D.A.1    Lucas, E.A.2    Juma, S.3    Smith, B.J.4    Payton, M.E.5    Arjmandi, B.H.6
  • 194
    • 0037995325 scopus 로고    scopus 로고
    • Soy Isoflavones do not modulate circulating insulin-like growth factor concentrations in an older population in an intervention trial
    • Adams KF, Newton KM, Chen C, Emerson SS, Potter JD, White E & Lampe JW (2003) Soy Isoflavones do not modulate circulating insulin-like growth factor concentrations in an older population in an intervention trial. J Nutr 133, 1316-1319.
    • (2003) J Nutr , vol.133 , pp. 1316-1319
    • Adams, K.F.1    Newton, K.M.2    Chen, C.3    Emerson, S.S.4    Potter, J.D.5    White, E.6    Lampe, J.W.7
  • 196
    • 33644512054 scopus 로고    scopus 로고
    • Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells
    • Jagadeesh S, Kyo S & Banerjee PP (2006) Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells. Cancer Res 66, 2107-2115.
    • (2006) Cancer Res , vol.66 , pp. 2107-2115
    • Jagadeesh, S.1    Kyo, S.2    Banerjee, P.P.3
  • 197
    • 34547092913 scopus 로고    scopus 로고
    • Akt/GSK3 pathway as a target in genistein-induced inhibition of TRAMP prostate cancer progression towards a poorly differentiated phenotype
    • El Touny LH & Banerjee PP (2007) Akt/GSK3 pathway as a target in genistein-induced inhibition of TRAMP prostate cancer progression towards a poorly differentiated phenotype. Carcinogenesis.
    • (2007) Carcinogenesis
    • El Touny, L.H.1    Banerjee, P.P.2
  • 198
    • 0037027752 scopus 로고    scopus 로고
    • Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein
    • Li Y & Sarkar FH (2002) Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein. Cancer Lett 186 157-164.
    • (2002) Cancer Lett , vol.186 , pp. 157-164
    • Li, Y.1    Sarkar, F.H.2
  • 199
    • 0041589149 scopus 로고    scopus 로고
    • Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells
    • Gong L, Li Y, Nedeljkovic-Kurepa A & Sarkar FH (2003) Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells. Oncogene 22, 4702-4709.
    • (2003) Oncogene , vol.22 , pp. 4702-4709
    • Gong, L.1    Li, Y.2    Nedeljkovic-Kurepa, A.3    Sarkar, F.H.4
  • 200
    • 0036898130 scopus 로고    scopus 로고
    • Gene expression profiles of genistein-treated PC3 prostate cancer cells
    • Li Y & Sarkar FH (2002) Gene expression profiles of genistein-treated PC3 prostate cancer cells. J Nutr 132, 3623-3631.
    • (2002) J Nutr , vol.132 , pp. 3623-3631
    • Li, Y.1    Sarkar, F.H.2
  • 201
    • 0033509354 scopus 로고
    • Genistein inhibits NF-kappa B activation in prostate cancer cells
    • Davis JN, Kobuk O & Sarkar FH (1990) Genistein inhibits NF-kappa B activation in prostate cancer cells. Nutr Cancer 35, 167-174.
    • (1990) Nutr Cancer , vol.35 , pp. 167-174
    • Davis, J.N.1    Kobuk, O.2    Sarkar, F.H.3
  • 202
    • 33646424342 scopus 로고    scopus 로고
    • Attenuation of mitogen- and stress-activatod protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity
    • Vanden Berghe W, Dijsselbloem N, Vermeulen L, Ndlovu N, Boone E & Haegeman G (2006) Attenuation of mitogen- and stress-activatod protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity. Cancer Res 66, 4852-4862.
