-
1
-
-
0031765381
-
Role of fimbriae-mediated adherence for neutrophil migration across Escherichia coli-infected epithelial cell layers
-
Godaly G., Frendeus B, Proudfoot A, Svensson M, Klemm P, Svanborg C. Role of fimbriae-mediated adherence for neutrophil migration across Escherichia coli-infected epithelial cell layers. Mol Microbiol 1998 30: 725 735.
-
(1998)
Mol Microbiol
, vol.30
, pp. 725-735
-
-
Godaly, G.1
Frendeus, B.2
Proudfoot, A.3
Svensson, M.4
Klemm, P.5
Svanborg, C.6
-
2
-
-
0031461206
-
Epithelial cells as sensors for microbial infection
-
Kagnoff MF, Eckmann L. Epithelial cells as sensors for microbial infection. J Clin Invest 1997 100: 6 10.
-
(1997)
J Clin Invest
, vol.100
, pp. 6-10
-
-
Kagnoff, M.F.1
Eckmann, L.2
-
3
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996 86: 973 983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
4
-
-
0024299087
-
The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
-
Hashimoto C, Hudson KL, Anderson KV. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 1988 52: 269 279.
-
(1988)
Cell
, vol.52
, pp. 269-279
-
-
Hashimoto, C.1
Hudson, K.L.2
Anderson, K.V.3
-
6
-
-
0031446642
-
Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B, Reichhart JM, Hoffmann JA. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci USA 1997 94: 14614 14619.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B.1
Reichhart, J.M.2
Hoffmann, J.A.3
-
7
-
-
22144452520
-
The evolution of vertebrate Toll-like receptors
-
Roach JC, Glusman G, Rowen L, Kaur A, Purcell MK, Smith KD et al. The evolution of vertebrate Toll-like receptors. Proc Natl Acad Sci USA 2005 102: 9577 9582.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9577-9582
-
-
Roach, J.C.1
Glusman, G.2
Rowen, L.3
Kaur, A.4
Purcell, M.K.5
Smith, K.D.6
-
8
-
-
0025774776
-
Drosophila Toll and IL-1 receptor
-
Gay NJ, Keith FJ. Drosophila Toll and IL-1 receptor. Nature 1991 351: 355 356.
-
(1991)
Nature
, vol.351
, pp. 355-356
-
-
Gay, N.J.1
Keith, F.J.2
-
9
-
-
23044445303
-
Crystal structure of human toll-like receptor 3 (TLR3) ectodomain
-
Choe J, Kelker MS, Wilson IA. Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science 2005 309: 581 585.
-
(2005)
Science
, vol.309
, pp. 581-585
-
-
Choe, J.1
Kelker, M.S.2
Wilson, I.A.3
-
10
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
Kobe B, Kajava AV. The leucine-rich repeat as a protein recognition motif. Curr Opin Struct Biol 2001 11: 725 732.
-
(2001)
Curr Opin Struct Biol
, vol.11
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
11
-
-
2942627626
-
Hydrophobicity: An ancient damage-associated molecular pattern that initiates innate immune responses
-
Seong SY, Matzinger P. Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol 2004 4: 469 478.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 469-478
-
-
Seong, S.Y.1
Matzinger, P.2
-
12
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M, Ogata M, Iwakura Y, Akira S et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol 2002 3: 667 672.
-
(2002)
Nat Immunol
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
-
13
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999 189: 1777 1782.
-
(1999)
J Exp Med
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
-
14
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990 249: 1431 1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
15
-
-
0036672050
-
TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14
-
Backhed F, Meijer L, Normark S, Richter-Dahlfors A. TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14. Cell Microbiol 2002 4: 493 501.
-
(2002)
Cell Microbiol
, vol.4
, pp. 493-501
-
-
Backhed, F.1
Meijer, L.2
Normark, S.3
Richter-Dahlfors, A.4
-
16
-
-
4344627821
-
Endogenous ligands of Toll-like receptors
-
Tsan MF, Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol 2004 76: 514 519.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 514-519
-
-
Tsan, M.F.1
Gao, B.2
-
17
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
-
Ohashi K, Burkart V, Flohe S, Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000 164: 558 561.
-
(2000)
J Immunol
, vol.164
, pp. 558-561
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
18
-
-
0037177825
-
Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
-
Asea A, Rehli M, Kabingu E, Boch JA, Bare O, Auron PE et al. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 2002 277: 15028 15034.
-
(2002)
J Biol Chem
, vol.277
, pp. 15028-15034
-
-
Asea, A.1
Rehli, M.2
Kabingu, E.3
Boch, J.A.4
Bare, O.5
Auron, P.E.6
-
19
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot L, Balloy V, McCormack FX, Golenbock DT, Chignard M, Si-Tahar M. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J Immunol 2002 168: 5989 5992.
-
(2002)
J Immunol
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
Si-Tahar, M.6
-
20
-
-
0034669971
-
Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides
-
Tapping RI, Akashi S, Miyake K, Godowski PJ, Tobias PS. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides. J Immunol 2000 165: 5780 5787.
