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Volumn 90, Issue 2, 2003, Pages 457-465

A potential protective mechanism of soya isoflavones against 7,12-dimethylbenz[a]anthracene tumour initiation

Author keywords

Dimethylbenz(a)anthracene lesions; Genistein; Isoflavones; Phase I cytochrome P450 enzymes

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DAIDZEIN; DNA; GENISTEIN; ISOFLAVONE DERIVATIVE; MESSENGER RNA;

EID: 0041561001     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN2003913     Document Type: Article
Times cited : (54)

References (56)
  • 1
    • 0032881196 scopus 로고    scopus 로고
    • Soy induces phase II enzymes but does not inhibit dimethylbenz[a]anthracene-induced carcinogenesis in female rats
    • Appelt LC & Reicks MM (1999) Soy induces phase II enzymes but does not inhibit dimethylbenz[a]anthracene-induced carcinogenesis in female rats. J Nutr 129, 1820-1826.
    • (1999) J Nutr , vol.129 , pp. 1820-1826
    • Appelt, L.C.1    Reicks, M.M.2
  • 2
    • 0031438078 scopus 로고    scopus 로고
    • Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells
    • Backlund M, Johansson I, Mkrtchian S & Ingelman-Sundberg M (1997) Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells. J Biol Chem 272, 31755-31763.
    • (1997) J Biol Chem , vol.272 , pp. 31755-31763
    • Backlund, M.1    Johansson, I.2    Mkrtchian, S.3    Ingelman-Sundberg, M.4
  • 3
    • 0031831117 scopus 로고    scopus 로고
    • Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF-7 cell proliferation assay
    • Breinholt V & Larsen JC (1998) Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF-7 cell proliferation assay. Chem Res Toxicol 11, 622-629.
    • (1998) Chem Res Toxicol , vol.11 , pp. 622-629
    • Breinholt, V.1    Larsen, J.C.2
  • 4
    • 0033514998 scopus 로고    scopus 로고
    • Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas
    • Buters JT, Sakai S, Richter T, et al. (1999) Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas. Proc Natl Acad Sci USA 96, 1977-1982.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1977-1982
    • Buters, J.T.1    Sakai, S.2    Richter, T.3
  • 5
    • 0026522952 scopus 로고
    • Effects of synthetic and naturally occurring flavonoids on metabolic activation of benzo[a]pyrene in hamster embryo cell cultures
    • Chae YH, Ho DK, Cassady JM, Cook VM, Marcus CB & Baird WM (1992) Effects of synthetic and naturally occurring flavonoids on metabolic activation of benzo[a]pyrene in hamster embryo cell cultures. Chem Biol Interact 82, 181-193.
    • (1992) Chem Biol Interact , vol.82 , pp. 181-193
    • Chae, Y.H.1    Ho, D.K.2    Cassady, J.M.3    Cook, V.M.4    Marcus, C.B.5    Baird, W.M.6
  • 6
    • 0033916580 scopus 로고    scopus 로고
    • Mass spectrometric determination of genistein tissue distribution in diet-exposed Sprague-Dawley rats
    • Chang HC, Churchwell MI, Delclos KB, Newbold RR & Doerge DR (2000) Mass spectrometric determination of genistein tissue distribution in diet-exposed Sprague-Dawley rats. J Nutr 130, 1963-1970.
    • (2000) J Nutr , vol.130 , pp. 1963-1970
    • Chang, H.C.1    Churchwell, M.I.2    Delclos, K.B.3    Newbold, R.R.4    Doerge, D.R.5
  • 7
    • 0032862195 scopus 로고    scopus 로고
    • Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol
    • Ciolino HP & Yeh GC (1999) Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. Mol Pharmacol 56, 760-767.
    • (1999) Mol Pharmacol , vol.56 , pp. 760-767
    • Ciolino, H.P.1    Yeh, G.C.2
  • 8
    • 0034075877 scopus 로고    scopus 로고
    • Effect of intact and isoflavone-depleted soy protein on NMU-induced rat mammary tumorigenesis
    • Cohen LA, Zhao Z, Pittman B & Scimeca JA (2000) Effect of intact and isoflavone-depleted soy protein on NMU-induced rat mammary tumorigenesis. Carcinogenesis 21, 929-935.
    • (2000) Carcinogenesis , vol.21 , pp. 929-935
    • Cohen, L.A.1    Zhao, Z.2    Pittman, B.3    Scimeca, J.A.4
  • 9
    • 0035527479 scopus 로고    scopus 로고
    • Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats
    • Constantinou AI, Lantvit D, Hawthorne M, Xu X, Van Breemen RB & Pezzuto JM (2001) Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats. Nutr Cancer 41, 75-81.