    • (2006) Cancer Res , vol.66 , pp. 4852-4862
    • Vanden Berghe, W.1    Dijsselbloem, N.2    Vermeulen, L.3    Ndlovu, N.4    Boone, E.5    Haegeman, G.6
  • 203
    • 33845670737 scopus 로고    scopus 로고
    • Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: Involvement of estrogen receptors, ERK1/2, and NF kappa B
    • Borras C, Gambini J, Gomez-Cabrera MC, Sastre J, Pallardo FV, Mann GE & Vina J (2006) Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: Involvement of estrogen receptors, ERK1/2, and NF kappa B. FASEB J 20, 2136.
    • (2006) FASEB J , vol.20 , pp. 2136
    • Borras, C.1    Gambini, J.2    Gomez-Cabrera, M.C.3    Sastre, J.4    Pallardo, F.V.5    Mann, G.E.6    Vina, J.7
  • 204
    • 32644474034 scopus 로고    scopus 로고
    • Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways
    • Wang XY, Clubbs EA & Bomser JA (2006) Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways. J Nutr Biochem 17 204-210.
    • (2006) J Nutr Biochem , vol.17 , pp. 204-210
    • Wang, X.Y.1    Clubbs, E.A.2    Bomser, J.A.3
  • 205
    • 34447281085 scopus 로고    scopus 로고
    • Glycitein activates extracellular signal-regulated kinase via vascular endothelial growth factor receptor signaling in nontumorigenic (RWPE-1) prostate epithelial cells
    • Clubbs EA & Bomser JA (2007) Glycitein activates extracellular signal-regulated kinase via vascular endothelial growth factor receptor signaling in nontumorigenic (RWPE-1) prostate epithelial cells. J Nutr Biochem 18, 525-532.
    • (2007) J Nutr Biochem , vol.18 , pp. 525-532
    • Clubbs, E.A.1    Bomser, J.A.2
  • 206
    • 0037130887 scopus 로고    scopus 로고
    • Cancer incidence in BRCA1 mutation carriers
    • Thompson D & Easton DF (2002) Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst 94, 1358-1365.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1358-1365
    • Thompson, D.1    Easton, D.F.2
  • 207
    • 33751278712 scopus 로고    scopus 로고
    • Cellular functions of the BRCA tumour-suppressor proteins
    • Boulton SJ (2006) Cellular functions of the BRCA tumour-suppressor proteins. Biochem Soc Trans 34, 633-645.
    • (2006) Biochem Soc Trans , vol.34 , pp. 633-645
    • Boulton, S.J.1
  • 209
    • 32544442522 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells
    • Fan S, Meng Q, Auborn K, Carter T & Rosen EM (2006) BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells. Br J Cancer 94, 407-426.
    • (2006) Br J Cancer , vol.94 , pp. 407-426
    • Fan, S.1    Meng, Q.2    Auborn, K.3    Carter, T.4    Rosen, E.M.5
  • 211
    • 33646512624 scopus 로고    scopus 로고
    • Antioxidant activity of isoflavones and their major metabolites using different in vitro assays
    • Rufer CE & Kulling SE (2006) Antioxidant activity of isoflavones and their major metabolites using different in vitro assays. J Agric Food Chem 54, 2926-2931.
    • (2006) J Agric Food Chem , vol.54 , pp. 2926-2931
    • Rufer, C.E.1    Kulling, S.E.2
  • 212
    • 0027179061 scopus 로고
    • Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein
    • Wei H, Wei L, Frenkel K, Bowen R & Barnes S (1993) Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr Cancer 20, 1-12.
    • (1993) Nutr Cancer , vol.20 , pp. 1-12
    • Wei, H.1    Wei, L.2    Frenkel, K.3    Bowen, R.4    Barnes, S.5
  • 214
    • 33750437435 scopus 로고    scopus 로고
    • Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress
    • Raschke M, Rowland IR, Magee PJ & Pool-Zobel BL (2006) Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress. Carcinogenesis 27, 2322-2330.
