JNK: A key modulator of intracellular signaling

Biochemistry (Moscow)

Volumn 69, Issue 8, 2004, Pages 844-854

  Vlahopoulos, S ^a   Zoumpourlis, V C ^a  

^a INSTITUTE OF BIOLOGY   (Greece)

Author keywords

Apoptosis; Cancer; Gene promoter; Inflammation; JNK; Reactive oxygen species (ROS)

Indexed keywords

ADHESION; BIOCHEMISTRY; BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; ENZYMES; GENETIC ENGINEERING; MOLECULAR WEIGHT; SUBSTRATES; TUMORS;

APOPTOSIS; C-JUN N-TERMINAL KINASE (JNK); INFLAMMATION; REACTIVE OXYGEN SPECIES (ROS);

CYTOLOGY;

STRESS ACTIVATED PROTEIN KINASE;

ANIMAL; CELL DIFFERENTIATION; ENZYME SPECIFICITY; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; OXIDATIVE STRESS; SUBSTRATE SPECIFICITY;

EID: 4444287774     PISSN: 00062979     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BIRY.0000040215.02460.45     Document Type: Article

References (165)

1. Kyriakis, J. M., and Avruch, J. (2001) Physiol. Rev., 81, 807-869.
2. Dunn, C., Wiltshire, C., MacLaren, A., and Gillespie, D. A. (2002) Cell Signal., 14, 585-593.
3. Ramet, M., Lanot, R., Zachary, D., and Manfruelli, P. (2002) Dev. Biol., 241, 145-156.
4. Kawasaki, M., Hisamoto, N., Iino, Y., Yamamoto, M., Ninomiya-Tsuji, J., and Matsumoto, K. (1999) EMBO J., 18, 3604-3615.
5. Gallo, K. A., and Johnson, G. L. (2002) Nat. Rev. Mol. Cell. Biol., 3, 663-672.
6. Davis, R. J. (2000) Cell, 103, 239-252.
7. Xie, X., Gu, Y., Fox, T., Coll, J. T., Fleming, M. A., Markland, W., Caron, P. R., Wilson, K. P., and Su, M. S. (1998) Structure, 6, 983-991.
8. Bennett, B. L., Sasaki, D. T., Murray, B. W., O'Leary, E. C., Sakata, S. T., Xu, W., Leisten, J. C., Motiwala, A., Pierce, S., Satoh, Y., Bhagwat, S. S., Manning, A. M., and Anderson, D. W. (2001) Proc. Natl. Acad. Sci. USA, 98, 13681-13686.
9. Li, B., Tournier, C., Davis, R. J., and Flavell, R. A. (1999) EMBO J., 18, 420-432.
10. Li, J., Kartha, S., Iasvovskaia, S., Tan, A., Bhat, R. K., Manaligod, J. M., Page, K., Brasier, A. R., and Hershenson, M. B. (2002) Am. J. Physiol. Lung Cell. Mol. Physiol., 283, L690-699.
11. Wang, Y., Li, C., Wang, X., Zhang, J., and Chang, Z. (2002) Biochem. Biophys. Res. Commun., 296, 742-748.
12. Michiels, C., Minet, E., Michel, G., Mottet, D., Piret, J. P., and Raes, M. (2001) IUBMB Life, 52, 49-53.
13. Gee, K., Lim, W., Ma, W., Nandan, D., Diaz-Mitoma, F., Kozlowski, M., and Kumar, A. (2002) J. Immunol., 169, 5660-5672.
14. Chang, L., and Karin, M. (2001) Nature, 410, 37-40.
15. Cai, Y., Zhang, C., Nawa, T., Aso. T., Tanaka, M., Oshiro, S., Ichijo, H., and Kitajima, S. (2000) Blood, 96, 2140-2148.
16. Reboul, P., Pelletier, J. P., Tardif, G., Benderdour, M., Ranger, P., Bottaro, D. P., and Martel-Pelletier, J. (2001) Arthritis Rheum., 44, 73-84.
17. Shin, M., Yan, C., and Boyd, D. (2002) Biochim. Biophys. Acta, 1589, 311-316.
