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Volumn 40, Issue 12, 2004, Pages 861-868

TIR domain-containing adaptors define the specificity of TLR signaling

Author keywords

MyD88; MyD88 independent pathway; TIRAP Mal; TLRs; TRIF

Indexed keywords

BETA INTERFERON; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 1;

EID: 0346157331     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2003.10.006     Document Type: Article
Times cited : (311)

References (49)
  • 2
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L., Holt A.C., Medzhitov R., Flavell R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 413(6857):2001;732-738.
    • (2001) Nature , vol.413 , Issue.6857 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 3
    • 0038731144 scopus 로고    scopus 로고
    • Linking Toll-like receptors to IFN-alpha/beta expression
    • Barton G.M., Medzhitov R. Linking Toll-like receptors to IFN-alpha/beta expression. Nat. Immunol. 4(5):2003;432-433.
    • (2003) Nat. Immunol. , vol.4 , Issue.5 , pp. 432-433
    • Barton, G.M.1    Medzhitov, R.2
  • 4
    • 0042591216 scopus 로고    scopus 로고
    • TIRP: A novel TIR domain-containing adapter protein involved in Toll/interleukin-1 receptor signaling
    • Bin L.H., Xu L.G., Shu H.B. TIRP: a novel TIR domain-containing adapter protein involved in Toll/interleukin-1 receptor signaling. J. Biol. Chem. 278(27):2003;24526-24532.
    • (2003) J. Biol. Chem. , vol.278 , Issue.27 , pp. 24526-24532
    • Bin, L.H.1    Xu, L.G.2    Shu, H.B.3
  • 10
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S., Karin M. Missing pieces in the NF-kappaB puzzle. Cell. 109(Suppl.):2002;S81-S96.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 11
    • 0034698739 scopus 로고    scopus 로고
    • Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6
    • Hacker H., Vabulas R.M., Takeuchi O., Hoshino K., Akira S., Wagner H. Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. J. Exp. Med. 192(4):2000;595-600.
    • (2000) J. Exp. Med. , vol.192 , Issue.4 , pp. 595-600
    • Hacker, H.1    Vabulas, R.M.2    Takeuchi, O.3    Hoshino, K.4    Akira, S.5    Wagner, H.6
  • 14
    • 0037443644 scopus 로고    scopus 로고
    • The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
    • Hemmi H., Kaisho T., Takeda K., Akira S. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J. Immunol. 170(6):2003;3059-3064.
    • (2003) J. Immunol. , vol.170 , Issue.6 , pp. 3059-3064
    • Hemmi, H.1    Kaisho, T.2    Takeda, K.3    Akira, S.4
  • 16
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • Horng T., Barton G.M., Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2(9):2001;835-841.
    • (2001) Nat. Immunol. , vol.2 , Issue.9 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 17
    • 0037153130 scopus 로고    scopus 로고
    • The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    • Horng T., Barton G.M., Flavell R.A., Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature. 420(6913):2002;329-333.
    • (2002) Nature , vol.420 , Issue.6913 , pp. 329-333
    • Horng, T.1    Barton, G.M.2    Flavell, R.A.3    Medzhitov, R.4
  • 18
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., Takeda K., Akira S. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162(7):1999;3749-3752.
    • (1999) J. Immunol. , vol.162 , Issue.7 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6    Takeda, K.7    Akira, S.8
  • 19
    • 0035399769 scopus 로고    scopus 로고
    • Toll receptors in innate immunity
    • Imler J.L., Hoffmann J.A. Toll receptors in innate immunity. Trends Cell Biol. 11(7):2001;304-311.
    • (2001) Trends Cell Biol. , vol.11 , Issue.7 , pp. 304-311
    • Imler, J.L.1    Hoffmann, J.A.2
  • 20
    • 0037322295 scopus 로고    scopus 로고
    • Toll signaling: The TIReless quest for specificity
    • Imler J.L., Hoffmann J.A. Toll signaling: the TIReless quest for specificity. Nat. Immunol. 4(2):2003;105-106.
    • (2003) Nat. Immunol. , vol.4 , Issue.2 , pp. 105-106
    • Imler, J.L.1    Hoffmann, J.A.2
  • 22
    • 0037292275 scopus 로고    scopus 로고
    • Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
    • Janssens S., Beyaert R. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol. Cell. 11(2):2003;293-302.
    • (2003) Mol. Cell. , vol.11 , Issue.2 , pp. 293-302
    • Janssens, S.1    Beyaert, R.2
  • 23
    • 0035339861 scopus 로고    scopus 로고
    • Endotoxin-induced maturation of MyD88-deficient dendritic cells
    • Kaisho T., Takeuchi O., Kawai T., Hoshino K., Akira S. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166(9):2001;5688- 5694.
    • (2001) J. Immunol. , vol.166 , Issue.9 , pp. 5688-5694
    • Kaisho, T.1    Takeuchi, O.2    Kawai, T.3    Hoshino, K.4    Akira, S.5
  • 25
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai T., Adachi O., Ogawa T., Takeda K., Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity. 11(1):1999;115-122.
    • (1999) Immunity , vol.11 , Issue.1 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 26
    • 0035889228 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
    • Kawai T., Takeuchi O., Fujita T., Inoue J., Muhlradt P.F., Sato S., Hoshino K., Akira S. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167(10):2001;5887-5894.
    • (2001) J. Immunol. , vol.167 , Issue.10 , pp. 5887-5894