    • (2006) Carcinogenesis , vol.27 , pp. 2322-2330
    • Raschke, M.1    Rowland, I.R.2    Magee, P.J.3    Pool-Zobel, B.L.4
  • 215
    • 18444386810 scopus 로고    scopus 로고
    • Soy isoflavone supplementation elevates erythrocyte superoxide dismutase, but not plasma ceruloplasmin in postmenopausal breast cancer survivors
    • DiSilvestro RA, Goodman J, Dy E & Lavalle G (2005) Soy isoflavone supplementation elevates erythrocyte superoxide dismutase, but not plasma ceruloplasmin in postmenopausal breast cancer survivors. Breast Cancer Res Treat 89, 251-255.
    • (2005) Breast Cancer Res Treat , vol.89 , pp. 251-255
    • DiSilvestro, R.A.1    Goodman, J.2    Dy, E.3    Lavalle, G.4
  • 216
    • 0035212383 scopus 로고    scopus 로고
    • Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats
    • Rowlands JC, He L, Hakkak R, Ronis MJ & Badger TM (2001) Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats. J Nutr 131, 3281-3287.
    • (2001) J Nutr , vol.131 , pp. 3281-3287
    • Rowlands, J.C.1    He, L.2    Hakkak, R.3    Ronis, M.J.4    Badger, T.M.5
  • 217
    • 0041561001 scopus 로고    scopus 로고
    • A potential protective mechanism of soya isoflavones against 7,12-dimethylbenz [a]anthracene tumour initiatio n
    • Chan HY & Leung LK (2003) A potential protective mechanism of soya isoflavones against 7,12-dimethylbenz [a]anthracene tumour initiatio n. Br J Nutr 90, 457-465.
    • (2003) Br J Nutr , vol.90 , pp. 457-465
    • Chan, H.Y.1    Leung, L.K.2
  • 218
    • 0042510053 scopus 로고    scopus 로고
    • Effect of daidzein on CYP1A2 activity and pharmacokinetics of theophylline in healthy volunteers
    • Peng WX, Li HD & Zhou HH (2003) Effect of daidzein on CYP1A2 activity and pharmacokinetics of theophylline in healthy volunteers. Eur J Clin Pharmacol 59, 237-241.
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 237-241
    • Peng, W.X.1    Li, H.D.2    Zhou, H.H.3
  • 219
    • 34047166461 scopus 로고    scopus 로고
    • Genistein protects human mammary epithelial cells from benzo(a pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S transferase system
    • Steiner C, Peters WH, Gallagher EP, Magee P, Rowland I & Pool-Zobel BL (2007) Genistein protects human mammary epithelial cells from benzo(a pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S transferase system. Carcinogenesis 28, 738-748.
    • (2007) Carcinogenesis , vol.28 , pp. 738-748
    • Steiner, C.1    Peters, W.H.2    Gallagher, E.P.3    Magee, P.4    Rowland, I.5    Pool-Zobel, B.L.6
  • 220
    • 12744280974 scopus 로고    scopus 로고
    • Differential induction of quinone reductase by phytoestrogens and protection against oestrogen-induced DNA damage
    • Bianco NR, Chaplin LJ & Montano MM (2005) Differential induction of quinone reductase by phytoestrogens and protection against oestrogen-induced DNA damage. Biochem J 385, 279-287.
    • (2005) Biochem J , vol.385 , pp. 279-287
    • Bianco, N.R.1    Chaplin, L.J.2    Montano, M.M.3
  • 221
    • 0037728678 scopus 로고    scopus 로고
    • Genistein inhibits vitamin D hydroxylases CYP24 and CYP27B1 expression in prostate cells
    • Farhan H, Wahala K & Cross HS (2003) Genistein inhibits vitamin D hydroxylases CYP24 and CYP27B1 expression in prostate cells. J Steroid Biochem Mol Biol 84, 423-429.