-
(2000)
J Immunol
, vol.165
, pp. 5780-5787
-
-
Tapping, R.I.1
Akashi, S.2
Miyake, K.3
Godowski, P.J.4
Tobias, P.S.5
-
21
-
-
0034662239
-
Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
-
Hirschfeld M, Ma Y, Weis JH, Vogel SN, Weis JJ. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 2000 165: 618 622.
-
(2000)
J Immunol
, vol.165
, pp. 618-622
-
-
Hirschfeld, M.1
Ma, Y.2
Weis, J.H.3
Vogel, S.N.4
Weis, J.J.5
-
22
-
-
7944220803
-
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition
-
Travassos LH, Girardin SE, Philpott DJ, Blanot D, Nahori MA, Werts C et al. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep 2004 5: 1000 1006.
-
(2004)
EMBO Rep
, vol.5
, pp. 1000-1006
-
-
Travassos, L.H.1
Girardin, S.E.2
Philpott, D.J.3
Blanot, D.4
Nahori, M.A.5
Werts, C.6
-
23
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H, Henzel WJ, Shillinglaw W, Li S, Cao Z. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 1997 7: 837 847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
24
-
-
0034597766
-
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
-
Xu Y, Tao X, Shen B, Horng T, Medzhitov R, Manley JL et al. Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature 2000 408: 111 115.
-
(2000)
Nature
, vol.408
, pp. 111-115
-
-
Xu, Y.1
Tao, X.2
Shen, B.3
Horng, T.4
Medzhitov, R.5
Manley, J.L.6
-
25
-
-
0034681434
-
Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways
-
Slack JL, Schooley K, Bonnert TP, Mitcham JL, Qwarnstrom EE, Sims JE et al. Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways. J Biol Chem 2000 275: 4670 4678.
-
(2000)
J Biol Chem
, vol.275
, pp. 4670-4678
-
-
Slack, J.L.1
Schooley, K.2
Bonnert, T.P.3
Mitcham, J.L.4
Qwarnstrom, E.E.5
Sims, J.E.6
-
26
-
-
0033583034
-
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
-
Zhang FX, Kirschning CJ, Mancinelli R, Xu XP, Jin Y, Faure E et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem 1999 274: 7611 7614.
-
(1999)
J Biol Chem
, vol.274
, pp. 7611-7614
-
-
Zhang, F.X.1
Kirschning, C.J.2
Mancinelli, R.3
Xu, X.P.4
Jin, Y.5
Faure, E.6
-
27
-
-
0036087432
-
CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells
-
Li H, Nord EP. CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells. Am J Physiol Renal Physiol 2002 282: F1020 F1033.
-
(2002)
Am J Physiol Renal Physiol
, vol.282
-
-
Li, H.1
Nord, E.P.2
-
28
-
-
0033634977
-
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
-
Takaesu G, Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K et al. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell 2000 5: 649 658.
-
(2000)
Mol Cell
, vol.5
, pp. 649-658
-
-
Takaesu, G.1
Kishida, S.2
Hiyama, A.3
Yamaguchi, K.4
Shibuya, H.5
Irie, K.6
-
29
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L, Wang C, Spencer E, Yang L, Braun A, You J et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 2000 103: 351 361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
-
30
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 2001 412: 346 351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
31
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002 420: 324 329.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
-
32
-
-
0346157331
-
TIR domain-containing adaptors define the specificity of TLR signaling
-
Yamamoto M, Takeda K, Akira S. TIR domain-containing adaptors define the specificity of TLR signaling. Mol Immunol 2004 40: 861 868.
-
(2004)
Mol Immunol
, vol.40
, pp. 861-868
-
-
Yamamoto, M.1
Takeda, K.2
Akira, S.3
-
33
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999 11: 115 122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
34
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003 301: 640 643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
-
35
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T et al. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 2003 4: 1144 1150.
-
(2003)
Nat Immunol
, vol.4
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
-
36
-
-
0141959224
-
LPS-TLR4 signaling to IRF-3/7 and NF-{kappa}B involves the Toll adapters TRAM and TRIF
-
Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E et al. LPS-TLR4 signaling to IRF-3/7 and NF-{kappa}B involves the Toll adapters TRAM and TRIF. J Exp Med 2003 198: 1043 1055.
-
(2003)
J Exp Med
, vol.198
, pp. 1043-1055
-
-
Fitzgerald, K.A.1
Rowe, D.C.2
Barnes, B.J.3
Caffrey, D.R.4
Visintin, A.5
Latz, E.6
-
37
-
-
0037471003
-
Pyogenic bacterial infections in humans with IRAK-4 deficiency
-
Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003 299: 2076 2079.
-
(2003)
Science
, vol.299
, pp. 2076-2079
-
-
Picard, C.1
Puel, A.2
Bonnet, M.3
Ku, C.L.4
Bustamante, J.5
Yang, K.6
-
38
-
-
0043281537
-
Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections
-
Medvedev AE, Lentschat A, Kuhns DB, Blanco JC, Salkowski C, Zhang S et al. Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections. J Exp Med 2003 198: 521 531.