    • (2001) Nutr Cancer , vol.41 , pp. 75-81
    • Constantinou, A.I.1    Lantvit, D.2    Hawthorne, M.3    Xu, X.4    Van Breemen, R.B.5    Pezzuto, J.M.6
  • 10
  • 11
    • 0034662379 scopus 로고    scopus 로고
    • Effect of 3′-methoxy-4′-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent and -independent mechanisms
    • Dertinger SD, Lantum HB, Silverstone AE & Gasiewicz TA (2000) Effect of 3′-methoxy-4′-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent and -independent mechanisms. Biochem Pharmacol 60, 189-196.
    • (2000) Biochem Pharmacol , vol.60 , pp. 189-196
    • Dertinger, S.D.1    Lantum, H.B.2    Silverstone, A.E.3    Gasiewicz, T.A.4
  • 12
    • 0028978209 scopus 로고
    • Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) - Sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells
    • Dohr O, Vogel C & Abel J (1995) Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) - Sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells. Arch Biochem Biophys 321, 405-412.
    • (1995) Arch Biochem Biophys , vol.321 , pp. 405-412
    • Dohr, O.1    Vogel, C.2    Abel, J.3
  • 14
    • 0032437643 scopus 로고    scopus 로고
    • Dietary genistein: Perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat
    • Fritz WA, Coward L, Wang J & Lamartiniere CA (1998) Dietary genistein: Perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat. Carcinogenesis 19, 2151-2158.
    • (1998) Carcinogenesis , vol.19 , pp. 2151-2158
    • Fritz, W.A.1    Coward, L.2    Wang, J.3    Lamartiniere, C.A.4
  • 15
    • 0035175406 scopus 로고    scopus 로고
    • Chemoprevention of DMBA-induced mammary cancer in rats by dietary soy
    • Gallo D, Giacomelli S, Cantelmo F, et al. (2001) Chemoprevention of DMBA-induced mammary cancer in rats by dietary soy. Breast Cancer Res Treat 69, 153-164.
    • (2001) Breast Cancer Res Treat , vol.69 , pp. 153-164
    • Gallo, D.1    Giacomelli, S.2    Cantelmo, F.3
  • 16
    • 0029120973 scopus 로고
    • Genetic damage and the inhibition of 7,12-dimethyl-benz[a]anthracene-induced genetic damage by the phytoestrogens, genistein and daidzein, in female ICR mice
    • Giri AK & Lu LJ (1995) Genetic damage and the inhibition of 7,12-dimethyl-benz[a]anthracene-induced genetic damage by the phytoestrogens, genistein and daidzein, in female ICR mice. Cancer Lett 95, 125-133.
    • (1995) Cancer Lett , vol.95 , pp. 125-133
    • Giri, A.K.1    Lu, L.J.2
  • 17
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
    • Gonzalez FJ & Gelboin HV (1994) Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab Rev 26, 165-183.
    • (1994) Drug Metab Rev , vol.26 , pp. 165-183
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 18
    • 0033959892 scopus 로고    scopus 로고
    • Diets containing whey proteins or soy protein isolate protect against 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female rats
    • Hakkak R, Korourian S, Shelnutt SR, Lensing S, Ronis MJ & Badger TM (2000) Diets containing whey proteins or soy protein isolate protect against 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female rats. Cancer Epidemiol Biomarkers Prev 9, 113-117.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 113-117
    • Hakkak, R.1    Korourian, S.2    Shelnutt, S.R.3    Lensing, S.4    Ronis, M.J.5    Badger, T.M.6
  • 19
    • 0031835035 scopus 로고    scopus 로고
    • Inhibition of mouse and human CYP1A- and 2E1dependent substrate metabolism by the isoflavonoids genistein and equol
    • Helsby NA, Chipman JK, Gescher A & Kerr D (1998) Inhibition of mouse and human CYP1A- and 2E1dependent substrate metabolism by the isoflavonoids genistein and equol. Food Chem Toxicol 36, 375-382.
    • (1998) Food Chem Toxicol , vol.36 , pp. 375-382
    • Helsby, N.A.1    Chipman, J.K.2    Gescher, A.3    Kerr, D.4
  • 20
    • 0032774109 scopus 로고    scopus 로고
    • Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis
    • Hilakivi-Clarke L, Onojafe I, Raygada M, et al. (1999) Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis. Br J Cancer 80, 1682-1688.