    • (2003) J Steroid Biochem Mol Biol , vol.84 , pp. 423-429
    • Farhan, H.1    Wahala, K.2    Cross, H.S.3
  • 222
    • 2442598406 scopus 로고    scopus 로고
    • Phytoestrogens and vitamin D metabolism: A new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas
    • Cross HS, Kallay E, Lechner D, Gerdenitsch W, Adlercreutz H & Armbrecht HJ (2004) Phytoestrogens and vitamin D metabolism: A new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas. J Nutr 134, 1207S-1212S.
    • (2004) J Nutr , vol.134
    • Cross, H.S.1    Kallay, E.2    Lechner, D.3    Gerdenitsch, W.4    Adlercreutz, H.5    Armbrecht, H.J.6
  • 225
    • 13844255752 scopus 로고    scopus 로고
    • Health-related interactions of phytochemicals
    • Lila MA & Raskin I (2005) Health-related interactions of phytochemicals. J Food Sci 70, R20-R27.
    • (2005) J Food Sci , vol.70
    • Lila, M.A.1    Raskin, I.2
  • 226
    • 0035668047 scopus 로고    scopus 로고
    • Cross-talk among estrogen receptor, epidermal growth factor, and insulin-like growth factor signaling in breast cancer
    • Lee AV, Cui XJ & Oesterreich S (2001) Cross-talk among estrogen receptor, epidermal growth factor, and insulin-like growth factor signaling in breast cancer. Clin Cancer Res 7, 4429S-4435S.
    • (2001) Clin Cancer Res , vol.7
    • Lee, A.V.1    Cui, X.J.2    Oesterreich, S.3
  • 227
    • 0037064106 scopus 로고    scopus 로고
    • Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
    • Ueda T, Mawji NR, Bruchovsky N & Sadar MD, (2002) Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. J Biol Chem 277, 38087-38094.
    • (2002) J Biol Chem , vol.277 , pp. 38087-38094
    • Ueda, T.1    Mawji, N.R.2    Bruchovsky, N.3    Sadar, M.D.4
  • 229
    • 9244221653 scopus 로고    scopus 로고
    • Targeting Multiple signaling pathways as a strategy for managing prostate cancer: Multifocal signal modulation therapy
    • McCarty MF (2004) Targeting Multiple signaling pathways as a strategy for managing prostate cancer: Multifocal signal modulation therapy. Integr Cancer Ther 3, 349-380.
    • (2004) Integr Cancer Ther , vol.3 , pp. 349-380
    • McCarty, M.F.1
  • 230
    • 0037937417 scopus 로고    scopus 로고
    • Interactions between insulin-like growth factor estrogen and signaling pathways in human breast tumor cells
    • Hamelers IHL & Steenbergh PH (2003) Interactions between insulin-like growth factor estrogen and signaling pathways in human breast tumor cells. Endocr Relat Cancer 10, 331-345.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 331-345
    • Hamelers, I.H.L.1    Steenbergh, P.H.2
  • 231
    • 0037200657 scopus 로고    scopus 로고
    • Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gaminal in MDA-MB-231 and MCF-7 breast cancer cells
    • Wang X & Kilgore MW (2002) Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gaminal in MDA-MB-231 and MCF-7 breast cancer cells. Mol Cell Endocrinol 194, 123-133.
    • (2002) Mol Cell Endocrinol , vol.194 , pp. 123-133
    • Wang, X.1    Kilgore, M.W.2
  • 232
    • 24344455975 scopus 로고    scopus 로고
    • Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells
    • Bonofiglio D, Gabriele S, Aquila S, Catalano S, Gentile M, Middea E, Giordano F & Ando S (2005) Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells. Clin Cancer Res 11, 6139-6147.
