A unifying view of ageing and disease: The double-agent theory

Journal of Theoretical Biology

Volumn 225, Issue 4, 2003, Pages 531-540

  Lane, Nick ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Ageing; Double agent theory; Mitochondria; Oxidative stress; Redox switch

Indexed keywords

ANTIOXIDANT; ESTROGEN; FREE RADICAL; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

AGING; DISEASE;

AGED; AGING; ALLELE; ANIMAL; BIOLOGICAL MODEL; CHRONOSEQUENCE; DEGENERATIVE DISEASE; DNA POLYMORPHISM; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE THERAPY; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENETIC SELECTION; GENETIC SUSCEPTIBILITY; HORMONE SUBSTITUTION; HUMAN; IMMUNE SYSTEM; INFECTION; KNOCKOUT MOUSE; MALE; METABOLISM; METHODOLOGY; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHYSIOLOGY; PLEIOTROPY; PRIORITY JOURNAL; REVIEW; SEX DIFFERENTIATION; SIDE EFFECT; SUPPLEMENTATION; THEORETICAL MODEL; THEORY; TREATMENT FAILURE;

EID: 0242606930     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5193(03)00304-7     Document Type: Article

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