    • (1999) Br J Cancer , vol.80 , pp. 1682-1688
    • Hilakivi-Clarke, L.1    Onojafe, I.2    Raygada, M.3
  • 21
    • 0036685480 scopus 로고    scopus 로고
    • Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol
    • Horn TL, Reichert MA, Bliss RL & Malejka-Giganti D (2002) Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol. Biochem Pharmacol 64, 393-404.
    • (2002) Biochem Pharmacol , vol.64 , pp. 393-404
    • Horn, T.L.1    Reichert, M.A.2    Bliss, R.L.3    Malejka-Giganti, D.4
  • 22
    • 0021007163 scopus 로고
    • Polynuclear aromatic compounds, part I, chemical, environmental and experimental data
    • International Agency for Research on Cancer (1983) Polynuclear aromatic compounds, part I, chemical, environmental and experimental data. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Human, 32, 1-453.
    • (1983) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Human , vol.32 , pp. 1-453
  • 24
    • 0033949949 scopus 로고    scopus 로고
    • Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans
    • Izumi T, Piskula MK, Osawa S, et al. (2000) Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans. J Nutr 130, 1695-1699.
    • (2000) J Nutr , vol.130 , pp. 1695-1699
    • Izumi, T.1    Piskula, M.K.2    Osawa, S.3
  • 25
    • 0036790022 scopus 로고    scopus 로고
    • Soy isoflavones increase latency of spontaneous mammary tumour in mice
    • Jin Z & MacDonald RS (2002) Soy isoflavones increase latency of spontaneous mammary tumour in mice. J Nutr 132, 3186-3190.
    • (2002) J Nutr , vol.132 , pp. 3186-3190
    • Jin, Z.1    MacDonald, R.S.2
  • 26
    • 0035158466 scopus 로고    scopus 로고
    • Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors in implanted in athymic nude mice
    • Ju YH, Allred CD, Allred KF, Karko KL, Doerge DR & Helferich WG (2001) Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors in implanted in athymic nude mice. J Nutr 131, 2957-2962.
    • (2001) J Nutr , vol.131 , pp. 2957-2962
    • Ju, Y.H.1    Allred, C.D.2    Allred, K.F.3    Karko, K.L.4    Doerge, D.R.5    Helferich, W.G.6
  • 27
    • 0036168607 scopus 로고    scopus 로고
    • Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz-[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation
    • Kleiner HE, Vulimiri SV, Reed MJ, Uberecken A & DiGiovanni J (2002) Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz-[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation. Chem Res Toxicol 15, 226-235.
    • (2002) Chem Res Toxicol , vol.15 , pp. 226-235
    • Kleiner, H.E.1    Vulimiri, S.V.2    Reed, M.J.3    Uberecken, A.4    DiGiovanni, J.5
  • 28
    • 0034660372 scopus 로고    scopus 로고
    • An aryl hydrocarbon receptor conformation acts as the functional core of nuclear dioxin signaling
    • Kronenberg S, Esser C & Carlberg C (2000) An aryl hydrocarbon receptor conformation acts as the functional core of nuclear dioxin signaling. Nucleic Acids Res 28, 2286-2291.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2286-2291
    • Kronenberg, S.1    Esser, C.2    Carlberg, C.3
  • 32
    • 0032516686 scopus 로고    scopus 로고
    • Estrogenic and anti-proliferative activities on MCF-7 human breast cancer cells by flavonoids
    • Le Bail JC, Varnet F, Nicolas JC & Habrioux G (1998) Estrogenic and anti-proliferative activities on MCF-7 human breast cancer cells by flavonoids. Cancer Lett 130, 209-216.
    • (1998) Cancer Lett , vol.130 , pp. 209-216
    • Le Bail, J.C.1    Varnet, F.2    Nicolas, J.C.3    Habrioux, G.4
  • 33
    • 0028313983 scopus 로고
    • The structure-activity relationships of flavonoids as inhibitors of cytochrome p-450 enzymes in rat liver microsomes and the mutagenicity of 2-amino-3-methyl-imidazo[4,5-f]quinolone
    • Lee H, Wang HW, Su HY & Hao NJ (1994) The structure-activity relationships of flavonoids as inhibitors of cytochrome p-450 enzymes in rat liver microsomes and the mutagenicity of 2-amino-3-methyl-imidazo[4,5-f]quinolone. Mutagenesis 9, 101-106.
    • (1994) Mutagenesis , vol.9 , pp. 101-106
    • Lee, H.1    Wang, H.W.2    Su, H.Y.3    Hao, N.J.4
  • 34
    • 0034533197 scopus 로고    scopus 로고
    • Bcl-2 is not reduced in the death of MCF-7 cells at low genistein concentration
    • Leung LK & Wang TT (2000) Bcl-2 is not reduced in the death of MCF-7 cells at low genistein concentration. J Nutr 130, 2922-2926.