    • (2005) Clin Cancer Res , vol.11 , pp. 6139-6147
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3    Catalano, S.4    Gentile, M.5    Middea, E.6    Giordano, F.7    Ando, S.8
  • 233
    • 33750475959 scopus 로고    scopus 로고
    • Cross-talk between nuclear receptors and nuclear factor kappa B
    • De Bosscher K, Vanden Berghe W & Haegeman G (2006) Cross-talk between nuclear receptors and nuclear factor kappa B. Oncogene 25, 6868-6886.
    • (2006) Oncogene , vol.25 , pp. 6868-6886
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 234
    • 1642499403 scopus 로고    scopus 로고
    • Suppression of PTEN expression by NF-kappa B prevents apoptosis
    • Vasudevan KM, Gurumurthy S & Rangnekar VM (2004) Suppression of PTEN expression by NF-kappa B prevents apoptosis. Mol Cell Biol 24 1007-1021.
    • (2004) Mol Cell Biol , vol.24 , pp. 1007-1021
    • Vasudevan, K.M.1    Gurumurthy, S.2    Rangnekar, V.M.3
  • 236
    • 14844288020 scopus 로고    scopus 로고
    • Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray
    • Ise R, Han D, Takahashi Y, Terasaka S, Inoue A, Tanji M & Kiyama R (2005) Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray. FEBS Lett 579, 1732-1740.
    • (2005) FEBS Lett , vol.579 , pp. 1732-1740
    • Ise, R.1    Han, D.2    Takahashi, Y.3    Terasaka, S.4    Inoue, A.5    Tanji, M.6    Kiyama, R.7
  • 238
    • 0035996075 scopus 로고    scopus 로고
    • Naciff JM, Jump ML, Torontali SM, Carr GJ, Tiesman JP, Overmann GJ & Daston GP (2002) Gene expression profile induced by 17alpha-ethynyl estradiol, bisphenol A, and genistein in the developing female reproductive system of the rat. Toxicol Sci 68, 184-199.
    • Naciff JM, Jump ML, Torontali SM, Carr GJ, Tiesman JP, Overmann GJ & Daston GP (2002) Gene expression profile induced by 17alpha-ethynyl estradiol, bisphenol A, and genistein in the developing female reproductive system of the rat. Toxicol Sci 68, 184-199.
  • 240
    • 3342931244 scopus 로고    scopus 로고
    • Toxicogenomic approach to endocrine disrupters: Identification of a transcript profile characteristic of chemicals with estrogenic activity
    • Naciff JM & Daston GP (2004) Toxicogenomic approach to endocrine disrupters: Identification of a transcript profile characteristic of chemicals with estrogenic activity. Toxicol Pathol 32, 59-70.
    • (2004) Toxicol Pathol , vol.32 , pp. 59-70
    • Naciff, J.M.1    Daston, G.P.2
  • 242
    • 33747893350 scopus 로고    scopus 로고
    • Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells
    • Buterin T, Koch C & Naegeli H (2006) Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells. Carcinogenesis 27, 1567-1578.
    • (2006) Carcinogenesis , vol.27 , pp. 1567-1578
    • Buterin, T.1    Koch, C.2    Naegeli, H.3
  • 244
    • 28844488763 scopus 로고    scopus 로고
    • cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cells
    • York TP, Plymate SR, Nelson PS, Eaves LJ, Webb HD & Ware JL (2005) cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cells. Mol Carcinog 44, 242-251.
    • (2005) Mol Carcinog , vol.44 , pp. 242-251
    • York, T.P.1    Plymate, S.R.2    Nelson, P.S.3    Eaves, L.J.4    Webb, H.D.5    Ware, J.L.6
  • 245
    • 8344263222 scopus 로고    scopus 로고
    • Gene expression profiles in mammary gland of male rats treated with genstein and methoxychlor
    • You L & Bartolucci EJ (2004) Gene expression profiles in mammary gland of male rats treated with genstein and methoxychlor. Environ Toxical Pharmacol 18, 161-172.
