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Volumn 65, Issue 8, 2005, Pages 3470-3478

Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; GELATINASE A; GENISTEIN; MATRIX METALLOPROTEINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 17144426480     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-2807     Document Type: Article
Times cited : (200)

References (50)
  • 1
    • 0024514225 scopus 로고
    • A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii
    • Severson RK, Nomura AM, Grove JS, Stemmermann GN. A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii. Cancer Res 1989;49:1857-60.
    • (1989) Cancer Res , vol.49 , pp. 1857-1860
    • Severson, R.K.1    Nomura, A.M.2    Grove, J.S.3    Stemmermann, G.N.4
  • 2
    • 0025769201 scopus 로고
    • Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County
    • Shimizu H, Ross RK, Bernstein L, et al. Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County. Br J Cancer 1991;63:963-6.
    • (1991) Br J Cancer , vol.63 , pp. 963-966
    • Shimizu, H.1    Ross, R.K.2    Bernstein, L.3
  • 3
    • 0035229224 scopus 로고    scopus 로고
    • Chemoprevention in prostate cancer
    • Bergan RC, editor. Boston: Kluwer
    • Nabhan C, Bergan RC. Chemoprevention in prostate cancer. In: Bergan RC, editor. Cancer chemoprevention. Boston: Kluwer; 2001. p. 103-36.
    • (2001) Cancer Chemoprevention , pp. 103-136
    • Nabhan, C.1    Bergan, R.C.2
  • 4
    • 0030324994 scopus 로고    scopus 로고
    • Clinical development plan: Genistein
    • Clinical development plan: genistein. J Cell Biochem Suppl 1996;26:114-26.
    • (1996) J Cell Biochem Suppl , vol.26 , pp. 114-126
  • 5
    • 10744226314 scopus 로고    scopus 로고
    • Phase 1 pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer
    • Takimoto CH, Glover K, Huang X, et al. Phase 1 pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer. Cancer Epidemiol Biomarkers Prev 2003;12:1213-21.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 1213-1221
    • Takimoto, C.H.1    Glover, K.2    Huang, X.3
  • 6
    • 3843151539 scopus 로고    scopus 로고
    • Clinical characteristics and pharmacokinetics of purified soy isoflavones: Multiple-dose administration to men with prostate neoplasia
    • Fischer L, Mahoney C, Jeffcoat AR, et al. Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia. Nutr Cancer 2004;48:160-70.
    • (2004) Nutr Cancer , vol.48 , pp. 160-170
    • Fischer, L.1    Mahoney, C.2    Jeffcoat, A.R.3
  • 7
    • 0036135553 scopus 로고    scopus 로고
    • Clinical characteristics and pharmacokinetics of purified soy isoflavones: Single-dose administration to healthy men
    • Busby MG, Jeffcoat AR, Bloedon LT, et al. Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. Am J Clin Nutr 2002;75:126-36.
    • (2002) Am J Clin Nutr , vol.75 , pp. 126-136
    • Busby, M.G.1    Jeffcoat, A.R.2    Bloedon, L.T.3
  • 8
    • 0036830231 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of purified soy isoflavones: Single-dose administration to postmenopausal women
    • Bloedon LT, Jeffcoat AR, Lopaczynski W, et al. Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. Am J Clin Nutr 2002;76:1126-37.
    • (2002) Am J Clin Nutr , vol.76 , pp. 1126-1137
    • Bloedon, L.T.1    Jeffcoat, A.R.2    Lopaczynski, W.3
  • 9
    • 0035226930 scopus 로고    scopus 로고
    • Agent identification and preclinical testing
    • Bergan RC, editor. Boston: Kluwer
    • Crowell JA, Holmes CJ. Agent identification and preclinical testing. In: Bergan RC, editor. Cancer chemoprevention. Boston: Kluwer; 2001. p. 1-30.
    • (2001) Cancer Chemoprevention , pp. 1-30
    • Crowell, J.A.1    Holmes, C.J.2
  • 10
    • 0028898172 scopus 로고
    • High-performance liquid chromatographic assay for genistein in biological fluids
    • Supko JG, Phillips LR. High-performance liquid chromatographic assay for genistein in biological fluids. J Chromatogr B Biomed Appl 1995;666:157-67.
