BLNK: A central linker protein in B cell activation

Immunity

Volumn 9, Issue 1, 1998, Pages 93-103

  Fu, Chong ^a   Turck, Christoph W ^b   Kurosaki, Tomohiro ^c   Chan, Andrew C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; HUMAN; HUMAN TISSUE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0032127159     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80591-9     Document Type: Article

References (50)

1. Bubeck-Wardenburg, J., Fu, C.F., Jackman, J., Flotow, H., Wilkinson, S., Williams, D., Kong, G.H., Johnson, R., Chan, A.C., and Findell, P. (1996). Phosphorylation of SLP-76 by the ZAP-70 protein tyrosine kinase is required for T cell receptor function. J. Biol. Chem. 271, 19641-19644.
2. Bustelo, X.R., and Barbacid, M. (1992). Tyrosine phosphorylation of the Vav proto-oncogene product in activated B cells. Science 256, 1196-1199.
3. Chan, A., Desai, D.M., and Weiss, A. (1994). Role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 14, 555-592.
4. Chan, A.C., Dalton, M., Johnson, R., Kong, G.-h., Wang, T., Thoma, R., and Kurosaki, T. (1995). Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14, 2499-2508.
5. Crespo, P., Bustelo, X.R., Aaroson, D.S., Coso, O.A., Lopez-Barahoma, M., Barbacid, M., and Gutkind, J.S. (1996). Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav. Oncogene 13, 455-460.
6. Crespo, P., Schuebel, K.E., Ostrum, A.A., Gutkind, J.S., and Bustelo, X.R. (1997). Phosphotyrosine-dependent activation of Rac-1 GDP/ GTP exchange by the Vav proto-oncogene product. Nature 385, 169-172.
7. D'Ambrosio, D., Hippen, K.L., and Cambier, J.C. (1996). Distinct mechanisms mediate SHC association with the activated and resting B cell antigen receptor. Eur. J. Immunol. 26, 1960-1965.
8. da Silva, A.J., Li, Z., de Vera, C., Canto, E., Findell, P., and Rudd, C.E. (1997). Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc. Natl. Acad. Sci. USA 94, 7493-7498.
9. DeFranco, A.L. (1997). The complexity of signaling pathways activated by the BCR. Curr. Opin. Immunol. 9, 296-308.
10. El-Hillal, O., Kurosaki, T., Yamamura, H., Kinet, J.-P., and Scharenberg, A.M. (1997). Syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction. Proc. Natl. Acad. Sci. USA 94, 1919-1924.
11. Fang, N., Motto, D.G., and Ross, S.E. (1996). Tyrosines 113, 128, and 145 of SLP-76 are required for optimal augmentation of NFAT promoter activity. J. Immunol. 157, 3769-3773.
12. Fu, C., and Chan, A.C. (1997). Identification of two tyrosine phosphoproteins, pp70 and pp68, that interact with PLCγ, Grb2, and Vav following B cell antigen receptor activation. J. Biol. Chem. 272, 27362-27368.
13. Goga, A., McLaughlin, J., Afar, D.E.H., Saffran, D.C., and Witte, O.N. (1995). Alternative signals to Ras for hematopoietic transformation by the BCR-ABL oncogene. Cell 82, 981-988.
14. Gotoh, N., Tojo, A., Muroya, K., Hashimoto, Y., Hattori, S., Nakamura, S., Takenawa, T., Yazaki, Y., and Shibuya, M. (1994). Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH assoication and retains mitogenic activity. Proc. Natl. Acad. Sci. USA 91, 167-171.
15. Harmer, S.L., and DeFranco, A.L. (1997). Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes. Mol. Cell. Biol. 17, 4087-4095.
16. Harwood, A.E., and Cambier, J.C. (1993). B cell antigen receptor cross-linking triggers rapid protein kinase C independent activation of p21ras. J. Immunol. 151, 4513-4522.
17. Healy, J.I., Dolmetsch, R.E., Timmerman, L.A., Cyster, J.G., Thomas, M.L., Crabtree, G.R., Lewis, R.S., and Goodnow, C.C. (1997). Different nuclear signals are activated by the B cell receptor during positive versus negative signaling. Immunity 6, 419-428.
18. Hellman, U., Wernstedt, C., Gonez, J., and Heldin, C.H. (1995). Improvement of an in-gel digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. Anal. Biochem. 224, 451-455.
19. Jackman, J.K., Motto, D.G., Sun, Q., Tanemoto, M., Turck, C.W., Peltz, G.A., Koretzky, G.A., and Findell, P.R. (1995). Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J. Biol. Chem. 270, 7029-7032.
20. Kong, G.H., Bu, J.Y., Kurosaki, T., Shaw, A.S., and Chan, A.C. (1995). Reconstitution of syk function by the ZAP-70 protein tyrosine kinase. Immunity 2, 485-492.
21. Kurosaki, T., and Kurosaki, M. (1997). Transphosphorylation of Bruton's tyrosine kinase on tyrosine 551 is critial for B cell antigen receptor function. J. Biol. Chem. 272, 15595-15598.
22. Kurosaki, T., Takata, M., Yamanashi, Y., Inazu, T., Taniguchi, T., Yamamoto, T., and Yamamura, H. (1994). Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling. J. Exp. Med. 179, 1725-1729.
23. Law, C.-L., Chandra, K.A., Sidorenko, S.P., and Clark, E.A. (1996). Phospholipase C-γ1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk. Mol. Cell. Biol. 16, 1305-1315.