18. Zhang, X., Bedard, E. L., Potter, R., Zhong, R., Alam, J., Choi, A. M., and Lee, P. J. (2002) Am. J. Physiol. Lung Cell. Mol. Physiol., 283, L815-829.
19. Umenishi, F., and Schrier, R. W. (2003) J. Biol. Chem., 278, 15765-15770.
20. Chen, A., and Davis, B. H. (2000) Mol. Cell. Biol., 20, 2818-2826.
21. Hocevar, B. A., Brown, T. L., and Howe, P. H. (1999) EMBO J., 18, 1345-1356.
22. Schwabe, R. F., Bradham, C. A., Uehara, T., Hatano, E., Bennett, B. L., Schoonhoven, R., and Brenner, D. A. (2003) Hepatology, 37, 824-832.
23. Ellsworth, B. S., White, B. R., Burns, A. T., Cherrington, B. D., Otis, A. M., and Clay, C. M. (2003) Endocrinology, 144, 839-849.
24. Tamanini, A., Rolfini, R., Nicolis, E., Melotti, P., and Cabrini, G. (2003) Virology, 307, 228-242.
25. Ju, J. W., Kim, S. J., Jun, C. D., and Chun, J. S. (2002) IUBMB Life, 54, 293-299.
26. Verrecchia, F., Tacheau, C., Wagner, E. F., and Mauviel, A. (2003) J. Biol. Chem., 278, 1585-1593.
27. Grosch, S., Tegeder, I., Schilling, K., Maier, T. J., Niederberger, E., and Geisslinger, G. (2003) FASEB J., 17, 1316-1318.
28. Zoumpourlis, V., Papassava, P., Linardopoulos, S., Gillespie, D., Balmain, A., and Pintzas, A. (2000) Oncogene. 19, 4011-4021.
29. Buschmann, T., Potapova, O., Bar-Shira, A., Ivanov, V. N., Fuchs, S. Y., Henderson, S., Fried, V. A., Minamoto, T., Alarcon-Vargas, D., Pincus, M. R., Gaarde, W. A., Holbrook, N. J., Shiloh, Y., and Ronai, Z. (2001) Mol. Cell. Biol., 21, 2743-2754.
30. Noguchi, K., Kitanaka, C., Yamana, H., Kokubu, A., Mochizuki, T., and Kuchino, Y. (1999) J. Biol. Chem., 274, 32580-32587.
31. Prendergast, G. C. (1999) Oncogene, 18, 2967-2987.
32. Aplin, A. E., Hogan, B. P., Tomeu, J., and Juliano, R. L. (2002) J. Cell. Set., 115, 2781-2790.
33. Chow, C. W., Rincon, M., Cavanagh, J., Dickens, M., and Davis, R. J. (1997) Science, 278, 1638-1641.
34. Itoh, M., Adachi, M., Yasui, H., Takekawa, M., Tanaka, H., and Imai, K. (2002) Mol. Endocrinol., 16, 2382-2392.
35. Mizukami, Y., Yoshioka, K., Morimoto, S., and Yoshida, K. (1997) J. Biol. Chem., 272, 16657-16662.
36. Deng. X., Xiao, L., Lang, W., Gao, F., Ruvolo, P., and May, W. S., Jr. (2001) J. Biol. Chem., 276, 23681-23668.
37. Kharbanda, S., Saxena, S., Yoshida, K., Pandey, P., Kaneki, M., Wang, Q., Cheng, K., Chen, Y. N., Campbell, A., Sudha, T., Yuan, Z. M., Narula, J., Weichselbaum, R., Nalin, C., and Kufe, D. (2000) J. Biol. Chem., 275, 322-327.
38. Inoshita, S., Takeda, K., Hatai, T., Terada, Y., Sano, M., Hata, J., Umezawa, A., and Ichijo, H. (2002) J. Biol. Chem., 277, 43730-43734.
39. Ito, Y., Mishra, N. C., Yoshida, K., Kharbanda, S., Saxena, S., and Kufe, D. (2001) Cell Death Differ., 8, 794-800.
40. Donovan, N., Becker, E. B., Konishi, Y., and Bonni, A. (2002) J. Biol. Chem., 277, 40944-40949.