    • (2004) Environ Toxical Pharmacol , vol.18 , pp. 161-172
    • You, L.1    Bartolucci, E.J.2
  • 246
    • 5044226337 scopus 로고    scopus 로고
    • Using DNA microarray analyses to elucidate the effects of genistein in androgen-responsive prostate cancer cells: Identification of novel targets
    • Takahashi Y, Lavigne JA, Hursting SD, Chandramouli GVR, Perkins SN, Barrett JC & Wang TTY (2004) Using DNA microarray analyses to elucidate the effects of genistein in androgen-responsive prostate cancer cells: identification of novel targets. Mol Carcinog 41, 108-119.
    • (2004) Mol Carcinog , vol.41 , pp. 108-119
    • Takahashi, Y.1    Lavigne, J.A.2    Hursting, S.D.3    Chandramouli, G.V.R.4    Perkins, S.N.5    Barrett, J.C.6    Wang, T.T.Y.7
  • 247
    • 33845403873 scopus 로고    scopus 로고
    • Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: A comparison study using DNA microarray
    • Takahashi Y, Lavigne JA, Hursting SD, Chandramouli GVR, Perkins SN, Kim YS & Wang TTY (2006) Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: A comparison study using DNA microarray. Mol Carcinog, 45, 943-956.
    • (2006) Mol Carcinog , vol.45 , pp. 943-956
    • Takahashi, Y.1    Lavigne, J.A.2    Hursting, S.D.3    Chandramouli, G.V.R.4    Perkins, S.N.5    Kim, Y.S.6    Wang, T.T.Y.7
  • 248
    • 31044456716 scopus 로고    scopus 로고
    • Genistein affects androgen-responsive genes through both androgen- and estrogen-induced signaling pathways
    • Takahashi Y, Hursting SD, Perkins SN, Wang TC & Wang TTY (2006) Genistein affects androgen-responsive genes through both androgen- and estrogen-induced signaling pathways. Mol Carcinog 45, 18-25.
    • (2006) Mol Carcinog , vol.45 , pp. 18-25
    • Takahashi, Y.1    Hursting, S.D.2    Perkins, S.N.3    Wang, T.C.4    Wang, T.T.Y.5
  • 252
    • 31544463520 scopus 로고    scopus 로고
    • Soy isoflavones alter expression of genes associated with cancer progression, including interleukin-8, in androgen-independent PC-3 human prostate cancer cells
    • Handayani R, Rice L, Cui Y, Medrano TA, Samedi VG, Baker HV, Szabo NJ & Shiverick KT (2006) Soy isoflavones alter expression of genes associated with cancer progression, including interleukin-8, in androgen-independent PC-3 human prostate cancer cells. J Nutr 136, 75-82.
    • (2006) J Nutr , vol.136 , pp. 75-82
    • Handayani, R.1    Rice, L.2    Cui, Y.3    Medrano, T.A.4    Samedi, V.G.5    Baker, H.V.6    Szabo, N.J.7    Shiverick, K.T.8
  • 253
    • 31544446840 scopus 로고    scopus 로고
    • Chemo-prevention of breast cancer, proteomic discovery of genistein action in the rat mammary gland
    • Rowell C, Carpenter DM & Lamartiniere CA (2005) Chemo-prevention of breast cancer, proteomic discovery of genistein action in the rat mammary gland. J Nutr 135, 2953S-2959S.
    • (2005) J Nutr , vol.135
    • Rowell, C.1    Carpenter, D.M.2    Lamartiniere, C.A.3
  • 255
    • 0344493931 scopus 로고    scopus 로고
    • Application of biofluid H-1 nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile
    • Solanky KS, Bailey NJC, Beckwith-Hall BM, Davis A, Bingham S, Holmes E, Nicholson JK & Cassidy A (2003) Application of biofluid H-1 nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile. Anal Biochem 323, 197-204.