24. McFarland, C., Pingel, J., and Thomas, M.L. (1997). Definition of amino acid sufficient for plasma membrane assoication of CD45 and CD45-associated protein. Biochemistry 36, 7169-7175.
25. Musci, M.A., Hendricks-Taylor, L.R., Motto, D.G., Paskind, M., Kamens, J., Turck, C.W., and Koretzky, G.A. (1997a). Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases. J. Biol. Chem. 272, 11674-11677.
26. Musci, M.A., Motto, D.G., Ross, S.E., Fang, N., and Koretzky, G.A. (1997b). Three domains of SLP-76 are required for its optimal function in a T cell line. J. Immunol. 159, 1639-1647.
27. Nagai, K., Takata, M., Yamamura, H., and Kurosaki, T. (1995). Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell receptor signaling. J. Biol. Chem. 270, 6824-6829.
28. Onodera, H., Motto, D.G., Koretzky, G.A., and Rothstein, D.M. (1996). Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase. J. Biol. Chem. 271, 22225-22230.
29. Raab, M., da Silva, J., Findell, P.R., and Rudd, C.E. (1997). Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCRζ/CD3 induction of interleukin-2. Immunity 6, 155-164.
30. Ranger, A.M., Hodge, M.R., Gravallese, E.M., Oukka, M., Davidson, L., Alt, F.W., de la Brousse, F.C., Hoey, T., Grusby, M., and Glimcher, L.H. (1998). Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity 8, 125-134.
31. Rao, A., Luo, C., and Hogan, P.G. (1997). Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 15, 707-747.
32. Reth, M., and Wienands, J. (1997). Initiation and processing of signals from the B cell antigen receptor. Annu. Rev. Immunol. 15, 453-479.
33. Richards, J.D., Gold, M.R., Hourihane, S.L., DeFranco, A.L., and Matsuuchi, L. (1996). Reconstitution of B cell antigen receptor-induced signaling events in a non-lymphoid cell line by expressing the Syk protein-tyrosine kinase. J. Biol. Chem. 271, 6458-6466.
34. Saxton, T.M., van Oostveen, I., Bowtell, D., Aebersold, R., and Gold, M.R. (1994). B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoportein actiators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine phosphorylated protein. J. Immunol. 153, 623-636.
35. Schlessinger, J. (1994). SH2/SH3 signaling proteins. Curr. Opin. Genet. Develop. 4, 25-30.
36. Schlessinger, J. (1997). Direct binding and activation of receptor tyrosine kinases by collagen. Cell 91, 869-872.
37. Secrist, J.P., Burns, L.A., Karnitz, L., Koretzky, G.A., and Abraham, R.T. (1993). Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J. Biol. Chem. 268, 5886-5893.
38. Simon, J.A., and Schreiber, S.L. (1995). Grb2 SH3 binding to peptides from Sos: evaluation of a general model for SH3-ligand interations. Chem. Biol. 2, 53-60.
39. Smit, L., deVries-Smits, A.M., Bos, J.L., and Borst, J. (1994). B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins. J. Biol. Chem. 269, 20209-20212.
40. Songyang, Z., Shoelson, S.E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W., King, F., Roberts, T., Ratnofsky, S., Lechleider, R.J., et al. (1993). SH2 domains recognize specific phosphopeptide sequences. Cell 72, 767-778.
41. Songyang, Z., Shoelson, S.E., McGlade, J., Olivier, P., Pawson, T., Bustello, X.R., Barbacid, M., Sabe, H., Hanafusa, H., Yi, T., et al. (1994). Specific motifs recognized by the SH2 domains of csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol. Cell. Biol. 14, 2777-2785.
42. Sun, X.J., Rothenberg, P., Kahn, C.R., Backer, J.M., Araki, E., Wilden, P.A., Cahill, D.A., Goldstein, B.J., and White, M.F. (1991). Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352, 73-77.
43. Takata, M., and Kurosaki, T. (1996). A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. J. Exp. Med. 184, 31-40.
44. 2+ mobilization through distinct pathways. EMBO J. 13, 1341-1349.
45. Teramoto, H., Salem, P., Robbins, K.C., Bustelo, X.R., and Gutkind, J.S. (1997). Tyrosine phosphorylation of the vav proto-oncogene products links Fc epsilonR1 to the Rac1-JNK pathway. J. Biol. Chem. 272, 10751-10755.
46. Tuosto, L., Michel, F., and Acuto, O. (1996). p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells. J. Exp. Med. 184, 1161-1166.
47. Ullrich, A., and Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
48. Wu, J., Motto, D.G., Koretzky, G.A., and Weiss, A. (1996). Vav and SLP-76 interact and functionally cooperative in IL-2 gene activation. Immunity 4, 593-602.
49. Yoshida, H., Nishina, H., Takimoto, H., Marengere, L.E.M., Wakeham, A.C., Bouchard, D., Kong, Y.-Y., Ohteki, T., Shahinian, A., Bachmann, M., et al. (1998). The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity 8, 115-124.
50. Zhang, W., Sloan-Lancaster, J., Kitchen, J., Trible, R.P., and Samelson, L.E. (1998). LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92, 83-92.