41. Whitmarsh, A. J., Cavanagh, J., Tournier, C., Yasuda. J., and Davis, R. J. (1998) Science, 281, 1671-1674.
42. Lee, C. M., Onesime, D., Reddy, C. D., Dhanasekaran, N., and Reddy, E. P. (2002) Proc. Natl. Acad. Sci. USA, 99, 14189-14194.
43. Ito, M., Yoshioka, K., Akechi, M., Yamashita, S., Takamatsu, N., Sugiyama, K., Hibi, M., Nakabeppu, Y., Shiba, T., and Yamamoto, K. I. (1999) Mol. Cell. Biol., 19, 7539-7548.
44. Barr, R. K., and Bogoyevitch, M. A. (2001) Int. J. Biochem. Cell. Biol., 33, 1047-1063.
45. Kuwabara, M., Takahashi, K., and Inanami, O. (2003) J. Radiat. Res. (Tokyo), 44, 203-209.
46. Sheikh, M. S., Antinore, M. J., Huang, Y., and Fornace, A. J., Jr. (1998) Oncogene, 17, 2555-2563.
47. Hung. C. C., Ichimura, T., Stevens, J. L., and Bonventre, J. V. (2003) J. Biol. Chem., 278, 29317-29326.
48. Parola, M., Robino, G., Marra, F., Pinzani, M., Bellomo, G., Leonarduzzi, G., Chiarugi, P., Camandola, S., Poli, G., Waeg, G., Gentilini, P., and Dianzani, M. U. (1998) J. Clin. Invest., 102, 1942-1950.
49. Wang, T., Arifoglu, P., Ronai, Z., and Tew, K. D. (2001) J. Biol. Chem., 276, 20999-21003.
50. Adler. V., Yin, Z., Fuchs, S. Y., Benezra, M., Rosario, L., Tew, K. D., Pincus, M. R., Sardana, M., Henderson, C. J., Wolf, C. R., Davis, R. J., and Ronai, Z. (1999) EMBO J., 18, 1321-1334.
51. Elsby, R., Kitteringham, N. R., Goldring, C. E., Lovatt, C. A., Chamberlain, M., Henderson, C. J., Wolf, C. R., and Park, B. K. (2003) J. Biol. Chem., 278, 22243-22249.
52. Cheng. W. H., Zheng, X., Quimby, F. R., Roneker, C. A., and Lei, X. G. (2003) Biochem. J., 370, 927-934.
53. Ventura, J.-J., Kennedy, N. J., Lamb, J. A., Flavell, R. A., and Davis, R. J. (2003) Mol. Cell. Biol., 23, 2871-2882.
54. Mandal, M., Olson, D. J., Sharma, T., Vadlamudi, R. K., and Kumar, R. (2001) Gastroenterology, 120, 71-78.
55. Salehi, A. H., Xanthoudakis, S., and Barker, P. A. (2002) J. Biol. Chem., 277, 48043-48050.
56. Yang, Y. M., Bost, F., Charbono, W., Dean, N., McKay, R., Rhim, J. S., Depatie, C., and Mercola, D. (2003) Clin. Cancer Res., 9, 391-401.
57. Hashimoto, Y., Tsuji, O., Niikura, T., Yamagishi, Y., Ishizaka, M., Kawasumi, M., Chiba, T., Kanekura, K., Yamada, M., Tsukamoto, E., Kouyama, K., Terashita, K., Aiso, S., Lin, A., and Nishimoto, I. (2003) J. Neurochem., 84, 864-877.
58. Zheng, C., Xiang, J., Hunter, T., and Lin, A. (1999) J. Biol Chem., 274, 28966-28971.
59. Rennefahrt, U. E., Illert, B., Kerkhoff, E., Troppmair, J., and Rapp, U. R. (2002) J. Biol. Chem., 277, 29510-29518.
60. Chen, N.. She, Q. B., Bode, A. M., and Dong, Z. (2002) Cancer Res., 62, 1300-1304.
61. Yang, D. D., Conze, D., Whitmarsh, A. J., Barrett, T., Davis, R. J., Rincon, M., and Flavell, R. A. (1998) Immunity, 9, 575-585.
62. Verrecchia, F., Wagner, E. F., and Mauviel, A. (2002) EMBO Rep., 3, 1069-1074.
