Dual endothelium-dependent vascular activities of proteinase-activated receptor-2-activating peptides: evidence for receptor heterogeneity

British Journal of Pharmacology

Volumn 123, Issue 7, 1998, Pages 1434-1440

  Roy, Samir S ^a   Saifeddine, Mahmoud ^a   Loutzenhiser, Rodger ^a   Triggle, Chris R ^a   Hollenberg, Morley D ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Endothelium; Par1; Par2; Protease activated receptor; Pulmonary artery; Thrombin receptor; Trypsin

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); INDOMETACIN; LOSARTAN POTASSIUM; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PEPTIDE; PRAZOSIN; PROADIFEN; PROTEINASE ACTIVATED RECEPTOR 2 ACTIVATING PEPTIDE; TETRODOTOXIN; THROMBIN; THROMBIN RECEPTOR; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; BLOOD VESSEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PULMONARY ARTERY; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; STRUCTURE ACTIVITY RELATION; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PAR-2; RECEPTORS, THROMBIN;

EID: 0031890089     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701726     Document Type: Article

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