NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway

Journal of Biological Chemistry

Volumn 277, Issue 50, 2002, Pages 48043-48050

  Salehi, Amir H ^a   Xanthoudakis, Steven ^b   Barker, Philip A ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME KINETICS; PHARMACOKINETICS; PROTEINS; SIGNALING;

CELL DEATH;

BIOCHEMISTRY;

CASPASE; CASPASE 3; CASPASE 7; CASPASE 9; CEP 1347; CYTOCHROME C; NEUROTROPHIN RECEPTOR; PROTEIN NRAGE; PROTEIN P75; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ADENOVIRUS; APOPTOSIS; ARTICLE; BINDING SITE; CELL DEATH; CELL TYPE; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CARBAZOLES; CASPASES; CYTOCHROME C GROUP; DNA-BINDING PROTEINS; ENZYME ACTIVATION; INDOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; PC12 CELLS; RATS; SIGNAL TRANSDUCTION;

ADENOVIRIDAE;

EID: 2242447082     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205324200     Document Type: Article

References (58)

1. Barrett G. L. (2000) Prog. Neurobiol. 61, 205-229
2. Davey, F., and Davies, A. M. (1998) Curr. Biol. 8, 915-918
3. Friedman, W. J. (2000) J. Neurosci. 20, 6340-6346
4. Bamji S. X., Majdan M., Pozniak, C. D. Belliveau, D. J., Aloyz, R., Kohn J., Causing, C. G., and Miller, F. D. (1998) J. Cell Biol. 140, 911-923
5. Soilu-Hanninen, M., Ekert, P., Bucci, T., Syroid, D., Bartlett, P. F., and Kilpatrick, T. J. (1999) J. Neurosci. 19, 4828-4838
6. Bunone, G., Mariotti, A., Compagni, A., Morandi, E., and Della Valle, G. (1997) Oncogene 14, 1463-1470
7. Frago, L. M., Leon, Y., de la Rosa, E. J., Gomez-Munoz, A., and Varela-Nieto, I. (1998) J. Cell Sci. 111 (Pt. 5), 549-556
8. Majdan, M., Lachance, C., Gloster, A., Aloyz, R., Zeindler, C., Bamji, S., Bhakar, A., Belliveau, D., Fawcett, J., Miller, F. D., and Barker, P. A. (1997) J. Neurosci. 17, 6988-6995
9. Frade, J. M., Rodriguez-Tebar, A., and Barde, Y. A. (1996) Nature 383, 166-168
10. Frade, J. M., and Barde, Y. A. (1999) Development 126, 683-690
11. Agerman, K., Baudet, C., Fundin, B., Willson, C., and Ernfors, P. (2000) Mol. Cell. Neurosci. 16, 258-268
12. Casaccia-Bonnefil, P., Carter, B. D., Dobrowsky, R. T., and Chao, M. V. (1999) Nature 383, 716-719
13. Yoon, S. O., Casaccia-Bonnefil, P., Carter, B., and Chao, M. V. (1998) J. Neurosci. 18, 3273-3281
14. Roux, P. P., Bhakar, A. L., Kennedy, T. E., and Barker, P. A. (2001) J. Biol. Chem. 276, 23097-23104
15. Harrington, A. W., Kim, J. Y., and Yoon, S. O. (2002) J. Neurosci. 22, 156-166
16. Casademunt, E., Carter, B. D., Benzel, I., Frade, J. M., Dechant, G., and Barde, Y. A. (1999) EMBO J. 18, 6050-6061
17. Mukai, J., Hachiya, T., Shoji-Hoshino, S., Kimura, M. T., Nadano, D., Suvanto, P., Hanaoka, T., Li, Y., Irie, S., Greene, L. A., and Sato, T. A. (2000) J. Biol. Chem. 275, 17566-17570
18. Salehi, A. H., Roux, P. P., Kubu, C. J., Zeindler, C., Bhakar, A., Tannis, L. L., Verdi, J. M., and Barker, P. A. (2000) Neuron 27, 279-288
19. Harding, T. C., Xue, L., Bienemann, A., Haywood, D., Dickens, M., Tolkovsky, A. M., and Uney, J. B. (2001) J. Biol. Chem. 276, 4531-4534
20. Whitfield, J., Neame, S. J., Paquet, L., Bernard, O., and Ham, J. (2001) Neuron 29, 629-643
21. Roux, P. P., Dorval, G., Boudreau, M., Angers-Loustau, A., Morris, S. J., Makkerh, J., and Barker, P. A. (2002) J. Biol. Chem., in press
22. Quantum Biotechnology, Inc. (2000) Ad Easy Vector System Application Manual, Version 1.2, Quantum Biotechnologies, Montreal, Canada
23. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
24. Samali, A., Cai, J., Zhivotovsky, B., Jones, D. P., and Orrenius, S. (1999) EMBO J. 18, 2040-2048
25. Budihardjo, I., Oliver, H., Lutter, M., Luo, X., and Wang, X. (1999) Annu. Rev. Cell Dev. Biol. 15, 269-290
26. Kidd, V. J. (1998) Annu. Rev. Physiol. 60, 533-573