63. Matsuzawa, A., Nishitoh, H., Tobiume, K., Takeda, K., and Ichijo, H. (2002) Antioxid. Redox. Signal., 4, 415-425.
64. Potapova, O., Anisimov, S. V., Gorospe, M., Dougherty, R. H., Gaarde, W. A., Boheler, K. R., and Holbrook, N. J. (2002) Cancer Res., 62, 3257-3263.
65. Manning, A. M., and Davis, R. J. (2003) Nat. Rev. Drug Discov., 2, 554-565.
66. Rahman, I. (2003) J. Biochem. Mol. Biol., 36, 95-109.
67. Hadjigogos, K. (2003) Panminerva Med., 45, 7-13.
68. Andreadis, A. A., Hazen, S. L., Comhair, S. A., and Erzurum, S. C. (2003) Free Rad. Biol. Med., 35, 213-225.
69. Lane, N. (2003) J. Theor. Biol., 225, 531-540.
70. Lo, Y. Y., Wong, J. M., and Cruz, T. F. (1996) J. Biol Chem., 271, 15703-15707.
71. Pinkus, R., Weiner, L. M., and Daniel, V. (1996) J. Biol. Chem., 271, 13422-13429.
72. Han, Z., Boyle, D. L., Chang, L., Bennett, B., Karin, M., Yang, L., Manning, A. M., and Firestein, G. S. (2001) J. Clin. Invest., 108, 73-81.
73. Adcock, I. M., and Caramori, G. (2001) Immunol. Cell. Biol., 79, 376-384.
74. Rahman, A., Kefer, J., Bando, M., Niles, W. D., and Malik, A. B. (1998) Am. J. Physiol., 275, L533-544.
75. Zou, Y., Jung, K. J., Kim, J. W., Yu, B. P., and Chung, H. Y. (2003) FASEB J., 18, 320-322.
76. Krunkosky, T. M., Martin, L. D., Fischer, B. M., Voynow, J. A., and Adler, K. B. (2003) Free Rad. Biol. Med., 35, 1158-1167.
77. Shetty, A., and Forbes, A. (2002) Am. J. Pharmacogenomics, 2, 215-221.
78. Iies, K. E., and Forman, H. J. (2002) Immunol. Res., 26, 95-105.
79. Wilmer, W. A., Tan, L. C., Dickerson, J. A., Danne, M., and Rovin, B. H. (1997) J. Biol. Chem., 272, 10877-10881.
80. Iies, K. E., Dickinson, D. A., Watanabe, N., Iwamoto, T., and Forman, H. J. (2002) Free Rad. Biol. Med., 32, 1304-1313.
81. Adamson, G. M., and Billings, R. E. (1992) Arch. Biochem. Biophys., 294, 223-229.
82. Inanami, O., Takahashi, K., Yoshito, A., and Kuwabara, M. (1999) Antioxid. Redox. Signal., 1, 113-121.
83. Lee, L., Irani, K., and Finkel, T. (1998) Mol. Genet. Metab., 64, 19-24.
84. Inanami, O., Ohta, T., Ito, S., and Kuwabara, M. (1999) Antioxid. Redox. Signal., 1, 501-508.
85. Ozaki, M., Deshpande, S. S., Angkeow, P., Suzuki, S., and Irani, K. (2000) J. Biol. Chem., 275, 35377-35383.
86. Meriane, M., Charrasse, S., Comunale, F., and Gauthier-Rouviere, C. (2002) Biol. Cell., 94, 535-543.
87. Abramov, A. Y., Canevari, L., and Duchen, M. R. (2003) J. Neurosci., 23, 5088-5095.
88. Wilson, D. J., Fortner, K. A., Lynch, D. H., Mattingly, R. R., Macara, I. G., Posada, J. A., and Budd, R. C. (1996) Eur. J. Immunol., 26, 989-994.
89. Gordeeva, A. V., Zvyagilskaya, R. A., and Labas, Y. A. (2003) Biochemistry (Moscow), 68, 1077-1080.
90. Lee, K., and Esselman, W. J. (2002) Free Rad. Biol. Med., 33, 1121-1132.
91. Gu, Y., Xu, Y. C., Wu, R. F., Souza, R. F., Nwariaku, F. E., and Terada, L. S. (2002) Exp. Cell. Res., 272, 62-74.
