Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast

American Journal of Clinical Nutrition

Volumn 68, Issue 6 SUPPL., 1998, Pages

  McMichael Phillips, Danielle F ^b   Harding, Claudia ^b   Morton, Mike ^b   Roberts, Stephen A ^b   Howell, Anthony ^b   Potten, Christopher S ^b   Bundred, Nigel J ^a  

^a MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^b NONE

Author keywords

Breast cancer; Daidzein; Genistein; Human breast; Ki67; Phytoestrogen; Premenopausal women; Soy; Thymidine labeling

Indexed keywords

DAIDZEIN; ENTERODIOL; ENTEROLACTONE; EQUOL; GENISTEIN; KI 67 ANTIGEN; PHYTOESTROGEN; PROGESTERONE RECEPTOR; SOYBEAN PROTEIN; THYMIDINE; TRITIUM;

ADULT; BREAST DISEASE; BREAST EPITHELIUM; CELL CYCLE S PHASE; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; ESTROGEN ACTIVITY; FEMALE; HUMAN; LABELING INDEX; PREMENOPAUSE; PROTEIN INTAKE; RANDOMIZED CONTROLLED TRIAL;

ANIMALIA; GLYCINE MAX; TRITIUM;

EID: 0031740854     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/68.6.1431S     Document Type: Conference Paper

References (38)