    • (2003) Anal Biochem , vol.323 , pp. 197-204
    • Solanky, K.S.1    Bailey, N.J.C.2    Beckwith-Hall, B.M.3    Davis, A.4    Bingham, S.5    Holmes, E.6    Nicholson, J.K.7    Cassidy, A.8
  • 257
    • 18144384816 scopus 로고    scopus 로고
    • Targeting epigenetic regulatory mechanisms in cancer chemoprevention
    • Fay JR, Crowell JA & Kopelovich L (2005) Targeting epigenetic regulatory mechanisms in cancer chemoprevention. Expert Opin Ther Targets 9, 315-328.
    • (2005) Expert Opin Ther Targets , vol.9 , pp. 315-328
    • Fay, J.R.1    Crowell, J.A.2    Kopelovich, L.3
  • 258
    • 33750533592 scopus 로고    scopus 로고
    • Epigenetic regulation of nuclear steroid receptors
    • Leader JE, Wang C, Fu M & Pestell RG (2006) Epigenetic regulation of nuclear steroid receptors. Biochem Pharmacol 72, 1589-1596.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1589-1596
    • Leader, J.E.1    Wang, C.2    Fu, M.3    Pestell, R.G.4
  • 261
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK & Yang CS (2005) Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11 7033-7041.
    • (2005) Clin Cancer Res , vol.11 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 264
    • 0033233309 scopus 로고    scopus 로고
    • Wong CK & Keung WM (1999) Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1. 145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): characterization and its inhibition by isoflavones. J Steroid Biochem Mol Biol 71, 191-202.
    • Wong CK & Keung WM (1999) Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1. 145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): characterization and its inhibition by isoflavones. J Steroid Biochem Mol Biol 71, 191-202.
  • 265
    • 0037087689 scopus 로고    scopus 로고
    • Structure-activity relationships for inhibition of human 5 alpha-reductases by polyphenols
    • Hiipakka RA, Zhang HZ, Dai W, Dai Q & Liao ST (2002) Structure-activity relationships for inhibition of human 5 alpha-reductases by polyphenols. Biochem Pharmacol 63, 1165-1176.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1165-1176
    • Hiipakka, R.A.1    Zhang, H.Z.2    Dai, W.3    Dai, Q.4    Liao, S.T.5
  • 266
    • 0023612656 scopus 로고
    • Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG)
    • Adlercreutz H, Hockerstedt K, Bannwart C, Bloigu S, Hamalainen E, Fotsis T & Ollus A (1987) Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG). J Steroid Biochem 27, 1135-1144.
    • (1987) J Steroid Biochem , vol.27 , pp. 1135-1144
    • Adlercreutz, H.1    Hockerstedt, K.2    Bannwart, C.3    Bloigu, S.4    Hamalainen, E.5    Fotsis, T.6    Ollus, A.7
  • 270
    • 33745296888 scopus 로고    scopus 로고
    • The effects of short-term oral phytoestrogen supplementation on the hypothalamic-pituitary-testicular axis in prostate cancer patients
    • Rannikko A, Petas A, Raivio T, Janne OA, Rannikko S & Adlercreutz H (2006) The effects of short-term oral phytoestrogen supplementation on the hypothalamic-pituitary-testicular axis in prostate cancer patients. Prostate 66, 1086-1091.
    • (2006) Prostate , vol.66 , pp. 1086-1091
    • Rannikko, A.1    Petas, A.2    Raivio, T.3    Janne, O.A.4    Rannikko, S.5    Adlercreutz, H.6
  • 271
    • 0032054451 scopus 로고    scopus 로고
    • Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21(WAF1/CIP1) induction, G(2)/M arrest, and apoptosis
    • Shao ZM, Alpaugh ML, Fontana JA & Barsky SH (1998) Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21(WAF1/CIP1) induction, G(2)/M arrest, and apoptosis. J Cell Biochem 69, 44-54.