    • (1995) J Chromatogr B Biomed Appl , vol.666 , pp. 157-167
    • Supko, J.G.1    Phillips, L.R.2
  • 11
    • 0027383287 scopus 로고
    • Plasma concentrations of phyto-oestrogens in Japanese men
    • Adlercreutz H, Markkanen H, Watanabe S. Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 1993;342:1209-10.
    • (1993) Lancet , vol.342 , pp. 1209-1210
    • Adlercreutz, H.1    Markkanen, H.2    Watanabe, S.3
  • 12
    • 0032846010 scopus 로고    scopus 로고
    • Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants
    • Cook LS, Goldoft M, Schwartz SM, Weiss NS. Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants. J Urol 1999;161:152-5.
    • (1999) J Urol , vol.161 , pp. 152-155
    • Cook, L.S.1    Goldoft, M.2    Schwartz, S.M.3    Weiss, N.S.4
  • 13
    • 0029961485 scopus 로고    scopus 로고
    • Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to β-1-integrin
    • Bergan R, Kyle E, Nguyen P, et al. Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to β-1-integrin. Clin Exp Metastasis 1996;14:389-98.
    • (1996) Clin Exp Metastasis , vol.14 , pp. 389-398
    • Bergan, R.1    Kyle, E.2    Nguyen, P.3
  • 14
    • 0031017360 scopus 로고    scopus 로고
    • Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity
    • Kyle E, Neckers L, Takimoto C, Curt G, Bergan R. Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity. Mol Pharmacol 1997;51:193-200.
    • (1997) Mol Pharmacol , vol.51 , pp. 193-200
    • Kyle, E.1    Neckers, L.2    Takimoto, C.3    Curt, G.4    Bergan, R.5
  • 15
    • 0035062953 scopus 로고    scopus 로고
    • Focal adhesion kinase (FAK) phosphorylation is not required for genistein-induced FAK-b-1-integrin complex formation
    • Liu YU, Kyle E, Lieberman R, et al. Focal adhesion kinase (FAK) phosphorylation is not required for genistein-induced FAK-b-1-integrin complex formation. Clin Exp Metastasis 2000;18:203-12.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 203-212
    • Liu, Y.U.1    Kyle, E.2    Lieberman, R.3
  • 16
    • 0027245106 scopus 로고
    • Characterization of integrin subunits, cellular adhesion and tumorigenicity of four human prostate cell lines
    • Witkowski CM, Rabinovitz I, Nagle RB, Afflnito KS, Cress AE. Characterization of integrin subunits, cellular adhesion and tumorigenicity of four human prostate cell lines. J Cancer Res Clin Oncol 1993;119:637-44.
    • (1993) J Cancer Res Clin Oncol , vol.119 , pp. 637-644
    • Witkowski, C.M.1    Rabinovitz, I.2    Nagle, R.B.3    Afflnito, K.S.4    Cress, A.E.5
  • 17
    • 0034947013 scopus 로고    scopus 로고
    • Prostate cancer chemoprevention agents exhibit selective activity against early stage prostate cancer cells
    • Liu YQ, Kyle E, Patel S, et al. Prostate cancer chemoprevention agents exhibit selective activity against early stage prostate cancer cells. Prostate Cancer Prostatic Dis 2001;4:81-91.
    • (2001) Prostate Cancer Prostatic Dis , vol.4 , pp. 81-91
    • Liu, Y.Q.1    Kyle, E.2    Patel, S.3
  • 18
    • 0034186196 scopus 로고    scopus 로고
    • Genistein attenuates peritoneal metastasis of azoxymethane-induced intestinal adenocarcinomas in Wistar rats
    • Iishi H, Tatsuta M, Baba M, et al. Genistein attenuates peritoneal metastasis of azoxymethane-induced intestinal adenocarcinomas in Wistar rats. Int J Cancer 2000;86:416-20.
    • (2000) Int J Cancer , vol.86 , pp. 416-420
    • Iishi, H.1    Tatsuta, M.2    Baba, M.3
  • 19
    • 0344835900 scopus 로고    scopus 로고
    • Suppression of adhesion-induced protein tyrosine phosphorylation decreases invasive and metastatic potentials of B16-BL6 melanoma cells by protein tyrosine kinase inhibitor genistein
    • Yan C, Han R. Suppression of adhesion-induced protein tyrosine phosphorylation decreases invasive and metastatic potentials of B16-BL6 melanoma cells by protein tyrosine kinase inhibitor genistein. Invasion Metastasis 1997;17:189-98.