-
(2003)
J Exp Med
, vol.198
, pp. 521-531
-
-
Medvedev, A.E.1
Lentschat, A.2
Kuhns, D.B.3
Blanco, J.C.4
Salkowski, C.5
Zhang, S.6
-
39
-
-
1042269515
-
The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease
-
Ogus AC, Yoldas B, Ozdemir T, Uguz A, Olcen S, Keser I et al. The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease. Eur Respir J 2004 23: 219 223.
-
(2004)
Eur Respir J
, vol.23
, pp. 219-223
-
-
Ogus, A.C.1
Yoldas, B.2
Ozdemir, T.3
Uguz, A.4
Olcen, S.5
Keser, I.6
-
40
-
-
33746895147
-
An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation
-
Cerchia L, D'Alessio A, Amabile G, Duconge F, Pestourie C, Tavitian B et al. An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation. Mol Cancer Res 2006 4: 481 488.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 481-488
-
-
Cerchia, L.1
D'Alessio, A.2
Amabile, G.3
Duconge, F.4
Pestourie, C.5
Tavitian, B.6
-
41
-
-
0035818268
-
Exposure to farming in early life and development of asthma and allergy: A cross-sectional survey
-
Riedler J, Braun-Fahrlander C, Eder W, Schreuer M, Waser M, Maisch S et al. Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey. Lancet 2001 358: 1129 1133.
-
(2001)
Lancet
, vol.358
, pp. 1129-1133
-
-
Riedler, J.1
Braun-Fahrlander, C.2
Eder, W.3
Schreuer, M.4
Waser, M.5
Maisch, S.6
-
42
-
-
21644434827
-
Expression of TLR2 and TLR4 messenger RNA in the epithelial cells of the nasal airway
-
Dong Z, Yang Z, Wang C. Expression of TLR2 and TLR4 messenger RNA in the epithelial cells of the nasal airway. Am J Rhinol 2005 19: 236 239.
-
(2005)
Am J Rhinol
, vol.19
, pp. 236-239
-
-
Dong, Z.1
Yang, Z.2
Wang, C.3
-
43
-
-
0042672616
-
Human beta-defensins and toll-like receptors in the upper airway
-
Claeys S, de Belder T, Holtappels G, Gevaert P, Verhasselt B, Van Cauwenberge P et al. Human beta-defensins and toll-like receptors in the upper airway. Allergy 2003 58: 748 753.
-
(2003)
Allergy
, vol.58
, pp. 748-753
-
-
Claeys, S.1
De Belder, T.2
Holtappels, G.3
Gevaert, P.4
Verhasselt, B.5
Van Cauwenberge, P.6
-
44
-
-
4143090418
-
Expression of functional toll-like receptor-2 and -4 on alveolar epithelial cells
-
Armstrong L, Medford AR, Uppington KM, Robertson J, Witherden IR, Tetley TD et al. Expression of functional toll-like receptor-2 and -4 on alveolar epithelial cells. Am J Respir Cell Mol Biol 2004 31: 241 245.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 241-245
-
-
Armstrong, L.1
Medford, A.R.2
Uppington, K.M.3
Robertson, J.4
Witherden, I.R.5
Tetley, T.D.6
-
45
-
-
16344389339
-
Toll-like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis
-
Hauber HP, Tulic MK, Tsicopoulos A, Wallaert B, Olivenstein R, Daigneault P et al. Toll-like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis. Can Respir J 2005 12: 13 18.
-
(2005)
Can Respir J
, vol.12
, pp. 13-18
-
-
Hauber, H.P.1
Tulic, M.K.2
Tsicopoulos, A.3
Wallaert, B.4
Olivenstein, R.5
Daigneault, P.6
-
46
-
-
29144532165
-
Characterization of Toll-like receptors in primary lung epithelial cells: Strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response
-
Ritter M, Mennerich D, Weith A, Seither P. Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response. J Inflamm (Lond) 2005 2: 16.
-
(2005)
J Inflamm (Lond)
, vol.2
, pp. 16
-
-
Ritter, M.1
Mennerich, D.2
Weith, A.3
Seither, P.4
-
47
-
-
4444292595
-
Activation of airway epithelial cells by toll-like receptor agonists
-
Sha Q, Truong-Tran AQ, Plitt JR, Beck LA, Schleimer RP. Activation of airway epithelial cells by toll-like receptor agonists. Am J Respir Cell Mol Biol 2004 31: 358 364.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 358-364
-
-
Sha, Q.1
Truong-Tran, A.Q.2
Plitt, J.R.3
Beck, L.A.4
Schleimer, R.P.5
-
48
-
-
2942544512
-
Toll-like receptors in normal and cystic fibrosis airway epithelial cells
-
Muir A, Soong G, Sokol S, Reddy B, Gomez MI, Van Heeckeren A et al. Toll-like receptors in normal and cystic fibrosis airway epithelial cells. Am J Respir Cell Mol Biol 2004 30: 777 783.
