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Volumn 5, Issue 10, 2006, Pages 1819-1829

Proteomics in clinical trials and practice: Present uses and future promise

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTINEOPLASTIC AGENT; APOLIPOPROTEIN A1; APOLIPOPROTEIN A4; BEVACIZUMAB; BRCA1 PROTEIN; CA 125 ANTIGEN; CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CATHEPSIN D; GEFITINIB; HEAT SHOCK PROTEIN 70; IMATINIB; MAMMALIAN TARGET OF RAPAMYCIN; PREALBUMIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN TYROSINE KINASE INHIBITOR; PROTEOME; PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; SORAFENIB; SYNAPTOPHYSIN ALPHA ACTIVATOR; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 33750612372     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.R600008-MCP200     Document Type: Review
Times cited : (79)

References (65)
  • 1
    • 33646259958 scopus 로고    scopus 로고
    • Clinical proteomics: Searching for better tumour markers with SELDI-TOF mass spectrometry
    • Engwegen, J. Y., Gast, M. C., Schellens, J. H., and Beijnen, J. H. (2006) Clinical proteomics: searching for better tumour markers with SELDI-TOF mass spectrometry. Trends Pharmacol. Sci. 27, 251-259
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 251-259
    • Engwegen, J.Y.1    Gast, M.C.2    Schellens, J.H.3    Beijnen, J.H.4
  • 2
    • 3342902085 scopus 로고    scopus 로고
    • Clinical proteomics: Applications for prostate cancer biomarker discovery and detection
    • Petricoin, E. F., Ornstein, D. K., and Liotta, L. A. (2004) Clinical proteomics: Applications for prostate cancer biomarker discovery and detection. Urol. Oncol. 22, 322-328
    • (2004) Urol. Oncol. , vol.22 , pp. 322-328
    • Petricoin, E.F.1    Ornstein, D.K.2    Liotta, L.A.3
  • 4
    • 16544392954 scopus 로고    scopus 로고
    • Human genome: End of the beginning
    • Stein, L. D. (2004) Human genome: end of the beginning. Nature 431, 915-916
    • (2004) Nature , vol.431 , pp. 915-916
    • Stein, L.D.1
  • 5
    • 0035751374 scopus 로고    scopus 로고
    • Traditional and newer pathologic factors
    • Schnitt, S. J. (2001) Traditional and newer pathologic factors. J. Natl. Cancer Inst. Monogr. 30, 22-26
    • (2001) J. Natl. Cancer Inst. Monogr. , vol.30 , pp. 22-26
    • Schnitt, S.J.1
  • 6
    • 0031031582 scopus 로고    scopus 로고
    • Tumor-related prognostic factors for breast cancer
    • Donegan, W. L. (1997) Tumor-related prognostic factors for breast cancer. CA Cancer J. Clin. 47, 28-51
    • (1997) CA Cancer J. Clin. , vol.47 , pp. 28-51
    • Donegan, W.L.1
  • 7
    • 24044486897 scopus 로고    scopus 로고
    • Clinical cancer proteomics: Promises and pitfalls
    • Alalya, A., Al-Mohanna, M., and Linder, S. (2005) Clinical cancer proteomics: promises and pitfalls. J. Proteome Res. 4, 1213-1222
    • (2005) J. Proteome Res. , vol.4 , pp. 1213-1222
    • Alalya, A.1    Al-Mohanna, M.2    Linder, S.3
  • 9
    • 20544462907 scopus 로고    scopus 로고
    • Application of proteomics in the study of tumor metastasis
    • Cai, Z., Chiu, J. F., and He, Q. Y. (2004) Application of proteomics in the study of tumor metastasis. Genomics Proteomics Bioinformatics 2, 152-166
    • (2004) Genomics Proteomics Bioinformatics , vol.2 , pp. 152-166
    • Cai, Z.1    Chiu, J.F.2    He, Q.Y.3
  • 12
    • 33645813378 scopus 로고    scopus 로고
    • Mass spectrometry and protein analysis
    • Domon, B., and Aebersold, R. (2006) Mass spectrometry and protein analysis. Science 312, 212-217
    • (2006) Science , vol.312 , pp. 212-217
    • Domon, B.1    Aebersold, R.2
  • 16
    • 12444310169 scopus 로고    scopus 로고
    • Haptoglobin-α subunit as potential serum biomarker in ovarian cancer: Identification and characterization using proteomic profiling and mass spectrometry
