SPINK5: A gene for atopic dermatitis and asthma

Clinical and Experimental Allergy

Volumn 34, Issue 3, 2004, Pages 325-327

  Moffatt, M F ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN;

ASTHMA; ATOPIC DERMATITIS; CLINICAL GENETICS; EDITORIAL; GENE; GENETIC CODE; GENETIC LINKAGE; GENETIC SCREENING; HUMAN; IMMUNE RESPONSE; MOLECULAR CLONING; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SPINK5 GENE;

ASTHMA; CARRIER PROTEINS; DERMATITIS, ATOPIC; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN E; LINKAGE (GENETICS); MUTATION; SKIN; SPLEEN; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 1642313810     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2004.01915.x     Document Type: Editorial

References (30)

1. Williams H, Robertson C, Stewart A et al. Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood. J Allergy Clin Immunol 1999; 103 (Part 1):125-38.
2. Herd R, Tidman M, Prescott R, Hunter J. The cost of atopic eczema. Br J Dermatol 1996; 135:20-3.
3. Kemp A. Atopic eczema: its social and financial costs. J Paediatr Child Health 1999; 35:229-31.
4. Juhlin L, Johansson G, Bennich H, Hogman C, Thyresson N. Immunoglobulin E in dermatoses. Levels in atopic dermatitis and urticaria. Arch Dermatol 1969; 100:12-6.
5. Cox HE, Moffatt MF, Faux JA et al. Association of atopic dermatitis to the beta subunit of the high affinity immunoglobulin E receptor. Br J Dermatol 1998; 138:182-7.
6. Bos J. Immunology of atopic dermatitis. Oxford: Blackwell Science, 2000.
7. Lee YA, Wahn U, Kehrt R et al. A major susceptibility locus for atopic dermatitis maps to chromosome 3q21. Nat Genet 2000; 26:470-3.
8. Cookson WO, Ubhi B, Lawrence R et al. Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet 2001; 27:372-3.
9. Bradley M, Soderhall C, Luthamn H, Wahlgren CF, Kockum I, Nordenskjold M. Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17 and 18 in a Swedish population. Hum Mol Genet 2002; 11:1539-48.
10. Ober C, Moffatt MF. Contributing factors to the pathobiology: the genetics of asthma. In: Wenzel SE, ed. The pathobiology of asthma: implication for therapy. Clinics in chest medicine, 21(2). Philadelphia: WB Saunders, 2000; 245-61.
11. Judge MR, Morgan G, Harper JI. A clinical and immunological study of Netherton's syndrome. Br J Dermatol 1994; 131:615-21.
12. Chavanas S, Bodemer C, Rochat A et al. Mutations in SPINK5 encoding a serine proteinase inhibitor, cause Netherton syndrome. Nat Genet 2000; 25:141-2.
13. Walley AJ, Chavanas S, Moffatt MF et al. Gene polymorphism in Netherton and common atopic disease. Nat Genet 2001; 29:175-8.
14. Kabesch M, Carr D, Weiland SK, von Mutius E. The association between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sample. Clin Exp Allergy 2004; 34:340-5.
15. Magert HJ, Standker L, Kreutzmann P et al. LEKTI, a novel 15-domain type of human serine proteinase inhibitor. J Biol Chem 1999; 274:21499-502.
16. Bitoun E, Micheloni A, Lamant L et al. LETKI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome. Hum Mol Genet 2003; 12:2417-30.
17. Kato A, Fukai K, Oiso N, Hosomi N, Murakami T, Ishii M. Association of SPINK5 gene polymorphisms with atopic dermatitis in the Japanese population. Br J Dermal 2003; 148:665-9.
18. Nichio Y, Noguchi E, Shibasaki M et al. Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japaneses. Genes Immunity 2003; 4:515-7.
19. Magert HJ, Kreutzmann P, Standker L, Walden M, Drogemuller K, Forssmann WG. LEKTI: a multidomain serine proteinase inhibitor with pathophysiological relevance. Int J Biochem Cell Biol 2002; 34:573-6.
20. Mitsudo K, Jayakumar A, Henderson Y et al. Inhibition of serine proteinases plasmin, trypsin, subtilisin A cathepsin G and elastase by LEKTI: a kinetic analysis. Biochemistry 2003; 42:3874-81.
21. Derian CK, Eckardt AT, Andrade-Gordon P. Differential regulation of human keratinocyte growth and differentiation by a novel family of protease-activate receptors. Cell Growth Differ 1997; 8:743-9.
22. Komatsu N, Takata M, Otsuki N et al. Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides. J Invest Dermatol 2002; 188:436-43.
23. Rice KD, Tanak RD, Katz BA, Numerof RP, Moore WR. Inhibitors of trypase for the treatment of mast cell-mediated diseases. Curr Pharm Res 1998; 4:381-96.
24. Schechter NM, Brass LF, Lavker RM, Jensen PJ. Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts. J Cell Physiol 1998; 176:365-73.
25. He S, Gaca MD, Walls AF. A role for tryptase in the activation of human mast cells: modulation of histamine release by tryptase and inhibitors of tryptase. J Pharmacol Exp Ther 1998; 286:289-97.
26. Thomas WT, Smith WA, Hales BJ, Mills KL, O'Brien RM. Characterization and immunobiology of house dust mite allergens. Int Arch Allergy Immunol 2002; 129:1-18.
27. Breuer K, Kappa A, Werfel T. Bacterial infections and atopic dermatitis. Allergy 2001; 56:1437-46.
28. Miedzobrodzki J, Kaszycki P, Bialecka A, Kasprowicz A. Proteolytic activity of Staphylococcus aureus strains isolated from the colonized skin of patients with acute-phase atopic dermatitis. Eur J Clin Microbiol Infect Dis 2002; 21:269-76.
29. Bachert C, Gevaert P, van Cauwenberge P. Staphylococcus aureus enterotoxins: a key in airway disease? Allergy 2002; 57:480-7.
30. Bachert C, Gevaert P, Howards P, Holtappels G, van Cauwenberge P, Johnasson SGO. IgE to Staphylococcus aureus enterotoxins in serum is related to severity of asthma. J Allergy Clin Immunol 2003; 111:1131-2.