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, pp. 777-783
-
-
Muir, A.1
Soong, G.2
Sokol, S.3
Reddy, B.4
Gomez, M.I.5
Van Heeckeren, A.6
-
49
-
-
0347362785
-
Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin
-
Monick MM, Yarovinsky TO, Powers LS, Butler NS, Carter AB, Gudmundsson G et al. Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin. J Biol Chem 2003 278: 53035 53044.
-
(2003)
J Biol Chem
, vol.278
, pp. 53035-53044
-
-
Monick, M.M.1
Yarovinsky, T.O.2
Powers, L.S.3
Butler, N.S.4
Carter, A.B.5
Gudmundsson, G.6
-
50
-
-
3242708716
-
Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2
-
Jia HP, Kline JN, Penisten A, Apicella MA, Gioannini TL, Weiss J et al. Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2. Am J Physiol Lung Cell Mol Physiol 2004 287: L428 L437.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Jia, H.P.1
Kline, J.N.2
Penisten, A.3
Apicella, M.A.4
Gioannini, T.L.5
Weiss, J.6
-
51
-
-
33846554134
-
Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells
-
Liu P, Jamaluddin M, Li K, Garofalo RP, Casola A, Brasier AR. Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. J Virol 2007 81: 1401 1411.
-
(2007)
J Virol
, vol.81
, pp. 1401-1411
-
-
Liu, P.1
Jamaluddin, M.2
Li, K.3
Garofalo, R.P.4
Casola, A.5
Brasier, A.R.6
-
52
-
-
33845618496
-
H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM-1 and TLR3 expression
-
Sajjan US, Jia Y, Newcomb DC, Bentley JK, Lukacs NW, LiPuma JJ et al. H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM-1 and TLR3 expression. FASEB J 2006 20: 2121 2123.
-
(2006)
FASEB J
, vol.20
, pp. 2121-2123
-
-
Sajjan, U.S.1
Jia, Y.2
Newcomb, D.C.3
Bentley, J.K.4
Lukacs, N.W.5
Lipuma, J.J.6
-
53
-
-
49249104376
-
Mold allergen, pen C 13, induce inflammatory cytokines in human bronchial epithelial cells via activation of protease-activated receptor
-
Chow L, Chiu L, Yu C, Su S Mold allergen, pen C 13, induce inflammatory cytokines in human bronchial epithelial cells via activation of protease-activated receptor. J Allergy Clin Immunol 2006 117 (2, Suppl. 1 S254.
-
(2006)
J Allergy Clin Immunol
, vol.117
, Issue.2 SUPPL. 1
-
-
Chow, L.1
Chiu, L.2
Yu, C.3
Su, S.4
-
54
-
-
0025784847
-
CDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization
-
Rasmussen UB, Vouret-Craviari V, Jallat S, Schlesinger Y, Pages G, Pavirani A et al. cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization. FEBS Lett 1991 288: 123 128.
-
(1991)
FEBS Lett
, vol.288
, pp. 123-128
-
-
Rasmussen, U.B.1
Vouret-Craviari, V.2
Jallat, S.3
Schlesinger, Y.4
Pages, G.5
Pavirani, A.6
-
55
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991 64: 1057 1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
56
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
-
Nystedt S, Emilsson K, Larsson AK, Strombeck B, Sundelin J. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur J Biochem 1995 232: 84 89.
-
(1995)
Eur J Biochem
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
57
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C et al. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 1997 386: 502 506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.J.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
-
58
-
-
0032510949
-
The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets
-
Schmidt VA, Nierman WC, Maglott DR, Cupit LD, Moskowitz KA, Wainer JA et al. The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets. J Biol Chem 1998 273: 15061 15068.
-
(1998)
J Biol Chem
, vol.273
, pp. 15061-15068
-
-
Schmidt, V.A.1
Nierman, W.C.2
Maglott, D.R.3
Cupit, L.D.4
Moskowitz, K.A.5
Wainer, J.A.6
-
59
-
-
0028814818
-
Constitutive expression and modulation of the functional thrombin receptor in the human kidney
-
Xu Y, Zacharias U, Peraldi MN, He CJ, Lu C, Sraer JD et al. Constitutive expression and modulation of the functional thrombin receptor in the human kidney. Am J Pathol 1995 146: 101 110.
-
(1995)
Am J Pathol
, vol.146
, pp. 101-110
-
-
Xu, Y.1
Zacharias, U.2
Peraldi, M.N.3
He, C.J.4
Lu, C.5
Sraer, J.D.6
-
60
-
-
0027258993
-
Chromosomal assignment of the human thrombin receptor gene: Localization to region q13 of chromosome 5
-
Bahou WF, Nierman WC, Durkin AS, Potter CL, Demetrick DJ. Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5. Blood 1993 82: 1532 1537.
-
(1993)
Blood
, vol.82
, pp. 1532-1537
-
-
Bahou, W.F.1
Nierman, W.C.2
Durkin, A.S.3
Potter, C.L.4
Demetrick, D.J.5
-
61
-
-
0030946582
-
The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13
-
Schmidt VA, Nierman WC, Feldblyum TV, Maglott DR, Bahou WF. The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13. Br J Haematol 1997 97: 523 529.