    • Ye, B., Cramer, D. W., Skates, S. J., Gygi, S. P., Pratomo, V., Fu, L., Horick, N. K., Licklider, L. J., Schorge, J. O., Berkowitz, R. S., and Mok, S. C. (2003) Haptoglobin-α subunit as potential serum biomarker in ovarian cancer: Identification and characterization using proteomic profiling and mass spectrometry. Clin. Cancer Res. 9, 2904-2911
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2904-2911
    • Ye, B.1    Cramer, D.W.2    Skates, S.J.3    Gygi, S.P.4    Pratomo, V.5    Fu, L.6    Horick, N.K.7    Licklider, L.J.8    Schorge, J.O.9    Berkowitz, R.S.10    Mok, S.C.11
  • 22
    • 0036324715 scopus 로고    scopus 로고
    • Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer
    • Li, J., Zhang, Z., Rosenzweig, J., Wang, Y. Y., and Chan, D. W. (2002) Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer. Clin. Chem. 48, 1296-1304
    • (2002) Clin. Chem. , vol.48 , pp. 1296-1304
    • Li, J.1    Zhang, Z.2    Rosenzweig, J.3    Wang, Y.Y.4    Chan, D.W.5
  • 23
    • 33645268110 scopus 로고    scopus 로고
    • Diagnostic application of serum protein pattern and artificial neural network software in breast cancer
    • Hu, Y., Zhang, S. Z., Yu, J. K., Liu, J., Zheng, S., and Hu, X. (2005) Diagnostic application of serum protein pattern and artificial neural network software in breast cancer. Ai Zheng 24, 67-71
    • (2005) Ai Zheng , vol.24 , pp. 67-71
    • Hu, Y.1    Zhang, S.Z.2    Yu, J.K.3    Liu, J.4    Zheng, S.5    Hu, X.6
  • 24
    • 1542378202 scopus 로고    scopus 로고
    • Analysis of serum proteomic patterns for early cancer diagnosis: Drawing attention to potential problems
    • Diamandis, E. P. (2004) Analysis of serum proteomic patterns for early cancer diagnosis: drawing attention to potential problems. J. Natl. Cancer Inst 96, 353-356
    • (2004) J. Natl. Cancer Inst , vol.96 , pp. 353-356
    • Diamandis, E.P.1
  • 26
    • 16544370448 scopus 로고    scopus 로고
    • Surfaced-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) differentiation of serum protein profiles of BRCA-1 and sporadic breast cancer
    • Becker, S., Cazares, L. H., Watson, P., Lynch, H., Semmes, O. J., Drake, R. R., and Laronga, C. (2004) Surfaced-enhanced laser desorption/ ionization time-of-flight (SELDI-TOF) differentiation of serum protein profiles of BRCA-1 and sporadic breast cancer. Ann. Surg. Oncol. 11, 907-914
    • (2004) Ann. Surg. Oncol. , vol.11 , pp. 907-914
    • Becker, S.1    Cazares, L.H.2    Watson, P.3    Lynch, H.4    Semmes, O.J.5    Drake, R.R.6    Laronga, C.7
  • 27
    • 11144356366 scopus 로고    scopus 로고
    • Characterization of the human urinary proteome: A method for high-resolution display of urinary proteins on two-dimensional electrophoresis gels with a yield of nearly 1400 distinct protein spots
    • Pieper, R., Gatlin, C. L., McGrath, A. M., Makusky, A. J., Mondal, M., Seonarain, M., Field, E., Schatz, C. R., Estock, M. A., Ahmed, N., Anderson, N. G., and Steiner, S. (2004) Characterization of the human urinary proteome: a method for high-resolution display of urinary proteins on two-dimensional electrophoresis gels with a yield of nearly 1400 distinct protein spots. Proteomics 4, 1159-1174
    • (2004) Proteomics , vol.4 , pp. 1159-1174
    • Pieper, R.1    Gatlin, C.L.2    McGrath, A.M.3    Makusky, A.J.4    Mondal, M.5    Seonarain, M.6    Field, E.7    Schatz, C.R.8    Estock, M.A.9    Ahmed, N.10    Anderson, N.G.11    Steiner, S.12
  • 28
  • 29
    • 11144356519 scopus 로고    scopus 로고
    • Identification by proteomic analysis of calreticulin as a marker for bladder cancer and evaluation of the diagnostic accuracy of its detection in urine
    • Kageyama, S., Isono, T., Iwaki, H., Wakabayashi, Y., Okada, Y., Kontani, K., Yoshimura, K., Terai, A., Arai, Y., and Yoshiki, T. (2004) Identification by proteomic analysis of calreticulin as a marker for bladder cancer and evaluation of the diagnostic accuracy of its detection in urine. Clin. Chem. 50, 857-866
    • (2004) Clin. Chem. , vol.50 , pp. 857-866
