Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate

Prostate

Volumn 37, Issue 1, 1998, Pages 36-43

  Dalu, Abraham ^a   Haskell, Joyce F ^a   Coward, Lori ^a   Lamartiniere, Coral A ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

EGF and ErbB2 Neu receptors; Genistein; Prostate; Rat

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GENISTEIN; ONCOPROTEIN; PHYTOESTROGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET; GENE EXPRESSION; MOLECULAR WEIGHT; NONHUMAN; ONCOGENE NEU; ORGAN WEIGHT; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR GENE; SIGNAL TRANSDUCTION; SOYBEAN; TESTOSTERONE BLOOD LEVEL;

ANIMALS; ANTICARCINOGENIC AGENTS; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENISTEIN; MALE; PROSTATIC NEOPLASMS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SOYBEANS;

EID: 0031880755     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19980915)37:1<36::AID-PROS6>3.0.CO;2-6     Document Type: Article

References (51)

1. Colditz GA, Frazier AL: Models of breast cancer show that risk is set by events of early life: Prevention efforts must shift focus. Cancer Epidemiol Biomarkers Prev 1995;4:567-571.
2. Armstrong BE, Doll R: Environmental factors and cancer incidence and mortality in different countries with special reference to dietary practices. Cancer 1975;15:617-631.
3. Zaridze DG, Boyle P, Smans M: International trends in prostatic cancer. Int J Cancer 1984;33:223-230.
4. Adlercreutz H, Honjo H, Higashi A, Fotsis T, Hamalainen E, Hasegawa T, Okada H: Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. Am J Clin Nutr 1991;54:1093-1100.
5. Dhom G: Epidemiology of hormone-dependent tumors. In Voigt KD, Knabbe C (eds): "Endocrine Dependent Tumors," New York: Raven Press, 1991:1-42.
6. Haenszel W, Kurihara M: Studies of Japanese migrants: I. Mortality from cancer and other diseases among Japanese in the United States. J Natl Cancer Inst 1968;40:43-68.
7. Shimizu H, Ross RK, Bernstein L, Yatani R, Henderson BE, Mack TM: Cancers of the breast and prostate among Japanese and white immigrants in Los Angeles County. Br J Cancer 1991; 63:963-966.
8. Morton MS, Chan PSF, Cheng C, Blacklock N, Matos-Ferreira A, Abranches-Monteiro L, Correia R, Lloyd S, Griffiths K: Lignans and isoflavonoids in plasma and prostatic fluid in men: Samples from Portugal, Hong Kong, and the United Kingdom. Prostate 1997;32:122-128.
9. Zhang JX, Hallmans G, Landstrom M, Bergh A, Damber JE, Aman P, Adlercreutz H: Soy and rye diets inhibit the development of Dunning R3327 prostatic adenocarcinoma in rats. Cancer Lett 1997;114:313-314.
10. Pollard M, Luckert PH: Influences of isoflavones in soy protein isolates on development of induced prostate-related cancers in L-W rats. Nutr Cancer 1997;28:41-45.
11. Coward L, Kirk M, Albin N, Barnes S: Analysis of plasma isoflavones by reversed-phase HPLC-multiple reaction ion monitoring-mass spectrometry. Clin Chim Acta 1996;247:121-142.
12. Shutt DA, Cox RI: Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro. J Endocrinol 1972;52:299-310.
13. Mathieson RA, Kitts WD: Binding of phyto-oestrogens and oestradiol-17 beta by cytoplasmic receptors in the pituitary gland and hypothalamus of the ewe. J Endocrinol 1980;85:317-325.
14. Martin PM, Horwitz KB, Ryan DS, McGuire WL: Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology 1978;103:1860-1867.
15. Makela S, Davis VL, Tally WC, Korkman J, Salo L, Vihko R, Santti R, Korach KS: Dietary estrogens act through estrogen receptor-mediated processes and show no antiestrogenicity in cultured breast cancer cells. Environ Health Perspect 1994;102: 572-578.
16. Cheng E, Story CD, Yoder Y, Hale WH, Burroughs W: Estrogenic activity of isoflavone derivative extracted and prepared for soybean oil meal. Science 1953;118:164-165.
17. Bickoff EM, Livingston AL, Hendrickson AP, Booth AN: Relative potencies of several estrogen-like compounds found in forages. J Agric Food Chem 1962;10:410-411.
18. Folman Y, Pope GS: The interaction in the immature mouse of potent oestrogens with coumestrol, genistein and other uterovaginotrophic compounds of low potency. J Endocrinol 1966;34: 215-225.
19. Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N, Shibuya M, Fukami Y: Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 1987;262:5592-5595.
20. Dean NM, Kanemitsu M, Boynton AL: Effects of the tyrosine-kinase inhibitor genistein on DNA synthesis and phospholipid-derived second messenger generation in mouse 10T1/2 fibroblasts and rat liver T51B cells. Biochem Biophys Res Commun 1989;165:795-801.
21. Trevillyan JM, Lu YL, Atluru D, Phillips CA, Bjorndahl JM: Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase. J Immunol 1990;145:3223-3230.
22. Tripathi YB, Lim RW, Fernandez-Gallardo S, Kandala JC, Guntaka RV, Shukla SD: Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells. Biochem J 1992;286:527-533.