-
(1997)
Br J Haematol
, vol.97
, pp. 523-529
-
-
Schmidt, V.A.1
Nierman, W.C.2
Feldblyum, T.V.3
Maglott, D.R.4
Bahou, W.F.5
-
62
-
-
0032483456
-
Gene and locus structure and chromosomal localization of the protease-activated receptor gene family
-
Kahn ML, Hammes SR, Botka C, Coughlin SR. Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. J Biol Chem 1998 273: 23290 23296.
-
(1998)
J Biol Chem
, vol.273
, pp. 23290-23296
-
-
Kahn, M.L.1
Hammes, S.R.2
Botka, C.3
Coughlin, S.R.4
-
63
-
-
7944224566
-
The role of protease activation of inflammation in allergic respiratory diseases
-
Reed CE, Kita H. The role of protease activation of inflammation in allergic respiratory diseases. J Allergy Clin Immunol 2004 114: 997 1008.
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 997-1008
-
-
Reed, C.E.1
Kita, H.2
-
64
-
-
0026072517
-
Domains specifying thrombin-receptor interaction
-
Vu TK, Wheaton VI, Hung DT, Charo I, Coughlin SR. Domains specifying thrombin-receptor interaction. Nature 1991 353: 674 677.
-
(1991)
Nature
, vol.353
, pp. 674-677
-
-
Vu, T.K.1
Wheaton, V.I.2
Hung, D.T.3
Charo, I.4
Coughlin, S.R.5
-
65
-
-
0028797819
-
Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system
-
Bouton MC, Jandrot-Perrus M, Moog S, Cazenave JP, Guillin MC, Lanza F. Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system. Biochem J 1995 305: 635 641.
-
(1995)
Biochem J
, vol.305
, pp. 635-641
-
-
Bouton, M.C.1
Jandrot-Perrus, M.2
Moog, S.3
Cazenave, J.P.4
Guillin, M.C.5
Lanza, F.6
-
66
-
-
0034624973
-
Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
-
Camerer E, Huang W, Coughlin SR. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci USA 2000 97: 5255 5260.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5255-5260
-
-
Camerer, E.1
Huang, W.2
Coughlin, S.R.3
-
67
-
-
0034611727
-
PAR3 is a cofactor for PAR4 activation by thrombin
-
Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, Coughlin SR. PAR3 is a cofactor for PAR4 activation by thrombin. Nature 2000 404: 609 613.
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
Zheng, Y.W.2
Sulciner, D.J.3
Weiss, E.J.4
Ludeman, M.J.5
Coughlin, S.R.6
-
68
-
-
0034745133
-
Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets
-
Cumashi A, Ansuini H, Celli N, De Blasi A, O'Brien PJ, Brass LF et al. Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets. Thromb Haemost 2001 85: 533 538.
-
(2001)
Thromb Haemost
, vol.85
, pp. 533-538
-
-
Cumashi, A.1
Ansuini, H.2
Celli, N.3
De Blasi, A.4
O'Brien, P.J.5
Brass, L.F.6
-
69
-
-
0034748449
-
Glycosylation and the activation of proteinase-activated receptor 2 (PAR(2)) by human mast cell tryptase
-
Compton SJ, Renaux B, Wijesuriya SJ, Hollenberg MD. Glycosylation and the activation of proteinase-activated receptor 2 (PAR(2)) by human mast cell tryptase. Br J Pharmacol 2001 134: 705 718.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 705-718
-
-
Compton, S.J.1
Renaux, B.2
Wijesuriya, S.J.3
Hollenberg, M.D.4
-
70
-
-
0029018204
-
Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G
-
Molino M, Blanchard N, Belmonte E, Tarver AP, Abrams C, Hoxie JA et al. Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G. J Biol Chem 1995 270: 11168 11175.
-
(1995)
J Biol Chem
, vol.270
, pp. 11168-11175
-
-
Molino, M.1
Blanchard, N.2
Belmonte, E.3
Tarver, A.P.4
Abrams, C.5
Hoxie, J.A.6
-
71
-
-
0031850771
-
Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts
-
Schechter NM, Brass LF, Lavker RM, Jensen PJ. Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts. J Cell Physiol 1998 176: 365 373.