    • Kageyama, S.1    Isono, T.2    Iwaki, H.3    Wakabayashi, Y.4    Okada, Y.5    Kontani, K.6    Yoshimura, K.7    Terai, A.8    Arai, Y.9    Yoshiki, T.10
  • 33
    • 33645776682 scopus 로고    scopus 로고
    • Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects
    • Castaño, E. M., Roher, A. E., Esh, C. L., Kokjohn, T. A., and Beach, T. (2006) Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects. Neurol. Res. 28, 155-163
    • (2006) Neurol. Res. , vol.28 , pp. 155-163
    • Castaño, E.M.1    Roher, A.E.2    Esh, C.L.3    Kokjohn, T.A.4    Beach, T.5
  • 35
  • 38
    • 0035666963 scopus 로고    scopus 로고
    • Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: Potential for new biomarkers to aid in the diagnosis of breast cancer
    • Paweletz, C. P., Trock, B., Pennanen, M., Tsangaris, T., Magnant, C., Liotta, L. A., and Petricoin, E. F., III (2001) Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: potential for new biomarkers to aid in the diagnosis of breast cancer. Dis. Markers 17, 301-307
    • (2001) Dis. Markers , vol.17 , pp. 301-307
    • Paweletz, C.P.1    Trock, B.2    Pennanen, M.3    Tsangaris, T.4    Magnant, C.5    Liotta, L.A.6    Petricoin III, E.F.7
  • 42
    • 33644939782 scopus 로고    scopus 로고
    • Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway
    • Luo, F., Liu, X., Yan, N., Li, S., Cao, G., Cheng, Q., Xia, Q., and Wang, H. (2006) Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway. BMC Cancer 6, 26
    • (2006) BMC Cancer , vol.6 , pp. 26
    • Luo, F.1    Liu, X.2    Yan, N.3    Li, S.4    Cao, G.5    Cheng, Q.6    Xia, Q.7    Wang, H.8
  • 43
    • 28644439593 scopus 로고    scopus 로고
    • Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer
    • Zhang, D., Tal, L. K., Wong, L. L., Chiu, L. L., Sethi, S. K., and Koay, E. S. (2005) Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer. Mol. Cell. Proteomics 4, 1686-1696
    • (2005) Mol. Cell. Proteomics , vol.4 , pp. 1686-1696
    • Zhang, D.1    Tal, L.K.2    Wong, L.L.3    Chiu, L.L.4    Sethi, S.K.5    Koay, E.S.6
  • 44
    • 4444342914 scopus 로고    scopus 로고
    • Two proliferation-related proteins, TYMS and PGK1, could be new cytotoxic T lymphocyte-directed tumor-associated antigens of HLA-A2+ colon cancer
    • Shichijo, S., Azuma, K., Komatsu, N., Ito, M., Maeda, Y., Ishihara, Y., and Itoh, K. (2004) Two proliferation-related proteins, TYMS and PGK1, could be new cytotoxic T lymphocyte-directed tumor-associated antigens of HLA-A2+ colon cancer. Clin. Cancer Res. 10, 5828-5836
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5828-5836
    • Shichijo, S.1    Azuma, K.2    Komatsu, N.3    Ito, M.4    Maeda, Y.5    Ishihara, Y.6    Itoh, K.7
  • 45
    • 33646739504 scopus 로고    scopus 로고
    • Identification of differentially expressed proteins in colorectal cancer by proteomics: Down-regulation of secretagogin
    • Xing, X., Lai, M., Gartner, W., Xu, E., Huang, Q., Li, H., and Chen, G. (2006) Identification of differentially expressed proteins in colorectal cancer by proteomics: down-regulation of secretagogin. Proteomics 6, 2916-2923
    • (2006) Proteomics , vol.6 , pp. 2916-2923
    • Xing, X.1    Lai, M.2    Gartner, W.3    Xu, E.4    Huang, Q.5    Li, H.6    Chen, G.7
  • 49
    • 2442455834 scopus 로고    scopus 로고
    • Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors
    • Brehmer, D., Godl, K., Zech, B., Wissing, J., and Daub, H. (2004) Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol. Cell. Proteomics 3, 490-500
    • (2004) Mol. Cell. Proteomics , vol.3 , pp. 490-500
    • Brehmer, D.1    Godl, K.2    Zech, B.3    Wissing, J.4    Daub, H.5
  • 51
    • 2942558439 scopus 로고    scopus 로고
    • Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells
    • Parmar, S., Katsoulidis, E., Verma, A., Li, Y., Sassano, A., Lal, L., Majchrzak, B., Ravandi, F., Tallman, M. S., Fish, E. N., and Platanias, L. C. (2004) Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells. J. Biol. Chem. 279, 25345-25352