    • (1998) J Cell Biochem , vol.69 , pp. 44-54
    • Shao, Z.M.1    Alpaugh, M.L.2    Fontana, J.A.3    Barsky, S.H.4
  • 272
    • 0036781426 scopus 로고    scopus 로고
    • Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells
    • Katdare M, Osborne M & Telang NT (2002) Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells. Int J Oncol 21, 809-815.
    • (2002) Int J Oncol , vol.21 , pp. 809-815
    • Katdare, M.1    Osborne, M.2    Telang, N.T.3
  • 273
    • 0035992417 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway
    • Li Y & Sarkar FH (2002) Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res 8, 2369-2377.
    • (2002) Clin Cancer Res , vol.8 , pp. 2369-2377
    • Li, Y.1    Sarkar, F.H.2
  • 274
    • 33646424342 scopus 로고    scopus 로고
    • Attenuation of mitogen-and stress-activated protein kinase-1-driven nuclear factor-kappa B gene expression by soy isoflavones does not require estrogenic activity
    • Berghe WV, Dijsselbloem N, Vermeulen L, Ndlovu MN, Boone E & Haegeman G (2006) Attenuation of mitogen-and stress-activated protein kinase-1-driven nuclear factor-kappa B gene expression by soy isoflavones does not require estrogenic activity. Cancer Res 66 4852-4862.
    • (2006) Cancer Res , vol.66 , pp. 4852-4862
    • Berghe, W.V.1    Dijsselbloem, N.2    Vermeulen, L.3    Ndlovu, M.N.4    Boone, E.5    Haegeman, G.6
  • 275
    • 0036132773 scopus 로고    scopus 로고
    • Effect of dietary administration of genistein, nonylphenol or ethinyl estradiol on hepatic testosterone metabolism, cytochrome P-450 enzymes, and estrogen receptor alpha expression
    • Laurenzana EM, Weis CC, Bryant CW, Newbold R & Delclos KB (2002) Effect of dietary administration of genistein, nonylphenol or ethinyl estradiol on hepatic testosterone metabolism, cytochrome P-450 enzymes, and estrogen receptor alpha expression. Food Chem Toxicol 40, 53-63.
    • (2002) Food Chem Toxicol , vol.40 , pp. 53-63
    • Laurenzana, E.M.1    Weis, C.C.2    Bryant, C.W.3    Newbold, R.4    Delclos, K.B.5
  • 276
    • 5744248613 scopus 로고    scopus 로고
    • Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions from healthy human mammary tissues: Implications for catechol estrogen-induced DNA damage
    • van Duursen MB, Sanderson JT, de Jong PC, Kraaij M & van den Berg M (2004) Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions from healthy human mammary tissues: implications for catechol estrogen-induced DNA damage. Toxicol Sci 81, 316-324.
    • (2004) Toxicol Sci , vol.81 , pp. 316-324
    • van Duursen, M.B.1    Sanderson, J.T.2    de Jong, P.C.3    Kraaij, M.4    van den Berg, M.5
  • 277
    • 0032881196 scopus 로고    scopus 로고
    • Soy induces phase II enzymes but does not inhibit dimethylbenz[a]anthracene-induced carcinogenesis in female rats
    • Appelt LC & Reicks MM (1999) Soy induces phase II enzymes but does not inhibit dimethylbenz[a]anthracene-induced carcinogenesis in female rats. J Nutr 129, 1820-1826.
    • (1999) J Nutr , vol.129 , pp. 1820-1826
    • Appelt, L.C.1    Reicks, M.M.2
  • 278
    • 0030022005 scopus 로고    scopus 로고
    • Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention
    • Eaton EA, Walle UK, Lewis AJ, Hudson T, Wilson AA & Walle T (1996) Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention. Drug Metab Dispos 24, 232-237.
    • (1996) Drug Metab Dispos , vol.24 , pp. 232-237
    • Eaton, E.A.1    Walle, U.K.2    Lewis, A.J.3    Hudson, T.4    Wilson, A.A.5    Walle, T.6


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