-
(1998)
J Cell Physiol
, vol.176
, pp. 365-373
-
-
Schechter, N.M.1
Brass, L.F.2
Lavker, R.M.3
Jensen, P.J.4
-
72
-
-
0031890089
-
Dual endothelium-dependent vascular activities of proteinase-activated receptor-2-activating peptides: Evidence for receptor heterogeneity
-
Roy SS, Saifeddine M, Loutzenhiser R, Triggle CR, Hollenberg MD. Dual endothelium-dependent vascular activities of proteinase-activated receptor-2-activating peptides: evidence for receptor heterogeneity. Br J Pharmacol 1998 123: 1434 1440.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 1434-1440
-
-
Roy, S.S.1
Saifeddine, M.2
Loutzenhiser, R.3
Triggle, C.R.4
Hollenberg, M.D.5
-
73
-
-
0036895877
-
Proteinase-activated receptor-2 (PAR2): Vascular effects of a PAR2-derived activating peptide via a receptor different than PAR2
-
McGuire JJ, Dai J, Andrade-Gordon P, Triggle CR, Hollenberg MD. Proteinase-activated receptor-2 (PAR2): vascular effects of a PAR2-derived activating peptide via a receptor different than PAR2. J Pharmacol Exp Ther 2002 303: 985 992.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 985-992
-
-
McGuire, J.J.1
Dai, J.2
Andrade-Gordon, P.3
Triggle, C.R.4
Hollenberg, M.D.5
-
74
-
-
0036078701
-
Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2
-
Stenton GR, Nohara O, Dery RE, Vliagoftis H, Gilchrist M, Johri A et al. Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2. J Pharmacol Exp Ther 2002 302: 466 474.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 466-474
-
-
Stenton, G.R.1
Nohara, O.2
Dery, R.E.3
Vliagoftis, H.4
Gilchrist, M.5
Johri, A.6
-
75
-
-
0346788901
-
Protease-activated receptor 2: Activation, signalling and function
-
Cottrell GS, Amadesi S, Schmidlin F, Bunnett N. Protease-activated receptor 2: activation, signalling and function. Biochem Soc Trans 2003 31: 1191 1197.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1191-1197
-
-
Cottrell, G.S.1
Amadesi, S.2
Schmidlin, F.3
Bunnett, N.4
-
76
-
-
0028923464
-
The thrombin receptor in human platelets is coupled to a GTP binding protein of the G alpha q family
-
Benka ML, Lee M, Wang GR, Buckman S, Burlacu A, Cole L et al. The thrombin receptor in human platelets is coupled to a GTP binding protein of the G alpha q family. FEBS Lett 1995 363: 49 52.
-
(1995)
FEBS Lett
, vol.363
, pp. 49-52
-
-
Benka, M.L.1
Lee, M.2
Wang, G.R.3
Buckman, S.4
Burlacu, A.5
Cole, L.6
-
77
-
-
0030756508
-
Defective platelet activation in G alpha(q)-deficient mice
-
Offermanns S, Toombs CF, Hu YH, Simon MI. Defective platelet activation in G alpha(q)-deficient mice. Nature 1997 389: 183 186.
-
(1997)
Nature
, vol.389
, pp. 183-186
-
-
Offermanns, S.1
Toombs, C.F.2
Hu, Y.H.3
Simon, M.I.4
-
78
-
-
34547107639
-
Beta-Arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
-
Zoudilova M, Kumar P, Ge L, Wang P, Bokoch GM, DeFea KA. Beta-Arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J Biol Chem 2007 282: 20634 20646.
-
(2007)
J Biol Chem
, vol.282
, pp. 20634-20646
-
-
Zoudilova, M.1
Kumar, P.2
Ge, L.3
Wang, P.4
Bokoch, G.M.5
Defea, K.A.6
-
79
-
-
0037136569
-
ADAM-33 surfaces as an asthma gene
-
Shapiro SD, Owen CA. ADAM-33 surfaces as an asthma gene. N Engl J Med 2002 347: 936 938.
-
(2002)
N Engl J Med
, vol.347
, pp. 936-938
-
-
Shapiro, S.D.1
Owen, C.A.2
-
80
-
-
1642313810
-
SPINK5: A gene for atopic dermatitis and asthma
-
Moffatt MF. SPINK5: a gene for atopic dermatitis and asthma. Clin Exp Allergy 2004 34: 325 327.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 325-327
-
-
Moffatt, M.F.1
-
81
-
-
0036533649
-
Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
-
Asokananthan N, Graham PT, Fink J, Knight DA, Bakker AJ, McWilliam AS et al. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 2002 168: 3577 3585.
-
(2002)
J Immunol
, vol.168
, pp. 3577-3585
-
-
Asokananthan, N.1
Graham, P.T.2
Fink, J.3
Knight, D.A.4
Bakker, A.J.5
McWilliam, A.S.6
-
82
-
-
0037108373
-
House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: The cysteine protease allergen, der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1
-
Asokananthan N, Graham PT, Stewart DJ, Bakker AJ, Eidne KA, Thompson PJ et al. House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1. J Immunol 2002 169: 4572.
-
(2002)
J Immunol
, vol.169
, pp. 4572
-
-
Asokananthan, N.1
Graham, P.T.2
Stewart, D.J.3
Bakker, A.J.4
Eidne, K.A.5
Thompson, P.J.6
-
83
-
-
1142285213
-
German cockroach extract activates protease-activated receptor 2 in human airway epithelial cells
-
Hong JH, Lee SI, Kim KE, Yong TS, Seo JT, Sohn MH et al. German cockroach extract activates protease-activated receptor 2 in human airway epithelial cells. J Allergy Clin Immunol 2004 113: 315 319.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 315-319
-
-
Hong, J.H.1
Lee, S.I.2
Kim, K.E.3
Yong, T.S.4
Seo, J.T.5
Sohn, M.H.6
-
84
-
-
0035575784
-
Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2
-
Miike S, McWilliam AS, Kita H. Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2. J Immunol 2001 167: 6615.
