Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids

Obstetrics and Gynecology

Volumn 103, Issue 5 I, 2004, Pages 892-898

  Maubach, Julie ^b   Depypere, Herman T ^b   Goeman, Jan ^b   Van Der Eycken, Johan ^b   Heyerick, Arne ^b   Bracke, Marc E ^b   Blondeel, Philippe ^b   De Keukeleire, Denis ^a  

^a GHENT UNIVERSITY   (Belgium)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DAIDZEIN; EQUOL; ESTROGEN; ESTROGEN RECEPTOR; GENISTEIN; PHYTOESTROGEN; PLACEBO; ISOFLAVONE DERIVATIVE; PLANT MEDICINAL PRODUCT;

ADIPOSE TISSUE; ADULT; ARTICLE; BODY FLUID; BREAST; BREAST SURGERY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG URINE LEVEL; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PHYTOCHEMISTRY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SOYBEAN; STATISTICAL SIGNIFICANCE; TISSUE DISTRIBUTION; TISSUE HOMOGENATE; COMPARATIVE STUDY; METABOLISM; MIDDLE AGED;

ADULT; BODY FLUIDS; BREAST; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; GENISTEIN; HUMANS; ISOFLAVONES; MIDDLE AGED; PHYTOESTROGENS; PLANT PREPARATIONS; SOY FOODS; TISSUE DISTRIBUTION;

EID: 2942752003     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.AOG.0000124983.66521.6a     Document Type: Article

References (20)

1. Cassidy A, Faughnan M. Phytoestrogens through the life cycle. Proc Nutr Soc 2000;59:489-96.
2. Wuttke W, Jarry H, Westphalen S, Christoffel V, Seitlova-Wuttke D. Phytoestrogens for hormone replacement therapy? J Steroid Biochem Mol Biol 2002;83:133-47.
3. Ren M, Kuhn G, Wegner J, Chen J. Isoflavones, substances with multi-biological and clinical properties. Eur J Nutr 2001;40:135-46.
4. Haddad N, Fuqua J. Phytoestrogens: effects on the reproductive system. Endocrinologist 2001;11:498-505.
5. Franke AA, Custer LJ, Tanaka Y. Isoflavones in human breast milk and other biological fluids. Am J Clin Nutr 1998;68 suppl:1466S-73S.
6. Morton MS, Chan PS, Cheng C, Blacklock N, Matos-Ferreira A, Abranches-Monteiro L, et al. Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom. Prostate 1997;32:122-8.
7. Maubach J, Bracke ME, Heyerick A, Depypere HT, Serreyn RF, Mareel MM, et al. Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2003;784: 137-44.
8. Evers JM, Wightman LM, Crawford RA, Contarini G, Coors U, Farrington DS, et al. A precise method to measure the total fat content of spreadable fats. Int Dairy J 2000;10:815-27.
9. Lampe JW. Isoflavonoid and lignan phytoestrogens as dietary biomarkers. J Nutr 2003;133 suppl:956S-64S.
10. Hargreaves DF, Potten CS, Harding C, Shaw LE, Morton MS, Roberts SA, et al. Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast. J Clin Endocrinol Metab 1999;84:4017-24.
11. Setchell KD, Zimmer-Nechemias L, Cai J, Heubi JE. Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life. Am J Clin Nutr 1998; 68(suppl):1453S-61S.
12. Setchell K, Faughnan M, Avades T, Zimmer-Neschemias L, Brown N, Wolfe B, et al. Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women. Am J Clin Nutr 2003; 77:411-9.
13. Setchell KD, Brown NM, Zimmer-Nechemias L, Brashear WT, Wolfe BE, Kirschner AS, et al. Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability. Am J Clin Nutr 2002;76:447-53.
14. Xu X, Harris KS, Wang HJ, Murphy PA, Hendrich S. Bioavailability of soybean isoflavones depends upon gut microflora in women. J Nutr 1995;125:2307-15.
15. Setchell KD, Brown NM, Desai P, Zimmer-Nechemias L, Wolfe BE, Brashear WT, et al. Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements. J Nutr 2001;131 suppl: 1362S-75S.
16. Busby MG, Jeffcoat A, Bloedon LT, Koch MA, Black T, Dix KJ, et al. Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. Am J Clin Nutr 2002;75:126-36.
17. Morton M, Arisaka O, Miyake N, Morgan L, Evans B. Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. J Nutr 2002;132: 3168-71.
18. Pumford S, Morton M, Turkes A, Griffiths K. Determination of the isoflavonoids genistein and daidzein in biological samples by gas chromatography-mass spectrometry. Ann Clin Biochem 2002;39:281-92.
19. Lampe JW, Gustafsson DR, Hutchins AM, Martini MC, Li S, Wähälä K, et al. Urinary isoflavonoid and lignan excretion on a Western diet: relation to soy, vegetable, and fruit intake. Cancer Epidemiol Biomarkers Prev 1999;8: 699-707.
20. Adlercreutz H, Fotsis T, Lampe J, Wähälä K, Makela T, Brunow G, et al. Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry. Scand J Clin Lab Invest Suppl 1993;215:5-18.