    • (2000) J Nutr , vol.130 , pp. 2922-2926
    • Leung, L.K.1    Wang, T.T.2
  • 35
    • 0030024024 scopus 로고    scopus 로고
    • Aromatic DNA adducts in adjacent tissues of breast cancer patients: Clues to breast cancer etiology
    • Li D, Wang M, Dhingra K & Hittelman WN (1996) Aromatic DNA adducts in adjacent tissues of breast cancer patients: Clues to breast cancer etiology. Cancer Res 56, 287-293.
    • (1996) Cancer Res , vol.56 , pp. 287-293
    • Li, D.1    Wang, M.2    Dhingra, K.3    Hittelman, W.N.4
  • 36
    • 0035872470 scopus 로고    scopus 로고
    • Dibenzoylmethane modulates aryl hydrocarbon receptor function and expression of cytochromes P50 1A1, 1A2, and 1B1
    • MacDonald CJ, Ciolino HP & Yeh GC (2001) Dibenzoylmethane modulates aryl hydrocarbon receptor function and expression of cytochromes P50 1A1, 1A2, and 1B1. Cancer Res 61, 3919-3924.
    • (2001) Cancer Res , vol.61 , pp. 3919-3924
    • MacDonald, C.J.1    Ciolino, H.P.2    Yeh, G.C.3
  • 37
    • 0036790042 scopus 로고    scopus 로고
    • Phytoestrogen concentrations in serum from Japanese men and women over forty years of age
    • Morton MS, Arisaka O, Miyake N, Morgan LD & Evans BAJ (2002) Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. J Nutr 132, 3168-3171.
    • (2002) J Nutr , vol.132 , pp. 3168-3171
    • Morton, M.S.1    Arisaka, O.2    Miyake, N.3    Morgan, L.D.4    Evans, B.A.J.5
  • 38
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 39
    • 0026044563 scopus 로고
    • Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene
    • Peterson G & Barnes S (1991) Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene. Biochem Biophys Res Commun 179, 661-667.
    • (1991) Biochem Biophys Res Commun , vol.179 , pp. 661-667
    • Peterson, G.1    Barnes, S.2
  • 40
    • 0036850979 scopus 로고    scopus 로고
    • Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects
    • Po LS, Wang TT, Chen ZY & Leung LK (2002) Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects. Br J Nutr 88, 463-469.
    • (2002) Br J Nutr , vol.88 , pp. 463-469
    • Po, L.S.1    Wang, T.T.2    Chen, Z.Y.3    Leung, L.K.4
  • 41
    • 0035212383 scopus 로고    scopus 로고
    • Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats
    • Rowlands JC, He L, Hakkak R, Ronis MJJ & Badger TM (2001) Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats. J Nutr 131, 3281-3287.
    • (2001) J Nutr , vol.131 , pp. 3281-3287
    • Rowlands, J.C.1    He, L.2    Hakkak, R.3    Ronis, M.J.J.4    Badger, T.M.5
  • 42
    • 0035977882 scopus 로고    scopus 로고
    • Molecular biology of the Ah receptor and its role in carcinogenesis
    • Safe S (2001) Molecular biology of the Ah receptor and its role in carcinogenesis. Toxicol Lett 120, 1-7.
    • (2001) Toxicol Lett , vol.120 , pp. 1-7
    • Safe, S.1
  • 43
    • 0032054451 scopus 로고    scopus 로고
    • Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by p21WAF1/CIP1 induction G2/M arrest and apoptosis
    • Shao ZM, Alpaugh ML, Fontana JA, Barsky SH (1998) Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by p21WAF1/CIP1 induction G2/M arrest and apoptosis. J Cell Biochem 69, 44-54.
    • (1998) J Cell Biochem , vol.69 , pp. 44-54
    • Shao, Z.M.1    Alpaugh, M.L.2    Fontana, J.A.3    Barsky, S.H.4
  • 44
    • 0032727692 scopus 로고    scopus 로고
    • Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones
    • Shertzer HG, Puga A, Chang C, et al. (1999) Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones. Chem Biol Interact 123, 31-49.