23. Okura A, Arakawa H, Oka H, Yoshinari T, Monden Y: Effect of genistein on topoisomerase activity and on the growth of [VAL12] Ha-ras-transformed NIH 3T3 cells. Biochem Biophys Res Commun 1988;157:183-189.
24. Jha HC, von Recklinghausen G, Zilliken F: Inhibition of in vitro microsomal lipid peroxidation by isoflavonoids. Biochem Pharmacol 1985;34:1367-1369.
25. Fotsis T, Pepper M, Adlercreutz H, Fleischmann G, Hase T, Montesano R, Schweigerer L: Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc Natl Acad Sci USA 1993; 90:2690-2694.
26. Gyorgy P, Murata K, Ikehata H: Antioxidants isolated from fermented soybeans (tempeh). Nature 1964;203:870-872.
27. Pratt DE, Di Pietro C, Porter WL, Giffee JW: Phenolic antioxidants of soy protein hydrolyzates. J Food Sci 1982;47:24-25.
28. Wei H, Bowen R, Cai Q, Barnes S, Wang Y: Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med 1995;208:124-130.
29. Constantinou A, Kiguchi K, Huberman E: Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res 1990;50:26182624.
30. Kiguchi K, Constantinou AI, Huberman E: Genistein-induced cell differentiation and protein-linked DNA strand breakage in human melanoma cells. Cancer Commun 1990;2:271-277.
31. Watanabe T, Kondo K, Oishi M: Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of tyrosine protein kinases. Cancer Res 1991;51:764-768.
32. Kondo K, Tsuneizumi K, Watanabe T, Oishi M: Induction of in vitro differentiation of mouse embryonal carcinoma (F9) cells by inhibitors of topoisomerases. Cancer Res 1991;51:5398-5404.
33. Miller DR, Lee GM, Maness PF: Increased neurite outgrowth induced by inhibition of protein tyrosine kinase activity in PC12 pheochromocytoma cells. J Neurochem 1993;60:2134-2144.
34. Constantinou A, Huberman E: Genistein as an inducer of tumor cell differentiation: Possible mechanisms of action. Proc Soc Exp Biol Med 1995;208:109-115.
35. Lamartiniere CA, Moore JB, Brown NM, Thompson R, Hardin MJ, Barnes S: Genistein suppresses mammary cancer in rats. Carcinogenesis 1995;16:2833-2840.
36. Murrill WB, Brown NM, Zhang J-X, Manzolillo PA, Barnes S, Lamartiniere CA: Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats. Carcinogenesis 1996;17:1451-1457.
37. Uckun FM, Evans WE, Forsyth CJ, Waddick KG, Ahlgren LT, Chelstrom LM, Burkhardt A, Bolen J, Myers DE: Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases. Science 1995;267:886-891.
38. Schleicher R, Zheng M, Zhang M, Lamartiniere CA: Genistein inhibition of prostate cancer cell growth and metastasis in vivo (abstract). In Messina M (ed). "Second International Symposium on the Role of Soy in Preventing and Treating Chronic Disease," Brussels: 1996:47.
39. Price D: Comparative aspects of development and structures in the prostate. NCI Monogr 1963;12:1-18.
40. Pollard M: Spontaneous prostate adenocarcinomas in aged germ-free Wistar rats. J Natl Cancer Inst 1973;51:1235-1241.
41. Dalu A, Haskell J, Lamartiniere CA: Dietary genistein inhibits protein tyrosine phosphorylation in the dorsolateral prostate of the rat [abstract]. In: Messina M (ed) "Second International Symposium on the Role of Soy in Preventing and Treating Chronic Disease. 1996, Sept 15-18; Brussels. Belgium," Volume 2. 1996:47-48.
42. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
43. Azziz R, Bradley EL Jr, Potter HD, Parker CR Jr, Boots LR: Chronic hyperinsulinemia and the adrenal androgen response to acute corticotropin-(1-24) stimulation in hyperandrogenic women. Am J Obstet Gynecol 1995;172:1251-1256.
44. Luetteke NC, Phillips HK, Qiu TH, Copeland NG, Earp HS, Jenkins NA, Lee DC: The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev 1994;8:399-413.
45. Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL: Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235:177-182.
46. Carraway KL III, Cantley LC: A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling. Cell 1994;78:5-8.
47. King CR, Borrello I, Bellot F, Comoglio P, Schlessinger J: EGF binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3. EMBO J 1988;7:1647-1651.
48. Setchell KDR, Adlercreutz H: Mammalian lignans and phytooestrogens: Recent studies on their formation, metabolism and biological role in health and disease. In Rowland IA (ed): "The Role of Gut Microflora in Toxicity and Cancer," New York: Academic Press, 1988:315-345.
49. Adlercreutz H, Markkanen H, Watanabe S: Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 1993;342: 1209-1210.
50. Peterson G, Barnes S: Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation. Prostate 1993;22:335-345.
51. Adlercreutz H, Makela S, Pylkkanen L, Santti R, Kinzel J, van Reijsen M, Markkanen H, Kamarainen E-L, Watanabe S, Fotsis T, Wahala K, Makela S, Hase T: Dietary phytoestrogens and prostate cancer [abstract]. In: "86th Annual Meeting Proc Am Assoc Cancer Res;1995 March 18-22." Toronto: 1995. Extended Abstracts PP687.