    • (1997) Invasion Metastasis , vol.17 , pp. 189-198
    • Yan, C.1    Han, R.2
  • 20
    • 0032479518 scopus 로고    scopus 로고
    • Genistein suppresses adhesion-induced protein tyrosine phosphorylation and invasion of B16-BL6 melanoma cells
    • Yan C, Han R. Genistein suppresses adhesion-induced protein tyrosine phosphorylation and invasion of B16-BL6 melanoma cells. Cancer Lett 1998;129:117-24.
    • (1998) Cancer Lett , vol.129 , pp. 117-124
    • Yan, C.1    Han, R.2
  • 21
    • 0031855920 scopus 로고    scopus 로고
    • Genistein inhibits both constitutive and EGF-stimulated invasion in ER-negative human breast carcinoma cell lines
    • Shao ZM, Wu J, Shen ZZ, Barsky SH. Genistein inhibits both constitutive and EGF-stimulated invasion in ER-negative human breast carcinoma cell lines. Anticancer Res 1998;18:1435-9.
    • (1998) Anticancer Res , vol.18 , pp. 1435-1439
    • Shao, Z.M.1    Wu, J.2    Shen, Z.Z.3    Barsky, S.H.4
  • 22
    • 0031016446 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain
    • Penar PL, Khoshyomn S, Bhushan A, Tritton TR. Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain. Neurosurgery 1997;40:141-51.
    • (1997) Neurosurgery , vol.40 , pp. 141-151
    • Penar, P.L.1    Khoshyomn, S.2    Bhushan, A.3    Tritton, T.R.4
  • 23
    • 18744362140 scopus 로고    scopus 로고
    • Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion
    • Liu Y, Jovanovic B, Pins M, Lee C, Bergan RC. Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion. Oncogene 2002;21:8272-81.
    • (2002) Oncogene , vol.21 , pp. 8272-8281
    • Liu, Y.1    Jovanovic, B.2    Pins, M.3    Lee, C.4    Bergan, R.C.5
  • 24
    • 0032932903 scopus 로고    scopus 로고
    • Transforming growth factor-β 1 increases the adhesion of MDA-MB-231 mammary adenocarcinoma cells to the microvascular subendothelium
    • Loganadane LD, Vassy J, Legrand C, Fauvel-Lafeve F. Transforming growth factor-β 1 increases the adhesion of MDA-MB-231 mammary adenocarcinoma cells to the microvascular subendothelium. Cell Adhes Commun 1999;7:57-71.
    • (1999) Cell Adhes Commun , vol.7 , pp. 57-71
    • Loganadane, L.D.1    Vassy, J.2    Legrand, C.3    Fauvel-Lafeve, F.4
  • 25
    • 0032915758 scopus 로고    scopus 로고
    • Osteoblast conditioned media contain TGF-β1 and modulate the migration of prostate tumor cells and their interactions with extracellular matrix components
    • Festuccia C, Bologna M, Gravina GL, et al. Osteoblast conditioned media contain TGF-β1 and modulate the migration of prostate tumor cells and their interactions with extracellular matrix components. Int J Cancer 1999;81:395-403.
    • (1999) Int J Cancer , vol.81 , pp. 395-403
    • Festuccia, C.1    Bologna, M.2    Gravina, G.L.3
  • 26
    • 0031050528 scopus 로고    scopus 로고
    • Transforming growth factor β upregulates the integrin-mediated adhesion of human prostatic carcinoma cells to type I collagen
    • Kostenuik PJ, Singh G, Orr FW. Transforming growth factor β upregulates the integrin-mediated adhesion of human prostatic carcinoma cells to type I collagen. Clin Exp Metastasis 1997;15:41-52.
    • (1997) Clin Exp Metastasis , vol.15 , pp. 41-52
    • Kostenuik, P.J.1    Singh, G.2    Orr, F.W.3
  • 27
    • 0043068003 scopus 로고    scopus 로고
    • p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion
    • Haves SA, Huang X, Kambhampati S, Platanias LC, Bergan RC. p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion. Oncogene 2003;22:4841-50.