    • (1999) Chem Biol Interact , vol.123 , pp. 31-49
    • Shertzer, H.G.1    Puga, A.2    Chang, C.3
  • 45
    • 0034681182 scopus 로고    scopus 로고
    • Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor
    • Shimizu Y, Nakatsuru Y, Ichinose M, et al. (2000) Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor. Proc Natl Acad Sci USA 97, 779-782.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 779-782
    • Shimizu, Y.1    Nakatsuru, Y.2    Ichinose, M.3
  • 46
    • 0035451810 scopus 로고    scopus 로고
    • Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a,1]pyrene in the human breast cells MCF-7
    • Smith WA, Freeman JW & Gupta RC (2001) Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a,1]pyrene in the human breast cells MCF-7. Mutat Res 480-481, 97-108.
    • (2001) Mutat Res , vol.480-481 , pp. 97-108
    • Smith, W.A.1    Freeman, J.W.2    Gupta, R.C.3
  • 47
    • 0031590969 scopus 로고    scopus 로고
    • Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen
    • So FV, Guthrie N, Chambers AF & Carroll KK (1997) Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen. Cancer Lett 112, 127-133.
    • (1997) Cancer Lett , vol.112 , pp. 127-133
    • So, F.V.1    Guthrie, N.2    Chambers, A.F.3    Carroll, K.K.4
  • 48
    • 0031926907 scopus 로고    scopus 로고
    • 12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells
    • Spink BC, Fasco MJ, Gierthy JF & Spink DC (1998a) 12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells. J Cell Biochem 70, 289-296.
    • (1998) J Cell Biochem , vol.70 , pp. 289-296
    • Spink, B.C.1    Fasco, M.J.2    Gierthy, J.F.3    Spink, D.C.4
  • 49
    • 0031927210 scopus 로고    scopus 로고
    • Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells
    • Spink DC, Spink BC, Cao JQ, et al. (1998b) Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. Carcinogenesis 19, 291-298.
    • (1998) Carcinogenesis , vol.19 , pp. 291-298
    • Spink, D.C.1    Spink, B.C.2    Cao, J.Q.3
  • 50
    • 0033372225 scopus 로고    scopus 로고
    • International collaborative study on genetic susceptibility to environmental carcinogens
    • Taioli E (1999) International collaborative study on genetic susceptibility to environmental carcinogens. Cancer Epidemiol Biomarkers Prev 8, 727-728.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 727-728
    • Taioli, E.1
  • 51
    • 0031695864 scopus 로고    scopus 로고
    • Effect of dietary soy protein isolate, genistein, and 1,4-phenylenebis(methylene)-selenocyanate on DNA binding of 7,12-dimethyl-benz[a]anthracene in mammary glands of CD rats
    • Upadhyaya P & El-Bayoumy K (1998) Effect of dietary soy protein isolate, genistein, and 1,4-phenylenebis(methylene)-selenocyanate on DNA binding of 7,12-dimethyl-benz[a]anthracene in mammary glands of CD rats. Oncol Rep 5, 1541-1545.
    • (1998) Oncol Rep , vol.5 , pp. 1541-1545
    • Upadhyaya, P.1    El-Bayoumy, K.2
  • 52
    • 0030880014 scopus 로고    scopus 로고
    • Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells
    • Wang C & Kurzer MS (1997) Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells. Nutr Cancer 28, 236-247.
    • (1997) Nutr Cancer , vol.28 , pp. 236-247
    • Wang, C.1    Kurzer, M.S.2
  • 53
    • 0029007175 scopus 로고
    • Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7
    • Wang TT & Phang JM (1995) Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res 55, 2487-2489.
    • (1995) Cancer Res , vol.55 , pp. 2487-2489
    • Wang, T.T.1    Phang, J.M.2
  • 54
    • 0037315155 scopus 로고    scopus 로고
    • Glucuronides are the main isoflavone metabolites in women
    • Zhang Y, Hendrich S & Murphy PA (2003) Glucuronides are the main isoflavone metabolites in women. J Nutr 133, 399-404.
    • (2003) J Nutr , vol.133 , pp. 399-404
    • Zhang, Y.1    Hendrich, S.2    Murphy, P.A.3
  • 55
    • 0033998724 scopus 로고    scopus 로고
    • Genetic polymorphism of P450 1B1 and risk of breast cancer
    • Zheng W, Xie DW, Jin F, et al. (2000) Genetic polymorphism of P450 1B1 and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 9, 147-150.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 147-150
    • Zheng, W.1    Xie, D.W.2    Jin, F.3
  • 56
    • 0027359223 scopus 로고
    • Migration patterns and breast cancer risk in Asian-American women
    • Ziegler RG, Hoover RN, Pike MC, et al. (1993) Migration patterns and breast cancer risk in Asian-American women. J Natl Cancer Inst 85, 1819-1827.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1819-1827
    • Ziegler, R.G.1    Hoover, R.N.2    Pike, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.