92. Vlahopoulos, S., Boldogh, I., Casola, A., and Brasier, A. R. (1999) Blood, 94, 1878-1889.
93. Zhou, L., Tan, A., Iasvovskaia, S., Li, J., Lin, A., and Hershenson, M. B. (2003) Am. J. Respir. Cell. Mol. Biol., 28, 762-769.
94. Davidson, B., Givant-Horwitz, V., Lazarovici, P., Risberg, B., Nesland, J. M., Trope, C. G., Schaefer, E., and Reich, R. (2003) Clin. Exp. Metastasis, 20, 621-631.
95. Woo, J. H., Lim, J. H., Kim, Y. H., Suh, S. I., Min, D. S., Chang, J. S., Lee, Y. H., Park, J. W., and Kwon, T. K. (2003) Oncogene, 23, 1845-1853.
96. Katsanakis, K. D., Owen, C., and Zoumpourlis, V. (2002) Anticancer Res., 22, 755-759.
97. Otth, C., Mendoza-Naranjo, A., Mujica, L., Zambrano, A., Concha, I. I., and Maccioni, R. B. (2003) Neuroreport, 14, 2403-2409.
98. Merienne, K., Helmlinger, D., Perkin, G. R., Devys, D., and Trottier, Y. (2003) J. Biol. Chem., 278, 16957-16967.
99. Royuela, M., Arenas, M. I., Bethencourt, F. R., Sanchez-Chapado, M., Fraile, B., and Paniagua, R. (2002) Hum. Pathol., 33, 299-306.
100. Collins, L. R., Minden, A., Karin, M., and Brown, J. H. (1996) J. Biol. Chem., 271, 17349-17353.
101. Pruitt, K., Pruitt, W. M., Bilter, G. K., Westwick, J. K., and Der, C. J. (2002) J. Biol. Chem., 217, 31808-31817.
102. Pulverer, B. J., Kyriakis, J. M., Avruch,. J., Nikolakaki, E., and Woodgett, J. R. (1991) Nature, 353, 670-674.
103. Johnson, R., Spiegelman, B., Hanahan, D., and Wisdom, R. (1996) Mol. Cell. Biol., 16, 4504-4511.
104. Behrens, A., Jochum, W., Sibilia, M., and Wagner, E. F. (2000) Oncogene, 19, 2657-2663.
105. Kennedy, N. J., Sluss, H. K., Jones, S. N., Bar-Sagi, D., Flavell, R. A., and Davis, R. J. (2003) Genes Dev., 17, 629-637.
106. Chen, N., Nomura, M., She, Q. B., Ma, W. Y., Bode, A. M., Wang, L., Flavell, R. A., and Dong, Z. (2001) Cancer Res.. 61, 3908-3912.
107. She, Q. B., Chen, N., Bode, A. M., Flavell, R. A., and Dong, Z. (2002) Cancer Res., 62, 1343-1348.
108. Alfonso-De Matte, M. Y., Yang, H., Evans, M. S., Cheng, J. Q., and Kruk, P. A. (2002) Cancer Res., 62, 4575-4578.
109. Pelengaris, S., Rudolph, B., and Littlewood, T. (2000) Curr. Opin. Genet. Dev., 10, 100-105.
110. Tan, Y., Demeter, M. R., Ruan, H., and Comb. M. J. (2000) J. Biol. Chem., 275, 25865-25869.
111. Crossthwaite, A. J., Hasan, S., and Williams, R. J. (2002) J. Neurochem., 80, 24-35.
112. Sakon, S., Xue, X., Takekawa, M., Sasazuki, T., Okazaki, T., Kojima, Y., Piao, J. H., Yagita, H., Okumura, K., Doi, T., and Nakano, H. (2003) EMBO J., 22, 3898-3909.
113. Deng, Y., Ren, X., Yang, L., Lin, Y., and Wu, X. (2003) Cell, 115, 61-70.
114. Theodosiou, A., and Ashworth, A. (2002) Oncogens, 21, 2387-2397.
115. Palacios, C., Collins, M. K., and Perkins, G. R. (2001) Curr. Biol., 11, 1439-1443.
116. Meriin, A. B., Yaglom, J. A., Gabai, V. L., Zon, L., Ganiatsas, S., Mosser, D. D., Zon, L., and Sherman, M. Y. (1999) Mol. Cell. Biol., 19, 2547-2555.