-
(2001)
J Immunol
, vol.167
, pp. 6615
-
-
Miike, S.1
McWilliam, A.S.2
Kita, H.3
-
85
-
-
0346995204
-
Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)-2 and extracellular-signal-regulated kinase
-
Page K, Strunk VS, Hershenson MB. Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)-2 and extracellular-signal-regulated kinase. J Allergy Clin Immunol 2003 112: 1112 1118.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 1112-1118
-
-
Page, K.1
Strunk, V.S.2
Hershenson, M.B.3
-
87
-
-
34648846307
-
Activation of protease-activated receptor-2 reduces airways inflammation in experimental allergic asthma
-
D'Agostino B, Roviezzo F, De Palma R, Terracciano S, De Nardo M, Gallelli L et al. Activation of protease-activated receptor-2 reduces airways inflammation in experimental allergic asthma. Clin Exp Allergy 2007 37: 1436 1443.
-
(2007)
Clin Exp Allergy
, vol.37
, pp. 1436-1443
-
-
D'Agostino, B.1
Roviezzo, F.2
De Palma, R.3
Terracciano, S.4
De Nardo, M.5
Gallelli, L.6
-
88
-
-
0033545627
-
A protective role for protease-activated receptors in the airways
-
Cocks TM, Fong B, Chow JM, Anderson GP, Frauman AG, Goldie RG et al. A protective role for protease-activated receptors in the airways. Nature 1999 398: 156 160.
-
(1999)
Nature
, vol.398
, pp. 156-160
-
-
Cocks, T.M.1
Fong, B.2
Chow, J.M.3
Anderson, G.P.4
Frauman, A.G.5
Goldie, R.G.6
-
89
-
-
0035184146
-
Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
-
Knight D, Lim S, Scaffidi A, Roche N, Chung K, Stewart G et al. Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma. J Allergy Clin Immunol 2001 108: 797 803.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 797-803
-
-
Knight, D.1
Lim, S.2
Scaffidi, A.3
Roche, N.4
Chung, K.5
Stewart, G.6
-
90
-
-
33746713726
-
Gene and protein expression of protease-activated receptor 2 in structural and inflammatory cells in the nasal mucosa in seasonal allergic rhinitis
-
Dinh QT, Cryer A, Trevisani M, Dinh S, Wu S, Cifuentes LB et al. Gene and protein expression of protease-activated receptor 2 in structural and inflammatory cells in the nasal mucosa in seasonal allergic rhinitis. Clin Exp Allergy 2006 36: 1039 1048.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 1039-1048
-
-
Dinh, Q.T.1
Cryer, A.2
Trevisani, M.3
Dinh, S.4
Wu, S.5
Cifuentes, L.B.6
-
91
-
-
34447509746
-
Up-regulation of protease-activated receptor 2 in allergic rhinitis
-
Lee HM, Kim HY, Kang HJ, Woo JS, Chae SW, Lee SH et al. Up-regulation of protease-activated receptor 2 in allergic rhinitis. Ann Otol Rhinol Laryngol 2007 116: 554 558.
-
(2007)
Ann Otol Rhinol Laryngol
, vol.116
, pp. 554-558
-
-
Lee, H.M.1
Kim, H.Y.2
Kang, H.J.3
Woo, J.S.4
Chae, S.W.5
Lee, S.H.6
-
92
-
-
34250754475
-
PAR-2 activation regulates IL-8 and GRO-alpha synthesis by NF-kappaB, but not RANTES, IL-6, eotaxin or TARC expression in nasal epithelium
-
Rudack C, Steinhoff M, Mooren F, Buddenkotte J, Becker K, von Eiff C et al. PAR-2 activation regulates IL-8 and GRO-alpha synthesis by NF-kappaB, but not RANTES, IL-6, eotaxin or TARC expression in nasal epithelium. Clin Exp Allergy 2007 37: 1009 1022.
-
(2007)
Clin Exp Allergy
, vol.37
, pp. 1009-1022
-
-
Rudack, C.1
Steinhoff, M.2
Mooren, F.3
Buddenkotte, J.4
Becker, K.5
Von Eiff, C.6
-
93
-
-
0031037296
-
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma
-
Lopez-Ilasaca M, Crespo P, Pellici PG, Gutkind JS, Wetzker R. Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma. Science 1997 275: 394 397.
-
(1997)
Science
, vol.275
, pp. 394-397
-
-
Lopez-Ilasaca, M.1
Crespo, P.2
Pellici, P.G.3
Gutkind, J.S.4
Wetzker, R.5
-
94
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon F, Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol 2005 26: 447 454.
-
(2005)
Trends Immunol
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
95
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
Ting JP, Kastner DL, Hoffman HM. CATERPILLERs, pyrin and hereditary immunological disorders. Nat Rev Immunol 2006 6: 183 195.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
96
-
-
17644366913
-
NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
-
Inohara N, Chamaillard M, McDonald C, Nunez G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem 2005 74: 355 383.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 355-383
-
-
Inohara, N.1
Chamaillard, M.2
McDonald, C.3
Nunez, G.4
-
98
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Abbott DW, Wilkins A, Asara JM, Cantley LC. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 2004 14: 2217 2227.