27. Gorman, A. M., Ceccatelli, S., and Orrenius, S. (2000) Dev. Neurosci. 2(5-6), 348-358
28. Li, H., Zhu, H., Xu, C. J., and Yuan, J. (1998) Cell 94, 491-501
29. Ham, J., Eilers, A., Whitfield, J., Neame, S. J., and Shah, B. (2000) Biochem. Pharmacol. 60, 1015-1021
30. Chen, Y. R., and Tan, T. H. (2000) Int. J. Oncol. 16, 651-662
31. Angel, P., Hattori, K., Smeal, T., and Karin, M. (1988) Cell 55, 875-885
32. Pulverer, B. J., Kyriakis, J. M., Avruch, J., Nikolakaki, E., and Woodgett, J. R. (1991) Nature 353, 670-674
33. Maroney, A. C., Glicksman, M. A., Basma, A. N., Walton, K. M., Knight, E., Jr., Murphy, C. A., Bartlett, B. A., Finn, J. P., Angeles, T., Matsuda, Y., Neff, N. T., and Dionne, C. A. (1998) J. Neurosci. 18, 104-111
34. Maroney, A. C., Finn, J. P., Bozyczko-Coyne, D., O'Kane, T. M., Neff, N. T., Tolkovsky, A. M., Park, D. S., Yan, C. Y., Troy, C. V., Troy, C. M., and Greene, L. A. (1999) J. Neurochem. 73, 1901-1912
35. Maroney, A. C., Finn, J. P., Connors, T. J., Durkin, J. T., Angeles, T., Gessner, G., Xu, Z., Meyer, S. L., Savage, M. J., Greene, L. A., Scott, R. W., and Vaught, J. L. (2001) J. Biol. 276, 25302-25308
36. Mota, M., Reeder, M., Chernoff, J., and Bazenet, C. E. (2001) J. Neurosci. 21, 4949-4957
37. Xu, Z., Maroney, A. C., Dobrzanski, P., Kukekov, N. V., and Greene, L. A. (2001) Mol. Cell. Biol. 21, 4713-4724
38. Ham, J., Babij, C., Whitfield, J., Pfarr, C. M., Lallemand, D., Yaniv, M., and Rubin, L. L. (1995) Neuron 14, 927-939
39. Leppa, S., Eriksson, M., Saffrich, R., Ansorge, W., and Bohmann, D. (2001) Mol. Cell. Biol. 21, 4369-4378
40. Almeida, E. A., Ilic, D., Han, Q., Hauck, C. R., Jin, F., Kawakatsu, H., Schlaepfer, D. D., and Damsky, C. H. (2000) J. Cell Biol. 149, 741-754
41. Kuan, C. Y., Yang, D. D., Samanta Roy, D. R., Davis, R. J., Rakic, P., and Flavell, R. A. (1999) Neuron 22, 667-676
42. Frisch, S. M., Vuori, K., Kelaita, D., and Sicks, S. (1996) J. Cell Biol. 135, 1377-1382
43. Cahill, M. A., Peter, M. E., Kischkel, F. C., Chinnaiyan, A. M., Dixit, V. M., Krammer, P. H., and Nordheim, A. (1996) Oncogene 13, 2087-2096
44. Cardone, M. H., Salvesen, G. S., Widmann, C., Johnson, G., and Frisch, S. M. (1997) Cell 90, 315-323
45. Brann, A. B., Tcherpakov, M., Williams, I. M., Futerman, A. H., and Fainzilber, M. (2002) J. Biol. Chem. 277, 9812-9818
46. Gu, C., Casacia-Bonnefil, P., Srinivasan, A., and Chao, M. V. (1999) J. Neurosci. 19, 3043-3049
47. Coulson, E. J., Reid, K., Barrett, G. L., and Bartlett, P. F. (1999) J. Biol. Chem. 274, 16387-16391
48. Wang, X., Bauer, J. H., Li, Y., Shao, Z., Zetoune, F. S., Cattaneo, E., and Vincenz, C. (2001) J. Biol. Chem. 276, 33812-33820
49. Barker, P. A., and Salehi, A. (2002) J. Neurosci. Res. 67, 705-712
50. Jordan, B. W., Dinev, D., LeMellay, V., Troppmair, J., Gotz, R., Wixler, L., Sendtner, M., Ludwig, S., and Rapp, U. R. (2001) J. Biol. Chem. 276, 39985-39989
51. Kimura, M. T., Irie, S., Shoji-Hoshino, S., Mukai, J., Nadano, D., Oshimura, M., and Sato, T. A. (2001) J. Biol. Chem. 276, 17291-17300
52. Chittka, A., and Chao, M. V. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 10705-10710
53. Yamashita, T., Tucker, K. L., and Barde, Y. A. (1999) Neuron 24, 585-593
54. Khursigara, G., Bertin, J., Yano, H., Moffett, H., DiStefano, P. S., and Chao, M. V. (2001) J. Neurosci. 21, 5854-5863
55. Irie, S., Hachiya, T., Rabizadeh, S., Maruyama, W., Mukai, J., Li, Y., Reed, J. C., Bredesen, D. E., and Sato, T. A. (1999) FEBS Lett. 460, 191-198
56. Bradley, J. R., and Pober, J. S. (2001) Oncogene 20, 6482-6491
57. Khursigara, G., Orlinick, J. R., and Chao, M. V. (1999) J. Biol. Chem. 274, 2597-2600
58. Ye, X., Mehlen, P., Rabizadeh, S., VanArsdale, T., Zhang, H., Shin, H., Wang, J. J., Leo, E., Zapata, J., Hauser, C. A., Reed, J. C., and Bredesen, D. E. (1999) J. Biol. Chem. 274, 30202-30208