    • (2003) Oncogene , vol.22 , pp. 4841-4850
    • Haves, S.A.1    Huang, X.2    Kambhampati, S.3    Platanias, L.C.4    Bergan, R.C.5
  • 28
    • 0035000670 scopus 로고    scopus 로고
    • Proteases in invasion: Matrix metalloproteinases
    • Stetler-Stevenson WG, Yu AE. Proteases in invasion: matrix metalloproteinases. Semin Cancer Biol 2001;11:143-52.
    • (2001) Semin Cancer Biol , vol.11 , pp. 143-152
    • Stetler-Stevenson, W.G.1    Yu, A.E.2
  • 29
    • 0033376888 scopus 로고    scopus 로고
    • Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: Change in cellular localization associated with high-grade prostatic intraepithelial neoplasia
    • Upadhyay J, Shekarriz B, Nemeth JA, et al. Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia. Clin Cancer Res 1999;5:4105-10.
    • (1999) Clin Cancer Res , vol.5 , pp. 4105-4110
    • Upadhyay, J.1    Shekarriz, B.2    Nemeth, J.A.3
  • 30
    • 0030910423 scopus 로고    scopus 로고
    • In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer
    • Wood M, Fudge K, Mohler JL, et al. In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer. Clin Exp Metastasis 1997;15:246-58.
    • (1997) Clin Exp Metastasis , vol.15 , pp. 246-258
    • Wood, M.1    Fudge, K.2    Mohler, J.L.3
  • 31
    • 0029923193 scopus 로고    scopus 로고
    • Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase
    • McLaughlin MM, Kumar S, McDonnell PC, et al. Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase. J Biol Chem 1996;271:8488-92.
    • (1996) J Biol Chem , vol.271 , pp. 8488-8492
    • McLaughlin, M.M.1    Kumar, S.2    McDonnell, P.C.3
  • 32
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard B, Raingeaud J, Barrett T, et al. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 1995;267:682-5.
    • (1995) Science , vol.267 , pp. 682-685
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3
  • 33
    • 0031928243 scopus 로고    scopus 로고
    • Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21waf1/cip1
    • Rohlff C, Blagosklonny MV, Kyle E, et al. Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21waf1/cip1. Prostate 1998;37:51-9.
    • (1998) Prostate , vol.37 , pp. 51-59
    • Rohlff, C.1    Blagosklonny, M.V.2    Kyle, E.3
  • 34
    • 0030048263 scopus 로고    scopus 로고
    • Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β 1 in human prostate cancer cells
    • Kim IY, Ahn HJ, Zelner DJ, et al. Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β 1 in human prostate cancer cells. Cancer Res 1996;56:44-8.
    • (1996) Cancer Res , vol.56 , pp. 44-48
    • Kim, I.Y.1    Ahn, H.J.2    Zelner, D.J.3
  • 35
    • 0031776562 scopus 로고
    • Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients
    • Kim IY, Ahn HJ, Lang S, et al. Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients. Clin Cancer Res 1993;4:1625-30.
    • (1993) Clin Cancer Res , vol.4 , pp. 1625-1630
    • Kim, I.Y.1    Ahn, H.J.2    Lang, S.3
  • 36
    • 9544242713 scopus 로고    scopus 로고
    • Loss of expression of transforming growth factor β type I and type II receptors correlates with tumor grade in human prostate cancer tissues
    • Kim IY, Ahn HJ, Zelner DJ, et al. Loss of expression of transforming growth factor β type I and type II receptors correlates with tumor grade in human prostate cancer tissues. Clin Cancer Res 1996;2:1255-61.
    • (1996) Clin Cancer Res , vol.2 , pp. 1255-1261
    • Kim, I.Y.1    Ahn, H.J.2    Zelner, D.J.3
  • 37
    • 0030002175 scopus 로고    scopus 로고
    • Transforming growth factor β1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro
    • Sehgal I, Baley PA, Thompson TC. Transforming growth factor β1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro. Cancer Res 1996;56:3359-65.
    • (1996) Cancer Res , vol.56 , pp. 3359-3365
    • Sehgal, I.1    Baley, P.A.2    Thompson, T.C.3
  • 38
    • 0032918016 scopus 로고    scopus 로고
    • Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-β1 in human prostate cancer cell lines
    • Sehgal I, Thompson TC. Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-β1 in human prostate cancer cell lines. Mol Biol Cell 1999;10:407-16.
