AP-1 activation through endogenous H2O2 generation by alveolar macrophages

Free Radical Biology and Medicine

Volumn 32, Issue 12, 2002, Pages 1304-1313

  Iles, Karen E ^a   Dickinson, Dale A ^a   Watanabe, Nobuo ^a   Iwamoto, Takeo ^b   Forman, Henry Jay ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

Activator protein 1 (AP 1); ERK; Fos; Free radicals; JNK; Jun; Mitogen activated protein kinases (MAPK); Respiratory burst; Signaling

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADENOSINE DIPHOSPHATE; CATALASE; COMPLEMENT COMPONENT C5A; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; ENZYME INHIBITOR; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN KINASE (CALCIUM,CALMODULIN); REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RESPIRATORY BURST; ANIMAL; CELL CULTURE; CELL NUCLEUS; DRUG ANTAGONISM; DRUG EFFECT; GEL MOBILITY SHIFT ASSAY; METABOLISM; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADENOSINE DIPHOSPHATE; ANIMAL; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL NUCLEUS; CELLS, CULTURED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME INHIBITORS; FLAVONES; HYDROGEN PEROXIDE; MACROPHAGES, ALVEOLAR; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST; SIGNAL TRANSDUCTION; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTOR AP-1; ANIMALS; FLAVONOIDS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4;

EID: 0037096197     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00840-7     Document Type: Article

References (38)

1. 2 production during the respiratory burst in alveolar macrophages
2. The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes
3. Antioxidants and AP-1 activation: A brief overview
4. Modulation of the composition of AP-1 complex and its impact on transcriptional activity
5. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
6. Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
7. Escape from redox regulation enhances the transforming activity of Fos
8. Effects of sodium and proton pump activity on respiratory burst and pH regulation of rat alveolar macrophages
9. Modulation of the alveolar macrophage respiratory burst by hydroperoxides
10. Activation of several MAP kinases upon stimulation of rat alveolar macrophages: Role of the NADPH oxidase
11. ADP stimulates the respiratory burst without activation of ERK and AKT in rat alveolar macrophages
12. From growth factor dependence to growth factor responsiveness: The genesis of an alveolar macrophage cell line
13. Cell-permeable peptide inhibitors of JNK: Novel blockers of β-cell death
14. Role of protein kinase C in basal and hydrogen peroxide-stimulated NF-κB activation in the murine macrophage J774A. 1 cell line
15. Reduced activation of transcriptional factor AP-1 among peripheral blood T cells from elderly humans after PHA stimulation: Restorative effect of phorbol diesters
16. In vivo viral and cellular Jun complexes exhibit differential interaction with a number of in vitro generated 'AP-1- and CREB-like' target sequences
17. Selectivity of antibodies to estrogen receptors α and β (ERα and ERβ) for detecting DNA-bound ERα and ERβ in vitro
18. s protein in rat liver plasma membranes
19. 2 in NR8383 alveolar macrophages
20. Extracellular signal-regulated protein kinase (ERK)-dependent and ERK-independent pathways target STAT3 on serine-727 in human neutrophils stimulated by chemotactic factors and cytokines
21. Stimulation of the rat alveolar macrophage respiratory burst by extracellular adenine nucleotides
22. Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide
23. Modulation of the rat alveolar macrophage respiratory burst by hydroperoxide is calcium dependent
24. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
25. Modulation of activator protein-1 (AP-1) transcription factor and protein kinase C by hydrogen peroxide and D-alpha-tocopherol in vascular smooth muscle cells
26. 2 and tumor necrosis factor-alpha induce differential binding of the redox-responsive transcription factors AP-1 and NF-kappaB to the interleukin-8 promoter in endothelial and epithelial cells
27. Sublethal levels of oxidative stress stimulate transcriptional activation of c-jun and suppress IL-2 promoter activation in Jurkat T cells
28. 2 is directly related to increased proliferation and transformation of tracheal epithelial cells
29. 2 and diamide
30. Stimulus-specific regulation of chemokine expression involves differential activation of the redox-responsive transcription factors AP-1 and NF-κB
31. Activator protein-1 DNA binding activation by hydrogen peroxide in neuronal and astrocytic primary cultures of trisomy-16 and diploid mice
32. Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage
33. Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase
34. Priming of human alveolar macrophages and blood monocytes for superoxide anion release by interferons and lipopolysaccharide
35. Induction of soluble antitumoral mediators by synthetic analogues of bacterial lipoprotein in bone marrow-derived macrophages from LPS-responder and -nonresponder mice
36. Involvement of protein kinases in the potentiation of lipopolysaccharide-induced inflammatory mediator formation by thapsigargin in peritoneal macrophages
37. Alveolar macrophage-derived cytokines induce monocyte chemoattractant protein-1 expression from human pulmonary type II-like epithelial cells
38. Activation of NF κB by the respiratory burst of macrophages