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
99
-
-
33645958613
-
TIR, CARD and PYRIN: Three domains for an antimicrobial triad
-
Werts C, Girardin SE, Philpott DJ. TIR, CARD and PYRIN: three domains for an antimicrobial triad. Cell Death Differ 2006 13: 798 815.
-
(2006)
Cell Death Differ
, vol.13
, pp. 798-815
-
-
Werts, C.1
Girardin, S.E.2
Philpott, D.J.3
-
100
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nunez G et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005 307: 731 734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
-
101
-
-
17944380130
-
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri
-
Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR et al. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep 2001 2: 736 742.
-
(2001)
EMBO Rep
, vol.2
, pp. 736-742
-
-
Girardin, S.E.1
Tournebize, R.2
Mavris, M.3
Page, A.L.4
Li, X.5
Stark, G.R.6
-
102
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M et al. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur J Immunol 2005 35: 2459 2470.
-
(2005)
Eur J Immunol
, vol.35
, pp. 2459-2470
-
-
Fritz, J.H.1
Girardin, S.E.2
Fitting, C.3
Werts, C.4
Mengin-Lecreulx, D.5
Caroff, M.6
-
103
-
-
28444471235
-
Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
-
Tada H, Aiba S, Shibata KI, Ohteki T, Takada H. Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect Immun 2005 73: 7967 7976.
-
(2005)
Infect Immun
, vol.73
, pp. 7967-7976
-
-
Tada, H.1
Aiba, S.2
Shibata, K.I.3
Ohteki, T.4
Takada, H.5
-
104
-
-
27444433978
-
NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease
-
Watanabe T, Kitani A, Strober W. NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease. Gut 2005 54: 1515 1518.
-
(2005)
Gut
, vol.54
, pp. 1515-1518
-
-
Watanabe, T.1
Kitani, A.2
Strober, W.3
-
106
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F, Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 2004 117: 561 574.
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
107
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol 2006 7: 318 325.
-
(2006)
Nat Immunol
, vol.7
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
Vance, R.E.6
-
108
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan S, Weiss DS, Dixit VM, Monack DM. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med 2005 202: 1043 1049.
-
(2005)
J Exp Med
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
109
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 2004 430: 213 218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
110
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006 440: 228 232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
111
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002 10: 417 426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
112
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006 440: 233 236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
-
113
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006 440: 237 241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
114
-
-
0035897904
-
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
-
Hampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001 357: 925 928.
-
(2001)
Lancet
, vol.357
, pp. 925-928
-
-
Hampe, J.1
Cuthbert, A.2
Croucher, P.J.3
Mirza, M.M.4
Mascheretti, S.5
Fisher, S.6
-
115
-
-
34247239745
-
Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines
-
Uehara A, Fujimoto Y, Fukase K, Takada H. Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines. Mol Immunol 2007 44: 3100 3111.
-
(2007)
Mol Immunol
, vol.44
, pp. 3100-3111
-
-
Uehara, A.1
Fujimoto, Y.2
Fukase, K.3
Takada, H.4
-
116
-
-
3142581432
-
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein I[kappa]B[zeta]
-
Yamamoto M, Yamazaki S, Uematsu S, Sato S, Hemmi H, Hoshino K et al. Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein I[kappa]B[zeta]. Nature 2004 430: 218 222.
-
(2004)
Nature
, vol.430
, pp. 218-222
-
-
Yamamoto, M.1
Yamazaki, S.2
Uematsu, S.3
Sato, S.4
Hemmi, H.5
Hoshino, K.6
-
117
-
-
14844293877
-
Positive and negative regulation of nuclear factor-{kappa}B-mediated transcription by I{kappa}B-{zeta}, an inducible nuclear protein
-
Motoyama M, Yamazaki S, Eto-Kimura A, Takeshige K, Muta T. Positive and negative regulation of nuclear factor-{kappa}B-mediated transcription by I{kappa}B-{zeta}, an inducible nuclear protein. J Biol Chem 2005 280: 7444 7451.
-
(2005)
J Biol Chem
, vol.280
, pp. 7444-7451
-
-
Motoyama, M.1
Yamazaki, S.2
Eto-Kimura, A.3
Takeshige, K.4
Muta, T.5
-
118
-
-
0347065364
-
Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but Not TLR3 requires the p65 subunit of NF-{kappa}
-
Wietek C, Miggin SM, Jefferies CA, O'Neill LAJ. Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but Not TLR3 requires the p65 subunit of NF-{kappa}. J Biol Chem 2003 278: 50923 50931.
-
(2003)
J Biol Chem
, vol.278
, pp. 50923-50931
-
-
Wietek, C.1
Miggin, S.M.2
Jefferies, C.A.3
O'Neill, L.A.J.4
-
119
-
-
0036241055
-
Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
-
Hu CD, Chinenov Y, Kerppola TK. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol Cell 2002 9: 789 798.
-
(2002)
Mol Cell
, vol.9
, pp. 789-798
-
-
Hu, C.D.1
Chinenov, Y.2
Kerppola, T.K.3
|