    • (2004) J. Biol. Chem. , vol.279 , pp. 25345-25352
    • Parmar, S.1    Katsoulidis, E.2    Verma, A.3    Li, Y.4    Sassano, A.5    Lal, L.6    Majchrzak, B.7    Ravandi, F.8    Tallman, M.S.9    Fish, E.N.10    Platanias, L.C.11
  • 52
    • 18844445319 scopus 로고    scopus 로고
    • The molecular make-up of a tumour: Proteomics in cancer research
    • Kolch, W., Mischak, H., and Pitt, A. R. (2005) The molecular make-up of a tumour: proteomics in cancer research. Clin. Sci. (Lond.) 108, 369-383
    • (2005) Clin. Sci. (Lond.) , vol.108 , pp. 369-383
    • Kolch, W.1    Mischak, H.2    Pitt, A.R.3
  • 53
  • 54
    • 0036254631 scopus 로고    scopus 로고
    • Increased expression of heat shock protein 70 in adherent ovarian cancer and mesothelioma following treatment with manumycin, a farnesyl transferase inhibitor
    • Hu, W., Wu, W., Yeung, S. C., Freedman, R. S., Kavanagh, J. J., and Verschraegen, C. F. (2002) Increased expression of heat shock protein 70 in adherent ovarian cancer and mesothelioma following treatment with manumycin, a farnesyl transferase inhibitor. Anticancer Res. 22, 665-672
    • (2002) Anticancer Res. , vol.22 , pp. 665-672
    • Hu, W.1    Wu, W.2    Yeung, S.C.3    Freedman, R.S.4    Kavanagh, J.J.5    Verschraegen, C.F.6
  • 55
    • 24144490686 scopus 로고    scopus 로고
    • Proteomics in acute myelogenous leukaemia (AML): Methodological strategies and identification of protein targets for novel antileukaemic therapy
    • Sjoholt, G., Anensen, N., Wergeland, L., Mc Cormack, E., Bruserud, O., and Gjertsen, B. T. (2005) Proteomics in acute myelogenous leukaemia (AML): methodological strategies and identification of protein targets for novel antileukaemic therapy. Curr. Drug Targets 6, 631-646
    • (2005) Curr. Drug Targets , vol.6 , pp. 631-646
    • Sjoholt, G.1    Anensen, N.2    Wergeland, L.3    McCormack, E.4    Bruserud, O.5    Gjertsen, B.T.6
  • 56
    • 21344442130 scopus 로고    scopus 로고
    • Proteomic approaches in colon cancer: Promising tools for new cancer markers and drug target discovery
    • Alessandro, R., Belluco, C., and Kohn, E. C. (2005) Proteomic approaches in colon cancer: promising tools for new cancer markers and drug target discovery. Clin. Colorectal Cancer 4, 396-402
    • (2005) Clin. Colorectal Cancer , vol.4 , pp. 396-402
    • Alessandro, R.1    Belluco, C.2    Kohn, E.C.3
  • 57
    • 2542612884 scopus 로고    scopus 로고
    • Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: A novel resource for biomarker and therapeutic target discovery
    • Celis, J. E., Gromov, P., Cabezon, T., Moreira, J. M., Ambartsumian, N., Sandelin, K., Rank, F., and Gromova, I. (2004) Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: a novel resource for biomarker and therapeutic target discovery. Mol. Cell. Proteomics 3, 327-344
    • (2004) Mol. Cell. Proteomics , vol.3 , pp. 327-344
    • Celis, J.E.1    Gromov, P.2    Cabezon, T.3    Moreira, J.M.4    Ambartsumian, N.5    Sandelin, K.6    Rank, F.7    Gromova, I.8
  • 58
    • 7044274430 scopus 로고    scopus 로고
    • Proteomics for hepatocellular carcinoma marker discovery
    • Chignard, N., and Beretta, L. (2004) Proteomics for hepatocellular carcinoma marker discovery. Gastroenterology 127, Suppl. 1, S120-S125
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL. 1
    • Chignard, N.1    Beretta, L.2
  • 61
    • 0035860969 scopus 로고    scopus 로고
    • Clinical proteomics: Personalized molecular medicine
    • Liotta, L. A., Kohn, E. C., and Petricoin, E. F. (2001) Clinical proteomics: personalized molecular medicine. J. Am. Med. Assoc. 286, 2211-2214
    • (2001) J. Am. Med. Assoc. , vol.286 , pp. 2211-2214
    • Liotta, L.A.1    Kohn, E.C.2    Petricoin, E.F.3


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