1. Adlercreutz H, Mousavi Y, Höckerstedt K. Diet and breast cancer. Acta Oncol 1992;31:175-81.
2. Adlercreutz H. Western diet and Western diseases: some hormonal and biochemical mechanisms and associations. Scand J Clin Lab Invest 1990;50(suppl):3-23.
3. Dunn JE. Cancer epidemiology in populations of the United States - with emphasis on Hawaii and California and Japan. Cancer Res 1975;35:3240-5.
4. Kolonel LN. Variability in diet and its relation to risk in ethnic and migrant groups. Basic Life Sci 1988;43:129-35.
5. Buell P. Changing incidence of breast cancer in Japanese-American women. J Natl Cancer Inst 1973;51:1479-83.
6. Wu AH, Ziegler RG, Nomura AMY, et al. Soy intake and risk of breast cancer in Asians and Asian Americans. Am J Clin Nutr 1998;68(suppl):1437S-43S.
7. Adlercreutz H, Honjo H, Higashi A, et al. Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. Am J Clin Nutr 1991;54:1093-100.
8. Setchell KDR, Borriello SP, Hulme P, Kirk DN, Axelson M. Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease. Am J Clin Nutr 1984;40:569-78.
9. Barnes S, Grubbs C, Setchell S, Carlson J. Soybeans inhibit mammary tumors in models of breast cancer. In: Pariza MW, Aeschbacher HU, Eton JS, Sato S, eds. Mutagens and carcinogens in the diet. Progress in clinical and biological research. New York: Wiley-Liss, 1990:239-53.
10. Lee HP, Gourley L, Duffy SW, Esteve J, Lee J, Day NE. Dietary effects on breast-cancer risk in Singapore. Lancet 1991; 337:1197-200.
11. Yuan J-M, Wang Q-S, Ross RK, Henderson BE, Yu MC. Diet and breast cancer in Shanghai and Tianjin, China. Br J Cancer 1995;71:1353-8.
12. Lu LW, Anderson KE, Grady JJ, Nagamani M. Effects of soya consumption for one month on steroid hormones in premenopausal women: implications for breast cancer risk reduction. Cancer Epidemiol Biomarkers Prev 1996;5:63-70.
13. Cassidy A, Bingham S, Setchell KDR. Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women. Am J Clin Nutr 1994;60:333-40.
14. Troll W, Wiesner R, Shellabarger J, Holtzman S, Stone JP. Soybean diet lowers breast tumour incidence in irradiated rats. Carcinogenesis 1980;1:469-72.
15. Axelson M, Sjövall J, Gustafsson BE, Setchell KDR. Soya - a dietary source of the non-steroidal oestrogen equol in man and animals. J Endocrinol 1984;102:49-56.
16. Thompson LU, Robb P, Serraino M, Cheung F. Mammalian lignan production from various foods. Nutr Cancer 1991;16:43-52.
17. Setchell KDR, Borriello SP, Gordon H, et al. Lignan formation in man - microbial involvement and possible roles in relation to cancer. Lancet 1981;2:4-7.
18. Adlercreutz H, Fotsis T, Heikkinene R, et al. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Lancet 1982;2:1298-9.
19. Adlercreutz H, Fotsis T, Bannwart C, et al. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. J Steroid Biochem 1986;25:791-7.
20. Hirano T, Oka K, Akiba M. Antiproliferative effects of synthetic and naturally occurring flavonoids on tumour cells of the human breast carcinoma cell line, ZR-75-1. Res Commun Chem Pathol Pharmacol 1989;64:69-77.
21. Paggliaci MC, Smacchia M, Migliorati G, Grignam F, Riccardi C, Nicoletti I. Growth-inhibitory effects of the natural phytoestrogen in MCF-7 human breast cancer cells. Eur J Cancer 1994; 30A:1675-82.
22. Martin PM, Horwitz KB, Ryan DS, McGuire WL. Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology 1978;103:1860-7.
23. Welshons WV, Murphy CS, Koch R, Calaf G, Jordan VC. Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol. Breast Cancer Res Treat 1987;10:169-75.
24. Lamartiniere CA, Moore J, Holland M, Barnes S. Neonatal genistein chemoprevents mammary cancer. Soc Exp Biol Med 1995;208:120-3.
25. Wang W, Tanaka Y, Han Z, Higuchi CM. Proliferative response of mammary glandular tissue to formononetin. Nutr Cancer 1995;23:131-40.
26. Bromley M, Rew D, Becciolini A, et al. A comparison of proliferation markers (Brd Urd, Ki-67, PCNA) determined at each cell position in the crypts of normal human colonic mucosa. Eur J Histochem 1996;40:89-100.
27. Laidlaw IJ, Clarke RB, Howell A, Owen AWMC, Potten CS, Anderson E. The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone. Endocrinology 1995;136:64-70.
28. Russo J, Gusterson BA, Rogers AE, Russo IH, Wellings SR, van Zweiten MJ. Comparative study of human and rat mammary tumorigenesis. Lab Invest 1990;62:244-78.
29. Howell A. Clinical evidence for the involvement of oestrogen in the development and progression of breast cancer. Proc R Soc Edinb [Biol] 1989;95:49-57.
30. Potten CS, Watson RJ, Williams GT, et al. The effect of age and menstrual cycle upon proliferative activity of the normal human breast. Br J Cancer 1988;58:163-70.
31. Williams G, Anderson E, Howell A, et al. Oral contraceptive (OCP) use increases proliferation and decreases oestrogen receptor content of epithelial cells in the normal human breast. Int J Cancer 1991;48:206-10.
32. Horwitz KB, McGuire WL. Estrogen control of progesterone receptor in human breast cancer. J Biol Chem 1978;253:2223-8.
33. Sathyamoorthy N, Wang TTY, Phang JM. Stimulation of pS2 expression by diet-derived compounds. Cancer Res 1994; 54:957-61.
34. Molteni A, Brizio-Molteni L, Persky V. In vitro hormonal effects of soybean isoflavones. J Nutr 1995;125:751S-6S.
35. Baird DD, Umbach DM, Landsell L, et al. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. J Clin Endocrinol Metab 1995;80:1685-90.
36. Wilcox G, Wahlqvist ML, Burger HG, Medley G. Oestrogenic effects of plant foods in postmenopausal women. Br Med J 1990;310:905-6.
37. Xu X, Harris KS, Wang H, Murphy PA, Hendrich S. Bioavailability of soybean isoflavones depends upon gut microflora in women. J Nutr 1995;125:2307-15.
38. Kirkman LM, Lampe JW, Campbell, DR, Martini MC, Slavin JL. Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets. Nutr Cancer 1995;24:1-12.