117. Volloch, V., Gabai, V. L., Rits, S.. Force, T., and Sherman, M. Y. (2000) Cell Stress Chapemnes, 5, 139-147.
118. Park, H. S., Lee, J. S., Huh, S. H., Seo, J. S., and Choi, E. J. (2001) EMBO J., 20, 446-456.
119. Yaglom, J. A., Ekhterae, D., Gabai, V. L., and Sherman, M. Y. (2003) J. Biol. Chem., 278, 50483-50496.
120. Urano, F., Wang, X., Bertolotti, A., Zhang, Y., Chung, P., Harding, H. P., and Ron, D. (2000) Science, 287, 664-666.
121. Chang, H. Y., Nishitoh, H., Yang, X., Ichijo, H., and Baltimore, D. (1998) Science, 281, 1860-1863.
122. Chen, L. Y., and Chen, J. D. (2003) Mol. Cell. Biol., 23, 7108-7121.
123. Michaelson, J. S., and Leder, P. (2003) J. Cell. Sci., 116, 345-352.
124. Kim, Y. Y., Park, B. J., Seo, G. J., Lim, J. Y., Lee, S. M., Kimm, K. C., Park, C., Kim, J., and Park, S. I. (2003) Biochem. Biophys. Res. Commun., 312, 426-433.
125. Chatterjee, M., and Wu, S. (2001) Mol. Cell. Biochem., 219, 21-27.
126. Zhan, Q., Jin, S., Ng, B., Plisket, J., Shangary, S., Rathi, A., Brown, K. D., and Baskaran, R. (2002) Oncogene, 21, 5335-5345.
127. Sordet, O., Khan, Q. A., Kohn, K. W., and Pommier, Y. (2003) Curr. Med. Chem. Anti-cancer Agents, 3, 271-290.
128. Kharbanda, S., Yuan, Z. M., Weichselbaum, R., and Kufe, D. (1998) Oncogene, 17, 3309-3318.
129. Lee, S. A., Dritschilo, A., and Jung, M. (1998) J. Biol. Chem., 273, 32889-32894.
130. Zhang, Y., Ma, W. Y., Kaji, A., Bode, A. M., and Dong, Z. (2002) J. Biol. Chem., 277, 3124-3131.
131. Aoki, H., Kang, P. M., Hampe, J., Yoshimura, K., Noma, T., Matsuzaki, M., and Izumo, S. (2002) J. Biol. Chem., 277, 10244-10250.
132. Watanabe, N., Iwamoto, T., Dickinson, D. A., Iles, K. E., and Forman, H. J. (2002) Arch. Biochem. Biophys., 405, 231-240.
133. Orr, W. C., and Sohal, R. S. (1994) Science, 263, 1128-1130.
134. Wang, M. C., Bohmann, D., and Jasper, H. (2003) Dev. Cell., 5, 811-816.
135. Yoon. S. O., Yun, C. H., and Chung, A. S. (2002) Mech. Ageing Dev., 123, 1597-1604.
136. Krysan, K., and Lou, M. F. (2002) Invest. Ophthalmol. Vis. Sci., 43, 1876-1883.
137. Shen, Y. H., Godlewski, J., Zhu. J., Sathyanarayana, P., Leaner, V., Birrer, M. J., Rana, A., and Tzivion, G. (2003) J. Biol. Chem., 278, 26715-26721.
138. Yu, C., Rahmani, M., Almenara, J., Sausville, E. A., Dent, P., and Grant, S. (2003) Oncogene, 23, 1364-1376.
139. Yu, C., Subler, M., Rahmani, M., Reese, E., Krystal, G., Conrad, D., Dent, P., and Gram, S. (2003) Cancer Biol. Ther., 2, 544-551.
140. Irani, K., Xia, Y., Zweier, J. L., Sollott, S. J., Der, C. J., Fearon, E. R., Sundaresan, M., Finkel, T., and Goldschmidt-Clermont, P. J. (1997) Science, 275, 1649-1652.
141. Burdon, R. H. (1995) Free Rad. Biol. Med., 18, 775-794.
142. Stone, J. R., and Collins, T. (2002) Endothelium, 9, 231-238.