    • (1999) Mol Biol Cell , vol.10 , pp. 407-416
    • Sehgal, I.1    Thompson, T.C.2
  • 39
    • 0038792224 scopus 로고    scopus 로고
    • Map kinase signaling pathways and hematologic malignancies
    • Platanias LC. Map kinase signaling pathways and hematologic malignancies. Blood 2003;101:4667-79.
    • (2003) Blood , vol.101 , pp. 4667-4679
    • Platanias, L.C.1
  • 40
    • 0030954172 scopus 로고    scopus 로고
    • A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket
    • Tong L, Pav S, White DM, et al. A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket. Nat Struct Biol 1997;4:311-6.
    • (1997) Nat Struct Biol , vol.4 , pp. 311-316
    • Tong, L.1    Pav, S.2    White, D.M.3
  • 41
    • 12644277392 scopus 로고    scopus 로고
    • The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase
    • Wilson KP, McCaffrey PG, Hsiao K, et al. The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase. Chem Biol 1997;4:423-31.
    • (1997) Chem Biol , vol.4 , pp. 423-431
    • Wilson, K.P.1    McCaffrey, P.G.2    Hsiao, K.3
  • 42
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, ten Dijke P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 1997;390:465-71.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 43
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signaling: Receptors, transducers, and Mad proteins
    • Massague J. TGFβ signaling: receptors, transducers, and Mad proteins. Cell 1996;85:947-50.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massague, J.1
  • 44
    • 0028937160 scopus 로고
    • Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor β receptor kinases
    • Chen F, Weinberg RA. Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor β receptor kinases. Proc Natl Acad Sci U S A 1995;92:1565-9.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1565-1569
    • Chen, F.1    Weinberg, R.A.2
  • 45
    • 0035227495 scopus 로고    scopus 로고
    • Basic pharmacokinetics and pharmacodynamic principals
    • Bergan RC, editor. Boston: Kluwer
    • Takimoto CH. Basic pharmacokinetics and pharmacodynamic principals. In: Bergan RC, editor. Cancer Chemoprevention. Boston: Kluwer; 2001. p. 85-102.
    • (2001) Cancer Chemoprevention , pp. 85-102
    • Takimoto, C.H.1
  • 46
    • 0025181114 scopus 로고
    • Western diet and western diseases: Some hormonal and biochemical mechanisms and associations
    • Adlercreutz H. Western diet and western diseases: some hormonal and biochemical mechanisms and associations. Scand J Clin Lab Invest 1990;50 Suppl 201:3-23.
    • (1990) Scand J Clin Lab Invest , vol.50 , Issue.201 SUPPL. , pp. 3-23
    • Adlercreutz, H.1
  • 47
    • 2642682426 scopus 로고    scopus 로고
    • In situ hybridization analysis of genes coding collagen IV α1 chain, laminin β1 chain, and S-laminin in prostate tissue and prostate cancer: Increased basement membrane gene expression in high-grade and metastatic lesions
    • Pfohler C, Fixemer T, Jung V, et al. In situ hybridization analysis of genes coding collagen IV α1 chain, laminin β1 chain, and S-laminin in prostate tissue and prostate cancer: increased basement membrane gene expression in high-grade and metastatic lesions. Prostate 1998;36:143-50.
    • (1998) Prostate , vol.36 , pp. 143-150
    • Pfohler, C.1    Fixemer, T.2    Jung, V.3
  • 48
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994;372:739-46.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 49
    • 0023664272 scopus 로고
    • Genistein, a specific inhibitor of tyrosine-specific protein kinases
    • Akiyama T, Ishida J, Nakagawa S, et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 1987;262:5592-5.
    • (1987) J Biol Chem , vol.262 , pp. 5592-5595
    • Akiyama, T.1    Ishida, J.2    Nakagawa, S.3
  • 50
    • 0036716282 scopus 로고    scopus 로고
    • Strategies for MMP inhibition in cancer: Innovations for the post-trial era
    • Overall CM, Lopez-Otin C. Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat Rev Cancer 2002;2:657-72.
    • (2002) Nat Rev Cancer , vol.2 , pp. 657-672
    • Overall, C.M.1    Lopez-Otin, C.2


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