B Cells Acquire Particulate Antigen in a Macrophage-Rich Area at the Boundary between the Follicle and the Subcapsular Sinus of the Lymph Node

Immunity

Volumn 27, Issue 1, 2007, Pages 160-171

  Carrasco, Yolanda R ^a   Batista, Facundo D ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

Author keywords

CELLIMMUNO; MOLIMMUNO

Indexed keywords

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; LYMPH FOLLICLE; LYMPH NODE CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCAPSULAR SINUS; T LYMPHOCYTE; TISSUE STRUCTURE;

ANIMALS; ANTIGEN PRESENTATION; B-LYMPHOCYTE SUBSETS; CELLS, CULTURED; EPITOPES, B-LYMPHOCYTE; KINETICS; LYMPH NODES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; PARTICLE SIZE; PROTEIN TRANSPORT;

EID: 34447623566     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2007.06.007     Document Type: Article

References (45)

1. Allen C.D., Okada T., Tang H.L., and Cyster J.G. Imaging of germinal center selection events during affinity maturation. Science 315 (2007) 528-531
2. Balazs M., Martin F., Zhou T., and Kearney J. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 17 (2002) 341-352
3. Barcia C., Thomas C.E., Curtin J.F., King G.D., Wawrowsky K., Candolfi M., Xiong W.D., Liu C., Kroeger K., Boyer O., et al. In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain. J. Exp. Med. 203 (2006) 2095-2107
4. Batista F.D., Iber D., and Neuberger M.S. B cells acquire antigen from target cells after synapse formation. Nature 411 (2001) 489-494
5. Bergtold A., Desai D.D., Gavhane A., and Clynes R. Cell surface recycling of internalized antigen permits dendritic cell priming of B cells. Immunity 23 (2005) 503-514
6. Berney C., Herren S., Power C.A., Gordon S., Martinez-Pomares L., and Kosco-Vilbois M.H. A member of the dendritic cell family that enters B cell follicles and stimulates primary antibody responses identified by a mannose receptor fusion protein. J. Exp. Med. 190 (1999) 851-860
7. Brown J.C., De Jesus D.G., Holborow E.J., and Harris G. Lymphocyte-mediated transport of aggregated human gamma-globulin into germinal centre areas of normal mouse spleen. Nature 228 (1970) 367-369
8. Carrasco Y.R., and Batista F.D. B cell recognition of membrane-bound antigen: An exquisite way of sensing ligands. Curr. Opin. Immunol. 18 (2006) 286-291
9. Carrasco Y.R., and Batista F.D. B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1. EMBO J. 25 (2006) 889-899
10. Carrasco Y.R., Fleire S.J., Cameron T., Dustin M.L., and Batista F.D. LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation. Immunity 20 (2004) 589-599
11. Colino J., Shen Y., and Snapper C.M. Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms. J. Exp. Med. 195 (2002) 1-13
12. Davis D.M., Chiu I., Fassett M., Cohen G.B., Mandelboim O., and Strominger J.L. The human natural killer cell immune synapse. Proc. Natl. Acad. Sci. USA 96 (1999) 15062-15067
13. Delamarre L., Pack M., Chang H., Mellman I., and Trombetta E.S. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science 307 (2005) 1630-1634
14. Ferguson A.R., Youd M.E., and Corley R.B. Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int. Immunol. 16 (2004) 1411-1422
15. Fleire S.J., Goldman J.P., Carrasco Y.R., Weber M., Bray D., and Batista F.D. B cell ligand discrimination through a spreading and contraction response. Science 312 (2006) 738-741
16. Garside P., Ingulli E., Merica R.R., Johnson J.G., Noelle R.J., and Jenkins M.K. Visualization of specific B and T lymphocyte interactions in the lymph node. Science 281 (1998) 96-99
17. Grakoui A., Bromley S.K., Sumen C., Davis M.M., Shaw A.S., Allen P.M., and Dustin M.L. The immunological synapse: A molecular machine controlling T cell activation. Science 285 (1999) 221-227
18. Gray D., Kumararatne D.S., Lortan J., Khan M., and MacLennan I.C. Relation of intra-splenic migration of marginal zone B cells to antigen localization on follicular dendritic cells. Immunology 52 (1984) 659-669
19. Gray D., MacLennan I.C., Platteau B., Bazin H., Lortan J., and Johnson G.D. Evidence that static but not recirculating B cells are responsible for antibody production against dinitrophenol on neutral polysaccharide, a TI-2 antigen. Adv. Exp. Med. Biol. 186 (1985) 437-442
20. Gretz J.E., Norbury C.C., Anderson A.O., Proudfoot A.E., and Shaw S. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 192 (2000) 1425-1440
