Cell line dependent involvement of ceramide in ultraviolet light-induced apoptosis

Molecular and Cellular Biochemistry

Volumn 219, Issue 1-2, 2001, Pages 21-27

  Chatterjee, M ^a   Wu, S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Ceramide; Sphingomyelinase; Ultraviolet light

Indexed keywords

CERAMIDE; DESIPRAMINE; DIACYLGLYCEROL KINASE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; STRESS ACTIVATED PROTEIN KINASE;

ANALYSIS; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CELL DEATH; CELL LINE; CELL PROTECTION; CELL STRAIN MCF 7; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROLYSIS; KIDNEY CELL; LEUKEMIA CELL LINE; LIPOGENESIS; LYMPHOCYTE; MEASUREMENT; MORPHOLOGY; SECOND MESSENGER; ULTRAVIOLET IRRADIATION; ULTRAVIOLET RADIATION; WESTERN BLOTTING;

APOPTOSIS; CELL LINE; CERAMIDES; DESIPRAMINE; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0035053367     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011083818452     Document Type: Article

References (21)

1. Ultraviolet B-radiation dose influences the induction of apoptosis and p53 in human keratinocytes
2. Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1)
3. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
4. The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation
5. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
6. Signal transduction through the sphingomyelin pathway
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11. Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase
12. Induction of stress-activated protein kinases/c-Jun N-terminal kinases by the p55 tumour necrosis factor receptor does not require sphingomyelinases
13. Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. Synthesis via ceramide from sphingomyelin
14. The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts
15. Stress signals for apoptosis: Ceramide and c-Jun kinase
16. Ceramide activates the stress-activated protein kinases
17. Analysis of human breast adenocarcinoma MCF-7 resistance to tumor necrosis factor-induced cell death. Lack of correlation between JNK activation and ceramide pathway
18. Daxx, a novel Fas-binding protein that activates JNK and apoptosis
19. Role for ceramide in cell cycle arrest
20. Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation
21. Fas-receptor and not TNFα-receptor is involved in UV-induced activation of acid sphingomyelinase