    • Kawai, T.1    Takeuchi, O.2    Fujita, T.3    Inoue, J.4    Muhlradt, P.F.5    Sato, S.6    Hoshino, K.7    Akira, S.8
  • 27
    • 0036076593 scopus 로고    scopus 로고
    • Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling
    • Matsumoto M., Kikkawa S., Kohase M., Miyake K., Seya T. Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. Biochem. Biophys. Res. Commun. 293(5):2002;1364-1369.
    • (2002) Biochem. Biophys. Res. Commun. , vol.293 , Issue.5 , pp. 1364-1369
    • Matsumoto, M.1    Kikkawa, S.2    Kohase, M.3    Miyake, K.4    Seya, T.5
  • 28
    • 0036449063 scopus 로고    scopus 로고
    • Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily
    • O'Neill L.A. Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily. Curr. Top. Microbiol. Immunol. 270:2002a;47-61.
    • (2002) Curr. Top. Microbiol. Immunol. , vol.270 , pp. 47-61
    • O'Neill, L.A.1
  • 29
    • 0036864723 scopus 로고    scopus 로고
    • Wanted: A molecular basis for specificity in toll-like receptor signal transduction
    • O'Neill L.A. Wanted: a molecular basis for specificity in toll-like receptor signal transduction. Mol. Cell. 10(5):2002b;969-971.
    • (2002) Mol. Cell. , vol.10 , Issue.5 , pp. 969-971
    • O'Neill, L.A.1
  • 31
    • 0037320451 scopus 로고    scopus 로고
    • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
    • Oshiumi H., Matsumoto M., Funami K., Akazawa T., Seya T. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat. Immunol. 4(2):2003;161-167.
    • (2003) Nat. Immunol. , vol.4 , Issue.2 , pp. 161-167
    • Oshiumi, H.1    Matsumoto, M.2    Funami, K.3    Akazawa, T.4    Seya, T.5
  • 32
    • 0033623848 scopus 로고    scopus 로고
    • IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex
    • Peters R.T., Liao S.M., Maniatis T. IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex. Mol. Cell. 5(3):2000;513-522.
    • (2000) Mol. Cell. , vol.5 , Issue.3 , pp. 513-522
    • Peters, R.T.1    Liao, S.M.2    Maniatis, T.3
  • 34
    • 0033485542 scopus 로고    scopus 로고
    • NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
    • Pomerantz J.L., Baltimore D. NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. EMBO J. 18(23):1999;6694-6704.
    • (1999) EMBO J. , vol.18 , Issue.23 , pp. 6694-6704
    • Pomerantz, J.L.1    Baltimore, D.2
  • 36
    • 0034699340 scopus 로고    scopus 로고
    • Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88
    • Schnare M., Holt A.C., Takeda K., Akira S., Medzhitov R. Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88. Curr. Biol. 10(18):2000;1139-1142.
    • (2000) Curr. Biol. , vol.10 , Issue.18 , pp. 1139-1142
    • Schnare, M.1    Holt, A.C.2    Takeda, K.3    Akira, S.4    Medzhitov, R.5
  • 37
    • 0035808446 scopus 로고    scopus 로고
    • Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3
    • Servant M.J., ten Oever B., LePage C., Conti L., Gessani S., Julkunen I., Lin R., Hiscott J. Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3. J. Biol. Chem. 276(1):2001;355-363.
    • (2001) J. Biol. Chem. , vol.276 , Issue.1 , pp. 355-363
    • Servant, M.J.1    Ten Oever, B.2    Lepage, C.3    Conti, L.4    Gessani, S.5    Julkunen, I.6    Lin, R.7    Hiscott, J.8
  • 38
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an ikk-related pathway
    • Sharma S., TenOever B.R., Grandvaux N., Zhou G.P., Lin R., Hiscott J. Triggering the interferon antiviral response through an ikk-related pathway. Science. 300(5622):2003;1148-1151.
    • (2003) Science , vol.300 , Issue.5622 , pp. 1148-1151
    • Sharma, S.1    Tenoever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscott, J.6
  • 40
    • 0037165642 scopus 로고    scopus 로고
    • Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide
    • Shinobu N., Iwamura T., Yoneyama M., Yamaguchi K., Suhara W., Fukuhara Y., Amano F., Fujita T. Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide. FEBS Lett. 517(1/3):2002;251-256.
    • (2002) FEBS Lett. , vol.517 , Issue.1-3 , pp. 251-256
    • Shinobu, N.1    Iwamura, T.2    Yoneyama, M.3    Yamaguchi, K.4    Suhara, W.5    Fukuhara, Y.6    Amano, F.7    Fujita, T.8
  • 42
    • 0036775463 scopus 로고    scopus 로고
    • IRAK-4 as the central TIR signaling mediator in innate immunity
    • Suzuki N., Suzuki S., Yeh W.C. IRAK-4 as the central TIR signaling mediator in innate immunity. Trends. Immunol. 23(10):2002b;503.
    • (2002) Trends. Immunol. , vol.23 , Issue.10 , pp. 503
    • Suzuki, N.1    Suzuki, S.2    Yeh, W.C.3
  • 44
    • 0033968625 scopus 로고    scopus 로고
    • Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
    • Takeuchi O., Takeda K., Hoshino K., Adachi O., Ogawa T., Akira S. Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int. Immunol. 12(1):2000;113-117.
    • (2000) Int. Immunol. , vol.12 , Issue.1 , pp. 113-117
    • Takeuchi, O.1    Takeda, K.2    Hoshino, K.3    Adachi, O.4    Ogawa, T.5    Akira, S.6
  • 45
  • 48
    • 0037114185 scopus 로고    scopus 로고
    • Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
    • Yamamoto M., Sato S., Mori K., Hoshino K., Takeuchi O., Takeda K., Akira S. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J. Immunol. 169(12):2002b;6668-6672.
    • (2002) J. Immunol. , vol.169 , Issue.12 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6    Akira, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.