21. Hauser A.E., Junt T., Mempel T.R., Sneddon M.W., Kleinstein S.H., Henrickson S.E., von Andrian U.H., Shlomchik M.J., and Haberman A.M. Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. Immunity 26 (2007) 655-667
22. Huang A.Y., Qi H., and Germain R.N. Illuminating the landscape of in vivo immunity: Insights from dynamic in situ imaging of secondary lymphoid tissues. Immunity 21 (2004) 331-339
23. Humphrey J.H., and Grennan D. Different macrophage populations distinguished by means of fluorescent polysaccharides. Recognition and properties of marginal-zone macrophages. Eur. J. Immunol. 11 (1981) 221-228
24. Kamath A.T., Henri S., Battye F., Tough D.F., and Shortman K. Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood 100 (2002) 1734-1741
25. Kang Y.S., Yamazaki S., Iyoda T., Pack M., Bruening S.A., Kim J.Y., Takahara K., Inaba K., Steinman R.M., and Park C.G. SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran. Int. Immunol. 15 (2003) 177-186
26. Koppel E.A., Wieland C.W., van den Berg V.C., Litjens M., Florquin S., van Kooyk Y., van der Poll T., and Geijtenbeek T.B. Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection. Eur. J. Immunol. 35 (2005) 2962-2969
27. Krummel M.F., Sjaastad M.D., Wulfing C., and Davis M.M. Differential clustering of CD4 and CD3zeta during T cell recognition. Science 289 (2000) 1349-1352
28. Kwon D.S., Gregorio G., Bitton N., Hendrickson W.A., and Littman D.R. DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection. Immunity 16 (2002) 135-144
29. MacLennan I.C., Toellner K.M., Cunningham A.F., Serre K., Sze D.M., Zuniga E., Cook M.C., and Vinuesa C.G. Extrafollicular antibody responses. Immunol. Rev. 194 (2003) 8-18
30. Miller M.J., Wei S.H., Parker I., and Cahalan M.D. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296 (2002) 1869-1873
31. Möller G. Role of somatic mutation in the generation of lymphocyte diversity. Immunol. Rev. 96 (1987) 1-162
32. Monks C.R., Freiberg B.A., Kupfer H., Sciaky N., and Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395 (1998) 82-86
33. Okada T., Miller M.J., Parker I., Krummel M.F., Neighbors M., Hartley S.B., O'Garra A., Cahalan M.D., and Cyster J.G. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol. 3 (2005) e150
34. Pape K.A., Catron D.M., Itano A.A., and Jenkins M.K. The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity 26 (2007) 491-502
35. Qi H., Egen J.G., Huang A.Y., and Germain R.N. Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells. Science 312 (2006) 1672-1676
36. Reichert P., Reinhardt R.L., Ingulli E., and Jenkins M.K. Cutting edge: In vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells. J. Immunol. 166 (2001) 4278-4281
37. Schwickert T.A., Lindquist R.L., Shakhar G., Livshits G., Skokos D., Kosco-Vilbois M.H., Dustin M.L., and Nussenzweig M.C. In vivo imaging of germinal centres reveals a dynamic open structure. Nature 446 (2007) 83-87
38. Sixt M., Kanazawa N., Selg M., Samson T., Roos G., Reinhardt D.P., Pabst R., Lutz M.B., and Sorokin L. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 22 (2005) 19-29
39. Stinchcombe J.C., Bossi G., Booth S., and Griffiths G.M. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 15 (2001) 751-761
40. Stoll S., Delon J., Brotz T.M., and Germain R.N. Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296 (2002) 1873-1876
41. Szakal A.K., Holmes K.L., and Tew J.G. Transport of immune complexes from the subcapsular sinus to lymph node follicles on the surface of nonphagocytic cells, including cells with dendritic morphology. J. Immunol. 131 (1983) 1714-1727
42. Taylor P.R., Martinez-Pomares L., Stacey M., Lin H.H., Brown G.D., and Gordon S. Macrophage receptors and immune recognition. Annu. Rev. Immunol. 23 (2005) 901-944
43. Taylor P.R., Zamze S., Stillion R.J., Wong S.Y., Gordon S., and Martinez-Pomares L. Development of a specific system for targeting protein to metallophilic macrophages. Proc. Natl. Acad. Sci. USA 101 (2004) 1963-1968
44. White R.G., French V.I., and Stark J.M. A study of the localisation of a protein antigen in the chicken spleen and its relation to the formation of germinal centres. J. Med. Microbiol. 3 (1970) 65-83
45. Wykes M., Pombo A., Jenkins C., and MacPherson G.G. Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response. J. Immunol. 161 (1998) 1313-1319