143. Kwon, S. H., Pimentel, D. R., Remondino, A., Sawyer, D. B., and Colucci, W. S. (2003) J. Mol. Cell. Cardiol., 35, 615-621.
144. Cheng, W. H., Zheng, X., Quimby, F. R., Roneker, C. A., and Lei, X. G. (2003) Biochem. J., 370, 927-934.
145. Pollycove, M., and Feinendegen, L. E. (2003) Hum. Exp. Toxicol., 22, 290-306.
146. Van Campen, L. E., Murphy, W. J., Franks, J. R., Mathias, P. I., and Toraason, M. A. (2002) Hear Res., 164, 29-38.
147. Boldogh, I., Roy, G., Lee, M. S., Bacsi, A., Hazra, T. K., Bhakat, K. K., Das, G. C., and Mitra, S. (2003) Toxicology, 193, 137-152.
148. Vivo, C., Liu, W., and Broaddus, V. C. (2003) J. Biol. Chem., 278, 25461-25467.
149. Tang, G., Minemoto, Y., Dibling, B., Purcell, N. H., Li, Z., Karin, M., and Lin, A. (2001) Nature, 414, 313-317.
150. Reuther-Madrid, J. Y., Kashatus, D., Chen, S., Li, X., Westwick, J., Davis, R. J., Earp, H. S., Wang, C. Y., and Baldwin, A. S., Jr. (2002) Mol. Cell. Biol., 22, 8175-8183.
151. Lin, A. (2003) Bioessays, 25, 17-24.
152. Davies, K. J. (1999) IUBMB Life, 48, 41-47.
153. Figueroa-Masot, X. A., Hetman, M., Higgins, M. J., Kokot, N., and Xia, Z. (2001) J. Neurosci., 21, 4657-4667.
154. Shaulian, E., Schreiber, M., Piu, F., Beeche, M., Wagner, E. F., and Karin, M. (2000) Cell, 103, 897-907.
155. Mingo-Sion, A. M., Marietta, P. M., Koller, E., Wolf, D. M., and van den Berg, C. L. (2004) Oncogene, 23, 596-604.
156. Yoshida, S., Fukino, K., Harada, H., Nagai, H., Imoto, I., Inazawa, J., Takahashi, H., Teramoto, A., and Emi, M. (2001) J. Hum. Genet., 46, 182-187.
157. Nishitai, G., Shimizu, N., Negishi, T., Kishimoto, H., Nakagawa, K., Kitagawa, D., Watanabe, T., Momose, H., Ohata, S., Tanemura, S., Asaka, S., Kubota, J., Saito, R., Yoshida, H., Mak, T. W., Wada, T., Penninger, J. M., Azuma, N., Nishina, H., and Katada, T. (2004) J. Biol. Chem., 279, 1621-1626.
158. Habas, R., Dawid, I. B., and He, X. (2003) Genes Dev'., 17, 295-309.
159. Lisovsky, M., Itoh, K., and Sokol, S. Y. (2002) Curr. Biol., 12, 53-58.
160. Dietrich, N., Thastrup, J., Holmberg, C., Gyrd-Hansen, M., Fehrenbacher, N., Lademann, U., Lerdrup, M., Herdegen, T., Jaattela, M., and Kallunki, T. (2003) Cell Death Differ., 11, 301-313.
161. Kuan, C. Y., Yang, D. D., Roy, S. D. R., Davis, R. J., Rakic, P., and Flavell, R. A. (1999) Neuron, 22, 667-676.
162. Sabapathy, K., Jochum, W., Hochedlinger, K., Chang, L., Karin, M., and Wagner, E. F. (1999) Mech. Dev., 89, 115-124.
163. Paris, M., Ensoli, B., Stahl, N., Yancopoulos, G., Nguyen, A., Wang, S., and Nel, A. E. (1996) AIDS, 10, 369-378.
164. Pessah, M., Prunier, C., Marais, J., Ferrand, N., Mazars, A., Lallemand, F., Gauthier, J. M., and Atfi, A. (2001) Proc. Natl. Acad. Sci. USA, 98, 6198-6203.
165. Sepulveda, J. L., Vlahopoulos, S., Iyer, D., Belaguli, N., and Schwartz, R. J. (2002) J. Biol. Chem., 277, 25775-25782.